CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp15A1-B : Mut = R257C

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp15A1-B257R257CR6709CnonsynCgtTgt424542430.99952920389-20391
ORF1ab/nsp15A1-B257R257CR6709CnonsynCgTTgC424520.00047114320389-20391

Details of the mutation R257C within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp15A1-B257R257CCgtTgt42434245All0.000812
ORF1ab/nsp15A1-B257R257CCgTTgC24245All0
ORF1ab/nsp15A1-B257R257CCgtTgt778778AU.10.98481
ORF1ab/nsp15A1-B257R257CCgtTgt601601AY.1030.003732
ORF1ab/nsp15A1-B257R257CCgtTgt562562B.1.617.20.002116
ORF1ab/nsp15A1-B257R257CCgtTgt241241AY.430.001068
ORF1ab/nsp15A1-B257R257CCgtTgt189189AY.40.000294
ORF1ab/nsp15A1-B257R257CCgtTgt164164AY.440.000998
ORF1ab/nsp15A1-B257R257CCgtTgt138138B.1.1.70.000124
ORF1ab/nsp15A1-B257R257CCgtTgt108108AY.50.00223
ORF1ab/nsp15A1-B257R257CCgtTgt107107B.1.2210.007601
ORF1ab/nsp15A1-B257R257CCgtTgt105105B.10.000962
ORF1ab/nsp15A1-B257R257CCgtTgt7272AY.30.000716
ORF1ab/nsp15A1-B257R257CCgtTgt7171B.1.2580.004725
ORF1ab/nsp15A1-B257R257CCgtTgt6363AY.4.20.001366
ORF1ab/nsp15A1-B257R257CCgtTgt5858B.1.1.3381
ORF1ab/nsp15A1-B257R257CCgtTgt5353B.1.20.000467
ORF1ab/nsp15A1-B257R257CCgtTgt5252A.23.10.03662
ORF1ab/nsp15A1-B257R257CCgtTgt5151AY.250.000307
ORF1ab/nsp15A1-B257R257CCgtTgt4545AY.330.003005
ORF1ab/nsp15A1-B257R257CCgtTgt4141B.1.10.000744
ORF1ab/nsp15A1-B257R257CCgtTgt4141B.1.160.80.052835
ORF1ab/nsp15A1-B257R257CCgtTgt3939AY.470.001213
ORF1ab/nsp15A1-B257R257CCgtTgt2727B.1.466.20.010563
ORF1ab/nsp15A1-B257R257CCgtTgt2525B.1.1.5190.000993
ORF1ab/nsp15A1-B257R257CCgtTgt2222AY.200.000855
ORF1ab/nsp15A1-B257R257CCgtTgt2222AY.340.002133
ORF1ab/nsp15A1-B257R257CCgtTgt2121AY.120.006637
ORF1ab/nsp15A1-B257R257CCgtTgt2121AY.750.001176
ORF1ab/nsp15A1-B257R257CCgtTgt2020AY.1020.00053
ORF1ab/nsp15A1-B257R257CCgtTgt2020AY.46.60.001444
ORF1ab/nsp15A1-B257R257CCgtTgt1919B.1.1.3690.008478
ORF1ab/nsp15A1-B257R257CCgtTgt1717B.1.1770.000224
ORF1ab/nsp15A1-B257R257CCgtTgt1616A.2.40.053872
ORF1ab/nsp15A1-B257R257CCgtTgt1616AY.1140.003698
ORF1ab/nsp15A1-B257R257CCgtTgt1616AY.390.000395
ORF1ab/nsp15A1-B257R257CCgtTgt1616B.1.5610.006352
ORF1ab/nsp15A1-B257R257CCgtTgt1313AY.260.000368
ORF1ab/nsp15A1-B257R257CCgtTgt1313B.1.1.2220.002652
ORF1ab/nsp15A1-B257R257CCgtTgt1111B.1.1600.000343
ORF1ab/nsp15A1-B257R257CCgtTgt99AY.1200.000335
ORF1ab/nsp15A1-B257R257CCgtTgt99AY.460.000937
ORF1ab/nsp15A1-B257R257CCgtTgt99B.1.3510.000268
ORF1ab/nsp15A1-B257R257CCgtTgt88AY.290.000126
ORF1ab/nsp15A1-B257R257CCgtTgt88AY.3.10.000682
ORF1ab/nsp15A1-B257R257CCgtTgt77AY.46.40.001152
ORF1ab/nsp15A1-B257R257CCgtTgt77B.1.1.1530.007667
ORF1ab/nsp15A1-B257R257CCgtTgt66AY.230.000418
ORF1ab/nsp15A1-B257R257CCgtTgt66B.1.177.570.001686
ORF1ab/nsp15A1-B257R257CCgtTgt66B.1.4590.02449
ORF1ab/nsp15A1-B257R257CCgtTgt66Q.40.002729
ORF1ab/nsp15A1-B257R257CCgtTgt55AY.450.000608
ORF1ab/nsp15A1-B257R257CCgtTgt55AY.60.000206
ORF1ab/nsp15A1-B257R257CCgtTgt55B.1.2180.025773
ORF1ab/nsp15A1-B257R257CCgtTgt44AY.420.000161
ORF1ab/nsp15A1-B257R257CCgtTgt44AY.90.00027
ORF1ab/nsp15A1-B257R257CCgtTgt44AY.9.20.000147
ORF1ab/nsp15A1-B257R257CCgtTgt44AY.98.10.000194
ORF1ab/nsp15A1-B257R257CCgtTgt44AY.99.20.000369
ORF1ab/nsp15A1-B257R257CCgtTgt44B.1.1.2140.000222
ORF1ab/nsp15A1-B257R257CCgtTgt44B.1.177.160.002658
ORF1ab/nsp15A1-B257R257CCgtTgt44B.1.177.330.006579
ORF1ab/nsp15A1-B257R257CCgtTgt44B.1.177.770.002905
ORF1ab/nsp15A1-B257R257CCgtTgt44B.1.2600.013378
ORF1ab/nsp15A1-B257R257CCgtTgt44C.370.000464
ORF1ab/nsp15A1-B257R257CCgtTgt44P.10.000063
ORF1ab/nsp15A1-B257R257CCgtTgt44P.1.140.000191
ORF1ab/nsp15A1-B257R257CCgtTgt44R.10.00036
ORF1ab/nsp15A1-B257R257CCgtTgt33AY.1000.000138
ORF1ab/nsp15A1-B257R257CCgtTgt33AY.1060.001005
