CoV-GLUE | Mutations | Mutation
CoV-GLUE Mutation: ORF = ORF1ab/nsp15A1-B : CodonNum = 206 & Codon = aTg
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
| ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
| ORF1ab/nsp15A1-B | 206 | R206M | R6658M | nonsyn | aGg | aTg | 630 | 630 | 1 | 20236-20238 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
| ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 630 | 630 | All | 0.00012 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 102 | 102 | AY.25 | 0.000614 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 89 | 89 | B.1.177 | 0.001172 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 65 | 65 | AY.20 | 0.002526 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 38 | 38 | B.1.1.7 | 0.000034 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 35 | 35 | AY.4 | 0.000054 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 32 | 32 | B.1.2 | 0.000282 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 26 | 26 | B.1.160.16 | 0.024164 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 21 | 21 | AY.29 | 0.000331 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 18 | 18 | AY.44 | 0.00011 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 18 | 18 | B.1.243 | 0.001253 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 17 | 17 | B.1.617.2 | 0.000064 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 9 | 9 | AY.103 | 0.000056 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 9 | 9 | AY.26 | 0.000255 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 9 | 9 | AY.43 | 0.00004 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 9 | 9 | D.2 | 0.000675 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 7 | 7 | AY.3 | 0.00007 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 7 | 7 | B.1 | 0.000064 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 7 | 7 | B.1.1.317 | 0.002882 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 7 | 7 | B.1.1.519 | 0.000278 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 6 | 6 | AY.121 | 0.000812 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 5 | 5 | AE.8 | 0.002445 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 5 | 5 | P.1 | 0.000079 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 5 | 5 | P.1.1 | 0.001588 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 3 | 3 | AY.116 | 0.00086 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 3 | 3 | AY.47 | 0.000093 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 3 | 3 | AY.5 | 0.000062 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 3 | 3 | B.1.1 | 0.000054 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 3 | 3 | B.1.396 | 0.002117 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 3 | 3 | B.1.429 | 0.000071 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 2 | 2 | AY.100 | 0.000092 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 2 | 2 | AY.102 | 0.000053 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 2 | 2 | AY.117 | 0.000169 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 2 | 2 | AY.54 | 0.000191 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 2 | 2 | AY.75.1 | 0.000361 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 2 | 2 | B.1.1.318 | 0.000604 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 2 | 2 | B.1.1.462 | 0.017241 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 2 | 2 | B.1.258.17 | 0.000208 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 2 | 2 | B.1.596 | 0.000174 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 2 | 2 | B.1.617.1 | 0.000258 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | A | 0.000387 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | A.1 | 0.000282 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | AY.111 | 0.000183 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | AY.118 | 0.000063 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | AY.119 | 0.000035 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | AY.3.1 | 0.000085 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | AY.36 | 0.000148 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | AY.37 | 0.000316 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | AY.39 | 0.000025 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | AY.41 | 0.000294 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | AY.45 | 0.000122 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | AY.46 | 0.000104 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | AY.46.4 | 0.000165 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | AY.60 | 0.000938 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | AY.82 | 0.001357 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | AY.84 | 0.000437 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | AY.9.2 | 0.000037 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | AY.92 | 0.000287 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | AY.98.1 | 0.000048 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.1.118 | 0.010204 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.1.144 | 0.028571 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.1.181 | 0.004545 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.1.306 | 0.000438 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.103 | 0.019231 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.118 | 0.006711 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.160 | 0.000031 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.177.86 | 0.000183 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.214.2 | 0.0006 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.221 | 0.000071 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.232 | 0.000537 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.234 | 0.000132 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.258 | 0.000067 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.301 | 0.005917 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.336 | 0.002439 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.351 | 0.00003 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.36.39 | 0.002217 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.361 | 0.001289 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.428 | 0.00102 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.525 | 0.000113 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.546 | 0.003704 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.1.551 | 0.00129 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.3.1 | 0.001658 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.55 | 0.00295 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | B.6 | 0.00091 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | P.1.14 | 0.000048 |
| ORF1ab/nsp15A1-B | 206 | R206M | aGg | aTg | 1 | 1 | Q.3 | 0.000145 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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