CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp14A2-B : Mut = D324Y

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp14A2-B324D324YD6249YnonsynGacTac793279280.99949619009-19011
ORF1ab/nsp14A2-B324D324YD6249YnonsynGaCTaT793240.00050428619009-19011

Details of the mutation D324Y within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp14A2-B324D324YGacTac79287932All0.001516
ORF1ab/nsp14A2-B324D324YGaCTaT47932All0.000001
ORF1ab/nsp14A2-B324D324YGacTac47594761AY.90.321684
ORF1ab/nsp14A2-B324D324YGaCTaT24761AY.90.000135
ORF1ab/nsp14A2-B324D324YGacTac360360B.1.617.20.001356
ORF1ab/nsp14A2-B324D324YGacTac338338B.1.1.70.000303
ORF1ab/nsp14A2-B324D324YGacTac210210B.1.5270.777778
ORF1ab/nsp14A2-B324D324YGacTac181181AY.40.000282
ORF1ab/nsp14A2-B324D324YGacTac172172AY.650.091684
ORF1ab/nsp14A2-B324D324YGacTac9797B.10.000888
ORF1ab/nsp14A2-B324D324YGacTac8989AY.7.10.01003
ORF1ab/nsp14A2-B324D324YGacTac7979B.1.3110.021691
ORF1ab/nsp14A2-B324D324YGacTac7676B.1.5230.186275
ORF1ab/nsp14A2-B324D324YGacTac7070B.1.360.010213
ORF1ab/nsp14A2-B324D324YGacTac6363B.1.1.2220.012852
ORF1ab/nsp14A2-B324D324YGacTac5050AY.250.000301
ORF1ab/nsp14A2-B324D324YGacTac5050AY.430.000222
ORF1ab/nsp14A2-B324D324YGacTac4444AY.75.10.007934
ORF1ab/nsp14A2-B324D324YGacTac4444D.20.003302
ORF1ab/nsp14A2-B324D324YGacTac4343AY.610.004505
ORF1ab/nsp14A2-B324D324YGacTac4343B.1.10.00078
ORF1ab/nsp14A2-B324D324YGacTac4141AY.330.002738
ORF1ab/nsp14A2-B324D324YGacTac4040B.1.6230.021459
ORF1ab/nsp14A2-B324D324YGacTac3939B.1.20.000343
ORF1ab/nsp14A2-B324D324YGacTac3636AY.260.001019
ORF1ab/nsp14A2-B324D324YGacTac3636AY.4.20.000781
ORF1ab/nsp14A2-B324D324YGacTac3636B.1.1600.001123
ORF1ab/nsp14A2-B324D324YGacTac3232P.10.000504
ORF1ab/nsp14A2-B324D324YGacTac3030AY.1020.000795
ORF1ab/nsp14A2-B324D324YGacTac3030B.1.1.10.009801
ORF1ab/nsp14A2-B324D324YGacTac2929B.1.1.2910.021529
ORF1ab/nsp14A2-B324D324YGacTac2727B.1.4530.087379
ORF1ab/nsp14A2-B324D324YGacTac2525AY.1030.000155
ORF1ab/nsp14A2-B324D324YGacTac2424B.1.5260.000564
ORF1ab/nsp14A2-B324D324YGacTac2323B.1.5950.006002
ORF1ab/nsp14A2-B324D324YGacTac2222AK.21
ORF1ab/nsp14A2-B324D324YGacTac2222B.1.6210.001947
ORF1ab/nsp14A2-B324D324YGacTac2020B.1.177.810.003786
ORF1ab/nsp14A2-B324D324YGacTac1919AY.130.003059
ORF1ab/nsp14A2-B324D324YGacTac1919AY.470.000591
ORF1ab/nsp14A2-B324D324YGacTac1818B.1.1.5190.000715
ORF1ab/nsp14A2-B324D324YGacTac1818B.1.3400.077253
ORF1ab/nsp14A2-B324D324YGacTac1616AY.30.000159
ORF1ab/nsp14A2-B324D324YGacTac1616AY.9.20.000588
ORF1ab/nsp14A2-B324D324YGacTac1515AY.540.00143
ORF1ab/nsp14A2-B324D324YGacTac1515P.1.130.013477
ORF1ab/nsp14A2-B324D324YGacTac1414B.1.6190.012195
