CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp14A2-B : CodonNum = 491

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF1ab/nsp14A2-B	491	Y491Y	Y6416Y	syn	taC	taT	4409	4409	1	19510-19512
ORF1ab/nsp14A2-B	491	Y491del	Y6416del	del	TAC	---	734	734	1	19510-19512
ORF1ab/nsp14A2-B	491	Y491G	Y6416G	nonsyn	TAc	GGc	64	63	0.984375	19510-19512
ORF1ab/nsp14A2-B	491	Y491G	Y6416G	nonsyn	TAC	GGT	64	1	0.015625	19510-19512
ORF1ab/nsp14A2-B	491	Y491H	Y6416H	nonsyn	Tac	Cac	50	50	1	19510-19512
ORF1ab/nsp14A2-B	491	Y491C	Y6416C	nonsyn	tAc	tGc	24	21	0.875	19510-19512
ORF1ab/nsp14A2-B	491	Y491C	Y6416C	nonsyn	tAC	tGT	24	3	0.125	19510-19512
ORF1ab/nsp14A2-B	491	Y491X	Y6416X	nonsyn	taC	taG	18	12	0.666667	19510-19512
ORF1ab/nsp14A2-B	491	Y491X	Y6416X	nonsyn	taC	taA	18	6	0.333333	19510-19512
ORF1ab/nsp14A2-B	491	Y491L	Y6416L	nonsyn	TAc	CTc	11	7	0.636364	19510-19512
ORF1ab/nsp14A2-B	491	Y491L	Y6416L	nonsyn	tAC	tTA	11	3	0.272727	19510-19512
ORF1ab/nsp14A2-B	491	Y491L	Y6416L	nonsyn	TAC	CTT	11	1	0.0909091	19510-19512
ORF1ab/nsp14A2-B	491	Y491F	Y6416F	nonsyn	tAc	tTc	7	7	1	19510-19512
ORF1ab/nsp14A2-B	491	Y491N	Y6416N	nonsyn	Tac	Aac	7	5	0.714286	19510-19512
ORF1ab/nsp14A2-B	491	Y491N	Y6416N	nonsyn	TaC	AaT	7	2	0.285714	19510-19512
ORF1ab/nsp14A2-B	491	Y491D	Y6416D	nonsyn	Tac	Gac	6	6	1	19510-19512
ORF1ab/nsp14A2-B	491	Y491S	Y6416S	nonsyn	tAc	tCc	5	5	1	19510-19512
ORF1ab/nsp14A2-B	491	Y491V	Y6416V	nonsyn	TAc	GTc	2	1	0.5	19510-19512
ORF1ab/nsp14A2-B	491	Y491V	Y6416V	nonsyn	TAC	GTA	2	1	0.5	19510-19512
ORF1ab/nsp14A2-B	491	Y491del2	Y6416del2	del	tAC	t--	2	1	0.5	19510-19512
ORF1ab/nsp14A2-B	491	Y491R	Y6416R	nonsyn	TAC	CGT	2	1	0.5	19510-19512
ORF1ab/nsp14A2-B	491	Y491R	Y6416R	nonsyn	TAc	CGc	2	1	0.5	19510-19512
ORF1ab/nsp14A2-B	491	Y491del2	Y6416del2	del	TAC	--N	2	1	0.5	19510-19512
ORF1ab/nsp14A2-B	491	Y491K	Y6416K	nonsyn	TaC	AaA	1	1	1	19510-19512
ORF1ab/nsp14A2-B	491	Y491W	Y6416W	nonsyn	tAC	tGG	1	1	1	19510-19512
ORF1ab/nsp14A2-B	491	Y491del1	Y6416del1	del	Tac	-ac	1	1	1	19510-19512
ORF1ab/nsp14A2-B	491	Y491Q	Y6416Q	nonsyn	TaC	CaG	1	1	1	19510-19512
ORF1ab/nsp14A2-B	491	Y491A	Y6416A	nonsyn	TAc	GCc	1	1	1	19510-19512
ORF1ab/nsp14A2-B	491	Y491E	Y6416E	nonsyn	TaC	GaA	1	1	1	19510-19512

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	4409	4409	All	0.000843
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1655	1655	B.1.36.36	0.996388
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	983	983	B.1.2	0.008656
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	734	734	All	0.00014
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	460	460	AY.4	0.000716
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	378	378	B.1.1.7	0.000338
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	154	154	AY.43	0.000682
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	115	115	AY.25	0.000692
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	85	85	B.1.617.2	0.00032
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	76	76	B.1.2	0.000669
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	71	71	AY.43	0.000315
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	63	64	All	0.000012
ORF1ab/nsp14A2-B	491	Y491G	TAC	GGT	1	64	All	0
ORF1ab/nsp14A2-B	491	Y491H	Tac	Cac	50	50	All	0.00001
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	48	48	C.37	0.005571
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	46	46	B.1.617.2	0.000173
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	44	44	B.1.1.7	0.000039
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	44	44	B.1.612	0.116711
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	40	40	AY.103	0.000248
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	35	35	AY.25	0.000211
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	30	30	B.1	0.000275
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	29	29	AY.44	0.000177
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	28	28	B.1	0.000256
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	27	27	B.1.160	0.000842
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	26	26	AY.3	0.000259
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	25	25	AY.39	0.000618
