CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : Mut = Y277N

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13277Y277NY5601NnonsynTatAat68630.92647117065-17067
ORF1ab/nsp13277Y277NY5601NnonsynTaTAaC6850.073529417065-17067

Details of the mutation Y277N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13277Y277NTatAat6368All0.000012
ORF1ab/nsp13277Y277NTaTAaC568All0.000001
ORF1ab/nsp13277Y277NTatAat2121B.1.10.000381
ORF1ab/nsp13277Y277NTatAat510B.1.1.280.001556
ORF1ab/nsp13277Y277NTaTAaC510B.1.1.280.001556
ORF1ab/nsp13277Y277NTatAat66B.1.1.2940.007595
ORF1ab/nsp13277Y277NTatAat33AY.430.000013
ORF1ab/nsp13277Y277NTatAat33B.1.1.70.000003
ORF1ab/nsp13277Y277NTatAat33B.1.1770.00004
ORF1ab/nsp13277Y277NTatAat22B.1.1.3170.000823
ORF1ab/nsp13277Y277NTatAat22B.1.4290.000047
ORF1ab/nsp13277Y277NTatAat22D.20.00015
ORF1ab/nsp13277Y277NTatAat110.055556
ORF1ab/nsp13277Y277NTatAat11AY.1020.000027
ORF1ab/nsp13277Y277NTatAat11AY.460.000104
ORF1ab/nsp13277Y277NTatAat11AY.50.000021
ORF1ab/nsp13277Y277NTatAat11AY.980.000079
ORF1ab/nsp13277Y277NTatAat11B.1.1.2410.00207
ORF1ab/nsp13277Y277NTatAat11B.1.1.330.000421
ORF1ab/nsp13277Y277NTatAat11B.1.1.3490.010309
ORF1ab/nsp13277Y277NTatAat11B.1.1.390.00051
ORF1ab/nsp13277Y277NTatAat11B.1.1.4240.045455
ORF1ab/nsp13277Y277NTatAat11B.1.1.5140.038462
ORF1ab/nsp13277Y277NTatAat11B.1.1600.000031
ORF1ab/nsp13277Y277NTatAat11B.1.177.210.000076
ORF1ab/nsp13277Y277NTatAat11B.1.177.780.009709
ORF1ab/nsp13277Y277NTatAat11B.1.2360.002053
ORF1ab/nsp13277Y277NTatAat11B.1.4520.013699

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.