CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp14A2-B : Mut = A119S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp14A2-B119A119SA6044SnonsynGctTct163016270.9981618394-18396
ORF1ab/nsp14A2-B119A119SA6044SnonsynGCtAGt163010.00061349718394-18396
ORF1ab/nsp14A2-B119A119SA6044SnonsynGcTTcC163010.00061349718394-18396
ORF1ab/nsp14A2-B119A119SA6044SnonsynGcTTcG163010.00061349718394-18396

Details of the mutation A119S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp14A2-B119A119SGctTct16271630All0.000311
ORF1ab/nsp14A2-B119A119SGcTTcG11630All0
ORF1ab/nsp14A2-B119A119SGCtAGt11630All0
ORF1ab/nsp14A2-B119A119SGcTTcC11630All0
ORF1ab/nsp14A2-B119A119SGctTct347347AY.30.003451
ORF1ab/nsp14A2-B119A119SGctTct254254AY.40.000395
ORF1ab/nsp14A2-B119A119SGctTct162162B.1.1.70.000145
ORF1ab/nsp14A2-B119A119SGctTct9090AY.50.001858
ORF1ab/nsp14A2-B119A119SGctTct8080B.1.617.20.000301
ORF1ab/nsp14A2-B119A119SGctTct5858AY.440.000353
ORF1ab/nsp14A2-B119A119SGctTct4949B.1.1.5190.001946
ORF1ab/nsp14A2-B119A119SGctTct4141B.1.3510.001219
ORF1ab/nsp14A2-B119A119SGctTct3030AA.10.217391
ORF1ab/nsp14A2-B119A119SGctTct3030AY.420.001207
ORF1ab/nsp14A2-B119A119SGctTct2525B.1.2580.001664
ORF1ab/nsp14A2-B119A119SGctTct2424AY.430.000106
ORF1ab/nsp14A2-B119A119SGctTct2222AY.1030.000137
ORF1ab/nsp14A2-B119A119SGctTct2020B.1.20.000176
ORF1ab/nsp14A2-B119A119SGctTct1718B.10.000156
ORF1ab/nsp14A2-B119A119SGCtAGt118B.10.000009
ORF1ab/nsp14A2-B119A119SGctTct1717AY.330.001135
ORF1ab/nsp14A2-B119A119SGctTct1313AY.250.000078
ORF1ab/nsp14A2-B119A119SGctTct1212AY.4.20.00026
ORF1ab/nsp14A2-B119A119SGctTct1212P.10.000189
ORF1ab/nsp14A2-B119A119SGctTct1010AY.260.000283
ORF1ab/nsp14A2-B119A119SGctTct1010AY.390.000247
ORF1ab/nsp14A2-B119A119SGctTct1010AY.680.002737
ORF1ab/nsp14A2-B119A119SGctTct1010B.1.1.4841
ORF1ab/nsp14A2-B119A119SGctTct1010B.1.360.001459
ORF1ab/nsp14A2-B119A119SGctTct1010B.1.4090.007812
ORF1ab/nsp14A2-B119A119SGctTct99AY.200.00035
ORF1ab/nsp14A2-B119A119SGctTct99B.1.1770.000119
ORF1ab/nsp14A2-B119A119SGctTct88AY.450.000973
ORF1ab/nsp14A2-B119A119SGctTct77AY.1020.000186
ORF1ab/nsp14A2-B119A119SGctTct77AY.1110.001282
ORF1ab/nsp14A2-B119A119SGctTct77AY.290.00011
ORF1ab/nsp14A2-B119A119SGctTct77AY.39.10.000277
ORF1ab/nsp14A2-B119A119SGctTct77B.1.3690.001997
ORF1ab/nsp14A2-B119A119SGctTct77C.370.000812
ORF1ab/nsp14A2-B119A119SGctTct66AY.120.001896
ORF1ab/nsp14A2-B119A119SGctTct66B.1.10.000109
ORF1ab/nsp14A2-B119A119SGctTct66B.1.1.10.00196
ORF1ab/nsp14A2-B119A119SGctTct66B.1.1600.000187
