CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : Mut = V484V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13484V484VV5808VsyngtTgtC8478180.96576117686-17688
ORF1ab/nsp13484V484VV5808VsyngtTgtG847210.024793417686-17688
ORF1ab/nsp13484V484VV5808VsyngtTgtA84780.009445117686-17688

Details of the mutation V484V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13484V484VgtTgtC818847All0.000156
ORF1ab/nsp13484V484VgtTgtG21847All0.000004
ORF1ab/nsp13484V484VgtTgtA8847All0.000002
ORF1ab/nsp13484V484VgtTgtC250261B.1.1.70.000224
ORF1ab/nsp13484V484VgtTgtG10261B.1.1.70.000009
ORF1ab/nsp13484V484VgtTgtA1261B.1.1.70.000001
ORF1ab/nsp13484V484VgtTgtC184184B.1.2180.948454
ORF1ab/nsp13484V484VgtTgtC8889AY.40.000137
ORF1ab/nsp13484V484VgtTgtG189AY.40.000002
ORF1ab/nsp13484V484VgtTgtC8989B.1.617.20.000335
ORF1ab/nsp13484V484VgtTgtC3535AY.430.000155
ORF1ab/nsp13484V484VgtTgtC2929B.1.20.000255
ORF1ab/nsp13484V484VgtTgtC1414AY.440.000085
ORF1ab/nsp13484V484VgtTgtC1111B.1.1770.000145
ORF1ab/nsp13484V484VgtTgtC910B.1.10.000163
ORF1ab/nsp13484V484VgtTgtG110B.1.10.000018
ORF1ab/nsp13484V484VgtTgtC510P.10.000079
ORF1ab/nsp13484V484VgtTgtA310P.10.000047
ORF1ab/nsp13484V484VgtTgtG210P.10.000032
ORF1ab/nsp13484V484VgtTgtC88AY.4.20.000174
ORF1ab/nsp13484V484VgtTgtC67B.1.3510.000178
ORF1ab/nsp13484V484VgtTgtA17B.1.3510.00003
ORF1ab/nsp13484V484VgtTgtC56AY.1030.000031
ORF1ab/nsp13484V484VgtTgtG16AY.1030.000006
ORF1ab/nsp13484V484VgtTgtC66AY.390.000148
ORF1ab/nsp13484V484VgtTgtC55AY.9.20.000184
ORF1ab/nsp13484V484VgtTgtC55B.1.4710.013661
ORF1ab/nsp13484V484VgtTgtG34AY.30.00003
ORF1ab/nsp13484V484VgtTgtC14AY.30.00001
ORF1ab/nsp13484V484VgtTgtC44B.1.3110.001098
ORF1ab/nsp13484V484VgtTgtC44B.1.6090.001918
ORF1ab/nsp13484V484VgtTgtC33AY.1020.00008
ORF1ab/nsp13484V484VgtTgtC33AY.160.001139
ORF1ab/nsp13484V484VgtTgtC33AY.250.000018
ORF1ab/nsp13484V484VgtTgtC33B.10.000027
ORF1ab/nsp13484V484VgtTgtC33B.1.360.000438
ORF1ab/nsp13484V484VgtTgtC33B.1.5260.000071
ORF1ab/nsp13484V484VgtTgtC22AD.20.000438
ORF1ab/nsp13484V484VgtTgtC22AY.200.000078
ORF1ab/nsp13484V484VgtTgtC22AY.240.000862
ORF1ab/nsp13484V484VgtTgtC22AY.360.000296
ORF1ab/nsp13484V484VgtTgtC22B.1.1.3590.055556
ORF1ab/nsp13484V484VgtTgtC22B.1.1600.000062
ORF1ab/nsp13484V484VgtTgtA12B.1.2210.000071
ORF1ab/nsp13484V484VgtTgtC12B.1.2210.000071
ORF1ab/nsp13484V484VgtTgtC12B.1.2580.000067
ORF1ab/nsp13484V484VgtTgtG12B.1.2580.000067
ORF1ab/nsp13484V484VgtTgtC22B.1.36.170.000988
ORF1ab/nsp13484V484VgtTgtC11A0.000387
ORF1ab/nsp13484V484VgtTgtC11AY.1110.000183
ORF1ab/nsp13484V484VgtTgtC11AY.116.10.000311
ORF1ab/nsp13484V484VgtTgtC11AY.1200.000037
ORF1ab/nsp13484V484VgtTgtA11AY.140.000088
ORF1ab/nsp13484V484VgtTgtC11AY.260.000028
ORF1ab/nsp13484V484VgtTgtG11AY.290.000016
ORF1ab/nsp13484V484VgtTgtC11AY.350.000233
ORF1ab/nsp13484V484VgtTgtC11AY.39.10.00004
ORF1ab/nsp13484V484VgtTgtC11AY.5.40.000277
ORF1ab/nsp13484V484VgtTgtC11AY.550.000917
ORF1ab/nsp13484V484VgtTgtC11AY.610.000105
ORF1ab/nsp13484V484VgtTgtC11AY.690.000187
ORF1ab/nsp13484V484VgtTgtC11AY.750.000056
ORF1ab/nsp13484V484VgtTgtC11B.1.1.1590.004673
ORF1ab/nsp13484V484VgtTgtC11B.1.1.1650.015385
ORF1ab/nsp13484V484VgtTgtC11B.1.1.2840.000107
ORF1ab/nsp13484V484VgtTgtC11B.1.177.620.001192
ORF1ab/nsp13484V484VgtTgtC11B.1.3500.002933
ORF1ab/nsp13484V484VgtTgtC11B.1.4030.003268
ORF1ab/nsp13484V484VgtTgtA11B.1.4270.00005
ORF1ab/nsp13484V484VgtTgtC11B.1.5250.000113
ORF1ab/nsp13484V484VgtTgtG11B.1.5890.007576
ORF1ab/nsp13484V484VgtTgtC11B.1.6200.000946
ORF1ab/nsp13484V484VgtTgtC11B.1.6210.000089
ORF1ab/nsp13484V484VgtTgtC11C.170.055556
ORF1ab/nsp13484V484VgtTgtC11P.1.100.000269
ORF1ab/nsp13484V484VgtTgtC11P.1.150.000232
ORF1ab/nsp13484V484VgtTgtC11P.1.160.000374
ORF1ab/nsp13484V484VgtTgtC11P.60.003145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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