CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp14A2-B : CodonNum = 129 & Codon = Gat

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp14A2-B129N129DN6054DnonsynAatGat1269931267190.99784218424-18426

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp14A2-B129N129DAatGat126719126993All0.024237
ORF1ab/nsp14A2-B129N129DAatGat111823112093B.1.20.984643
ORF1ab/nsp14A2-B129N129DAatGat1096410966B.1.5960.955385
ORF1ab/nsp14A2-B129N129DAatGat27732775B.10.025399
ORF1ab/nsp14A2-B129N129DAatGat222222B.1.10.004027
ORF1ab/nsp14A2-B129N129DAatGat116116B.1.5950.030271
ORF1ab/nsp14A2-B129N129DAatGat115115B.1.5800.46748
ORF1ab/nsp14A2-B129N129DAatGat5757B.1.2340.007521
ORF1ab/nsp14A2-B129N129DAatGat4545B.1.617.20.000169
ORF1ab/nsp14A2-B129N129DAatGat4444B.1.1.70.000039
ORF1ab/nsp14A2-B129N129DAatGat3737B.1.177.730.020951
ORF1ab/nsp14A2-B129N129DAatGat2424AY.250.000144
ORF1ab/nsp14A2-B129N129DAatGat2424B.1.3960.016937
ORF1ab/nsp14A2-B129N129DAatGat2222B.1.1.3350.285714
ORF1ab/nsp14A2-B129N129DAatGat1919B.1.2430.001322
ORF1ab/nsp14A2-B129N129DAatGat1818B.1.2060.014682
ORF1ab/nsp14A2-B129N129DAatGat1818B.1.5820.008832
ORF1ab/nsp14A2-B129N129DAatGat1717B.1.4290.0004
ORF1ab/nsp14A2-B129N129DAatGat1717B.1.5640.00724
ORF1ab/nsp14A2-B129N129DAatGat1515B.1.3690.004278
ORF1ab/nsp14A2-B129N129DAatGat1313B.1.5760.011786
ORF1ab/nsp14A2-B129N129DAatGat1212AY.440.000073
ORF1ab/nsp14A2-B129N129DAatGat1212B.1.5770.008247
ORF1ab/nsp14A2-B129N129DAatGat1111AY.40.000017
ORF1ab/nsp14A2-B129N129DAatGat1010AY.430.000044
ORF1ab/nsp14A2-B129N129DAatGat1010B.1.1.5190.000397
ORF1ab/nsp14A2-B129N129DAatGat99B.1.5260.000212
ORF1ab/nsp14A2-B129N129DAatGat88B.1.3110.002197
ORF1ab/nsp14A2-B129N129DAatGat77B.1.4270.000353
ORF1ab/nsp14A2-B129N129DAatGat66B.1.2840.078947
ORF1ab/nsp14A2-B129N129DAatGat66B.1.3750.004918
ORF1ab/nsp14A2-B129N129DAatGat66B.1.5170.002562
ORF1ab/nsp14A2-B129N129DAatGat66B.1.6090.002876
ORF1ab/nsp14A2-B129N129DAatGat66B.1.6120.015915
ORF1ab/nsp14A2-B129N129DAatGat55AY.1030.000031
ORF1ab/nsp14A2-B129N129DAatGat55B.1.5650.004052
ORF1ab/nsp14A2-B129N129DAatGat55B.1.5670.016667
ORF1ab/nsp14A2-B129N129DAatGat55B.1.5900.022727
ORF1ab/nsp14A2-B129N129DAatGat44AY.230.000279
ORF1ab/nsp14A2-B129N129DAatGat44AY.260.000113
ORF1ab/nsp14A2-B129N129DAatGat44AY.950.003044
ORF1ab/nsp14A2-B129N129DAatGat44B.1.1770.000053
ORF1ab/nsp14A2-B129N129DAatGat44B.1.3490.002859
ORF1ab/nsp14A2-B129N129DAatGat44B.1.5250.000453
ORF1ab/nsp14A2-B129N129DAatGat44B.1.5890.030303
ORF1ab/nsp14A2-B129N129DAatGat44B.1.780.034188
ORF1ab/nsp14A2-B129N129DAatGat33AY.30.00003
ORF1ab/nsp14A2-B129N129DAatGat33B.1.1.3370.010791
ORF1ab/nsp14A2-B129N129DAatGat33B.1.177.70.000495
ORF1ab/nsp14A2-B129N129DAatGat33B.1.1890.012876
ORF1ab/nsp14A2-B129N129DAatGat33B.1.2100.006397
ORF1ab/nsp14A2-B129N129DAatGat33B.1.3240.004815
ORF1ab/nsp14A2-B129N129DAatGat22AY.520.001629
ORF1ab/nsp14A2-B129N129DAatGat22AY.75.10.000361
ORF1ab/nsp14A2-B129N129DAatGat22AY.920.000575
ORF1ab/nsp14A2-B129N129DAatGat22B0.000256
ORF1ab/nsp14A2-B129N129DAatGat22B.1.1.2100.011429
