CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp16 : CodonNum = 238 & Codon = caT

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF1ab/nsp16	238	Q238H	Q7036H	nonsyn	caG	caT	59574	59532	0.999295	21370-21372

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF1ab/nsp16	238	Q238H	caG	caT	59532	59574	All	0.011386
ORF1ab/nsp16	238	Q238H	caG	caT	25330	25330	AY.39	0.625942
ORF1ab/nsp16	238	Q238H	caG	caT	24691	24691	AY.39.1	0.978094
ORF1ab/nsp16	238	Q238H	caG	caT	4272	4276	B.1.617.2	0.016086
ORF1ab/nsp16	238	Q238H	caG	caT	1366	1366	AY.39.1.1	0.989855
ORF1ab/nsp16	238	Q238H	caG	caT	648	648	AY.39.2	0.998459
ORF1ab/nsp16	238	Q238H	caG	caT	520	522	AY.4	0.000809
ORF1ab/nsp16	238	Q238H	caG	caT	396	413	B.1.1.7	0.000355
ORF1ab/nsp16	238	Q238H	caG	caT	246	246	AY.25	0.00148
ORF1ab/nsp16	238	Q238H	caG	caT	206	206	AY.44	0.001254
ORF1ab/nsp16	238	Q238H	caG	caT	203	203	P.1	0.003198
ORF1ab/nsp16	238	Q238H	caG	caT	145	145	AY.16	0.055049
ORF1ab/nsp16	238	Q238H	caG	caT	113	114	AY.43	0.000501
ORF1ab/nsp16	238	Q238H	caG	caT	103	103	B.1.1	0.001869
ORF1ab/nsp16	238	Q238H	caG	caT	91	91	B.1.2	0.000801
ORF1ab/nsp16	238	Q238H	caG	caT	88	89	AY.103	0.000546
ORF1ab/nsp16	238	Q238H	caG	caT	83	83	B.1.177.78	0.805825
ORF1ab/nsp16	238	Q238H	caG	caT	79	79	AY.4.2	0.001713
ORF1ab/nsp16	238	Q238H	caG	caT	63	67	B.1	0.000577
ORF1ab/nsp16	238	Q238H	caG	caT	60	60	B.1.160.20	0.535714
ORF1ab/nsp16	238	Q238H	caG	caT	54	54	AY.26	0.001529
ORF1ab/nsp16	238	Q238H	caG	caT	49	49	B.1.160	0.001528
ORF1ab/nsp16	238	Q238H	caG	caT	29	29	AY.23.1	0.012104
ORF1ab/nsp16	238	Q238H	caG	caT	26	26	B.1.429	0.000612
ORF1ab/nsp16	238	Q238H	caG	caT	25	25	B.1.526	0.000588
ORF1ab/nsp16	238	Q238H	caG	caT	25	25	B.1.621	0.002213
ORF1ab/nsp16	238	Q238H	caG	caT	24	24	AY.108	0.026461
ORF1ab/nsp16	238	Q238H	caG	caT	23	23	AY.117	0.001944
ORF1ab/nsp16	238	Q238H	caG	caT	21	21	AY.33	0.001402
ORF1ab/nsp16	238	Q238H	caG	caT	20	20	AY.36	0.002964
ORF1ab/nsp16	238	Q238H	caG	caT	18	18	AY.70	0.003753
ORF1ab/nsp16	238	Q238H	caG	caT	17	17	AY.20	0.000661
ORF1ab/nsp16	238	Q238H	caG	caT	13	15	AY.102	0.000345
ORF1ab/nsp16	238	Q238H	caG	caT	15	15	B.1.177	0.000198
ORF1ab/nsp16	238	Q238H	caG	caT	15	15	B.1.258	0.000998
ORF1ab/nsp16	238	Q238H	caG	caT	14	14	AY.9.2	0.000514
ORF1ab/nsp16	238	Q238H	caG	caT	12	13	AY.47	0.000373
ORF1ab/nsp16	238	Q238H	caG	caT	13	13	AY.92	0.003735
ORF1ab/nsp16	238	Q238H	caG	caT	13	13	B.1.1.39	0.006626
ORF1ab/nsp16	238	Q238H	caG	caT	13	13	B.1.351	0.000386
ORF1ab/nsp16	238	Q238H	caG	caT	12	13	P.1.14	0.000574
ORF1ab/nsp16	238	Q238H	caG	caT	12	12	Q.1	0.001516
ORF1ab/nsp16	238	Q238H	caG	caT	9	9	AY.30	0.003562
ORF1ab/nsp16	238	Q238H	caG	caT	9	9	AY.46.6	0.00065
ORF1ab/nsp16	238	Q238H	caG	caT	9	9	B.1.293	0.1125
ORF1ab/nsp16	238	Q238H	caG	caT	9	9	B.1.438.1	0.000965
ORF1ab/nsp16	238	Q238H	caG	caT	9	9	B.1.524	0.012658
ORF1ab/nsp16	238	Q238H	caG	caT	8	8	AY.116	0.002294
ORF1ab/nsp16	238	Q238H	caG	caT	8	8	AY.119	0.000282
ORF1ab/nsp16	238	Q238H	caG	caT	8	8	AY.42	0.000322
ORF1ab/nsp16	238	Q238H	caG	caT	4	8	AY.61	0.000419
ORF1ab/nsp16	238	Q238H	caG	caT	7	7	A.2	0.004633
ORF1ab/nsp16	238	Q238H	caG	caT	6	6	AY.4.5	0.000645
ORF1ab/nsp16	238	Q238H	caG	caT	6	6	AY.75	0.000336
ORF1ab/nsp16	238	Q238H	caG	caT	6	6	AY.87	0.004996
ORF1ab/nsp16	238	Q238H	caG	caT	5	5	AY.113	0.000712
ORF1ab/nsp16	238	Q238H	caG	caT	5	5	AY.23	0.000349
ORF1ab/nsp16	238	Q238H	caG	caT	5	5	AY.3	0.00005
ORF1ab/nsp16	238	Q238H	caG	caT	5	5	AY.98.1	0.000242
ORF1ab/nsp16	238	Q238H	caG	caT	5	5	B.1.1.284	0.000537
ORF1ab/nsp16	238	Q238H	caG	caT	5	5	B.1.369	0.001426
ORF1ab/nsp16	238	Q238H	caG	caT	5	5	B.1.525	0.000566
ORF1ab/nsp16	238	Q238H	caG	caT	5	5	C.37	0.00058
ORF1ab/nsp16	238	Q238H	caG	caT	4	4	AY.101	0.001962
ORF1ab/nsp16	238	Q238H	caG	caT	4	4	AY.120	0.000149
ORF1ab/nsp16	238	Q238H	caG	caT	4	4	AY.38	0.001997
ORF1ab/nsp16	238	Q238H	caG	caT	4	4	AY.45	0.000487
ORF1ab/nsp16	238	Q238H	caG	caT	4	4	B.1.1.189	0.006051
ORF1ab/nsp16	238	Q238H	caG	caT	4	4	B.1.1.311	0.001433
ORF1ab/nsp16	238	Q238H	caG	caT	4	4	B.1.1.519	0.000159
ORF1ab/nsp16	238	Q238H	caG	caT	4	4	B.1.1.521	0.02139
ORF1ab/nsp16	238	Q238H	caG	caT	4	4	B.1.157	0.01194