ORF1ab/nsp15A1-B257R257CCgtTgt33AY.1130.000427
ORF1ab/nsp15A1-B257R257CCgtTgt33AY.1170.000254
ORF1ab/nsp15A1-B257R257CCgtTgt33AY.1190.000106
ORF1ab/nsp15A1-B257R257CCgtTgt33AY.5.30.001012
ORF1ab/nsp15A1-B257R257CCgtTgt33AY.670.001393
ORF1ab/nsp15A1-B257R257CCgtTgt33AY.920.000862
ORF1ab/nsp15A1-B257R257CCgtTgt33B.1.1.10.00098
ORF1ab/nsp15A1-B257R257CCgtTgt33B.1.1390.002199
ORF1ab/nsp15A1-B257R257CCgtTgt33B.1.177.560.002003
ORF1ab/nsp15A1-B257R257CCgtTgt33B.1.177.810.000568
ORF1ab/nsp15A1-B257R257CCgtTgt33B.1.2340.000396
ORF1ab/nsp15A1-B257R257CCgtTgt33B.1.4620.021739
ORF1ab/nsp15A1-B257R257CCgtTgt33B.1.5960.000261
ORF1ab/nsp15A1-B257R257CCgtTgt33D.20.000225
ORF1ab/nsp15A1-B257R257CCgtTgt33P.1.70.000958
ORF1ab/nsp15A1-B257R257CCgTTgC220.111111
ORF1ab/nsp15A1-B257R257CCgtTgt22AY.1210.000271
ORF1ab/nsp15A1-B257R257CCgtTgt22AY.190.002281
ORF1ab/nsp15A1-B257R257CCgtTgt22AY.23.10.000835
ORF1ab/nsp15A1-B257R257CCgtTgt22AY.39.10.000079
ORF1ab/nsp15A1-B257R257CCgtTgt22AY.4.50.000215
ORF1ab/nsp15A1-B257R257CCgtTgt22AY.5.40.000553
ORF1ab/nsp15A1-B257R257CCgtTgt22AY.550.001835
ORF1ab/nsp15A1-B257R257CCgtTgt22AY.740.000231
ORF1ab/nsp15A1-B257R257CCgtTgt22AY.850.000854
ORF1ab/nsp15A1-B257R257CCgtTgt22AY.860.00166
ORF1ab/nsp15A1-B257R257CCgtTgt22AY.9.10.000167
ORF1ab/nsp15A1-B257R257CCgtTgt22B.1.1.2200.003717
ORF1ab/nsp15A1-B257R257CCgtTgt22B.1.1.280.000622
ORF1ab/nsp15A1-B257R257CCgtTgt22B.1.1.2970.004474
ORF1ab/nsp15A1-B257R257CCgtTgt22B.1.1.3680.006173
ORF1ab/nsp15A1-B257R257CCgtTgt22B.1.1.390.001019
ORF1ab/nsp15A1-B257R257CCgtTgt22B.1.1.4160.00181
ORF1ab/nsp15A1-B257R257CCgtTgt22B.1.1.990.047619
ORF1ab/nsp15A1-B257R257CCgtTgt22B.1.177.70.00033
ORF1ab/nsp15A1-B257R257CCgtTgt22B.1.2320.001075
ORF1ab/nsp15A1-B257R257CCgtTgt22B.1.3960.001411
ORF1ab/nsp15A1-B257R257CCgtTgt22B.1.4090.001563
ORF1ab/nsp15A1-B257R257CCgtTgt22B.1.4290.000047
ORF1ab/nsp15A1-B257R257CCgtTgt22B.1.438.10.000215
ORF1ab/nsp15A1-B257R257CCgtTgt22B.1.5170.000854
ORF1ab/nsp15A1-B257R257CCgtTgt22B.1.5640.000852
ORF1ab/nsp15A1-B257R257CCgtTgt22B.1.5950.000522
ORF1ab/nsp15A1-B257R257CCgtTgt22B.1.6090.000959
ORF1ab/nsp15A1-B257R257CCgtTgt22B.1.6180.008065
ORF1ab/nsp15A1-B257R257CCgtTgt22B.1.9.50.011364
ORF1ab/nsp15A1-B257R257CCgtTgt22B.400.000729
ORF1ab/nsp15A1-B257R257CCgtTgt22N.40.008511
ORF1ab/nsp15A1-B257R257CCgtTgt11A0.000387
ORF1ab/nsp15A1-B257R257CCgtTgt11A.10.000282
ORF1ab/nsp15A1-B257R257CCgtTgt11A.20.000662
ORF1ab/nsp15A1-B257R257CCgtTgt11A.2.50.000499
ORF1ab/nsp15A1-B257R257CCgtTgt11A.30.002096
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.1010.00049
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.1160.000287
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.130.000161
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.140.000088
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.160.00038
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.16.10.00047
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.210.001898
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.240.000431
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.270.000065
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.350.000233
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.370.000316
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.380.000499
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.46.10.001027
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.46.50.000198
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.520.000814
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.580.000907
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.610.000105
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.710.000475
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.75.10.00018
