CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp14A2-B : CodonNum = 74

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF1ab/nsp14A2-B	74	I74I	I5999I	syn	atC	atT	1773	1548	0.873096	18259-18261
ORF1ab/nsp14A2-B	74	I74I	I5999I	syn	atC	atA	1773	225	0.126904	18259-18261
ORF1ab/nsp14A2-B	74	I74V	I5999V	nonsyn	Atc	Gtc	959	954	0.994786	18259-18261
ORF1ab/nsp14A2-B	74	I74V	I5999V	nonsyn	AtC	GtG	959	4	0.00417101	18259-18261
ORF1ab/nsp14A2-B	74	I74V	I5999V	nonsyn	AtC	GtT	959	1	0.00104275	18259-18261
ORF1ab/nsp14A2-B	74	I74T	I5999T	nonsyn	aTc	aCc	792	792	1	18259-18261
ORF1ab/nsp14A2-B	74	I74S	I5999S	nonsyn	aTc	aGc	60	59	0.983333	18259-18261
ORF1ab/nsp14A2-B	74	I74S	I5999S	nonsyn	aTC	aGT	60	1	0.0166667	18259-18261
ORF1ab/nsp14A2-B	74	I74N	I5999N	nonsyn	aTc	aAc	17	17	1	18259-18261
ORF1ab/nsp14A2-B	74	I74del	I5999del	del	ATC	---	13	13	1	18259-18261
ORF1ab/nsp14A2-B	74	I74F	I5999F	nonsyn	Atc	Ttc	9	9	1	18259-18261
ORF1ab/nsp14A2-B	74	I74M	I5999M	nonsyn	atC	atG	6	6	1	18259-18261
ORF1ab/nsp14A2-B	74	I74del2	I5999del2	del	aTC	a--	4	3	0.75	18259-18261
ORF1ab/nsp14A2-B	74	I74G	I5999G	nonsyn	ATC	GGG	4	2	0.5	18259-18261
ORF1ab/nsp14A2-B	74	I74G	I5999G	nonsyn	ATC	GGT	4	2	0.5	18259-18261
ORF1ab/nsp14A2-B	74	I74del2	I5999del2	del	ATc	--c	4	1	0.25	18259-18261
ORF1ab/nsp14A2-B	74	I74L	I5999L	nonsyn	Atc	Ctc	2	2	1	18259-18261
ORF1ab/nsp14A2-B	74	I74W	I5999W	nonsyn	ATC	TGG	1	1	1	18259-18261
ORF1ab/nsp14A2-B	74	I74del1	I5999del1	del	aTc	a-c	1	1	1	18259-18261
ORF1ab/nsp14A2-B	74	I74C	I5999C	nonsyn	ATC	TGT	1	1	1	18259-18261
ORF1ab/nsp14A2-B	74	I74R	I5999R	nonsyn	aTC	aGG	1	1	1	18259-18261

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1548	1773	All	0.000296
ORF1ab/nsp14A2-B	74	I74I	atC	atA	225	1773	All	0.000043
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	954	959	All	0.000182
ORF1ab/nsp14A2-B	74	I74V	AtC	GtG	4	959	All	0.000001
ORF1ab/nsp14A2-B	74	I74V	AtC	GtT	1	959	All	0
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	792	792	All	0.000151
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	432	432	B.1.1.7	0.000387
ORF1ab/nsp14A2-B	74	I74I	atC	atT	273	274	B.1.1.7	0.000244
ORF1ab/nsp14A2-B	74	I74I	atC	atA	1	274	B.1.1.7	0.000001
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	236	236	AY.4	0.000367
ORF1ab/nsp14A2-B	74	I74I	atC	atA	120	220	AY.3	0.001194
ORF1ab/nsp14A2-B	74	I74I	atC	atT	100	220	AY.3	0.000995
ORF1ab/nsp14A2-B	74	I74I	atC	atT	162	168	B.1.617.2	0.00061
ORF1ab/nsp14A2-B	74	I74I	atC	atA	6	168	B.1.617.2	0.000023
ORF1ab/nsp14A2-B	74	I74I	atC	atT	127	134	AY.4	0.000198
ORF1ab/nsp14A2-B	74	I74I	atC	atA	7	134	AY.4	0.000011
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	103	103	B.1.1.7	0.000092
ORF1ab/nsp14A2-B	74	I74I	atC	atT	99	99	AY.102	0.002625
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	83	83	B.1.1.170	0.103491
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	79	79	B.1.177.20	0.119879
ORF1ab/nsp14A2-B	74	I74I	atC	atT	75	75	B.1.429	0.001765
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	71	71	A.21	0.196676
ORF1ab/nsp14A2-B	74	I74S	aTc	aGc	59	60	All	0.000011
ORF1ab/nsp14A2-B	74	I74S	aTC	aGT	1	60	All	0
ORF1ab/nsp14A2-B	74	I74I	atC	atT	55	58	AY.44	0.000335
ORF1ab/nsp14A2-B	74	I74I	atC	atA	3	58	AY.44	0.000018
ORF1ab/nsp14A2-B	74	I74I	atC	atA	46	57	B.1.1	0.000834
ORF1ab/nsp14A2-B	74	I74I	atC	atT	11	57	B.1.1	0.0002
ORF1ab/nsp14A2-B	74	I74I	atC	atT	54	54	AY.111	0.00989
ORF1ab/nsp14A2-B	74	I74I	atC	atT	54	54	B.1.427	0.002727
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	53	53	C.35	0.041022
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	47	47	AY.113	0.006692
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	39	39	AY.44	0.000237
ORF1ab/nsp14A2-B	74	I74I	atC	atT	37	37	B.1.177	0.000487
ORF1ab/nsp14A2-B	74	I74I	atC	atT	35	35	AY.47	0.001089
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	32	32	B.1.1.328	0.542373
