CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp14A2-B : Mut = S369F

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF1ab/nsp14A2-B	369	S369F	S6294F	nonsyn	tCt	tTt	1815	1815	1	19144-19146

Details of the mutation S369F within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1815	1815	All	0.000347
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	339	339	B.1.1.7	0.000303
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	148	148	AY.4	0.00023
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	128	128	B.1.258	0.008518
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	107	107	AY.103	0.000664
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	73	73	B.1.258.17	0.00759
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	50	50	AY.43	0.000222
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	50	50	B.1.426	0.050454
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	49	49	B.1.177	0.000645
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	43	43	B.1.2	0.000379
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	39	39	B.1.508	1
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	37	37	AY.6	0.001522
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	37	37	B.1	0.000339
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	36	36	B.1.617.2	0.000136
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	34	34	B.1.1	0.000617
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	31	31	AY.46.5	0.006151
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	31	31	B.1.177.81	0.005869
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	29	29	B.1.1.519	0.001152
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	25	25	P.1	0.000394
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	25	25	W.2	0.120773
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	24	24	AY.25	0.000144
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	21	21	AY.44	0.000128
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	20	20	AY.5	0.000413
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	19	19	B.1.177.75	0.019771
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	14	14	B.1.160	0.000437
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	13	13	AY.29	0.000205
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	12	12	B.1.1.326	0.021127
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	11	11	AY.4.2	0.000239
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	11	11	B.1.36.18	0.004622
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	10	10	AY.20	0.000389
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	10	10	B.1.221	0.00071
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	10	10	B.1.453	0.032362
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	10	10	B.1.526	0.000235
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	9	9	AY.34	0.000873
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	8	8	AY.9.2	0.000294
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	8	8	B.1.177.21	0.000612
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	8	8	B.1.311	0.002197
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	8	8	B.1.617.1	0.001032
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	8	8	P.1.7	0.002554
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	7	7	AY.47	0.000218
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	6	6	AY.102	0.000159
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	6	6	AY.41	0.001764
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	6	6	AZ.2	0.004926
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	6	6	B.1.351	0.000178
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	6	6	B.1.429	0.000141
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	6	6	B.1.621	0.000531
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	6	6	P.2	0.00112
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	5	5	AY.14	0.00044
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	5	5	AY.3	0.00005
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	5	5	AY.42	0.000201
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	5	5	B.1.177.4	0.001055
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	5	5	B.1.470	0.007022
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	4	4	A.28	0.010582
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	4	4	AY.100	0.000184
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	4	4	AY.118	0.000251
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	4	4	AY.46.6	0.000289
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	4	4	AY.62	0.001743
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	4	4	B.1.1.204	0.012158
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	4	4	B.1.1.214	0.000222
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	4	4	B.1.1.222	0.000816
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	4	4	B.1.1.434	0.001394
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	4	4	B.1.177.82	0.001909
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	4	4	B.1.243	0.000278
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	4	4	B.1.36	0.000584
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	4	4	B.1.36.16	0.005698
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	4	4	D.2	0.0003
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	3	3	AY.26	0.000085
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	3	3	AY.9.1	0.000251
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	3	3	B	0.000383
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	3	3	B.1.561	0.001191
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2		0.111111
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	AY.119	0.000071
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	AY.120	0.000074
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	AY.27	0.000129
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	AY.3.1	0.000171
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	AY.36	0.000296
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	AY.46.4	0.000329
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	AY.48	0.00093
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	AY.61	0.00021
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	AY.75	0.000112
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	B.1.1.209	0.017857
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	B.1.1.216	0.001781
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	B.1.1.28	0.000622
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	B.1.1.317	0.000823
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	B.1.1.323	0.028169
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	B.1.1.369	0.000892
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	B.1.1.46	0.008734
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	B.1.160.16	0.001859
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	B.1.177.52	0.003515
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	B.1.177.70	0.011834
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	B.1.206	0.001631
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	B.1.375	0.001639
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	B.1.525	0.000226
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	B.1.618	0.008065
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	B.1.637	0.000146
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	2	2	C.37	0.000232
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	AY.114	0.000231
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	AY.12	0.000316
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	AY.2	0.000356
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	AY.23	0.00007
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	AY.28	0.00189
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	AY.33	0.000067
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	AY.38	0.000499
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	AY.4.4	0.000409
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	AY.54	0.000095
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	AY.66	0.00107
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	AY.70	0.000209
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	AY.71	0.000475
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	AY.74	0.000116
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	AY.94	0.000443
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	AY.98	0.000079
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	AY.98.1	0.000048
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	AY.99	0.001049
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	AY.99.2	0.000092
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.1.1	0.000327
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.1.10	0.001115
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.1.157	0.000913
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.1.168	0.026316
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.1.228	0.003049
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.1.25	0.000569
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.1.263	0.001558
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.1.266	0.012195
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.1.298	0.000862
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.1.365	0.005587
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.1.372	0.000689
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.1.378	0.007299
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.1.39	0.00051
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.1.409	0.002833
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.1.416	0.000905
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.1.464	0.001473
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.1.48	0.002874
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.1.52	0.012195
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.13	0.002375
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.160.14	0.002119
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.177.12	0.000152
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.177.16	0.000664
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.177.2	0.004545
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.177.60	0.000218
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.177.73	0.000566
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.177.87	0.000728
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.210	0.002132
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.221.3	0.000833
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.240	0.000216
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.340	0.004292
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.351.2	0.000303
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.351.3	0.000876
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.36.17	0.000494
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.36.7	0.004
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.361	0.001289
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.416	0.001269
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.427	0.00005
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.432	0.011236
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.499	0.00105
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.517	0.000427
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.565	0.00081
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.575	0.000303
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.596	0.000087
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.619	0.000871
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.8	0.001972
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.1.91	0.002075
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.4	0.002208
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	B.41	0.008
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	C.30	0.001727
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	C.36.3	0.000567
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	P.1.1	0.000318
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	P.1.12	0.000484
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	P.1.15	0.000232
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	P.1.16	0.000374
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	Q.1	0.000126
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	Q.3	0.000145
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	W.3	0.005263
ORF1ab/nsp14A2-B	369	S369F	tCt	tTt	1	1	Z.1	0.00289

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.