CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp14A2-B : CodonNum = 115 & Codon = gtC

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp14A2-B115V115VV6040VsyngtTgtC7456950.93288618382-18384

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp14A2-B115V115VgtTgtC695745All0.000133
ORF1ab/nsp14A2-B115V115VgtTgtC494494AY.1010.242276
ORF1ab/nsp14A2-B115V115VgtTgtC4648B.1.1.70.000041
ORF1ab/nsp14A2-B115V115VgtTgtC1639B.1.617.20.00006
ORF1ab/nsp14A2-B115V115VgtTgtC2626B.1.4290.000612
ORF1ab/nsp14A2-B115V115VgtTgtC2021AY.40.000031
ORF1ab/nsp14A2-B115V115VgtTgtC615AY.430.000027
ORF1ab/nsp14A2-B115V115VgtTgtC88P.10.000126
ORF1ab/nsp14A2-B115V115VgtTgtC67AY.440.000037
ORF1ab/nsp14A2-B115V115VgtTgtC66AY.1020.000159
ORF1ab/nsp14A2-B115V115VgtTgtC55AY.1170.000423
ORF1ab/nsp14A2-B115V115VgtTgtC55AY.230.000349
ORF1ab/nsp14A2-B115V115VgtTgtC44AY.1030.000025
ORF1ab/nsp14A2-B115V115VgtTgtC44AY.460.000416
ORF1ab/nsp14A2-B115V115VgtTgtC44Q.40.001819
ORF1ab/nsp14A2-B115V115VgtTgtC23B.10.000018
ORF1ab/nsp14A2-B115V115VgtTgtC23B.1.20.000018
ORF1ab/nsp14A2-B115V115VgtTgtC33B.1.6210.000266
ORF1ab/nsp14A2-B115V115VgtTgtC33B.1.6310.010101
ORF1ab/nsp14A2-B115V115VgtTgtC22AY.1060.00067
ORF1ab/nsp14A2-B115V115VgtTgtC22AY.1190.000071
ORF1ab/nsp14A2-B115V115VgtTgtC12AY.1200.000037
ORF1ab/nsp14A2-B115V115VgtTgtC22AY.320.001065
ORF1ab/nsp14A2-B115V115VgtTgtC22AY.340.000194
ORF1ab/nsp14A2-B115V115VgtTgtC22AY.60.000082
ORF1ab/nsp14A2-B115V115VgtTgtC12B.1.10.000018
ORF1ab/nsp14A2-B115V115VgtTgtC22B.1.3110.000549
ORF1ab/nsp14A2-B115V115VgtTgtC11AY.16.10.00047
ORF1ab/nsp14A2-B115V115VgtTgtC11AY.20.000356
ORF1ab/nsp14A2-B115V115VgtTgtC11AY.250.000006
ORF1ab/nsp14A2-B115V115VgtTgtC11AY.260.000028
ORF1ab/nsp14A2-B115V115VgtTgtC11AY.360.000148
ORF1ab/nsp14A2-B115V115VgtTgtC11AY.390.000025
ORF1ab/nsp14A2-B115V115VgtTgtC11AY.420.00004
ORF1ab/nsp14A2-B115V115VgtTgtC11AY.450.000122
ORF1ab/nsp14A2-B115V115VgtTgtC11AY.480.000465
ORF1ab/nsp14A2-B115V115VgtTgtC11AY.590.00053
ORF1ab/nsp14A2-B115V115VgtTgtC11AY.840.000437
ORF1ab/nsp14A2-B115V115VgtTgtC11B.1.1770.000013
ORF1ab/nsp14A2-B115V115VgtTgtC11B.1.177.790.002342
ORF1ab/nsp14A2-B115V115VgtTgtC11B.1.177.800.001912
ORF1ab/nsp14A2-B115V115VgtTgtC11B.1.2580.000067
ORF1ab/nsp14A2-B115V115VgtTgtC11B.1.258.170.000104
ORF1ab/nsp14A2-B115V115VgtTgtC11B.1.3200.001245
ORF1ab/nsp14A2-B115V115VgtTgtC11B.1.5260.000024
ORF1ab/nsp14A2-B115V115VgtTgtC11B.1.6200.000946
ORF1ab/nsp14A2-B115V115VgtTgtC11B.450.003831
ORF1ab/nsp14A2-B115V115VgtTgtC11P.1.140.000048

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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