CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp16 : CodonNum = 143

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp16143N143NN6941NsynaaTaaC33963396121085-21087
ORF1ab/nsp16143N143HN6941HnonsynAaTCaC3033020.996721085-21087
ORF1ab/nsp16143N143HN6941HnonsynAatCat30310.0033003321085-21087
ORF1ab/nsp16143N143delN6941deldelAAT---4545121085-21087
ORF1ab/nsp16143N143DN6941DnonsynAatGat99121085-21087
ORF1ab/nsp16143N143KN6941KnonsynaaTaaA640.66666721085-21087
ORF1ab/nsp16143N143KN6941KnonsynaaTaaG620.33333321085-21087
ORF1ab/nsp16143N143SN6941SnonsynaAtaGt44121085-21087
ORF1ab/nsp16143N143YN6941YnonsynAatTat22121085-21087
ORF1ab/nsp16143N143del2N6941del2delaATa--210.521085-21087
ORF1ab/nsp16143N143del2N6941del2delAAt--t210.521085-21087
ORF1ab/nsp16143N143IN6941InonsynaAtaTt11121085-21087
ORF1ab/nsp16143N143MN6941MnonsynaATaTG11121085-21087
ORF1ab/nsp16143N143del1N6941del1delAat-at11121085-21087

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp16143N143NaaTaaC33963396All0.00065
ORF1ab/nsp16143N143NaaTaaC16941694AY.9.20.06222
ORF1ab/nsp16143N143NaaTaaC925925AY.1030.005743
ORF1ab/nsp16143N143HAaTCaC302303All0.000058
ORF1ab/nsp16143N143HAatCat1303All0
ORF1ab/nsp16143N143NaaTaaC293293B.1.1.70.000262
ORF1ab/nsp16143N143HAaTCaC9696AY.1030.000596
ORF1ab/nsp16143N143NaaTaaC5555B.1.20.000484
ORF1ab/nsp16143N143NaaTaaC4747B.1.617.20.000177
ORF1ab/nsp16143N143delAAT---4545All0.000009
ORF1ab/nsp16143N143HAaTCaC3838AY.1200.001413
ORF1ab/nsp16143N143HAaTCaC3838AY.40.000059
ORF1ab/nsp16143N143HAaTCaC3435B.1.1.70.00003
ORF1ab/nsp16143N143HAatCat135B.1.1.70.000001
ORF1ab/nsp16143N143NaaTaaC3131AY.250.000186
ORF1ab/nsp16143N143NaaTaaC2525AY.40.000039
ORF1ab/nsp16143N143NaaTaaC2525AY.440.000152
ORF1ab/nsp16143N143NaaTaaC2424B.1.177.40.005065
ORF1ab/nsp16143N143HAaTCaC2424B.1.177.40.005065
ORF1ab/nsp16143N143HAaTCaC2323AY.9.20.000845
ORF1ab/nsp16143N143NaaTaaC2020AY.1200.000744
ORF1ab/nsp16143N143NaaTaaC1414AY.30.000139
ORF1ab/nsp16143N143NaaTaaC1313B.4.80.928571
ORF1ab/nsp16143N143NaaTaaC1212B.1.1600.000374
ORF1ab/nsp16143N143delAAT---1111B.1.1.70.00001
ORF1ab/nsp16143N143NaaTaaC1111B.1.1770.000145
ORF1ab/nsp16143N143HAaTCaC1111B.1.617.20.000041
ORF1ab/nsp16143N143NaaTaaC1010AY.430.000044
ORF1ab/nsp16143N143NaaTaaC1010B.10.000092
ORF1ab/nsp16143N143NaaTaaC1010B.1.1.440.024096
ORF1ab/nsp16143N143NaaTaaC1010B.1.177.860.001835
ORF1ab/nsp16143N143DAatGat99All0.000002
ORF1ab/nsp16143N143NaaTaaC99B.1.1.2140.000499
ORF1ab/nsp16143N143HAaTCaC99B.1.1.440.021687
ORF1ab/nsp16143N143NaaTaaC99B.1.360.001313
ORF1ab/nsp16143N143NaaTaaC77AY.1020.000186
ORF1ab/nsp16143N143NaaTaaC66A0.002322
ORF1ab/nsp16143N143KaaTaaA46All0.000001
ORF1ab/nsp16143N143KaaTaaG26All0
ORF1ab/nsp16143N143NaaTaaC66AY.390.000148
ORF1ab/nsp16143N143HAaTCaC66AY.430.000027
ORF1ab/nsp16143N143NaaTaaC66B.1.4290.000141
