CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp14A2-B : Mut = M501L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp14A2-B501M501LM6426LnonsynAtgCtg109910.83486219540-19542
ORF1ab/nsp14A2-B501M501LM6426LnonsynAtgTtg109170.15596319540-19542
ORF1ab/nsp14A2-B501M501LM6426LnonsynAtGCtT10910.0091743119540-19542

Details of the mutation M501L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp14A2-B501M501LAtgCtg91109All0.000017
ORF1ab/nsp14A2-B501M501LAtgTtg17109All0.000003
ORF1ab/nsp14A2-B501M501LAtGCtT1109All0
ORF1ab/nsp14A2-B501M501LAtgCtg3537AY.40.000054
ORF1ab/nsp14A2-B501M501LAtgTtg237AY.40.000003
ORF1ab/nsp14A2-B501M501LAtgCtg3132B.1.1.70.000028
ORF1ab/nsp14A2-B501M501LAtgTtg132B.1.1.70.000001
ORF1ab/nsp14A2-B501M501LAtgCtg66AY.200.000233
ORF1ab/nsp14A2-B501M501LAtgCtg55B.1.617.20.000019
ORF1ab/nsp14A2-B501M501LAtgCtg24AY.430.000009
ORF1ab/nsp14A2-B501M501LAtgTtg24AY.430.000009
ORF1ab/nsp14A2-B501M501LAtgTtg22AY.1020.000053
ORF1ab/nsp14A2-B501M501LAtgTtg22AY.1030.000012
ORF1ab/nsp14A2-B501M501LAtgCtg22AY.1200.000074
ORF1ab/nsp14A2-B501M501LAtgCtg22AY.30.00002
ORF1ab/nsp14A2-B501M501LAtgTtg110.055556
ORF1ab/nsp14A2-B501M501LAtgTtg11AY.230.00007
ORF1ab/nsp14A2-B501M501LAtgCtg11AY.330.000067
ORF1ab/nsp14A2-B501M501LAtgTtg11AY.34.10.00051
ORF1ab/nsp14A2-B501M501LAtgCtg11AY.60.000041
ORF1ab/nsp14A2-B501M501LAtgTtg11AY.750.000056
ORF1ab/nsp14A2-B501M501LAtgCtg11B.10.000009
ORF1ab/nsp14A2-B501M501LAtgCtg11B.1.10.000018
ORF1ab/nsp14A2-B501M501LAtGCtT11B.1.1770.000013
ORF1ab/nsp14A2-B501M501LAtgCtg11B.1.20.000009
ORF1ab/nsp14A2-B501M501LAtgCtg11B.1.2320.000537
ORF1ab/nsp14A2-B501M501LAtgTtg11B.1.3360.002439
ORF1ab/nsp14A2-B501M501LAtgCtg11B.1.3510.00003
ORF1ab/nsp14A2-B501M501LAtgTtg11B.1.4290.000024
ORF1ab/nsp14A2-B501M501LAtgTtg11B.1.4970.000315
ORF1ab/nsp14A2-B501M501LAtgCtg11P.10.000016
ORF1ab/nsp14A2-B501M501LAtgTtg11P.20.000187