ORF1ab/nsp16	238	Q238H	caG	caT	3	4	B.1.177.21	0.000229
ORF1ab/nsp16	238	Q238H	caG	caT	4	4	B.1.427	0.000202
ORF1ab/nsp16	238	Q238H	caG	caT	4	4	C.16	0.004242
ORF1ab/nsp16	238	Q238H	caG	caT	4	4	C.38	0.032258
ORF1ab/nsp16	238	Q238H	caG	caT	3	3	AY.118	0.000188
ORF1ab/nsp16	238	Q238H	caG	caT	3	3	AY.46.1	0.00308
ORF1ab/nsp16	238	Q238H	caG	caT	3	3	AY.80	0.003386
ORF1ab/nsp16	238	Q238H	caG	caT	3	3	AY.95	0.002283
ORF1ab/nsp16	238	Q238H	caG	caT	3	3	B.1.1.198	0.004405
ORF1ab/nsp16	238	Q238H	caG	caT	3	3	B.1.1.214	0.000166
ORF1ab/nsp16	238	Q238H	caG	caT	3	3	B.1.1.318	0.000905
ORF1ab/nsp16	238	Q238H	caG	caT	3	3	B.1.234	0.000396
ORF1ab/nsp16	238	Q238H	caG	caT	3	3	B.1.308	0.103448
ORF1ab/nsp16	238	Q238H	caG	caT	3	3	B.1.311	0.000824
ORF1ab/nsp16	238	Q238H	caG	caT	3	3	B.1.313	0.019737
ORF1ab/nsp16	238	Q238H	caG	caT	3	3	B.1.337	0.01676
ORF1ab/nsp16	238	Q238H	caG	caT	3	3	B.1.36	0.000438
ORF1ab/nsp16	238	Q238H	caG	caT	3	3	B.1.558	0.013699
ORF1ab/nsp16	238	Q238H	caG	caT	3	3	B.1.564	0.001278
ORF1ab/nsp16	238	Q238H	caG	caT	3	3	B.1.595.4	0.021898
ORF1ab/nsp16	238	Q238H	caG	caT	3	3	D.2	0.000225
ORF1ab/nsp16	238	Q238H	caG	caT	3	3	P.1.15	0.000697
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	AY.111	0.000366
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	AY.28	0.003781
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	AY.4.3	0.001684
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	AY.46	0.000208
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	AY.67	0.000929
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	B.1.1.222	0.000408
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	B.1.1.33	0.000842
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	B.1.1.55	0.025974
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	B.1.111	0.00235
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	B.1.192	0.018519
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	B.1.258.14	0.001961
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	B.1.415.1	0.015152
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	B.1.459	0.008163
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	B.1.466.2	0.000782
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	B.1.530	0.014286
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	B.1.595.1	0.011696
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	B.1.617.1	0.000258
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	B.1.628	0.000705
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	B.40	0.000729
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	C.26	0.014706
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	P.1.4	0.001953
ORF1ab/nsp16	238	Q238H	caG	caT	2	2	W.3	0.010526
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	A	0.000387
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	A.21	0.00277
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	A.23.1	0.000704
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	AA.8	0.022222
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	AU.3	0.00211
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	AY.105	0.000643
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	AY.106	0.000335
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	AY.110	0.000113
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	AY.116.1	0.000311
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	AY.120.2.1	0.000498
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	AY.34	0.000097
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	AY.4.2.1	0.000149
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	AY.40	0.000964
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	AY.5	0.000021
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	AY.65	0.000533
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	AY.7.2	0.000559
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	AY.9	0.000068
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	AY.91	0.00073
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	AY.93	0.000273
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.1.1	0.000327