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	25	25	B.1.177	0.000329
ORF1ab/nsp14A2-B	491	Y491C	tAc	tGc	21	24	All	0.000004
ORF1ab/nsp14A2-B	491	Y491C	tAC	tGT	3	24	All	0.000001
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	24	24	B.1.1	0.000435
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	23	23	B.1.617.2	0.000087
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	20	20	AY.44	0.000122
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	20	20	B.1.279	0.010272
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	19	19	AY.34.1	0.009689
ORF1ab/nsp14A2-B	491	Y491X	taC	taG	12	18	All	0.000002
ORF1ab/nsp14A2-B	491	Y491X	taC	taA	6	18	All	0.000001
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	18	18	B.1.36	0.002626
ORF1ab/nsp14A2-B	491	Y491H	Tac	Cac	17	17	B.1.617.2	0.000064
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	15	15	AY.3	0.000149
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	15	15	B.1.526	0.000353
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	14	14	P.1	0.000221
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	13	13	B.1.526	0.000306
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	12	12	B.1.1	0.000218
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	12	12	B.1.351	0.000357
ORF1ab/nsp14A2-B	491	Y491L	TAc	CTc	7	11	All	0.000001
ORF1ab/nsp14A2-B	491	Y491L	tAC	tTA	3	11	All	0.000001
ORF1ab/nsp14A2-B	491	Y491L	TAC	CTT	1	11	All	0
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	11	11	AY.103	0.000068
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	11	11	AY.29	0.000174
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	11	11	AY.39	0.000272
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	11	11	Q.8	0.001814
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	10	10	AY.9.2	0.000367
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	9	9	AY.102	0.000239
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	9	9	AY.75	0.000504
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	9	9	B.1	0.000082
ORF1ab/nsp14A2-B	491	Y491C	tAc	tGc	9	9	B.1.1.7	0.000008
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	8	8	AY.102	0.000212
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	8	8	AY.52	0.006515
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	8	8	AY.98.1	0.000387
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	8	8	B.1.1.28	0.00249
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	8	8	B.1.596	0.000697
ORF1ab/nsp14A2-B	491	Y491F	tAc	tTc	7	7	All	0.000001
ORF1ab/nsp14A2-B	491	Y491N	Tac	Aac	5	7	All	0.000001
ORF1ab/nsp14A2-B	491	Y491N	TaC	AaT	2	7	All	0
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	7	7	AY.38	0.003495
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	7	7	AY.4	0.000011
ORF1ab/nsp14A2-B	491	Y491H	Tac	Cac	7	7	B.1.1.7	0.000006
ORF1ab/nsp14A2-B	491	Y491H	Tac	Cac	7	7	B.1.234	0.000924
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	7	7	B.1.429	0.000165
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	7	7	P.1.14	0.000335
ORF1ab/nsp14A2-B	491	Y491D	Tac	Gac	6	6	All	0.000001
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	6	6	AY.118	0.000376
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	6	6	AY.24	0.002586
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	6	6	AY.42	0.000241
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	6	6	AY.46.5	0.00119
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	6	6	B.1.1.214	0.000333
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	6	6	B.1.1.33	0.002525
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	6	6	B.1.170	0.025862
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	6	6	B.1.221	0.000426
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	6	6	B.1.258.4	0.02069
ORF1ab/nsp14A2-B	491	Y491S	tAc	tCc	5	5	All	0.000001
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	5	5	AY.119	0.000177
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	5	5	AY.42	0.000201
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	5	5	B.1.177	0.000066
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	5	5	B.1.243	0.000348
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	5	5	B.1.628	0.001762