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	31	32	B.1.617.2	0.000117
ORF1ab/nsp14A2-B	74	I74V	AtC	GtG	1	32	B.1.617.2	0.000004
ORF1ab/nsp14A2-B	74	I74I	atC	atT	27	29	AY.103	0.000168
ORF1ab/nsp14A2-B	74	I74I	atC	atA	2	29	AY.103	0.000012
ORF1ab/nsp14A2-B	74	I74I	atC	atT	29	29	B.1.1.464	0.04271
ORF1ab/nsp14A2-B	74	I74I	atC	atT	29	29	P.1	0.000457
ORF1ab/nsp14A2-B	74	I74I	atC	atT	27	28	B.1.2	0.000238
ORF1ab/nsp14A2-B	74	I74I	atC	atA	1	28	B.1.2	0.000009
ORF1ab/nsp14A2-B	74	I74I	atC	atT	27	27	B.1.1.25	0.01535
ORF1ab/nsp14A2-B	74	I74I	atC	atT	21	24	B.1	0.000192
ORF1ab/nsp14A2-B	74	I74I	atC	atA	3	24	B.1	0.000027
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	23	23	B.1.399	0.044487
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	22	22	AY.25	0.000132
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	22	22	B.1.2	0.000194
ORF1ab/nsp14A2-B	74	I74I	atC	atT	22	22	P.1.14	0.001052
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	21	21	AY.4	0.000033
ORF1ab/nsp14A2-B	74	I74I	atC	atT	20	20	AY.29	0.000315
ORF1ab/nsp14A2-B	74	I74I	atC	atT	16	19	AY.43	0.000071
ORF1ab/nsp14A2-B	74	I74I	atC	atA	3	19	AY.43	0.000013
ORF1ab/nsp14A2-B	74	I74I	atC	atT	17	18	B.1.595	0.004436
ORF1ab/nsp14A2-B	74	I74I	atC	atA	1	18	B.1.595	0.000261
ORF1ab/nsp14A2-B	74	I74N	aTc	aAc	17	17	All	0.000003
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	16	16	AY.3	0.000159
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	16	16	B.1.1	0.00029
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	16	16	B.1.160.31	0.129032
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	15	15	B.1.619	0.013066
ORF1ab/nsp14A2-B	74	I74del	ATC	---	13	13	All	0.000002
ORF1ab/nsp14A2-B	74	I74S	aTc	aGc	13	13	B.1.177.17	0.010673
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	12	12	AY.39	0.000297
ORF1ab/nsp14A2-B	74	I74I	atC	atT	10	12	AY.39	0.000247
ORF1ab/nsp14A2-B	74	I74I	atC	atA	2	12	AY.39	0.000049
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	12	12	AY.43	0.000053
ORF1ab/nsp14A2-B	74	I74I	atC	atA	10	12	AY.74	0.001156
ORF1ab/nsp14A2-B	74	I74I	atC	atT	2	12	AY.74	0.000231
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	12	12	B.1	0.00011
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	11	12	B.1	0.000101
ORF1ab/nsp14A2-B	74	I74V	AtC	GtG	1	12	B.1	0.000009
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	12	12	B.1.429	0.000282
ORF1ab/nsp14A2-B	74	I74I	atC	atT	10	11	AY.25	0.00006
ORF1ab/nsp14A2-B	74	I74I	atC	atA	1	11	AY.25	0.000006
ORF1ab/nsp14A2-B	74	I74S	aTc	aGc	11	11	B.1.1.7	0.00001
ORF1ab/nsp14A2-B	74	I74S	aTc	aGc	11	11	B.1.2	0.000097
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	10	10	B.1.2	0.000088
ORF1ab/nsp14A2-B	74	I74F	Atc	Ttc	9	9	All	0.000002
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	9	9	AY.114	0.00208
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	9	9	AY.12	0.002845
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	9	9	AY.20	0.00035
ORF1ab/nsp14A2-B	74	I74I	atC	atT	8	9	AY.4.2	0.000174
ORF1ab/nsp14A2-B	74	I74I	atC	atA	1	9	AY.4.2	0.000022
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	9	9	B.1.177	0.000119
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	8	8	AY.107	0.003728
ORF1ab/nsp14A2-B	74	I74I	atC	atT	8	8	AY.26	0.000226
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	8	8	AY.26	0.000226
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	8	8	AY.29	0.000126
ORF1ab/nsp14A2-B	74	I74I	atC	atT	8	8	AY.45	0.000973
ORF1ab/nsp14A2-B	74	I74I	atC	atT	6	8	B.1.1.519	0.000238
ORF1ab/nsp14A2-B	74	I74I	atC	atA	2	8	B.1.1.519	0.000079
ORF1ab/nsp14A2-B	74	I74I	atC	atT	8	8	B.1.234	0.001056
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	8	8	B.1.617.2	0.00003
ORF1ab/nsp14A2-B	74	I74I	atC	atT	8	8	Q.2	0.004908
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	7	7	AY.25	0.000042
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	7	7	B.1.320	0.008717