ORF1ab/nsp14A2-B324D324YGacTac1313AY.4.2.10.001937
ORF1ab/nsp14A2-B324D324YGacTac1212P.1.140.000574
ORF1ab/nsp14A2-B324D324YGacTac1111AY.750.000616
ORF1ab/nsp14A2-B324D324YGacTac1111B.1.1770.000145
ORF1ab/nsp14A2-B324D324YGacTac1010AY.50.000206
ORF1ab/nsp14A2-B324D324YGacTac1010B.1.1.1530.010953
ORF1ab/nsp14A2-B324D324YGacTac1010B.1.1.540.030211
ORF1ab/nsp14A2-B324D324YGacTac99AY.280.017013
ORF1ab/nsp14A2-B324D324YGacTac99B.1.1.4320.011392
ORF1ab/nsp14A2-B324D324YGacTac99C.360.008197
ORF1ab/nsp14A2-B324D324YGacTac88AY.290.000126
ORF1ab/nsp14A2-B324D324YGacTac88AY.3.10.000682
ORF1ab/nsp14A2-B324D324YGacTac88AY.320.00426
ORF1ab/nsp14A2-B324D324YGacTac88B.1.36.290.004139
ORF1ab/nsp14A2-B324D324YGacTac88B.1.617.10.001032
ORF1ab/nsp14A2-B324D324YGacTac77AY.100.00371
ORF1ab/nsp14A2-B324D324YGacTac77AY.350.001631
ORF1ab/nsp14A2-B324D324YGacTac77AY.440.000043
ORF1ab/nsp14A2-B324D324YGacTac77AY.99.20.000645
ORF1ab/nsp14A2-B324D324YGacTac77B.1.1.4460.538462
ORF1ab/nsp14A2-B324D324YGacTac77B.1.2340.000924
ORF1ab/nsp14A2-B324D324YGacTac77B.1.4290.000165
ORF1ab/nsp14A2-B324D324YGacTac66AY.390.000148
ORF1ab/nsp14A2-B324D324YGacTac66AY.670.002786
ORF1ab/nsp14A2-B324D324YGacTac66B.1.1.280.001867
ORF1ab/nsp14A2-B324D324YGacTac66B.1.177.730.003398
ORF1ab/nsp14A2-B324D324YGacTac66P.1.70.001916
ORF1ab/nsp14A2-B324D324YGacTac55AY.1170.000423
ORF1ab/nsp14A2-B324D324YGacTac55AY.230.000349
ORF1ab/nsp14A2-B324D324YGacTac55AY.420.000201
ORF1ab/nsp14A2-B324D324YGacTac55AY.7.20.002796
ORF1ab/nsp14A2-B324D324YGacTac55AY.98.10.000242
ORF1ab/nsp14A2-B324D324YGacTac55B.1.1.2940.006329
ORF1ab/nsp14A2-B324D324YGacTac55B.1.3510.000149
ORF1ab/nsp14A2-B324D324YGacTac55B.1.3910.005637
ORF1ab/nsp14A2-B324D324YGacTac55P.1.100.001347
ORF1ab/nsp14A2-B324D324YGacTac55Q.10.000632
ORF1ab/nsp14A2-B324D324YGacTac240.111111
ORF1ab/nsp14A2-B324D324YGaCTaT240.111111
ORF1ab/nsp14A2-B324D324YGacTac44AY.1200.000149
ORF1ab/nsp14A2-B324D324YGacTac44AY.4.50.00043
ORF1ab/nsp14A2-B324D324YGacTac44AY.510.003636
ORF1ab/nsp14A2-B324D324YGacTac44AY.70.000784
ORF1ab/nsp14A2-B324D324YGacTac44B.1.1.3060.001754
ORF1ab/nsp14A2-B324D324YGacTac44B.1.2320.002149
ORF1ab/nsp14A2-B324D324YGacTac44B.1.36.220.004831
ORF1ab/nsp14A2-B324D324YGacTac44B.1.390.015625
ORF1ab/nsp14A2-B324D324YGacTac44B.1.4000.001716
ORF1ab/nsp14A2-B324D324YGacTac44P.1.150.000929
ORF1ab/nsp14A2-B324D324YGacTac33AY.240.001293
ORF1ab/nsp14A2-B324D324YGacTac33AY.460.000312
ORF1ab/nsp14A2-B324D324YGacTac33AY.46.40.000494
ORF1ab/nsp14A2-B324D324YGacTac33AY.740.000347
ORF1ab/nsp14A2-B324D324YGacTac33AY.9.10.000251
ORF1ab/nsp14A2-B324D324YGacTac33B.1.1.2140.000166
ORF1ab/nsp14A2-B324D324YGacTac33B.1.1.3180.000905