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	4	4		0.222222
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	4	4	AY.100	0.000184
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	4	4	AY.11	0.005355
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	4	4	AY.110	0.000451
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	4	4	AY.23	0.000279
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	4	4	AY.33	0.000267
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	4	4	AY.4.2	0.000087
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	4	4	AY.65	0.002132
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	4	4	AY.74	0.000463
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	4	4	AY.75	0.000224
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	4	4	B.1.1.222	0.000816
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	4	4	B.1.1.519	0.000159
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	4	4	B.1.36	0.000584
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	4	4	B.1.427	0.000202
ORF1ab/nsp14A2-B	491	Y491X	taC	taG	4	4	B.1.429	0.000094
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	4	4	B.1.617.1	0.000516
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	3	3	A.28	0.007937
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	3	3	AY.100	0.000138
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	3	3	AY.3.1	0.000256
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	3	3	AY.33	0.0002
ORF1ab/nsp14A2-B	491	Y491C	tAc	tGc	2	3	AY.43	0.000009
ORF1ab/nsp14A2-B	491	Y491L	TAc	CTc	2	3	AY.43	0.000009
ORF1ab/nsp14A2-B	491	Y491C	tAC	tGT	1	3	AY.43	0.000004
ORF1ab/nsp14A2-B	491	Y491L	TAC	CTT	1	3	AY.43	0.000004
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	3	3	AY.64	0.001786
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	3	3	AY.65	0.001599
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	3	3	AY.9	0.000203
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	3	3	B.1.1.218	0.023077
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	3	3	B.1.1.416	0.002715
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	3	3	B.1.1.7	0.000003
ORF1ab/nsp14A2-B	491	Y491X	taC	taA	2	3	B.1.1.7	0.000002
ORF1ab/nsp14A2-B	491	Y491X	taC	taG	1	3	B.1.1.7	0.000001
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	3	3	B.1.177.21	0.000229
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	3	3	B.1.177.86	0.00055
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	3	3	B.1.265	0.003812
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	3	3	B.1.429	0.000071
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	3	3	B.1.621	0.000266
ORF1ab/nsp14A2-B	491	Y491N	TaC	AaT	2	2		0.111111
ORF1ab/nsp14A2-B	491	Y491H	Tac	Cac	2	2		0.111111
ORF1ab/nsp14A2-B	491	Y491V	TAc	GTc	1	2		0.055556
ORF1ab/nsp14A2-B	491	Y491V	TAC	GTA	1	2		0.055556
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	A.2	0.001324
ORF1ab/nsp14A2-B	491	Y491V	TAC	GTA	1	2	All	0
ORF1ab/nsp14A2-B	491	Y491V	TAc	GTc	1	2	All	0
ORF1ab/nsp14A2-B	491	Y491R	TAc	CGc	1	2	All	0
ORF1ab/nsp14A2-B	491	Y491del2	tAC	t--	1	2	All	0
ORF1ab/nsp14A2-B	491	Y491del2	TAC	--N	1	2	All	0
ORF1ab/nsp14A2-B	491	Y491R	TAC	CGT	1	2	All	0
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	AY.101	0.000981
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	AY.107	0.000932
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	AY.119	0.000071
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	AY.120	0.000074
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	AY.14	0.000176
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	AY.20	0.000078
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	AY.20	0.000078
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	AY.26	0.000057
ORF1ab/nsp14A2-B	491	Y491R	TAC	CGT	1	2	AY.3	0.00001
ORF1ab/nsp14A2-B	491	Y491R	TAc	CGc	1	2	AY.3	0.00001
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	AY.4.2.1	0.000298
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	2	2	AY.40	0.001929
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	2	2	AY.43	0.000009
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	2	2	AY.44	0.000012
