CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp15A1-B : Mut = A217V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp15A1-B217A217VA6669VnonsyngCtgTt260926070.99923320269-20271
ORF1ab/nsp15A1-B217A217VA6669VnonsyngCTgTC260920.00076657720269-20271

Details of the mutation A217V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp15A1-B217A217VgCtgTt26072609All0.000499
ORF1ab/nsp15A1-B217A217VgCTgTC22609All0
ORF1ab/nsp15A1-B217A217VgCtgTt657657AP.10.986486
ORF1ab/nsp15A1-B217A217VgCtgTt482482B.1.1.70.000431
ORF1ab/nsp15A1-B217A217VgCtgTt387387AY.50.007991
ORF1ab/nsp15A1-B217A217VgCtgTt318318B.230.929825
ORF1ab/nsp15A1-B217A217VgCtgTt8181AY.1030.000503
ORF1ab/nsp15A1-B217A217VgCtgTt5959AY.46.40.009706
ORF1ab/nsp15A1-B217A217VgCtgTt5050AY.40.000078
ORF1ab/nsp15A1-B217A217VgCtgTt4343B.10.000394
ORF1ab/nsp15A1-B217A217VgCtgTt4243B.1.617.20.000158
ORF1ab/nsp15A1-B217A217VgCTgTC143B.1.617.20.000004
ORF1ab/nsp15A1-B217A217VgCtgTt3434B.1.1.700.011596
ORF1ab/nsp15A1-B217A217VgCtgTt3434B.1.20.000299
ORF1ab/nsp15A1-B217A217VgCtgTt3434P.10.000536
ORF1ab/nsp15A1-B217A217VgCtgTt3131AY.250.000186
ORF1ab/nsp15A1-B217A217VgCtgTt2929B.1.1600.000904
ORF1ab/nsp15A1-B217A217VgCtgTt2525B.1.1.10.008167
ORF1ab/nsp15A1-B217A217VgCtgTt2222AY.270.001424
ORF1ab/nsp15A1-B217A217VgCtgTt1919AY.470.000591
ORF1ab/nsp15A1-B217A217VgCtgTt1717AY.430.000075
ORF1ab/nsp15A1-B217A217VgCtgTt1717B.1.4290.0004
ORF1ab/nsp15A1-B217A217VgCtgTt1616AY.390.000395
ORF1ab/nsp15A1-B217A217VgCtgTt1515B.1.10.000272
ORF1ab/nsp15A1-B217A217VgCtgTt1314AY.440.000079
ORF1ab/nsp15A1-B217A217VgCTgTC114AY.440.000006
ORF1ab/nsp15A1-B217A217VgCtgTt1414B.1.1.5190.000556
ORF1ab/nsp15A1-B217A217VgCtgTt1212AY.260.00034
ORF1ab/nsp15A1-B217A217VgCtgTt1212AY.290.000189
ORF1ab/nsp15A1-B217A217VgCtgTt88B.1.1770.000105
ORF1ab/nsp15A1-B217A217VgCtgTt77B0.000895
ORF1ab/nsp15A1-B217A217VgCtgTt77B.1.6370.000512
ORF1ab/nsp15A1-B217A217VgCtgTt66AY.4.20.00013
ORF1ab/nsp15A1-B217A217VgCtgTt55B.1.2580.000333
ORF1ab/nsp15A1-B217A217VgCtgTt55R.10.00045
ORF1ab/nsp15A1-B217A217VgCtgTt44AY.4.40.001637
ORF1ab/nsp15A1-B217A217VgCtgTt44AY.590.002119
ORF1ab/nsp15A1-B217A217VgCtgTt44B.1.5260.000094
ORF1ab/nsp15A1-B217A217VgCtgTt33AY.1190.000106
ORF1ab/nsp15A1-B217A217VgCtgTt33AY.130.000483
ORF1ab/nsp15A1-B217A217VgCtgTt33AY.200.000117
ORF1ab/nsp15A1-B217A217VgCtgTt33AY.30.00003
ORF1ab/nsp15A1-B217A217VgCtgTt33AY.300.001187
ORF1ab/nsp15A1-B217A217VgCtgTt33B.1.3400.012876
ORF1ab/nsp15A1-B217A217VgCtgTt33P.20.00056
ORF1ab/nsp15A1-B217A217VgCtgTt22AY.1020.000053
ORF1ab/nsp15A1-B217A217VgCtgTt22AY.1170.000169