ORF1ab/nsp14A2-B129N129DAatGat22B.1.1.2220.000408
ORF1ab/nsp14A2-B129N129DAatGat22B.1.1.2580.006515
ORF1ab/nsp14A2-B129N129DAatGat22B.1.1.5070.017391
ORF1ab/nsp14A2-B129N129DAatGat22B.1.110.30.001437
ORF1ab/nsp14A2-B129N129DAatGat22B.1.1110.00235
ORF1ab/nsp14A2-B129N129DAatGat22B.1.2210.000142
ORF1ab/nsp14A2-B129N129DAatGat22B.1.2390.002442
ORF1ab/nsp14A2-B129N129DAatGat22B.1.2400.000431
ORF1ab/nsp14A2-B129N129DAatGat22B.1.3050.004301
ORF1ab/nsp14A2-B129N129DAatGat22B.1.3300.057143
ORF1ab/nsp14A2-B129N129DAatGat22B.1.3360.004878
ORF1ab/nsp14A2-B129N129DAatGat22B.1.3400.008584
ORF1ab/nsp14A2-B129N129DAatGat22B.1.3610.002577
ORF1ab/nsp14A2-B129N129DAatGat22B.1.3670.001585
ORF1ab/nsp14A2-B129N129DAatGat22B.1.3780.013699
ORF1ab/nsp14A2-B129N129DAatGat22B.1.4000.000858
ORF1ab/nsp14A2-B129N129DAatGat22B.1.4170.057143
ORF1ab/nsp14A2-B129N129DAatGat22B.1.4360.002058
ORF1ab/nsp14A2-B129N129DAatGat22B.1.5740.004301
ORF1ab/nsp14A2-B129N129DAatGat22B.1.5880.00182
ORF1ab/nsp14A2-B129N129DAatGat22B.1.5990.007299
ORF1ab/nsp14A2-B129N129DAatGat22B.1.6060.012048
ORF1ab/nsp14A2-B129N129DAatGat22B.1.6230.001073
ORF1ab/nsp14A2-B129N129DAatGat22B.1.88.10.009615
ORF1ab/nsp14A2-B129N129DAatGat22C.36.20.068966
ORF1ab/nsp14A2-B129N129DAatGat22P.10.000032
ORF1ab/nsp14A2-B129N129DAatGat22P.1.10.000635
ORF1ab/nsp14A2-B129N129DAatGat22P.1.10.10.01626
ORF1ab/nsp14A2-B129N129DAatGat22P.20.000373
ORF1ab/nsp14A2-B129N129DAatGat110.055556
ORF1ab/nsp14A2-B129N129DAatGat11AY.1000.000046
ORF1ab/nsp14A2-B129N129DAatGat11AY.1130.000142
ORF1ab/nsp14A2-B129N129DAatGat11AY.1180.000063
ORF1ab/nsp14A2-B129N129DAatGat11AY.1190.000035
ORF1ab/nsp14A2-B129N129DAatGat11AY.140.000088
ORF1ab/nsp14A2-B129N129DAatGat11AY.16.10.00047
ORF1ab/nsp14A2-B129N129DAatGat11AY.390.000025
ORF1ab/nsp14A2-B129N129DAatGat11AY.4.20.000022
ORF1ab/nsp14A2-B129N129DAatGat11AY.420.00004
ORF1ab/nsp14A2-B129N129DAatGat11AY.450.000122
ORF1ab/nsp14A2-B129N129DAatGat11AY.470.000031
ORF1ab/nsp14A2-B129N129DAatGat11AY.50.000021
ORF1ab/nsp14A2-B129N129DAatGat11AY.840.000437
ORF1ab/nsp14A2-B129N129DAatGat11AY.9.20.000037
ORF1ab/nsp14A2-B129N129DAatGat11AY.960.002075
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.10.000327
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.1610.003534
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.1770.019231
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.2200.001859
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.2250.007194
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.2260.005814
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.2310.003096
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.250.000569
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.2510.007937
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.280.000311
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.3500.04
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.3890.006061
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.4020.011111
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.4090.002833