ORF1ab/nsp14A2-B	491	Y491H	Tac	Cac	2	2	AY.44	0.000012
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	AY.45	0.000243
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	AY.47	0.000062
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	AY.5.3	0.000675
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	AY.5.4	0.000553
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	2	2	AY.52	0.001629
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	AY.55	0.001835
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	AY.59	0.001059
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	AY.7.2	0.001119
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	AY.71	0.00095
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	2	2	AY.75	0.000112
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	AY.75.1	0.000361
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	AY.85	0.000854
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	AY.9.1	0.000167
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	2	2	AY.9.2	0.000073
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	AY.9.2	0.000073
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	AY.97	0.003401
ORF1ab/nsp14A2-B	491	Y491H	Tac	Cac	2	2	AY.98	0.000158
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	AY.99.2	0.000184
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	AY.99.2	0.000184
ORF1ab/nsp14A2-B	491	Y491C	tAc	tGc	2	2	B.1	0.000018
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	B.1.1.266	0.02439
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	B.1.1.277	0.001517
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	B.1.1.46	0.008734
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	B.1.1.464	0.002946
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	B.1.1.519	0.000079
ORF1ab/nsp14A2-B	491	Y491F	tAc	tTc	2	2	B.1.1.7	0.000002
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	B.1.160	0.000062
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	B.1.177.81	0.000379
ORF1ab/nsp14A2-B	491	Y491X	taC	taA	1	2	B.1.2	0.000009
ORF1ab/nsp14A2-B	491	Y491X	taC	taG	1	2	B.1.2	0.000009
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	B.1.221	0.000142
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	B.1.234	0.000264
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	B.1.243	0.000139
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	B.1.258	0.000133
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	B.1.311	0.000549
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	B.1.349	0.00143
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	B.1.39	0.007812
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	B.1.397	0.009709
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	B.1.453	0.006472
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	B.1.517	0.000854
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	B.1.568	0.002222
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	B.1.588	0.00182
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	B.1.595	0.000522
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	B.1.596	0.000174
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	B.1.617.1	0.000258
ORF1ab/nsp14A2-B	491	Y491C	tAc	tGc	2	2	B.1.617.2	0.000008
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	2	2	B.1.637	0.000146
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	P.1	0.000032
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	2	2	P.1.15	0.000465
ORF1ab/nsp14A2-B	491	Y491L	tAC	tTA	1	1		0.055556
ORF1ab/nsp14A2-B	491	Y491X	taC	taA	1	1		0.055556
ORF1ab/nsp14A2-B	491	Y491E	TaC	GaA	1	1		0.055556
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1		0.055556
ORF1ab/nsp14A2-B	491	Y491D	Tac	Gac	1	1		0.055556
ORF1ab/nsp14A2-B	491	Y491F	tAc	tTc	1	1		0.055556
ORF1ab/nsp14A2-B	491	Y491F	tAc	tTc	1	1	A.2.4	0.003367
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	A.2.4	0.003367
ORF1ab/nsp14A2-B	491	Y491D	Tac	Gac	1	1	A.2.4	0.003367
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	A.2.5	0.000499
ORF1ab/nsp14A2-B	491	Y491E	TaC	GaA	1	1	All	0
ORF1ab/nsp14A2-B	491	Y491A	TAc	GCc	1	1	All	0
ORF1ab/nsp14A2-B	491	Y491K	TaC	AaA	1	1	All	0