ORF1ab/nsp14A2-B	74	I74M	atC	atG	6	6	All	0.000001
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	6	6	AY.100	0.000276
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	6	6	AY.103	0.000037
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	6	6	AY.26	0.00017
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	6	6	AY.43	0.000027
ORF1ab/nsp14A2-B	74	I74S	aTc	aGc	6	6	AY.43	0.000027
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	6	6	B.1.1.214	0.000333
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	6	6	B.1.1.519	0.000238
ORF1ab/nsp14A2-B	74	I74I	atC	atT	6	6	B.1.111	0.007051
ORF1ab/nsp14A2-B	74	I74I	atC	atT	6	6	B.1.526	0.000141
ORF1ab/nsp14A2-B	74	I74I	atC	atA	4	6	B.1.596	0.000349
ORF1ab/nsp14A2-B	74	I74I	atC	atT	2	6	B.1.596	0.000174
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	5	5	AY.119	0.000177
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	5	5	AY.29	0.000079
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	5	5	AY.34	0.000485
ORF1ab/nsp14A2-B	74	I74F	Atc	Ttc	5	5	AY.39.1	0.000198
ORF1ab/nsp14A2-B	74	I74I	atC	atT	5	5	AY.39.1.1	0.003623
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	5	5	B.1.243	0.000348
ORF1ab/nsp14A2-B	74	I74I	atC	atT	5	5	B.1.637	0.000365
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	5	5	P.1	0.000079
ORF1ab/nsp14A2-B	74	I74del2	aTC	a--	3	4	All	0.000001
ORF1ab/nsp14A2-B	74	I74G	ATC	GGG	2	4	All	0
ORF1ab/nsp14A2-B	74	I74G	ATC	GGT	2	4	All	0
ORF1ab/nsp14A2-B	74	I74del2	ATc	--c	1	4	All	0
ORF1ab/nsp14A2-B	74	I74I	atC	atT	4	4	AY.14	0.000352
ORF1ab/nsp14A2-B	74	I74I	atC	atT	4	4	AY.23.1	0.001669
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	4	4	AY.3	0.00004
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	4	4	AY.44	0.000024
ORF1ab/nsp14A2-B	74	I74I	atC	atT	4	4	AY.46.4	0.000658
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	4	4	B.1.1.317	0.001647
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	4	4	B.1.1.438	0.2
ORF1ab/nsp14A2-B	74	I74N	aTc	aAc	4	4	B.1.1.7	0.000004
ORF1ab/nsp14A2-B	74	I74I	atC	atT	4	4	B.1.127	0.008791
ORF1ab/nsp14A2-B	74	I74I	atC	atT	4	4	B.1.258.17	0.000416
ORF1ab/nsp14A2-B	74	I74I	atC	atT	4	4	B.1.351	0.000119
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	4	4	B.1.427	0.000202
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	4	4	B.1.628	0.001409
ORF1ab/nsp14A2-B	74	I74I	atC	atT	4	4	D.2	0.0003
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	4	4	P.1	0.000063
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	3	3	AY.102	0.00008
ORF1ab/nsp14A2-B	74	I74I	atC	atT	2	3	AY.117	0.000169
ORF1ab/nsp14A2-B	74	I74I	atC	atA	1	3	AY.117	0.000085
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	3	3	AY.2	0.001068
ORF1ab/nsp14A2-B	74	I74I	atC	atT	3	3	AY.23	0.000209
ORF1ab/nsp14A2-B	74	I74S	aTc	aGc	3	3	AY.33	0.0002
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	3	3	AY.4.2	0.000065
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	3	3	AY.45	0.000365
ORF1ab/nsp14A2-B	74	I74I	atC	atT	3	3	AY.46.2	0.001906
ORF1ab/nsp14A2-B	74	I74I	atC	atA	2	3	AY.54	0.000191
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	3	AY.54	0.000095
ORF1ab/nsp14A2-B	74	I74I	atC	atT	3	3	AY.9.2	0.00011
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	3	3	B.1.1.15	0.040541
ORF1ab/nsp14A2-B	74	I74del	ATC	---	3	3	B.1.1.7	0.000003
ORF1ab/nsp14A2-B	74	I74I	atC	atT	3	3	B.1.177.6	0.00293
ORF1ab/nsp14A2-B	74	I74I	atC	atT	3	3	B.1.177.77	0.002179
ORF1ab/nsp14A2-B	74	I74I	atC	atT	3	3	B.1.36	0.000438
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	3	3	B.1.36	0.000438
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	3	3	B.1.526	0.000071
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	3	3	B.1.582	0.001472
ORF1ab/nsp14A2-B	74	I74I	atC	atT	3	3	B.1.617.1	0.000387
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	2	2	A.2.5.3	0.020619
ORF1ab/nsp14A2-B	74	I74L	Atc	Ctc	2	2	All	0
