CoV-GLUE | Mutations | Mutation
CoV-GLUE Mutation: ORF = ORF1ab/nsp14A2-B : Mut = V236F
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
| ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
| ORF1ab/nsp14A2-B | 236 | V236F | V6161F | nonsyn | Gtc | Ttc | 633 | 626 | 0.988942 | 18745-18747 |
| ORF1ab/nsp14A2-B | 236 | V236F | V6161F | nonsyn | GtC | TtT | 633 | 7 | 0.0110585 | 18745-18747 |
Details of the mutation V236F within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
| ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 626 | 633 | All | 0.00012 |
| ORF1ab/nsp14A2-B | 236 | V236F | GtC | TtT | 7 | 633 | All | 0.000001 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 266 | 272 | B.1.1.7 | 0.000238 |
| ORF1ab/nsp14A2-B | 236 | V236F | GtC | TtT | 6 | 272 | B.1.1.7 | 0.000005 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 36 | 36 | B.1.160.8 | 0.046392 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 32 | 32 | AY.43 | 0.000142 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 24 | 24 | B.1 | 0.00022 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 20 | 20 | AY.4 | 0.000031 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 18 | 19 | B.1.2 | 0.000158 |
| ORF1ab/nsp14A2-B | 236 | V236F | GtC | TtT | 1 | 19 | B.1.2 | 0.000009 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 17 | 17 | AY.103 | 0.000106 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 14 | 14 | B.1.160 | 0.000437 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 11 | 11 | B.1.516 | 0.021526 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 10 | 10 | AY.25 | 0.00006 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 9 | 9 | B.1.1 | 0.000163 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 9 | 9 | B.1.409 | 0.007031 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 9 | 9 | B.1.617.1 | 0.001161 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 7 | 7 | AY.4.2 | 0.000152 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 7 | 7 | B.1.177 | 0.000092 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 7 | 7 | B.1.427 | 0.000353 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 7 | 7 | B.1.429 | 0.000165 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 7 | 7 | B.1.526 | 0.000165 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 6 | 6 | AY.7 | 0.001176 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 5 | 5 | AY.39 | 0.000124 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 5 | 5 | AY.6 | 0.000206 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 5 | 5 | AY.9.2 | 0.000184 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 4 | 4 | B.1.617.2 | 0.000015 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 3 | 3 | B.1.1.214 | 0.000166 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 3 | 3 | B.1.396 | 0.002117 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 3 | 3 | B.1.600 | 0.017544 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 3 | 3 | D.2 | 0.000225 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 3 | 3 | P.1 | 0.000047 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 3 | 3 | P.2 | 0.00056 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 3 | 3 | Q.8 | 0.000495 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 2 | 2 | 0.111111 | |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 2 | 2 | AD.2 | 0.000438 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 2 | 2 | AY.29 | 0.000032 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 2 | 2 | AY.3 | 0.00002 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 2 | 2 | AY.98.1 | 0.000097 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 2 | 2 | B.1.1.434 | 0.000697 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 2 | 2 | B.1.1.519 | 0.000079 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 2 | 2 | B.1.210 | 0.004264 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 2 | 2 | B.1.243 | 0.000139 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 2 | 2 | B.1.258 | 0.000133 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 2 | 2 | P.1.14 | 0.000096 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 2 | 2 | W.2 | 0.009662 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | A | 0.000387 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | AU.1 | 0.001266 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | AY.100 | 0.000046 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | AY.102 | 0.000027 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | AY.118 | 0.000063 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | AY.119 | 0.000035 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | AY.30 | 0.000396 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | AY.33 | 0.000067 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | AY.34 | 0.000097 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | AY.42 | 0.00004 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | AY.44 | 0.000006 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | AY.5 | 0.000021 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | AY.64 | 0.000595 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | AY.75.1 | 0.00018 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.1.1 | 0.000327 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.1.121 | 0.002427 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.1.161 | 0.003534 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.1.164 | 0.005155 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.1.204 | 0.00304 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.1.222 | 0.000204 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.1.241 | 0.00207 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.1.26 | 0.005236 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.1.294 | 0.001266 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.1.306 | 0.000438 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.1.326 | 0.001761 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.177.23 | 0.003236 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.177.4 | 0.000211 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.177.56 | 0.000668 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.258.17 | 0.000104 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.351 | 0.00003 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.36 | 0.000146 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.361 | 0.001289 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.367 | 0.000792 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.389 | 0.001002 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.459 | 0.004082 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.525 | 0.000113 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.1.9.4 | 0.006135 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.11 | 0.005128 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | B.40 | 0.000364 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | C.23 | 0.005814 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | C.37 | 0.000116 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | P.1.17 | 0.000162 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | Q.1 | 0.000126 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | Q.3 | 0.000145 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | Q.7 | 0.001111 |
| ORF1ab/nsp14A2-B | 236 | V236F | Gtc | Ttc | 1 | 1 | R.1 | 0.00009 |
 |
 |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
|