ORF1ab/nsp14A2-B	491	Y491W	tAC	tGG	1	1	All	0
ORF1ab/nsp14A2-B	491	Y491del1	Tac	-ac	1	1	All	0
ORF1ab/nsp14A2-B	491	Y491Q	TaC	CaG	1	1	All	0
ORF1ab/nsp14A2-B	491	Y491X	taC	taG	1	1	AU.2	0.002421
ORF1ab/nsp14A2-B	491	Y491D	Tac	Gac	1	1	AY.102	0.000027
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	1	1	AY.102	0.000027
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	AY.105	0.000643
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	1	1	AY.106	0.000335
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	AY.106	0.000335
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	AY.108	0.001103
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.109	0.00074
ORF1ab/nsp14A2-B	491	Y491L	TAc	CTc	1	1	AY.110	0.000113
ORF1ab/nsp14A2-B	491	Y491C	tAc	tGc	1	1	AY.113	0.000142
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	AY.113	0.000142
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	AY.116	0.000287
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.117	0.000085
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.12	0.000316
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	1	1	AY.120	0.000037
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.120	0.000037
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	AY.120.2	0.001285
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	AY.13	0.000161
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.13	0.000161
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	1	1	AY.13	0.000161
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	AY.16.1	0.00047
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	1	1	AY.16.1	0.00047
ORF1ab/nsp14A2-B	491	Y491N	Tac	Aac	1	1	AY.20	0.000039
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	AY.21	0.001898
ORF1ab/nsp14A2-B	491	Y491N	Tac	Aac	1	1	AY.23	0.00007
ORF1ab/nsp14A2-B	491	Y491H	Tac	Cac	1	1	AY.23	0.00007
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.23	0.00007
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.23.1	0.000417
ORF1ab/nsp14A2-B	491	Y491G	TAC	GGT	1	1	AY.25	0.000006
ORF1ab/nsp14A2-B	491	Y491C	tAC	tGT	1	1	AY.3	0.00001
ORF1ab/nsp14A2-B	491	Y491L	TAc	CTc	1	1	AY.3	0.00001
ORF1ab/nsp14A2-B	491	Y491W	tAC	tGG	1	1	AY.3	0.00001
ORF1ab/nsp14A2-B	491	Y491H	Tac	Cac	1	1	AY.3	0.00001
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.3.1	0.000085
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.30	0.000396
ORF1ab/nsp14A2-B	491	Y491X	taC	taA	1	1	AY.33	0.000067
ORF1ab/nsp14A2-B	491	Y491H	Tac	Cac	1	1	AY.33	0.000067
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.36	0.000148
ORF1ab/nsp14A2-B	491	Y491S	tAc	tCc	1	1	AY.39.2	0.001541
ORF1ab/nsp14A2-B	491	Y491F	tAc	tTc	1	1	AY.4	0.000002
ORF1ab/nsp14A2-B	491	Y491C	tAc	tGc	1	1	AY.4	0.000002
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	AY.4.2	0.000022
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.4.5	0.000107
ORF1ab/nsp14A2-B	491	Y491K	TaC	AaA	1	1	AY.43	0.000004
ORF1ab/nsp14A2-B	491	Y491H	Tac	Cac	1	1	AY.43	0.000004
ORF1ab/nsp14A2-B	491	Y491S	tAc	tCc	1	1	AY.43	0.000004
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	AY.46	0.000104
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.46.2	0.000635
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	AY.46.2	0.000635
ORF1ab/nsp14A2-B	491	Y491L	TAc	CTc	1	1	AY.46.6	0.000072
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	AY.46.6	0.000072
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.48	0.000465
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.5	0.000021
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	1	1	AY.5.3	0.000337
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.5.3	0.000337
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	AY.53	0.000288
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	AY.54	0.000095
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.55	0.000917
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	AY.59	0.00053
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.61	0.000105
ORF1ab/nsp14A2-B	491	Y491S	tAc	tCc	1	1	AY.61	0.000105
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	AY.62	0.000436