ORF1ab/nsp16143N143NaaTaaC55AY.230.000349
ORF1ab/nsp16143N143delAAT---55AY.40.000008
ORF1ab/nsp16143N143NaaTaaC55AY.46.40.000823
ORF1ab/nsp16143N143NaaTaaC55AY.99.20.000461
ORF1ab/nsp16143N143NaaTaaC55B.1.10.000091
ORF1ab/nsp16143N143HAaTCaC55B.1.1770.000066
ORF1ab/nsp16143N143SaAtaGt44All0.000001
ORF1ab/nsp16143N143NaaTaaC44AY.4.40.001637
ORF1ab/nsp16143N143delAAT---44AY.4.50.00043
ORF1ab/nsp16143N143NaaTaaC44B.1.2430.000278
ORF1ab/nsp16143N143NaaTaaC44B.1.5770.002749
ORF1ab/nsp16143N143NaaTaaC33AY.200.000117
ORF1ab/nsp16143N143NaaTaaC33AY.260.000085
ORF1ab/nsp16143N143NaaTaaC33AY.450.000365
ORF1ab/nsp16143N143NaaTaaC33AY.470.000093
ORF1ab/nsp16143N143NaaTaaC33AY.910.002191
ORF1ab/nsp16143N143NaaTaaC33B.1.1.1530.003286
ORF1ab/nsp16143N143NaaTaaC33B.1.1.2770.002276
ORF1ab/nsp16143N143NaaTaaC33B.1.1.2840.000322
ORF1ab/nsp16143N143NaaTaaC33B.1.1.3480.002389
ORF1ab/nsp16143N143DAatGat33B.1.1.70.000003
ORF1ab/nsp16143N143NaaTaaC33B.1.2580.0002
ORF1ab/nsp16143N143NaaTaaC33B.1.5750.00091
ORF1ab/nsp16143N143NaaTaaC33P.10.000047
ORF1ab/nsp16143N143delAAT---33P.1.150.000697
ORF1ab/nsp16143N143delAAT---220.111111
ORF1ab/nsp16143N143YAatTat22All0
ORF1ab/nsp16143N143del2AAt--t12All0
ORF1ab/nsp16143N143del2aATa--12All0
ORF1ab/nsp16143N143delAAT---22AY.1030.000012
ORF1ab/nsp16143N143NaaTaaC22AY.1190.000071
ORF1ab/nsp16143N143HAaTCaC22AY.3.10.000171
ORF1ab/nsp16143N143NaaTaaC22AY.3.10.000171
ORF1ab/nsp16143N143SaAtaGt22AY.40.000003
ORF1ab/nsp16143N143NaaTaaC22AY.4.20.000043
ORF1ab/nsp16143N143HAaTCaC22AY.460.000208
ORF1ab/nsp16143N143NaaTaaC22AY.590.001059
ORF1ab/nsp16143N143NaaTaaC22AY.670.000929
ORF1ab/nsp16143N143NaaTaaC22AY.7.10.000225
ORF1ab/nsp16143N143NaaTaaC22AY.9.10.000167
ORF1ab/nsp16143N143NaaTaaC22B0.000256
ORF1ab/nsp16143N143HAaTCaC22B.1.1600.000062
ORF1ab/nsp16143N143NaaTaaC22B.1.5960.000174
ORF1ab/nsp16143N143delAAT---22B.1.617.20.000008
ORF1ab/nsp16143N143NaaTaaC22B.1.6210.000177
ORF1ab/nsp16143N143HAaTCaC22B.4.80.142857
ORF1ab/nsp16143N143NaaTaaC22C.370.000232
ORF1ab/nsp16143N143KaaTaaA110.055556
ORF1ab/nsp16143N143HAaTCaC11A.23.10.000704
ORF1ab/nsp16143N143NaaTaaC11A.23.10.000704
ORF1ab/nsp16143N143NaaTaaC11AD.20.000219
ORF1ab/nsp16143N143del1Aat-at11All0
ORF1ab/nsp16143N143IaAtaTt11All0
ORF1ab/nsp16143N143MaATaTG11All0
ORF1ab/nsp16143N143DAatGat11AY.1030.000006
ORF1ab/nsp16143N143NaaTaaC11AY.1140.000231
ORF1ab/nsp16143N143delAAT---11AY.1200.000037
ORF1ab/nsp16143N143NaaTaaC11AY.130.000161
ORF1ab/nsp16143N143NaaTaaC11AY.140.000088
ORF1ab/nsp16143N143NaaTaaC11AY.160.00038
ORF1ab/nsp16143N143HAaTCaC11AY.260.000028
ORF1ab/nsp16143N143NaaTaaC11AY.270.000065
ORF1ab/nsp16143N143HAaTCaC11AY.30.00001
ORF1ab/nsp16143N143delAAT---11AY.330.000067
ORF1ab/nsp16143N143delAAT---11AY.430.000004
ORF1ab/nsp16143N143HAaTCaC11AY.440.000006
ORF1ab/nsp16143N143NaaTaaC11AY.460.000104
ORF1ab/nsp16143N143del2aATa--11AY.46.20.000635
