CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp14A2-B : Mut = G143G

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF1ab/nsp14A2-B	143	G143G	G6068G	syn	ggA	ggG	10613	10088	0.950532	18466-18468
ORF1ab/nsp14A2-B	143	G143G	G6068G	syn	ggA	ggC	10613	486	0.0457929	18466-18468
ORF1ab/nsp14A2-B	143	G143G	G6068G	syn	ggA	ggT	10613	39	0.00367474	18466-18468

Details of the mutation G143G within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	10088	10613	All	0.001929
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	486	10613	All	0.000093
ORF1ab/nsp14A2-B	143	G143G	ggA	ggT	39	10613	All	0.000007
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	5329	5329	AY.13	0.857856
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	2422	2426	AY.16	0.919514
ORF1ab/nsp14A2-B	143	G143G	ggA	ggT	3	2426	AY.16	0.001139
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	1	2426	AY.16	0.00038
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	796	801	B.1.617.2	0.002997
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	3	801	B.1.617.2	0.000011
ORF1ab/nsp14A2-B	143	G143G	ggA	ggT	2	801	B.1.617.2	0.000008
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	421	421	AY.16.1	0.197838
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	188	188	B.1.232	0.101021
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	161	161	AY.48	0.074884
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	109	118	B.1.1.7	0.000098
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	6	118	B.1.1.7	0.000005
ORF1ab/nsp14A2-B	143	G143G	ggA	ggT	3	118	B.1.1.7	0.000003
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	98	98	AY.18	0.989899
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	80	94	AY.4	0.000125
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	11	94	AY.4	0.000017
ORF1ab/nsp14A2-B	143	G143G	ggA	ggT	3	94	AY.4	0.000005
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	72	84	B.1	0.000659
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	12	84	B.1	0.00011
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	80	80	B.1.567	0.266667
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	64	64	AY.113	0.009113
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	44	44	AY.51	0.04
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	24	43	AY.25	0.000144
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	19	43	AY.25	0.000114
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	37	37	AS.2	0.578125
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	34	35	AY.43	0.000151
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	1	35	AY.43	0.000004
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	30	30	AY.62	0.013072
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	30	30	AY.75	0.001681
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	30	30	B.1.349	0.021444
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	28	28	AY.46	0.002914
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	28	28	AY.55	0.025688
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	24	24	AY.44	0.000146
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	24	24	AY.65	0.012793
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	10	22	P.1	0.000158
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	9	22	P.1	0.000142
ORF1ab/nsp14A2-B	143	G143G	ggA	ggT	3	22	P.1	0.000047
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	18	18	AY.40	0.017358
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	17	18	AY.70	0.003545
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	1	18	AY.70	0.000209
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	16	18	B.1.177	0.000211
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	2	18	B.1.177	0.000026
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	11	14	B.1.1	0.0002
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	3	14	B.1.1	0.000054
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	13	13	AY.75.1	0.002344
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	12	12	AY.54	0.001144
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	12	12	AY.73	0.007984
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	6	12	B.1.526	0.000141
ORF1ab/nsp14A2-B	143	G143G	ggA	ggT	4	12	B.1.526	0.000094
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	2	12	B.1.526	0.000047
ORF1ab/nsp14A2-B	143	G143G	ggA	ggT	11	11	AY.4.2	0.000239
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	5	10	AY.103	0.000031
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	4	10	AY.103	0.000025
ORF1ab/nsp14A2-B	143	G143G	ggA	ggT	1	10	AY.103	0.000006
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	10	10	B.1.617.1	0.00129
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	9	9	AY.46.2	0.005718
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	9	9	AY.52	0.007329
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	8	8	AY.5.4	0.002214
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	6	7	AY.3	0.00006
ORF1ab/nsp14A2-B	143	G143G	ggA	ggT	1	7	AY.3	0.00001
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	7	7	AY.49	0.022364
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	7	7	AY.61	0.000733
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	3	7	B.1.2	0.000026
ORF1ab/nsp14A2-B	143	G143G	ggA	ggT	3	7	B.1.2	0.000026
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	1	7	B.1.2	0.000009
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	6	6	AY.37	0.001896
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	5	6	AY.84	0.002187
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	1	6	AY.84	0.000437
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	6	6	AY.9.2	0.00022
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	6	6	B.1.258	0.000399
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	5	5	AY.118	0.000313