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	2	AY.100	0.000046
ORF1ab/nsp14A2-B	74	I74I	atC	atA	1	2	AY.100	0.000046
ORF1ab/nsp14A2-B	74	I74I	atC	atT	2	2	AY.110	0.000225
ORF1ab/nsp14A2-B	74	I74S	aTc	aGc	2	2	AY.113	0.000285
ORF1ab/nsp14A2-B	74	I74V	AtC	GtG	1	2	AY.113	0.000142
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	2	AY.113	0.000142
ORF1ab/nsp14A2-B	74	I74I	atC	atT	2	2	AY.116	0.000574
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	2	2	AY.116	0.000574
ORF1ab/nsp14A2-B	74	I74I	atC	atT	2	2	AY.116.1	0.000623
ORF1ab/nsp14A2-B	74	I74I	atC	atT	2	2	AY.119	0.000071
ORF1ab/nsp14A2-B	74	I74I	atC	atT	2	2	AY.120	0.000074
ORF1ab/nsp14A2-B	74	I74I	atC	atT	2	2	AY.13	0.000322
ORF1ab/nsp14A2-B	74	I74del	ATC	---	2	2	AY.25	0.000012
ORF1ab/nsp14A2-B	74	I74I	atC	atT	2	2	AY.27	0.000129
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	2	2	AY.33	0.000134
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	2	2	AY.39	0.000049
ORF1ab/nsp14A2-B	74	I74I	atC	atA	1	2	AY.41	0.000294
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	2	AY.41	0.000294
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	2	2	AY.46	0.000208
ORF1ab/nsp14A2-B	74	I74I	atC	atT	2	2	AY.46	0.000208
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	2	2	AY.5	0.000041
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	2	2	AY.75	0.000112
ORF1ab/nsp14A2-B	74	I74G	ATC	GGG	1	2	AY.84	0.000437
ORF1ab/nsp14A2-B	74	I74G	ATC	GGT	1	2	AY.84	0.000437
ORF1ab/nsp14A2-B	74	I74V	AtC	GtG	1	2	AY.84	0.000437
ORF1ab/nsp14A2-B	74	I74V	AtC	GtT	1	2	AY.84	0.000437
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	2	2	AY.98	0.000158
ORF1ab/nsp14A2-B	74	I74I	atC	atT	2	2	AY.98.1	0.000097
ORF1ab/nsp14A2-B	74	I74G	ATC	GGT	1	2	AY.99	0.001049
ORF1ab/nsp14A2-B	74	I74G	ATC	GGG	1	2	AY.99	0.001049
ORF1ab/nsp14A2-B	74	I74F	Atc	Ttc	2	2	B.1	0.000018
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	2	2	B.1.1	0.000036
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	2	2	B.1.1.1	0.000653
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	2	2	B.1.1.241	0.004141
ORF1ab/nsp14A2-B	74	I74I	atC	atT	2	2	B.1.1.306	0.000877
ORF1ab/nsp14A2-B	74	I74I	atC	atT	2	2	B.1.1.311	0.000716
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	2	2	B.1.1.37	0.000386
ORF1ab/nsp14A2-B	74	I74N	aTc	aAc	2	2	B.1.1.52	0.02439
ORF1ab/nsp14A2-B	74	I74I	atC	atT	2	2	B.1.177.11	0.003396
ORF1ab/nsp14A2-B	74	I74I	atC	atT	2	2	B.1.232	0.001075
ORF1ab/nsp14A2-B	74	I74I	atC	atT	2	2	B.1.243	0.000139
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	2	2	B.1.258.12	0.015748
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	2	2	B.1.396	0.001411
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	2	2	B.1.409	0.001563
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	2	2	B.1.525	0.000226
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	2	2	B.1.526	0.000047
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	2	2	B.1.617.1	0.000258
ORF1ab/nsp14A2-B	74	I74S	aTc	aGc	2	2	B.1.617.2	0.000008
ORF1ab/nsp14A2-B	74	I74N	aTc	aAc	2	2	B.1.619	0.001742
ORF1ab/nsp14A2-B	74	I74I	atC	atT	2	2	C.37	0.000232
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	2	2	P.1.14	0.000096
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	2	2	P.1.14	0.000096
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	2	2	P.1.2	0.002312
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	2	2	P.2	0.000373
ORF1ab/nsp14A2-B	74	I74I	atC	atT	2	2	P.6	0.006289
ORF1ab/nsp14A2-B	74	I74I	atC	atT	2	2	Q.4	0.00091
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	2	2	Q.8	0.00033
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	2	2	R.1	0.00018
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1		0.055556
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	A	0.000387
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	A	0.000387
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	A.5	0.001923
