CoV-GLUE | Mutations | Mutation
CoV-GLUE Mutation: ORF = ORF1ab/nsp14A2-B : Mut = V263F
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
| ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
| ORF1ab/nsp14A2-B | 263 | V263F | V6188F | nonsyn | Gtc | Ttc | 940 | 940 | 1 | 18826-18828 |
Details of the mutation V263F within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
| ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 940 | 940 | All | 0.00018 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 187 | 187 | AY.4 | 0.000291 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 86 | 86 | AY.103 | 0.000534 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 79 | 79 | B.1.1.7 | 0.000071 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 73 | 73 | AY.25 | 0.000439 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 49 | 49 | AY.43 | 0.000217 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 49 | 49 | B.1.160.18 | 0.357664 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 35 | 35 | B.1.617.2 | 0.000132 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 29 | 29 | AY.9.2 | 0.001065 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 22 | 22 | B.1.1.63 | 0.008488 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 20 | 20 | B.1.177 | 0.000263 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 18 | 18 | AY.102 | 0.000477 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 17 | 17 | B.1 | 0.000156 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 16 | 16 | AY.44 | 0.000097 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 15 | 15 | B.1.1 | 0.000272 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 14 | 14 | B.1.1.50 | 0.009504 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 12 | 12 | AY.116 | 0.003441 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 10 | 10 | B.1.160 | 0.000312 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 10 | 10 | P.1.8 | 0.047847 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 9 | 9 | B.1.2 | 0.000079 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 9 | 9 | P.1 | 0.000142 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 7 | 7 | AY.5 | 0.000145 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 7 | 7 | B.1.1.189 | 0.01059 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 6 | 6 | B.1.1.519 | 0.000238 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 5 | 5 | AY.61 | 0.000524 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 5 | 5 | AY.99.2 | 0.000461 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 4 | 4 | AY.39 | 0.000099 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 4 | 4 | AY.45 | 0.000487 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 4 | 4 | AY.7.1 | 0.000451 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 4 | 4 | AY.98 | 0.000316 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 4 | 4 | B.1.1.214 | 0.000222 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 4 | 4 | B.1.311 | 0.001098 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 4 | 4 | B.1.525 | 0.000453 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 3 | 3 | AY.121 | 0.000406 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 3 | 3 | AY.14 | 0.000264 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 3 | 3 | B.1.1.325 | 0.076923 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 3 | 3 | B.1.1.416 | 0.002715 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 3 | 3 | B.1.221 | 0.000213 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 3 | 3 | B.1.351 | 0.000089 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 3 | 3 | B.1.36 | 0.000438 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 3 | 3 | B.1.595 | 0.000783 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 3 | 3 | P.1.7 | 0.000958 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | A.5 | 0.003846 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | AY.119 | 0.000071 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | AY.20 | 0.000078 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | AY.23 | 0.000139 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | AY.26 | 0.000057 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | AY.3 | 0.00002 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | AY.4.5 | 0.000215 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | AY.42 | 0.00008 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | AY.46 | 0.000208 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | AY.54 | 0.000191 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | B.1.1.222 | 0.000408 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | B.1.1.258 | 0.006515 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | B.1.1.348 | 0.001592 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | B.1.1.370 | 0.025316 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | B.1.1.373 | 0.047619 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | B.1.177.69 | 0.002967 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | B.1.258 | 0.000133 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | B.1.258.17 | 0.000208 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | B.1.36.7 | 0.008 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | B.1.427 | 0.000101 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | B.1.561 | 0.000794 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | B.1.628 | 0.000705 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | P.1.14 | 0.000096 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | Q.8 | 0.00033 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | R.1 | 0.00018 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 2 | 2 | R.2 | 0.028986 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | A.23.1 | 0.000704 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | AY.105 | 0.000643 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | AY.106 | 0.000335 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | AY.113 | 0.000142 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | AY.117 | 0.000085 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | AY.120 | 0.000037 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | AY.24 | 0.000431 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | AY.27 | 0.000065 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | AY.3.1 | 0.000085 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | AY.46.5 | 0.000198 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | AY.46.6 | 0.000072 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | AY.51 | 0.000909 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | AY.59 | 0.00053 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | AY.64 | 0.000595 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | AY.67 | 0.000464 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | AY.69 | 0.000187 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | AY.9.1 | 0.000084 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.1.118 | 0.010204 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.1.231 | 0.003096 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.1.306 | 0.000438 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.1.344 | 0.010753 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.1.365 | 0.005587 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.1.372 | 0.000689 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.1.432 | 0.001266 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.1.434 | 0.000349 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.160.14 | 0.002119 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.177.19 | 0.001431 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.177.57 | 0.000281 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.234 | 0.000132 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.243 | 0.00007 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.349 | 0.000715 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.36.29 | 0.000517 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.400 | 0.000429 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.429 | 0.000024 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.438.1 | 0.000107 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.480 | 0.002488 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.517 | 0.000427 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.609 | 0.000479 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | B.1.627 | 0.00202 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | C.14 | 0.004329 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | C.8 | 0.004464 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | D.2 | 0.000075 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | L.3 | 0.003546 |
| ORF1ab/nsp14A2-B | 263 | V263F | Gtc | Ttc | 1 | 1 | P.1.17 | 0.000162 |
 |
 |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
|