ORF1ab/nsp15A1-B217A217VgCtgTt22AY.1200.000074
ORF1ab/nsp15A1-B217A217VgCtgTt22AY.3.10.000171
ORF1ab/nsp15A1-B217A217VgCtgTt22AY.330.000134
ORF1ab/nsp15A1-B217A217VgCtgTt22AY.610.00021
ORF1ab/nsp15A1-B217A217VgCtgTt22AY.900.001369
ORF1ab/nsp15A1-B217A217VgCtgTt22B.1.1.250.001137
ORF1ab/nsp15A1-B217A217VgCtgTt22B.1.177.750.002081
ORF1ab/nsp15A1-B217A217VgCtgTt22B.1.2210.000142
ORF1ab/nsp15A1-B217A217VgCtgTt22B.1.2340.000264
ORF1ab/nsp15A1-B217A217VgCtgTt22B.1.3150.012121
ORF1ab/nsp15A1-B217A217VgCtgTt22B.1.360.000292
ORF1ab/nsp15A1-B217A217VgCtgTt22B.1.466.20.000782
ORF1ab/nsp15A1-B217A217VgCtgTt22B.1.6210.000177
ORF1ab/nsp15A1-B217A217VgCtgTt22B.1.6280.000705
ORF1ab/nsp15A1-B217A217VgCtgTt22C.10.004785
ORF1ab/nsp15A1-B217A217VgCtgTt22C.37.10.005236
ORF1ab/nsp15A1-B217A217VgCtgTt22P.1.100.000539
ORF1ab/nsp15A1-B217A217VgCtgTt11AD.20.000219
ORF1ab/nsp15A1-B217A217VgCtgTt11AY.1000.000046
ORF1ab/nsp15A1-B217A217VgCtgTt11AY.120.10.000321
ORF1ab/nsp15A1-B217A217VgCtgTt11AY.160.00038
ORF1ab/nsp15A1-B217A217VgCtgTt11AY.190.00114
ORF1ab/nsp15A1-B217A217VgCtgTt11AY.340.000097
ORF1ab/nsp15A1-B217A217VgCtgTt11AY.39.10.00004
ORF1ab/nsp15A1-B217A217VgCtgTt11AY.4.50.000107
ORF1ab/nsp15A1-B217A217VgCtgTt11AY.420.00004
ORF1ab/nsp15A1-B217A217VgCtgTt11AY.450.000122
ORF1ab/nsp15A1-B217A217VgCtgTt11AY.5.30.000337
ORF1ab/nsp15A1-B217A217VgCtgTt11AY.580.000907
ORF1ab/nsp15A1-B217A217VgCtgTt11AY.60.000041
ORF1ab/nsp15A1-B217A217VgCtgTt11AY.620.000436
ORF1ab/nsp15A1-B217A217VgCtgTt11AY.9.10.000084
ORF1ab/nsp15A1-B217A217VgCtgTt11AY.980.000079
ORF1ab/nsp15A1-B217A217VgCtgTt11AY.98.10.000048
ORF1ab/nsp15A1-B217A217VgCtgTt11AY.99.20.000092
ORF1ab/nsp15A1-B217A217VgCtgTt11B.1.1.100.001115
ORF1ab/nsp15A1-B217A217VgCtgTt11B.1.1.3060.000438
ORF1ab/nsp15A1-B217A217VgCtgTt11B.1.1.370.000193
ORF1ab/nsp15A1-B217A217VgCtgTt11B.1.1.630.000386
ORF1ab/nsp15A1-B217A217VgCtgTt11B.1.110.30.000718
ORF1ab/nsp15A1-B217A217VgCtgTt11B.1.160.310.008065
ORF1ab/nsp15A1-B217A217VgCtgTt11B.1.177.280.007407
ORF1ab/nsp15A1-B217A217VgCtgTt11B.1.177.360.016129
ORF1ab/nsp15A1-B217A217VgCtgTt11B.1.177.600.000218
ORF1ab/nsp15A1-B217A217VgCtgTt11B.1.1900.01
ORF1ab/nsp15A1-B217A217VgCtgTt11B.1.3110.000275
ORF1ab/nsp15A1-B217A217VgCtgTt11B.1.3510.00003
ORF1ab/nsp15A1-B217A217VgCtgTt11B.1.3890.001002
ORF1ab/nsp15A1-B217A217VgCtgTt11B.1.4160.001269
ORF1ab/nsp15A1-B217A217VgCtgTt11B.1.5960.000087
ORF1ab/nsp15A1-B217A217VgCtgTt11B.1.617.10.000129
ORF1ab/nsp15A1-B217A217VgCtgTt11P.1.170.000162

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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