ORF1ab/nsp14A2-B	74	I74C	ATC	TGT	1	1	All	0
ORF1ab/nsp14A2-B	74	I74R	aTC	aGG	1	1	All	0
ORF1ab/nsp14A2-B	74	I74del1	aTc	a-c	1	1	All	0
ORF1ab/nsp14A2-B	74	I74W	ATC	TGG	1	1	All	0
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	AY.100	0.000046
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	AY.102	0.000027
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	AY.103	0.000006
ORF1ab/nsp14A2-B	74	I74M	atC	atG	1	1	AY.103	0.000006
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	AY.105	0.000643
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.108	0.001103
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.109	0.00074
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.11	0.001339
ORF1ab/nsp14A2-B	74	I74del2	aTC	a--	1	1	AY.111	0.000183
ORF1ab/nsp14A2-B	74	I74M	atC	atG	1	1	AY.113	0.000142
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.114	0.000231
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	AY.117	0.000085
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	AY.118	0.000063
ORF1ab/nsp14A2-B	74	I74S	aTc	aGc	1	1	AY.119	0.000035
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	AY.120.2	0.001285
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	AY.120.2	0.001285
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.121	0.000135
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.2	0.000356
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.20	0.000039
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	AY.20	0.000039
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.21	0.001898
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	AY.24	0.000431
ORF1ab/nsp14A2-B	74	I74N	aTc	aAc	1	1	AY.3	0.00001
ORF1ab/nsp14A2-B	74	I74S	aTc	aGc	1	1	AY.3	0.00001
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.3.1	0.000085
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	AY.3.1	0.000085
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.33	0.000067
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	AY.34.1	0.00051
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	AY.36	0.000148
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	AY.38	0.000499
ORF1ab/nsp14A2-B	74	I74F	Atc	Ttc	1	1	AY.4	0.000002
ORF1ab/nsp14A2-B	74	I74del2	aTC	a--	1	1	AY.4	0.000002
ORF1ab/nsp14A2-B	74	I74del	ATC	---	1	1	AY.4	0.000002
ORF1ab/nsp14A2-B	74	I74N	aTc	aAc	1	1	AY.4	0.000002
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	AY.4.2	0.000022
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.4.2.1	0.000149
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.4.5	0.000107
ORF1ab/nsp14A2-B	74	I74S	aTc	aGc	1	1	AY.4.5	0.000107
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	AY.42	0.00004
ORF1ab/nsp14A2-B	74	I74del2	aTC	a--	1	1	AY.43	0.000004
ORF1ab/nsp14A2-B	74	I74N	aTc	aAc	1	1	AY.43	0.000004
ORF1ab/nsp14A2-B	74	I74N	aTc	aAc	1	1	AY.44	0.000006
ORF1ab/nsp14A2-B	74	I74S	aTc	aGc	1	1	AY.44	0.000006
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	AY.46	0.000104
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	AY.46.6	0.000072
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	AY.47	0.000031
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	AY.47	0.000031
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.48	0.000465
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.5.3	0.000337
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	AY.5.4	0.000277
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	AY.54	0.000095
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	AY.55	0.000917
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.55	0.000917
ORF1ab/nsp14A2-B	74	I74S	aTc	aGc	1	1	AY.6	0.000041
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.6	0.000041
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.61	0.000105
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	AY.61	0.000105
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	AY.65	0.000533