ORF1ab/nsp16143N143DAatGat11AY.46.40.000165
ORF1ab/nsp16143N143HAaTCaC11AY.50.000021
ORF1ab/nsp16143N143NaaTaaC11AY.5.40.000277
ORF1ab/nsp16143N143NaaTaaC11AY.570.000656
ORF1ab/nsp16143N143HAaTCaC11AY.60.000041
ORF1ab/nsp16143N143NaaTaaC11AY.740.000116
ORF1ab/nsp16143N143NaaTaaC11AY.75.10.00018
ORF1ab/nsp16143N143NaaTaaC11AY.90.000068
ORF1ab/nsp16143N143NaaTaaC11AY.920.000287
ORF1ab/nsp16143N143NaaTaaC11AY.98.10.000048
ORF1ab/nsp16143N143DAatGat11B.10.000009
ORF1ab/nsp16143N143KaaTaaA11B.10.000009
ORF1ab/nsp16143N143IaAtaTt11B.10.000009
ORF1ab/nsp16143N143MaATaTG11B.10.000009
ORF1ab/nsp16143N143SaAtaGt11B.10.000009
ORF1ab/nsp16143N143HAaTCaC11B.10.000009
ORF1ab/nsp16143N143KaaTaaG11B.1.10.000018
ORF1ab/nsp16143N143DAatGat11B.1.10.000018
ORF1ab/nsp16143N143NaaTaaC11B.1.1.1640.005155
ORF1ab/nsp16143N143HAaTCaC11B.1.1.1640.005155
ORF1ab/nsp16143N143NaaTaaC11B.1.1.2160.00089
ORF1ab/nsp16143N143NaaTaaC11B.1.1.280.000311
ORF1ab/nsp16143N143NaaTaaC11B.1.1.3110.000358
ORF1ab/nsp16143N143HAaTCaC11B.1.1.3110.000358
ORF1ab/nsp16143N143delAAT---11B.1.1.3110.000358
ORF1ab/nsp16143N143del1Aat-at11B.1.1.70.000001
ORF1ab/nsp16143N143KaaTaaA11B.1.1.70.000001
ORF1ab/nsp16143N143delAAT---11B.1.1.700.000341
ORF1ab/nsp16143N143delAAT---11B.1.1770.000013
ORF1ab/nsp16143N143KaaTaaA11B.1.1770.000013
ORF1ab/nsp16143N143NaaTaaC11B.1.177.190.001431
ORF1ab/nsp16143N143HAaTCaC11B.1.177.190.001431
ORF1ab/nsp16143N143NaaTaaC11B.1.177.210.000076
ORF1ab/nsp16143N143YAatTat11B.1.177.330.001645
ORF1ab/nsp16143N143delAAT---11B.1.177.40.000211
ORF1ab/nsp16143N143delAAT---11B.1.177.540.000606
ORF1ab/nsp16143N143delAAT---11B.1.177.620.001192
ORF1ab/nsp16143N143delAAT---11B.1.177.70.000165
ORF1ab/nsp16143N143delAAT---11B.1.177.90.001332
ORF1ab/nsp16143N143YAatTat11B.1.20.000009
ORF1ab/nsp16143N143DAatGat11B.1.20.000009
ORF1ab/nsp16143N143NaaTaaC11B.1.2370.004975
ORF1ab/nsp16143N143NaaTaaC11B.1.2410.000812
ORF1ab/nsp16143N143delAAT---11B.1.2580.000067
ORF1ab/nsp16143N143NaaTaaC11B.1.258.30.001675
ORF1ab/nsp16143N143NaaTaaC11B.1.2700.005618
ORF1ab/nsp16143N143NaaTaaC11B.1.3510.00003
ORF1ab/nsp16143N143delAAT---11B.1.360.000146
ORF1ab/nsp16143N143NaaTaaC11B.1.400.10.015152
ORF1ab/nsp16143N143NaaTaaC11B.1.4270.00005
ORF1ab/nsp16143N143delAAT---11B.1.5250.000113
ORF1ab/nsp16143N143NaaTaaC11B.1.5260.000024
ORF1ab/nsp16143N143NaaTaaC11B.1.6050.005952
ORF1ab/nsp16143N143SaAtaGt11B.1.619.10.000641
ORF1ab/nsp16143N143delAAT---11B.1.6200.000946
ORF1ab/nsp16143N143delAAT---11B.340.013699
ORF1ab/nsp16143N143NaaTaaC11B.40.002208
ORF1ab/nsp16143N143DAatGat11D.20.000075
ORF1ab/nsp16143N143NaaTaaC11D.20.000075
ORF1ab/nsp16143N143KaaTaaG11P.1.10.000318
ORF1ab/nsp16143N143NaaTaaC11P.1.80.004785
ORF1ab/nsp16143N143NaaTaaC11Q.80.000165
ORF1ab/nsp16143N143del2AAt--t11U.30.003861

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.