CoV-GLUE | Mutations | Mutation
CoV-GLUE Mutation: ORF = ORF1ab/nsp14A2-B : CodonNum = 222 & Codon = gaT
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
| ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
| ORF1ab/nsp14A2-B | 222 | D222D | D6147D | syn | gaC | gaT | 1708 | 1708 | 1 | 18703-18705 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
| ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1708 | 1708 | All | 0.000327 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 847 | 847 | B.1.1.7 | 0.000758 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 237 | 237 | AY.25 | 0.001426 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 69 | 69 | AY.4 | 0.000107 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 64 | 64 | AY.43 | 0.000284 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 54 | 54 | AY.6 | 0.002221 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 45 | 45 | AY.5 | 0.000929 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 32 | 32 | B.1.617.2 | 0.00012 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 22 | 22 | AY.44 | 0.000134 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 21 | 21 | AY.103 | 0.00013 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 18 | 18 | B.1.575 | 0.005461 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 17 | 17 | P.1 | 0.000268 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 15 | 15 | B.1 | 0.000137 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 15 | 15 | B.1.2 | 0.000132 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 12 | 12 | C.37 | 0.001393 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 9 | 9 | AY.74 | 0.001041 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 9 | 9 | B.1.1 | 0.000163 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 8 | 8 | B.1.1.192 | 0.018476 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 8 | 8 | P.1.15 | 0.001859 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 7 | 7 | AY.3 | 0.00007 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 7 | 7 | B.1.160 | 0.000218 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 7 | 7 | B.1.351.2 | 0.002118 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 7 | 7 | B.1.526 | 0.000165 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 6 | 6 | AY.100 | 0.000276 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 6 | 6 | AY.26 | 0.00017 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 6 | 6 | AY.33 | 0.000401 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 6 | 6 | AY.47 | 0.000187 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 6 | 6 | B.1.177 | 0.000079 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 5 | 5 | B.1.1.157 | 0.004566 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 5 | 5 | B.1.1.306 | 0.002192 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 5 | 5 | B.1.177.4 | 0.001055 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 5 | 5 | B.1.36.8 | 0.005 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 5 | 5 | B.1.471 | 0.013661 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 4 | 4 | A.2.5.3 | 0.041237 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 4 | 4 | AY.120 | 0.000149 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 4 | 4 | AY.39 | 0.000099 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 4 | 4 | AY.42 | 0.000161 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 4 | 4 | AY.99.2 | 0.000369 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 4 | 4 | B.1.497 | 0.001259 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 3 | 3 | AY.114 | 0.000693 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 3 | 3 | AY.16 | 0.001139 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 3 | 3 | B.1.1.519 | 0.000119 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 3 | 3 | B.1.177.63 | 0.008108 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 3 | 3 | B.1.258 | 0.0002 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 3 | 3 | B.1.351 | 0.000089 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 3 | 3 | B.1.427 | 0.000151 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 3 | 3 | B.1.429 | 0.000071 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 2 | 2 | A.2.5 | 0.000998 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 2 | 2 | AY.46 | 0.000208 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 2 | 2 | AY.46.6 | 0.000144 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 2 | 2 | B.1.1.189 | 0.003026 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 2 | 2 | B.1.1.25 | 0.001137 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 2 | 2 | B.1.1.285 | 0.013072 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 2 | 2 | B.1.1.317 | 0.000823 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 2 | 2 | B.1.177.81 | 0.000379 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 2 | 2 | B.1.206 | 0.001631 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 2 | 2 | B.1.36 | 0.000292 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 2 | 2 | B.1.361 | 0.002577 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 2 | 2 | B.1.456 | 0.006536 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 2 | 2 | B.1.621 | 0.000177 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 2 | 2 | B.1.637 | 0.000146 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 2 | 2 | P.1.14 | 0.000096 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 2 | 2 | P.1.7 | 0.000639 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | A.2 | 0.000662 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | AY.1 | 0.000396 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | AY.102 | 0.000027 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | AY.108 | 0.001103 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | AY.110 | 0.000113 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | AY.117 | 0.000085 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | AY.119 | 0.000035 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | AY.20 | 0.000039 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | AY.23 | 0.00007 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | AY.24 | 0.000431 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | AY.32 | 0.000532 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | AY.36 | 0.000148 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | AY.45 | 0.000122 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | AY.5.4 | 0.000277 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | AY.53 | 0.000288 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | AY.62 | 0.000436 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | AY.63 | 0.000387 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | AY.68 | 0.000274 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | AY.7 | 0.000196 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | AY.9.2.1 | 0.001976 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | B.1.1.222 | 0.000204 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | B.1.1.286 | 0.002899 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | B.1.160.17 | 0.001701 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | B.1.177.32 | 0.00135 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | B.1.177.57 | 0.000281 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | B.1.177.6 | 0.000977 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | B.1.177.79 | 0.002342 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | B.1.221 | 0.000071 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | B.1.240 | 0.000216 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | B.1.258.17 | 0.000104 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | B.1.36.36 | 0.000602 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | B.1.396 | 0.000706 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | B.1.438.1 | 0.000107 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | B.1.453 | 0.003236 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | B.1.480 | 0.002488 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | B.1.525 | 0.000113 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | B.1.574 | 0.002151 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | B.1.617.1 | 0.000129 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | C.36.3 | 0.000567 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | P.1.2 | 0.001156 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | Q.2 | 0.000613 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | Q.3 | 0.000145 |
| ORF1ab/nsp14A2-B | 222 | D222D | gaC | gaT | 1 | 1 | R.1 | 0.00009 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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