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.1.157	0.000913
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.1.25	0.000569
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.1.291	0.000742
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.1.312	0.001912
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.1.316	0.000925
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.1.369	0.000446
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.1.372	0.000689
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.1.380	0.009804
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.1.389	0.006061
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.1.398	0.003226
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.1.402	0.011111
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.1.453	0.008475
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.1.51	0.001718
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.1.522	0.017241
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.1.70	0.000341
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.110.3	0.000718
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.160.18	0.007299
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.177.11	0.001698
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.177.31	0.011494
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.177.33	0.001645
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.177.44	0.000519
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.177.73	0.000566
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.177.81	0.000189
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.177.82	0.000477
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.177.83	0.001481
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.214.2	0.0006
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.221	0.000071
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.239	0.001221
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.247	0.014925
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.36.17	0.000494
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.36.29	0.000517
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.36.7	0.004
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.39	0.003906
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.400	0.000429
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.411	0.003704
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.416.1	0.001563
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.428	0.00102
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.438	0.006536
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.470	0.001404
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.473	0.019231
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.497	0.000315
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.538	0.008065
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.559	0.025
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.576	0.000907
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.577	0.000687
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.580	0.004065
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.596.1	0.009346
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.609	0.000479
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.623	0.000536
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.627	0.00202
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.1.631	0.003367
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.29	0.003509
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.6	0.00091
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	B.6.6	0.000889
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	C.36	0.000911
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	P.1.12	0.000484
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	P.1.7	0.000319
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	P.2	0.000187
ORF1ab/nsp16	238	Q238H	caG	caT	1	1	Q.4	0.000455

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.