ORF1ab/nsp14A2-B324D324YGacTac33B.1.1.700.001023
ORF1ab/nsp14A2-B324D324YGacTac33B.1.1490.010274
ORF1ab/nsp14A2-B324D324YGacTac33B.1.177.330.004934
ORF1ab/nsp14A2-B324D324YGacTac33B.1.2430.000209
ORF1ab/nsp14A2-B324D324YGacTac33B.1.438.10.000322
ORF1ab/nsp14A2-B324D324YGacTac33B.1.5960.000261
ORF1ab/nsp14A2-B324D324YGacTac33P.20.00056
ORF1ab/nsp14A2-B324D324YGacTac22AY.1060.00067
ORF1ab/nsp14A2-B324D324YGacTac22AY.1070.000932
ORF1ab/nsp14A2-B324D324YGacTac22AY.1160.000574
ORF1ab/nsp14A2-B324D324YGacTac22AY.1180.000125
ORF1ab/nsp14A2-B324D324YGacTac22AY.120.20.002571
ORF1ab/nsp14A2-B324D324YGacTac22AY.1210.000271
ORF1ab/nsp14A2-B324D324YGacTac22AY.160.000759
ORF1ab/nsp14A2-B324D324YGacTac22AY.550.001835
ORF1ab/nsp14A2-B324D324YGacTac22AY.60.000082
ORF1ab/nsp14A2-B324D324YGacTac22AY.680.000547
ORF1ab/nsp14A2-B324D324YGacTac22AY.690.000373
ORF1ab/nsp14A2-B324D324YGacTac22AY.710.00095
ORF1ab/nsp14A2-B324D324YGacTac22AY.850.000854
ORF1ab/nsp14A2-B324D324YGacTac22B0.000256
ORF1ab/nsp14A2-B324D324YGacTac22B.1.1.1890.003026
ORF1ab/nsp14A2-B324D324YGacTac22B.1.1.2410.004141
ORF1ab/nsp14A2-B324D324YGacTac22B.1.1.2840.000215
ORF1ab/nsp14A2-B324D324YGacTac22B.1.1.3030.005525
ORF1ab/nsp14A2-B324D324YGacTac22B.1.1.3260.003521
ORF1ab/nsp14A2-B324D324YGacTac22B.1.1.390.001019
ORF1ab/nsp14A2-B324D324YGacTac22B.1.1.3980.006452
ORF1ab/nsp14A2-B324D324YGacTac22B.1.177.170.001642
ORF1ab/nsp14A2-B324D324YGacTac22B.1.1790.007519
ORF1ab/nsp14A2-B324D324YGacTac22B.1.2210.000142
ORF1ab/nsp14A2-B324D324YGacTac22B.1.2370.00995
ORF1ab/nsp14A2-B324D324YGacTac22B.1.2580.000133
ORF1ab/nsp14A2-B324D324YGacTac22B.1.258.110.000793
ORF1ab/nsp14A2-B324D324YGacTac22B.1.3160.222222
ORF1ab/nsp14A2-B324D324YGacTac22B.1.3190.006098
ORF1ab/nsp14A2-B324D324YGacTac22B.1.3660.009756
ORF1ab/nsp14A2-B324D324YGacTac22B.1.400.039216
ORF1ab/nsp14A2-B324D324YGacTac22B.1.4270.000101
ORF1ab/nsp14A2-B324D324YGacTac22B.1.5650.001621
ORF1ab/nsp14A2-B324D324YGacTac22B.1.619.10.001283
ORF1ab/nsp14A2-B324D324YGacTac22B.1.6370.000146
ORF1ab/nsp14A2-B324D324YGacTac22C.36.30.001134
ORF1ab/nsp14A2-B324D324YGacTac22C.370.000232
ORF1ab/nsp14A2-B324D324YGacTac11A.20.000662
ORF1ab/nsp14A2-B324D324YGacTac11A.2.50.000499
ORF1ab/nsp14A2-B324D324YGacTac11A.2.5.10.004808
ORF1ab/nsp14A2-B324D324YGacTac11AY.1100.000113
ORF1ab/nsp14A2-B324D324YGacTac11AY.1130.000142
ORF1ab/nsp14A2-B324D324YGacTac11AY.140.000088
ORF1ab/nsp14A2-B324D324YGacTac11AY.200.000039
ORF1ab/nsp14A2-B324D324YGacTac11AY.270.000065
ORF1ab/nsp14A2-B324D324YGacTac11AY.300.000396
ORF1ab/nsp14A2-B324D324YGacTac11AY.340.000097
ORF1ab/nsp14A2-B324D324YGacTac11AY.360.000148
ORF1ab/nsp14A2-B324D324YGacTac11AY.39.10.00004
ORF1ab/nsp14A2-B324D324YGacTac11AY.4.30.000842