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.820.001357
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.950.000761
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.960.002075
ORF1ab/nsp15A1-B257R257CCgtTgt11AY.980.000079
ORF1ab/nsp15A1-B257R257CCgtTgt11AZ.50.003509
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.1.1980.001468
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.1.260.005236
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.1.2650.003155
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.1.2840.000107
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.1.2880.001916
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.1.3170.000412
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.1.3230.014085
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.1.3910.008547
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.1.4340.000349
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.1.4480.002033
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.1.4640.001473
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.1.500.000679
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.1.5230.001563
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.1470.000756
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.1490.003425
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.177.120.000152
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.177.230.003236
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.177.430.001477
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.177.450.000381
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.177.600.000218
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.177.80.000752
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.177.820.000477
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.177.860.000183
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.177.880.012346
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.220.001318
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.2220.001692
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.258.110.000396
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.258.170.000104
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.3110.000275
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.360.000146
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.36.290.000517
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.36.350.002604
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.3690.000285
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.3710.001122
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.4000.000429
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.4690.00361
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.5230.002451
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.5240.001406
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.5260.000024
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.5270.003704
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.5600.00463
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.5820.000491
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.5880.00091
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.617.10.000129
ORF1ab/nsp15A1-B257R257CCgtTgt11B.1.6370.000073
ORF1ab/nsp15A1-B257R257CCgtTgt11B.30.000831
ORF1ab/nsp15A1-B257R257CCgtTgt11B.390.002331
ORF1ab/nsp15A1-B257R257CCgtTgt11B.6.60.000889
ORF1ab/nsp15A1-B257R257CCgtTgt11C.260.007353
ORF1ab/nsp15A1-B257R257CCgtTgt11C.310.017857
ORF1ab/nsp15A1-B257R257CCgtTgt11N.50.001767
ORF1ab/nsp15A1-B257R257CCgtTgt11P.1.170.000162
ORF1ab/nsp15A1-B257R257CCgtTgt11P.20.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.