ORF1ab/nsp14A2-B	491	Y491C	tAC	tGT	1	1	AY.67	0.000464
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.7	0.000196
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.7.1	0.000113
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	AY.7.2	0.000559
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.70	0.000209
ORF1ab/nsp14A2-B	491	Y491H	Tac	Cac	1	1	AY.75	0.000056
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	1	1	AY.75.1	0.00018
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.75.1	0.00018
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	AY.78	0.001541
ORF1ab/nsp14A2-B	491	Y491D	Tac	Gac	1	1	AY.79	0.001211
ORF1ab/nsp14A2-B	491	Y491A	TAc	GCc	1	1	AY.79	0.001211
ORF1ab/nsp14A2-B	491	Y491S	tAc	tCc	1	1	AY.79	0.001211
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.84	0.000437
ORF1ab/nsp14A2-B	491	Y491L	TAc	CTc	1	1	AY.84	0.000437
ORF1ab/nsp14A2-B	491	Y491L	TAc	CTc	1	1	AY.9.2	0.000037
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.90	0.000684
ORF1ab/nsp14A2-B	491	Y491H	Tac	Cac	1	1	AY.93	0.000273
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	AY.94	0.000443
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.94	0.000443
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	AY.99	0.001049
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	AY.99	0.001049
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B	0.000128
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	1	1	B	0.000128
ORF1ab/nsp14A2-B	491	Y491X	taC	taG	1	1	B.1	0.000009
ORF1ab/nsp14A2-B	491	Y491F	tAc	tTc	1	1	B.1	0.000009
ORF1ab/nsp14A2-B	491	Y491D	Tac	Gac	1	1	B.1.1	0.000018
ORF1ab/nsp14A2-B	491	Y491N	Tac	Aac	1	1	B.1.1	0.000018
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	1	1	B.1.1	0.000018
ORF1ab/nsp14A2-B	491	Y491H	Tac	Cac	1	1	B.1.1	0.000018
ORF1ab/nsp14A2-B	491	Y491L	tAC	tTA	1	1	B.1.1	0.000018
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.1.144	0.028571
ORF1ab/nsp14A2-B	491	Y491del2	tAC	t--	1	1	B.1.1.158	0.012195
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.1.174	0.003378
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.1.192	0.002309
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.1.194	0.00495
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.1.207	0.001182
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.1.243	0.004082
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.1.306	0.000438
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.1.335	0.012987
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.1.348	0.000796
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.1.37	0.000193
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.1.409	0.002833
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.1.411	0.014706
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.1.411	0.014706
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.1.413	0.006897
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.1.434	0.000349
ORF1ab/nsp14A2-B	491	Y491N	Tac	Aac	1	1	B.1.1.434	0.000349
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.1.448	0.002033
ORF1ab/nsp14A2-B	491	Y491F	tAc	tTc	1	1	B.1.1.519	0.00004
ORF1ab/nsp14A2-B	491	Y491C	tAc	tGc	1	1	B.1.1.519	0.00004
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.1.523	0.001563
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.1.526	0.003546
ORF1ab/nsp14A2-B	491	Y491L	tAC	tTA	1	1	B.1.1.7	0.000001
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.1.70	0.000341
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.110.3	0.000718
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.147	0.000756
ORF1ab/nsp14A2-B	491	Y491C	tAc	tGc	1	1	B.1.160	0.000031
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.160.16	0.000929
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.177.12	0.000152
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.177.17	0.000821
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.177.18	0.00116
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.177.44	0.000519
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.177.50	0.004695
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.177.51	0.004566