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	5	5	AY.119	0.000177
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	5	5	AY.38	0.002496
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	5	5	AY.39	0.000124
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	5	5	AY.7.2	0.002796
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	5	5	B.1.595	0.001305
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	3	4	AY.7.1	0.000338
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	4	AY.7.1	0.000113
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	3	3	A.2.5	0.001497
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	3	3	AY.10	0.00159
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	3	3	AY.114	0.000693
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	3	3	AY.20	0.000117
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	3	3	AY.26	0.000085
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	3	3	AY.34	0.000291
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	3	3	AY.47	0.000093
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	3	3	AY.68	0.000821
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	3	3	AY.98.1	0.000145
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	3	3	B.1.1.284	0.000322
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	3	3	B.1.214	0.010989
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	2	3	B.1.369	0.00057
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	3	B.1.369	0.000285
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	2	2	AY.1	0.000791
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	2	2	AY.105	0.001286
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	2	2	AY.106	0.00067
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	2	2	AY.111	0.000366
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	2	2	AY.117	0.000169
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	2	2	AY.23	0.000139
ORF1ab/nsp14A2-B	143	G143G	ggA	ggT	1	2	AY.29	0.000016
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	1	2	AY.29	0.000016
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	2	2	AY.36	0.000296
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	2	2	AY.39.1	0.000079
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	2	2	AY.42	0.00008
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	2	2	AY.59	0.001059
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	2	2	AY.78	0.003082
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	2	2	AY.9	0.000135
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	2	AY.9.1	0.000084
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	1	2	AY.9.1	0.000084
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	2	2	AY.98	0.000158
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	2	2	B	0.000256
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	2	2	B.1.1.316	0.00185
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	2	B.1.243	0.00007
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	1	2	B.1.243	0.00007
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	2	2	B.1.351	0.000059
ORF1ab/nsp14A2-B	143	G143G	ggA	ggT	2	2	B.1.422	0.001625
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	2	2	B.1.429	0.000047
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	2	2	B.1.621	0.000177
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	A	0.000387
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	AS.1	0.009524
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	1	1	AY.101	0.00049
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	AY.107	0.000466
ORF1ab/nsp14A2-B	143	G143G	ggA	ggT	1	1	AY.109	0.00074
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	AY.110	0.000113
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	AY.116	0.000287
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	AY.120	0.000037
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	AY.120.1	0.000321
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	1	1	AY.33	0.000067
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	AY.45	0.000122
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	AY.46.4	0.000165
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	1	1	AY.46.5	0.000198
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	AY.58	0.000907
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	AY.67	0.000464
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	AY.72	0.001361
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	AY.90	0.000684
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	AY.92	0.000287
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	AY.93	0.000273
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	AY.99.2	0.000092
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	B.1.1.189	0.001513
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	1	1	B.1.1.228	0.003049
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	B.1.1.306	0.000438
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	B.1.1.318	0.000302
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	1	1	B.1.177.4	0.000211
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	B.1.221	0.000071
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	1	1	B.1.234	0.000132
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	B.1.335	0.010309
ORF1ab/nsp14A2-B	143	G143G	ggA	ggT	1	1	B.1.398	0.002976
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	1	1	B.1.459	0.004082
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	B.1.468	0.005714
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	B.1.596	0.000087
ORF1ab/nsp14A2-B	143	G143G	ggA	ggC	1	1	B.1.623	0.000536
ORF1ab/nsp14A2-B	143	G143G	ggA	ggG	1	1	C.36.3.1	0.002717

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.