ORF1ab/nsp14A2-B324D324YGacTac11AY.4.40.000409
ORF1ab/nsp14A2-B324D324YGacTac11AY.400.000964
ORF1ab/nsp14A2-B324D324YGacTac11AY.530.000288
ORF1ab/nsp14A2-B324D324YGacTac11AY.600.000938
ORF1ab/nsp14A2-B324D324YGacTac11AY.630.000387
ORF1ab/nsp14A2-B324D324YGacTac11AY.730.000665
ORF1ab/nsp14A2-B324D324YGacTac11AY.9.2.10.001976
ORF1ab/nsp14A2-B324D324YGacTac11AY.940.000443
ORF1ab/nsp14A2-B324D324YGacTac11AY.950.000761
ORF1ab/nsp14A2-B324D324YGacTac11AY.980.000079
ORF1ab/nsp14A2-B324D324YGacTac11AY.990.001049
ORF1ab/nsp14A2-B324D324YGacTac11B.1.1.1210.002427
ORF1ab/nsp14A2-B324D324YGacTac11B.1.1.1350.004695
ORF1ab/nsp14A2-B324D324YGacTac11B.1.1.2050.003717
ORF1ab/nsp14A2-B324D324YGacTac11B.1.1.2320.001815
ORF1ab/nsp14A2-B324D324YGacTac11B.1.1.250.000569
ORF1ab/nsp14A2-B324D324YGacTac11B.1.1.2770.000759
ORF1ab/nsp14A2-B324D324YGacTac11B.1.1.3110.000358
ORF1ab/nsp14A2-B324D324YGacTac11B.1.1.4100.037037
ORF1ab/nsp14A2-B324D324YGacTac11B.1.1.440.00241
ORF1ab/nsp14A2-B324D324YGacTac11B.1.1.470.005348
ORF1ab/nsp14A2-B324D324YGacTac11B.1.1.4870.005587
ORF1ab/nsp14A2-B324D324YGacTac11B.1.1.5230.001563
ORF1ab/nsp14A2-B324D324YGacTac11B.1.1.5250.005464
ORF1ab/nsp14A2-B324D324YGacTac11B.1.1030.019231
ORF1ab/nsp14A2-B324D324YGacTac11B.1.1110.001175
ORF1ab/nsp14A2-B324D324YGacTac11B.1.1470.000756
ORF1ab/nsp14A2-B324D324YGacTac11B.1.177.350.000691
ORF1ab/nsp14A2-B324D324YGacTac11B.1.177.600.000218
ORF1ab/nsp14A2-B324D324YGacTac11B.1.2030.0625
ORF1ab/nsp14A2-B324D324YGacTac11B.1.2100.002132
ORF1ab/nsp14A2-B324D324YGacTac11B.1.220.001318
ORF1ab/nsp14A2-B324D324YGacTac11B.1.2350.002519
ORF1ab/nsp14A2-B324D324YGacTac11B.1.2400.000216
ORF1ab/nsp14A2-B324D324YGacTac11B.1.3460.001311
ORF1ab/nsp14A2-B324D324YGacTac11B.1.351.20.000303
ORF1ab/nsp14A2-B324D324YGacTac11B.1.36.10.00114
ORF1ab/nsp14A2-B324D324YGacTac11B.1.36.160.001425
ORF1ab/nsp14A2-B324D324YGacTac11B.1.3690.000285
ORF1ab/nsp14A2-B324D324YGacTac11B.1.4330.003195
ORF1ab/nsp14A2-B324D324YGacTac11B.1.4560.003268
ORF1ab/nsp14A2-B324D324YGacTac11B.1.5040.03125
ORF1ab/nsp14A2-B324D324YGacTac11B.1.517.10.005263
ORF1ab/nsp14A2-B324D324YGacTac11B.1.5250.000113
ORF1ab/nsp14A2-B324D324YGacTac11B.1.5640.000426
ORF1ab/nsp14A2-B324D324YGacTac11B.1.6000.005848
ORF1ab/nsp14A2-B324D324YGacTac11B.1.617.30.002985
ORF1ab/nsp14A2-B324D324YGacTac11B.1.621.10.000506
ORF1ab/nsp14A2-B324D324YGacTac11B.4.50.011905
ORF1ab/nsp14A2-B324D324YGacTac11B.60.00091
ORF1ab/nsp14A2-B324D324YGacTac11C.10.002392
ORF1ab/nsp14A2-B324D324YGacTac11P.1.170.000162
ORF1ab/nsp14A2-B324D324YGacTac11Q.80.000165
ORF1ab/nsp14A2-B324D324YGacTac11W.40.001351

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.