ORF1ab/nsp14A2-B	74	I74I	atC	atA	1	1	AY.67	0.000464
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	AY.7	0.000196
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	AY.75	0.000056
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.75.1	0.00018
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	AY.82	0.001357
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	AY.84	0.000437
ORF1ab/nsp14A2-B	74	I74M	atC	atG	1	1	AY.84	0.000437
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.84	0.000437
ORF1ab/nsp14A2-B	74	I74R	aTC	aGG	1	1	AY.84	0.000437
ORF1ab/nsp14A2-B	74	I74S	aTC	aGT	1	1	AY.84	0.000437
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.85	0.000427
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	AY.9.1	0.000084
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	AY.9.1	0.000084
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	AY.9.2	0.000037
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.92	0.000287
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	AY.98.1	0.000048
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	AY.98.1	0.000048
ORF1ab/nsp14A2-B	74	I74W	ATC	TGG	1	1	AY.99	0.001049
ORF1ab/nsp14A2-B	74	I74C	ATC	TGT	1	1	AY.99	0.001049
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	AY.99.2	0.000092
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	AY.99.2	0.000092
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	AZ.4	0.003356
ORF1ab/nsp14A2-B	74	I74N	aTc	aAc	1	1	B	0.000128
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	B	0.000128
ORF1ab/nsp14A2-B	74	I74M	atC	atG	1	1	B.1	0.000009
ORF1ab/nsp14A2-B	74	I74del	ATC	---	1	1	B.1	0.000009
ORF1ab/nsp14A2-B	74	I74N	aTc	aAc	1	1	B.1	0.000009
ORF1ab/nsp14A2-B	74	I74L	Atc	Ctc	1	1	B.1.1	0.000018
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	B.1.1.1	0.000327
ORF1ab/nsp14A2-B	74	I74I	atC	atA	1	1	B.1.1.1	0.000327
ORF1ab/nsp14A2-B	74	I74del	ATC	---	1	1	B.1.1.139	0.022727
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.1.207	0.001182
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.1.222	0.000204
ORF1ab/nsp14A2-B	74	I74S	aTc	aGc	1	1	B.1.1.231	0.003096
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.1.231	0.003096
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.1.265	0.003155
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	B.1.1.277	0.000759
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	B.1.1.291	0.000742
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	B.1.1.301	0.001179
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	B.1.1.372	0.000689
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.1.389	0.006061
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	B.1.1.389	0.006061
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.1.420	0.001006
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.1.434	0.000349
ORF1ab/nsp14A2-B	74	I74N	aTc	aAc	1	1	B.1.1.448	0.002033
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.1.50	0.000679
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	B.1.1.507	0.008696
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	B.1.1.51	0.001718
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.1.518	0.006329
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	B.1.1.55	0.012987
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	B.1.1.56	0.017857
ORF1ab/nsp14A2-B	74	I74L	Atc	Ctc	1	1	B.1.1.7	0.000001
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	B.1.1.70	0.000341
ORF1ab/nsp14A2-B	74	I74I	atC	atA	1	1	B.1.1.88	0.071429
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.110.3	0.000718
ORF1ab/nsp14A2-B	74	I74I	atC	atA	1	1	B.1.157	0.002985
ORF1ab/nsp14A2-B	74	I74S	aTc	aGc	1	1	B.1.160	0.000031
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	B.1.160	0.000031
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.160	0.000031
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.177.12	0.000152