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.177.62	0.001192
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.177.68	0.015152
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	1	1	B.1.177.73	0.000566
ORF1ab/nsp14A2-B	491	Y491H	Tac	Cac	1	1	B.1.2	0.000009
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.206	0.000816
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.232	0.000537
ORF1ab/nsp14A2-B	491	Y491X	taC	taG	1	1	B.1.239	0.001221
ORF1ab/nsp14A2-B	491	Y491del2	TAC	--N	1	1	B.1.243	0.00007
ORF1ab/nsp14A2-B	491	Y491H	Tac	Cac	1	1	B.1.243	0.00007
ORF1ab/nsp14A2-B	491	Y491X	taC	taG	1	1	B.1.243	0.00007
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.258	0.000067
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.291	0.019231
ORF1ab/nsp14A2-B	491	Y491C	tAc	tGc	1	1	B.1.311	0.000275
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.324	0.001605
ORF1ab/nsp14A2-B	491	Y491H	Tac	Cac	1	1	B.1.351	0.00003
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.351	0.00003
ORF1ab/nsp14A2-B	491	Y491H	Tac	Cac	1	1	B.1.351.3	0.000876
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.36.1	0.00114
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.36.31	0.001751
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.36.35	0.002604
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	1	1	B.1.36.8	0.001
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.36.8	0.001
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.395	0.007042
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.404	0.001302
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.409	0.000781
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.416.1	0.001563
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.422	0.000812
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.427	0.00005
ORF1ab/nsp14A2-B	491	Y491X	taC	taG	1	1	B.1.427	0.00005
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.438.1	0.000107
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.439	0.005917
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.471	0.002732
ORF1ab/nsp14A2-B	491	Y491X	taC	taA	1	1	B.1.497	0.000315
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.517	0.000427
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.527	0.003704
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.551	0.00129
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.561	0.000397
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.574	0.002151
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.575	0.000303
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	B.1.576	0.000907
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	1	1	B.1.576	0.000907
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.1.590	0.004545
ORF1ab/nsp14A2-B	491	Y491G	TAc	GGc	1	1	B.1.617.1	0.000129
ORF1ab/nsp14A2-B	491	Y491H	Tac	Cac	1	1	B.1.617.1	0.000129
ORF1ab/nsp14A2-B	491	Y491D	Tac	Gac	1	1	B.1.617.2	0.000004
ORF1ab/nsp14A2-B	491	Y491Q	TaC	CaG	1	1	B.1.617.2	0.000004
ORF1ab/nsp14A2-B	491	Y491S	tAc	tCc	1	1	B.1.617.2	0.000004
ORF1ab/nsp14A2-B	491	Y491X	taC	taG	1	1	B.1.619.1	0.000641
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.4	0.002208
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	B.6	0.00091
ORF1ab/nsp14A2-B	491	Y491C	tAc	tGc	1	1	B.6.6	0.000889
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	C.1.2	0.004255
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	C.37	0.000116
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	C.37.1	0.002618
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	C.5	0.090909
ORF1ab/nsp14A2-B	491	Y491H	Tac	Cac	1	1	D.2	0.000075
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	D.2	0.000075
ORF1ab/nsp14A2-B	491	Y491del1	Tac	-ac	1	1	P.1.14	0.000048
ORF1ab/nsp14A2-B	491	Y491N	Tac	Aac	1	1	P.1.14	0.000048
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	P.1.15	0.000232
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	P.3	0.001595
ORF1ab/nsp14A2-B	491	Y491del	TAC	---	1	1	Q.1	0.000126
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	Q.1	0.000126
ORF1ab/nsp14A2-B	491	Y491Y	taC	taT	1	1	R.1	0.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.