ORF1ab/nsp14A2-B119A119SGctTct66B.1.4270.000303
ORF1ab/nsp14A2-B119A119SGctTct66B.1.4290.000141
ORF1ab/nsp14A2-B119A119SGctTct55AY.1000.00023
ORF1ab/nsp14A2-B119A119SGctTct55AY.610.000524
ORF1ab/nsp14A2-B119A119SGctTct55AY.920.001436
ORF1ab/nsp14A2-B119A119SGctTct44AY.700.000834
ORF1ab/nsp14A2-B119A119SGctTct44B.1.1.2910.00297
ORF1ab/nsp14A2-B119A119SGctTct44B.1.4780.047059
ORF1ab/nsp14A2-B119A119SGcTTcC130.055556
ORF1ab/nsp14A2-B119A119SGcTTcG130.055556
ORF1ab/nsp14A2-B119A119SGctTct130.055556
ORF1ab/nsp14A2-B119A119SGctTct33AY.360.000445
ORF1ab/nsp14A2-B119A119SGctTct33AY.470.000093
ORF1ab/nsp14A2-B119A119SGctTct33AY.590.001589
ORF1ab/nsp14A2-B119A119SGctTct33AY.9.10.000251
ORF1ab/nsp14A2-B119A119SGctTct33AY.9.20.00011
ORF1ab/nsp14A2-B119A119SGctTct33AY.910.002191
ORF1ab/nsp14A2-B119A119SGctTct33B.1.1.3170.001235
ORF1ab/nsp14A2-B119A119SGctTct33B.1.1.3690.001339
ORF1ab/nsp14A2-B119A119SGctTct33B.1.2210.000213
ORF1ab/nsp14A2-B119A119SGctTct33W.40.004054
ORF1ab/nsp14A2-B119A119SGctTct22AY.1170.000169
ORF1ab/nsp14A2-B119A119SGctTct22AY.270.000129
ORF1ab/nsp14A2-B119A119SGctTct22AY.3.10.000171
ORF1ab/nsp14A2-B119A119SGctTct22AY.4.50.000215
ORF1ab/nsp14A2-B119A119SGctTct22AY.730.001331
ORF1ab/nsp14A2-B119A119SGctTct22AY.750.000112
ORF1ab/nsp14A2-B119A119SGctTct22AY.90.000135
ORF1ab/nsp14A2-B119A119SGctTct22AY.940.000885
ORF1ab/nsp14A2-B119A119SGctTct22B.1.1.2220.000408
ORF1ab/nsp14A2-B119A119SGctTct22B.1.1.280.000622
ORF1ab/nsp14A2-B119A119SGctTct22B.1.177.770.001452
ORF1ab/nsp14A2-B119A119SGctTct22B.1.177.810.000379
ORF1ab/nsp14A2-B119A119SGctTct22B.1.2430.000139
ORF1ab/nsp14A2-B119A119SGctTct22B.1.3110.000549
ORF1ab/nsp14A2-B119A119SGctTct22B.1.36.290.001035
ORF1ab/nsp14A2-B119A119SGctTct22B.1.36.80.002
ORF1ab/nsp14A2-B119A119SGctTct22B.1.466.20.000782
ORF1ab/nsp14A2-B119A119SGctTct22Q.10.000253
ORF1ab/nsp14A2-B119A119SGctTct11AD.20.000219
ORF1ab/nsp14A2-B119A119SGctTct11AE.80.000489
ORF1ab/nsp14A2-B119A119SGctTct11AY.1050.000643
ORF1ab/nsp14A2-B119A119SGctTct11AY.1060.000335
ORF1ab/nsp14A2-B119A119SGctTct11AY.1130.000142
ORF1ab/nsp14A2-B119A119SGctTct11AY.1140.000231
ORF1ab/nsp14A2-B119A119SGctTct11AY.1200.000037
ORF1ab/nsp14A2-B119A119SGctTct11AY.120.20.001285
ORF1ab/nsp14A2-B119A119SGctTct11AY.160.00038
ORF1ab/nsp14A2-B119A119SGctTct11AY.16.10.00047
ORF1ab/nsp14A2-B119A119SGctTct11AY.190.00114
ORF1ab/nsp14A2-B119A119SGctTct11AY.230.00007
ORF1ab/nsp14A2-B119A119SGctTct11AY.23.10.000417
ORF1ab/nsp14A2-B119A119SGctTct11AY.320.000532
