CoV-GLUE | Mutations | Mutation
CoV-GLUE Mutation: ORF = ORF1ab/nsp15A1-B : Mut = V155V
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
| ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
| ORF1ab/nsp15A1-B | 155 | V155V | V6607V | syn | gtA | gtG | 2263 | 2158 | 0.953601 | 20083-20085 |
| ORF1ab/nsp15A1-B | 155 | V155V | V6607V | syn | gtA | gtT | 2263 | 92 | 0.040654 | 20083-20085 |
| ORF1ab/nsp15A1-B | 155 | V155V | V6607V | syn | gtA | gtC | 2263 | 13 | 0.00574459 | 20083-20085 |
Details of the mutation V155V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
| ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 2158 | 2263 | All | 0.000413 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtT | 92 | 2263 | All | 0.000018 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtC | 13 | 2263 | All | 0.000002 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1761 | 1761 | AY.62 | 0.76732 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 188 | 190 | B.1.617.2 | 0.000708 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtT | 2 | 190 | B.1.617.2 | 0.000008 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtT | 53 | 84 | AY.4 | 0.000082 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 30 | 84 | AY.4 | 0.000047 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtC | 1 | 84 | AY.4 | 0.000002 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 18 | 36 | B.1.1.7 | 0.000016 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtT | 17 | 36 | B.1.1.7 | 0.000015 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtC | 1 | 36 | B.1.1.7 | 0.000001 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 17 | 17 | AY.44 | 0.000103 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 17 | 17 | B.1.234 | 0.002243 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 14 | 14 | AY.16 | 0.005315 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 13 | 13 | AY.6 | 0.000535 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 10 | 10 | AY.5 | 0.000206 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 8 | 10 | B.1.2 | 0.00007 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtT | 1 | 10 | B.1.2 | 0.000009 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtC | 1 | 10 | B.1.2 | 0.000009 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtT | 7 | 7 | AY.4.2 | 0.000152 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtC | 4 | 5 | AY.23 | 0.000279 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 5 | AY.23 | 0.00007 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 4 | 4 | AY.20 | 0.000155 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 4 | 4 | AY.47 | 0.000124 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 3 | 3 | AY.103 | 0.000019 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 3 | 3 | AY.25 | 0.000018 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 3 | 3 | AY.26 | 0.000085 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 3 | 3 | AY.3 | 0.00003 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtT | 2 | 3 | AY.34 | 0.000194 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 3 | AY.34 | 0.000097 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 2 | 3 | B.1 | 0.000018 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtT | 1 | 3 | B.1 | 0.000009 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtT | 1 | 3 | B.1.1 | 0.000018 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtC | 1 | 3 | B.1.1 | 0.000018 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 3 | B.1.1 | 0.000018 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 3 | 3 | B.1.1.28 | 0.000934 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtC | 3 | 3 | B.1.526 | 0.000071 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 2 | 2 | AY.113 | 0.000285 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 2 | 2 | AY.37 | 0.000632 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 2 | 2 | AY.38 | 0.000999 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 2 | 2 | AY.39 | 0.000049 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 2 | 2 | AY.42 | 0.00008 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 2 | 2 | AY.43 | 0.000009 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 2 | 2 | AY.54 | 0.000191 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 2 | 2 | AY.75.1 | 0.000361 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtT | 2 | 2 | AY.98.1 | 0.000097 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtT | 2 | 2 | B.1.177.7 | 0.00033 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 2 | 2 | B.1.429 | 0.000047 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 2 | 2 | C.36 | 0.001821 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 2 | 2 | P.1 | 0.000032 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | AY.100 | 0.000046 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | AY.102 | 0.000027 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | AY.105 | 0.000643 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | AY.114 | 0.000231 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | AY.120.1 | 0.000321 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | AY.39.1 | 0.00004 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | AY.4.5 | 0.000107 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | AY.45 | 0.000122 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | AY.58 | 0.000907 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | AY.59 | 0.00053 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | AY.60 | 0.000938 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | AY.61 | 0.000105 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | AY.67 | 0.000464 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | AY.73 | 0.000665 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | AY.75 | 0.000056 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | AY.85 | 0.000427 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | AY.93 | 0.000273 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | B.1.1.311 | 0.000358 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtC | 1 | 1 | B.1.177 | 0.000013 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtT | 1 | 1 | B.1.177.44 | 0.000519 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtT | 1 | 1 | B.1.258 | 0.000067 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | B.1.258.17 | 0.000104 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | B.1.351 | 0.00003 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | B.1.351.2 | 0.000303 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | B.1.375 | 0.00082 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | B.1.427 | 0.00005 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | B.1.524 | 0.001406 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | B.1.538 | 0.008065 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | B.1.541 | 0.004425 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | B.1.595 | 0.000261 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | B.1.621 | 0.000089 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | B.1.637 | 0.000073 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | C.14 | 0.004329 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtT | 1 | 1 | P.1.10 | 0.000269 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtC | 1 | 1 | P.1.12 | 0.000484 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | P.1.14 | 0.000048 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtG | 1 | 1 | Q.8 | 0.000165 |
| ORF1ab/nsp15A1-B | 155 | V155V | gtA | gtT | 1 | 1 | R.1 | 0.00009 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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