CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp16 : CodonNum = 33 & Codon = agA

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF1ab/nsp16	33	S33R	S6831R	nonsyn	agT	agA	539	14	0.025974	20755-20757

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF1ab/nsp16	33	S33R	agT	agA	14	539	All	0.000003
ORF1ab/nsp16	33	S33R	agT	agA	1	4	B.1.1	0.000018
ORF1ab/nsp16	33	S33R	agT	agA	2	3	B.1.617.2	0.000008
ORF1ab/nsp16	33	S33R	agT	agA	1	2	B.1.177	0.000013
ORF1ab/nsp16	33	S33R	agT	agA	2	2	B.1.323	0.041667
ORF1ab/nsp16	33	S33R	agT	agA	1	1		0.055556
ORF1ab/nsp16	33	S33R	agT	agA	1	1	AY.6	0.000041
ORF1ab/nsp16	33	S33R	agT	agA	1	1	AY.91	0.00073
ORF1ab/nsp16	33	S33R	agT	agA	1	1	AY.99	0.001049
ORF1ab/nsp16	33	S33R	agT	agA	1	1	B.1.1.37	0.000193
ORF1ab/nsp16	33	S33R	agT	agA	1	1	B.1.221	0.000071
ORF1ab/nsp16	33	S33R	agT	agA	1	1	B.1.235	0.002519
ORF1ab/nsp16	33	S33R	agT	agA	1	1	B.1.427	0.00005

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.