CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp14A2-B : CodonNum = 327 & Codon = cTa

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp14A2-B327P327LP6252LnonsyncCacTa324232400.99938319018-19020

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp14A2-B327P327LcCacTa32403242All0.00062
ORF1ab/nsp14A2-B327P327LcCacTa19101910AY.40.002973
ORF1ab/nsp14A2-B327P327LcCacTa828829B.1.1.70.000741
ORF1ab/nsp14A2-B327P327LcCacTa9797AY.430.00043
ORF1ab/nsp14A2-B327P327LcCacTa6868B.1.617.20.000256
ORF1ab/nsp14A2-B327P327LcCacTa3939Q.80.006431
ORF1ab/nsp14A2-B327P327LcCacTa2626AY.1020.000689
ORF1ab/nsp14A2-B327P327LcCacTa1919B.1.1.2850.124183
ORF1ab/nsp14A2-B327P327LcCacTa1818AY.390.000445
ORF1ab/nsp14A2-B327P327LcCacTa1717B.1.20.00015
ORF1ab/nsp14A2-B327P327LcCacTa1515AY.1030.000093
ORF1ab/nsp14A2-B327P327LcCacTa1212AY.440.000073
ORF1ab/nsp14A2-B327P327LcCacTa1212B.10.00011
ORF1ab/nsp14A2-B327P327LcCacTa1111AY.250.000066
ORF1ab/nsp14A2-B327P327LcCacTa1111B.1.5960.000959
ORF1ab/nsp14A2-B327P327LcCacTa1010B.1.1.1760.004394
ORF1ab/nsp14A2-B327P327LcCacTa1010B.1.2580.000665
ORF1ab/nsp14A2-B327P327LcCacTa99B.1.2060.007341
ORF1ab/nsp14A2-B327P327LcCacTa55AY.30.00005
ORF1ab/nsp14A2-B327P327LcCacTa55P.10.000079
ORF1ab/nsp14A2-B327P327LcCacTa44AY.1170.000338
ORF1ab/nsp14A2-B327P327LcCacTa44AY.1200.000149
ORF1ab/nsp14A2-B327P327LcCacTa44AY.4.20.000087
ORF1ab/nsp14A2-B327P327LcCacTa44B.1.1.2160.003562
ORF1ab/nsp14A2-B327P327LcCacTa44B.1.1.2410.008282
ORF1ab/nsp14A2-B327P327LcCacTa44B.1.2340.000528
ORF1ab/nsp14A2-B327P327LcCacTa33AY.130.000483
ORF1ab/nsp14A2-B327P327LcCacTa33AY.200.000117
ORF1ab/nsp14A2-B327P327LcCacTa33AY.420.000121
ORF1ab/nsp14A2-B327P327LcCacTa33AY.650.001599
ORF1ab/nsp14A2-B327P327LcCacTa33AY.920.000862
ORF1ab/nsp14A2-B327P327LcCacTa33B.1.10.000054
ORF1ab/nsp14A2-B327P327LcCacTa33P.1.140.000143
ORF1ab/nsp14A2-B327P327LcCacTa22AY.1210.000271
ORF1ab/nsp14A2-B327P327LcCacTa22AY.4.50.000215
ORF1ab/nsp14A2-B327P327LcCacTa22AY.540.000191
ORF1ab/nsp14A2-B327P327LcCacTa22B.1.1.2910.001485
ORF1ab/nsp14A2-B327P327LcCacTa22B.1.160.140.004237
ORF1ab/nsp14A2-B327P327LcCacTa22B.1.36.170.000988
ORF1ab/nsp14A2-B327P327LcCacTa22B.1.4270.000101
ORF1ab/nsp14A2-B327P327LcCacTa22C.360.001821
ORF1ab/nsp14A2-B327P327LcCacTa22C.370.000232
ORF1ab/nsp14A2-B327P327LcCacTa22D.20.00015
ORF1ab/nsp14A2-B327P327LcCacTa22P.1.20.002312
ORF1ab/nsp14A2-B327P327LcCacTa22Q.10.000253
ORF1ab/nsp14A2-B327P327LcCacTa11A0.000387
ORF1ab/nsp14A2-B327P327LcCacTa11A.2.50.000499
ORF1ab/nsp14A2-B327P327LcCacTa11AY.1050.000643
ORF1ab/nsp14A2-B327P327LcCacTa11AY.1160.000287
ORF1ab/nsp14A2-B327P327LcCacTa11AY.1190.000035
ORF1ab/nsp14A2-B327P327LcCacTa11AY.230.00007
ORF1ab/nsp14A2-B327P327LcCacTa11AY.270.000065
ORF1ab/nsp14A2-B327P327LcCacTa11AY.3.10.000085
ORF1ab/nsp14A2-B327P327LcCacTa11AY.360.000148
ORF1ab/nsp14A2-B327P327LcCacTa11AY.39.10.00004
ORF1ab/nsp14A2-B327P327LcCacTa11AY.450.000122
ORF1ab/nsp14A2-B327P327LcCacTa11AY.46.60.000072
ORF1ab/nsp14A2-B327P327LcCacTa11AY.50.000021
ORF1ab/nsp14A2-B327P327LcCacTa11AY.550.000917
ORF1ab/nsp14A2-B327P327LcCacTa11AY.60.000041
ORF1ab/nsp14A2-B327P327LcCacTa11AY.70.000196
ORF1ab/nsp14A2-B327P327LcCacTa11AY.750.000056
ORF1ab/nsp14A2-B327P327LcCacTa11AY.850.000427
ORF1ab/nsp14A2-B327P327LcCacTa11AY.9.10.000084
ORF1ab/nsp14A2-B327P327LcCacTa11AY.98.10.000048
ORF1ab/nsp14A2-B327P327LcCacTa11AY.99.20.000092
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.1.290.010309
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.1.3060.000438
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.1.330.000421
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.1.3720.000689
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.1.3910.008547
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.1.4160.000905
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.1.4870.005587
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.1.5250.005464
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.1.700.000341
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.1600.000031
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.1770.000013
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.177.40.000211
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.177.410.0025
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.177.730.000566
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.177.810.000189
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.3460.001311
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.3480.018182
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.3510.00003
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.3690.000285
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.3890.001002
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.4290.000024
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.438.10.000107
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.4560.003268
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.466.20.000391
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.5260.000024
ORF1ab/nsp14A2-B327P327LcCacTa11B.1.6090.000479
ORF1ab/nsp14A2-B327P327LcCacTa11C.170.055556
ORF1ab/nsp14A2-B327P327LcCacTa11P.20.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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