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.4210.030303
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.4320.001266
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.4340.000349
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.440.00241
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.4660.008696
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.4860.001577
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.50.008333
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.5260.003546
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1.830.00271
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1260.001276
ORF1ab/nsp14A2-B129N129DAatGat11B.1.1390.000733
ORF1ab/nsp14A2-B129N129DAatGat11B.1.2140.003663
ORF1ab/nsp14A2-B129N129DAatGat11B.1.2320.000537
ORF1ab/nsp14A2-B129N129DAatGat11B.1.2360.002053
ORF1ab/nsp14A2-B129N129DAatGat11B.1.2650.001271
ORF1ab/nsp14A2-B129N129DAatGat11B.1.3060.005714
ORF1ab/nsp14A2-B129N129DAatGat11B.1.3250.006897
ORF1ab/nsp14A2-B129N129DAatGat11B.1.3460.001311
ORF1ab/nsp14A2-B129N129DAatGat11B.1.3500.002933
ORF1ab/nsp14A2-B129N129DAatGat11B.1.3510.00003
ORF1ab/nsp14A2-B129N129DAatGat11B.1.3550.011111
ORF1ab/nsp14A2-B129N129DAatGat11B.1.3560.001727
ORF1ab/nsp14A2-B129N129DAatGat11B.1.360.000146
ORF1ab/nsp14A2-B129N129DAatGat11B.1.3630.012987
ORF1ab/nsp14A2-B129N129DAatGat11B.1.3950.007042
ORF1ab/nsp14A2-B129N129DAatGat11B.1.400.10.015152
ORF1ab/nsp14A2-B129N129DAatGat11B.1.4040.001302
ORF1ab/nsp14A2-B129N129DAatGat11B.1.4080.00369
ORF1ab/nsp14A2-B129N129DAatGat11B.1.4090.000781
ORF1ab/nsp14A2-B129N129DAatGat11B.1.4130.004255
ORF1ab/nsp14A2-B129N129DAatGat11B.1.4160.001269
ORF1ab/nsp14A2-B129N129DAatGat11B.1.4230.010204
ORF1ab/nsp14A2-B129N129DAatGat11B.1.4280.00102
ORF1ab/nsp14A2-B129N129DAatGat11B.1.4330.003195
ORF1ab/nsp14A2-B129N129DAatGat11B.1.4430.004673
ORF1ab/nsp14A2-B129N129DAatGat11B.1.4480.002625
ORF1ab/nsp14A2-B129N129DAatGat11B.1.4500.011364
ORF1ab/nsp14A2-B129N129DAatGat11B.1.4730.019231
ORF1ab/nsp14A2-B129N129DAatGat11B.1.5010.007353
ORF1ab/nsp14A2-B129N129DAatGat11B.1.5030.002488
ORF1ab/nsp14A2-B129N129DAatGat11B.1.5110.034483
ORF1ab/nsp14A2-B129N129DAatGat11B.1.5210.004975
ORF1ab/nsp14A2-B129N129DAatGat11B.1.5410.004425
ORF1ab/nsp14A2-B129N129DAatGat11B.1.5500.013699
ORF1ab/nsp14A2-B129N129DAatGat11B.1.5560.007519
ORF1ab/nsp14A2-B129N129DAatGat11B.1.5580.004566
ORF1ab/nsp14A2-B129N129DAatGat11B.1.5610.000397
ORF1ab/nsp14A2-B129N129DAatGat11B.1.5660.019231
ORF1ab/nsp14A2-B129N129DAatGat11B.1.5690.014493
ORF1ab/nsp14A2-B129N129DAatGat11B.1.5710.009709
ORF1ab/nsp14A2-B129N129DAatGat11B.1.5810.009434
ORF1ab/nsp14A2-B129N129DAatGat11B.1.5930.01087
ORF1ab/nsp14A2-B129N129DAatGat11B.1.595.20.04
ORF1ab/nsp14A2-B129N129DAatGat11B.1.6050.005952
ORF1ab/nsp14A2-B129N129DAatGat11B.1.6110.04
ORF1ab/nsp14A2-B129N129DAatGat11C.230.005814
ORF1ab/nsp14A2-B129N129DAatGat11P.1.100.000269
ORF1ab/nsp14A2-B129N129DAatGat11Q.10.000126
ORF1ab/nsp14A2-B129N129DAatGat11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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