ORF1ab/nsp14A2-B119A119SGctTct11AY.340.000097
ORF1ab/nsp14A2-B119A119SGctTct11AY.380.000499
ORF1ab/nsp14A2-B119A119SGctTct11AY.46.60.000072
ORF1ab/nsp14A2-B119A119SGctTct11AY.5.20.002463
ORF1ab/nsp14A2-B119A119SGctTct11AY.5.40.000277
ORF1ab/nsp14A2-B119A119SGctTct11AY.540.000095
ORF1ab/nsp14A2-B119A119SGctTct11AY.690.000187
ORF1ab/nsp14A2-B119A119SGctTct11AY.75.10.00018
ORF1ab/nsp14A2-B119A119SGctTct11AY.790.001211
ORF1ab/nsp14A2-B119A119SGctTct11AY.960.002075
ORF1ab/nsp14A2-B119A119SGctTct11AZ.10.000867
ORF1ab/nsp14A2-B119A119SGctTct11B0.000128
ORF1ab/nsp14A2-B119A119SGctTct11B.1.1.1740.003378
ORF1ab/nsp14A2-B119A119SGctTct11B.1.1.2140.000055
ORF1ab/nsp14A2-B119A119SGctTct11B.1.1.2200.001859
ORF1ab/nsp14A2-B119A119SGctTct11B.1.1.2210.010101
ORF1ab/nsp14A2-B119A119SGctTct11B.1.1.2560.013699
ORF1ab/nsp14A2-B119A119SGctTct11B.1.1.3220.008772
ORF1ab/nsp14A2-B119A119SGctTct11B.1.1.4480.002033
ORF1ab/nsp14A2-B119A119SGctTct11B.1.1.630.000386
ORF1ab/nsp14A2-B119A119SGctTct11B.1.110.30.000718
ORF1ab/nsp14A2-B119A119SGctTct11B.1.1390.000733
ORF1ab/nsp14A2-B119A119SGctTct11B.1.177.170.000821
ORF1ab/nsp14A2-B119A119SGctTct11B.1.177.520.001757
ORF1ab/nsp14A2-B119A119SGctTct11B.1.177.70.000165
ORF1ab/nsp14A2-B119A119SGctTct11B.1.214.20.0006
ORF1ab/nsp14A2-B119A119SGctTct11B.1.258.170.000104
ORF1ab/nsp14A2-B119A119SGctTct11B.1.2790.000514
ORF1ab/nsp14A2-B119A119SGctTct11B.1.3200.001245
ORF1ab/nsp14A2-B119A119SGctTct11B.1.36.170.000494
ORF1ab/nsp14A2-B119A119SGctTct11B.1.36.380.001642
ORF1ab/nsp14A2-B119A119SGctTct11B.1.3960.000706
ORF1ab/nsp14A2-B119A119SGctTct11B.1.438.10.000107
ORF1ab/nsp14A2-B119A119SGctTct11B.1.4700.001404
ORF1ab/nsp14A2-B119A119SGctTct11B.1.4990.00105
ORF1ab/nsp14A2-B119A119SGctTct11B.1.5170.000427
ORF1ab/nsp14A2-B119A119SGctTct11B.1.5250.000113
ORF1ab/nsp14A2-B119A119SGctTct11B.1.5260.000024
ORF1ab/nsp14A2-B119A119SGctTct11B.1.5440.006024
ORF1ab/nsp14A2-B119A119SGctTct11B.1.6190.000871
ORF1ab/nsp14A2-B119A119SGctTct11B.1.6280.000352
ORF1ab/nsp14A2-B119A119SGctTct11B.1.6370.000073
ORF1ab/nsp14A2-B119A119SGctTct11B.40.002208
ORF1ab/nsp14A2-B119A119SGctTct11C.260.007353
ORF1ab/nsp14A2-B119A119SGctTct11L.30.003546
ORF1ab/nsp14A2-B119A119SGctTct11N.50.001767
ORF1ab/nsp14A2-B119A119SGctTct11N.60.007092
ORF1ab/nsp14A2-B119A119SGctTct11P.1.120.000484
ORF1ab/nsp14A2-B119A119SGctTct11P.20.000187
ORF1ab/nsp14A2-B119A119SGctTct11P.70.004367
ORF1ab/nsp14A2-B119A119SGctTct11Q.70.001111
ORF1ab/nsp14A2-B119A119SGctTct11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.