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.177.21	0.000076
ORF1ab/nsp14A2-B	74	I74I	atC	atA	1	1	B.1.177.86	0.000183
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	B.1.177.86	0.000183
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.210	0.002132
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	B.1.210	0.002132
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	B.1.234	0.000132
ORF1ab/nsp14A2-B	74	I74del2	ATc	--c	1	1	B.1.258	0.000067
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	B.1.258	0.000067
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	B.1.258.14	0.00098
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	B.1.258.17	0.000104
ORF1ab/nsp14A2-B	74	I74I	atC	atA	1	1	B.1.260	0.003344
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	B.1.302	0.013333
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	B.1.311	0.000275
ORF1ab/nsp14A2-B	74	I74I	atC	atA	1	1	B.1.325	0.006897
ORF1ab/nsp14A2-B	74	I74M	atC	atG	1	1	B.1.351	0.00003
ORF1ab/nsp14A2-B	74	I74N	aTc	aAc	1	1	B.1.351	0.00003
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	B.1.36	0.000146
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	B.1.36.10	0.004785
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.36.17	0.000494
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	B.1.36.17	0.000494
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.36.19	0.009259
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.36.33	0.007576
ORF1ab/nsp14A2-B	74	I74del	ATC	---	1	1	B.1.415	0.014286
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	B.1.428	0.00102
ORF1ab/nsp14A2-B	74	I74S	aTc	aGc	1	1	B.1.432	0.011236
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	B.1.466.2	0.000391
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.466.2	0.000391
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	B.1.474	0.001901
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	B.1.495	0.009091
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	B.1.509	0.000866
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.511	0.034483
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	B.1.525	0.000113
ORF1ab/nsp14A2-B	74	I74del	ATC	---	1	1	B.1.561	0.000397
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	B.1.561	0.000397
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.574	0.002151
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	B.1.575	0.000303
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.609	0.000479
ORF1ab/nsp14A2-B	74	I74S	aTc	aGc	1	1	B.1.617.1	0.000129
ORF1ab/nsp14A2-B	74	I74del1	aTc	a-c	1	1	B.1.617.1	0.000129
ORF1ab/nsp14A2-B	74	I74del	ATC	---	1	1	B.1.617.2	0.000004
ORF1ab/nsp14A2-B	74	I74M	atC	atG	1	1	B.1.617.2	0.000004
ORF1ab/nsp14A2-B	74	I74S	aTc	aGc	1	1	B.1.620	0.000946
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.1.631	0.003367
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	B.1.637	0.000073
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.10	0.008264
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	B.6	0.00091
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	C.26	0.007353
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	C.37	0.000116
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	C.37	0.000116
ORF1ab/nsp14A2-B	74	I74F	Atc	Ttc	1	1	D.2	0.000075
ORF1ab/nsp14A2-B	74	I74S	aTc	aGc	1	1	D.2	0.000075
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	N.9	0.005952
ORF1ab/nsp14A2-B	74	I74N	aTc	aAc	1	1	P.1	0.000016
ORF1ab/nsp14A2-B	74	I74del	ATC	---	1	1	P.1	0.000016
ORF1ab/nsp14A2-B	74	I74T	aTc	aCc	1	1	P.1.15	0.000232
ORF1ab/nsp14A2-B	74	I74I	atC	atT	1	1	P.1.7	0.000319
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	Q.1	0.000126
ORF1ab/nsp14A2-B	74	I74del	ATC	---	1	1	Q.8	0.000165
ORF1ab/nsp14A2-B	74	I74V	Atc	Gtc	1	1	W.1	0.008696

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.