CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : Mut = V484F

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13484V484FV5808FnonsynGttTtt997997117686-17688

Details of the mutation V484F within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13484V484FGttTtt997997All0.000191
ORF1ab/nsp13484V484FGttTtt206206B.1.1.70.000184
ORF1ab/nsp13484V484FGttTtt132132AY.40.000205
ORF1ab/nsp13484V484FGttTtt9696AY.1200.003569
ORF1ab/nsp13484V484FGttTtt7272AY.430.000319
ORF1ab/nsp13484V484FGttTtt7070B.1.20.000616
ORF1ab/nsp13484V484FGttTtt4545B.1.258.110.017836
ORF1ab/nsp13484V484FGttTtt3939B.1.1600.001216
ORF1ab/nsp13484V484FGttTtt2828B.1.617.10.003611
ORF1ab/nsp13484V484FGttTtt2222B.1.438.10.00236
ORF1ab/nsp13484V484FGttTtt2222B.1.617.20.000083
ORF1ab/nsp13484V484FGttTtt1414AY.1030.000087
ORF1ab/nsp13484V484FGttTtt1414B.1.2210.000994
ORF1ab/nsp13484V484FGttTtt1313AY.50.000268
ORF1ab/nsp13484V484FGttTtt1212B.1.10.000218
ORF1ab/nsp13484V484FGttTtt1010B.1.2580.000665
ORF1ab/nsp13484V484FGttTtt88AY.440.000049
ORF1ab/nsp13484V484FGttTtt88B.10.000073
ORF1ab/nsp13484V484FGttTtt77AY.250.000042
ORF1ab/nsp13484V484FGttTtt77AY.30.00007
ORF1ab/nsp13484V484FGttTtt77B.1.1.5260.024823
ORF1ab/nsp13484V484FGttTtt77B.1.4290.000165
ORF1ab/nsp13484V484FGttTtt66AY.1020.000159
ORF1ab/nsp13484V484FGttTtt66B.1.1.3050.023166
ORF1ab/nsp13484V484FGttTtt66B.1.1770.000079
ORF1ab/nsp13484V484FGttTtt66B.1.3750.004918
ORF1ab/nsp13484V484FGttTtt44AY.290.000063
ORF1ab/nsp13484V484FGttTtt44AY.470.000124
ORF1ab/nsp13484V484FGttTtt44AY.60.000165
ORF1ab/nsp13484V484FGttTtt44B.1.6210.000354
ORF1ab/nsp13484V484FGttTtt33AY.200.000117
ORF1ab/nsp13484V484FGttTtt33AY.260.000085
ORF1ab/nsp13484V484FGttTtt33AY.39.1.10.002174
ORF1ab/nsp13484V484FGttTtt33AY.970.005102
ORF1ab/nsp13484V484FGttTtt33AY.99.20.000276
ORF1ab/nsp13484V484FGttTtt33B.1.1.1870.026549
ORF1ab/nsp13484V484FGttTtt33B.1.160.140.006356
ORF1ab/nsp13484V484FGttTtt33B.1.177.90.003995
ORF1ab/nsp13484V484FGttTtt33B.1.5460.011111
ORF1ab/nsp13484V484FGttTtt33D.20.000225
ORF1ab/nsp13484V484FGttTtt33P.10.000047
ORF1ab/nsp13484V484FGttTtt33P.1.170.000485
ORF1ab/nsp13484V484FGttTtt22AY.1130.000285
ORF1ab/nsp13484V484FGttTtt22AY.20.000712
ORF1ab/nsp13484V484FGttTtt22AY.230.000139
ORF1ab/nsp13484V484FGttTtt22AY.340.000194
ORF1ab/nsp13484V484FGttTtt22AY.510.001818
ORF1ab/nsp13484V484FGttTtt22AY.90.000135
ORF1ab/nsp13484V484FGttTtt22B0.000256
ORF1ab/nsp13484V484FGttTtt22B.1.1.2140.000111
ORF1ab/nsp13484V484FGttTtt22B.1.1.370.000386
ORF1ab/nsp13484V484FGttTtt22B.1.1.4170.005405
ORF1ab/nsp13484V484FGttTtt22B.1.1.5190.000079
ORF1ab/nsp13484V484FGttTtt22B.1.160.270.030303
ORF1ab/nsp13484V484FGttTtt22B.1.2370.00995
ORF1ab/nsp13484V484FGttTtt22B.1.360.000292
ORF1ab/nsp13484V484FGttTtt22B.4.50.02381
ORF1ab/nsp13484V484FGttTtt22Q.30.00029
ORF1ab/nsp13484V484FGttTtt22Q.70.002222
ORF1ab/nsp13484V484FGttTtt110.055556
ORF1ab/nsp13484V484FGttTtt11A.10.000282
ORF1ab/nsp13484V484FGttTtt11AP.10.001502
ORF1ab/nsp13484V484FGttTtt11AY.1000.000046
ORF1ab/nsp13484V484FGttTtt11AY.1060.000335
ORF1ab/nsp13484V484FGttTtt11AY.1160.000287
ORF1ab/nsp13484V484FGttTtt11AY.116.10.000311
ORF1ab/nsp13484V484FGttTtt11AY.1210.000135
ORF1ab/nsp13484V484FGttTtt11AY.23.10.000417
ORF1ab/nsp13484V484FGttTtt11AY.39.10.00004
ORF1ab/nsp13484V484FGttTtt11AY.410.000294
ORF1ab/nsp13484V484FGttTtt11AY.420.00004
ORF1ab/nsp13484V484FGttTtt11AY.46.10.001027
ORF1ab/nsp13484V484FGttTtt11AY.46.40.000165
ORF1ab/nsp13484V484FGttTtt11AY.46.60.000072
ORF1ab/nsp13484V484FGttTtt11AY.500.000799
ORF1ab/nsp13484V484FGttTtt11AY.600.000938
ORF1ab/nsp13484V484FGttTtt11AY.690.000187
ORF1ab/nsp13484V484FGttTtt11AY.9.20.000037
ORF1ab/nsp13484V484FGttTtt11AY.98.10.000048
ORF1ab/nsp13484V484FGttTtt11AY.99.10.001553
ORF1ab/nsp13484V484FGttTtt11B.1.1.1700.001247
ORF1ab/nsp13484V484FGttTtt11B.1.1.2220.000204
ORF1ab/nsp13484V484FGttTtt11B.1.1.2630.001558
ORF1ab/nsp13484V484FGttTtt11B.1.1.3030.002762
ORF1ab/nsp13484V484FGttTtt11B.1.1.4860.001577
ORF1ab/nsp13484V484FGttTtt11B.1.1.670.004566
ORF1ab/nsp13484V484FGttTtt11B.1.177.450.000381
ORF1ab/nsp13484V484FGttTtt11B.1.177.860.000183
ORF1ab/nsp13484V484FGttTtt11B.1.2320.000537
ORF1ab/nsp13484V484FGttTtt11B.1.2430.00007
ORF1ab/nsp13484V484FGttTtt11B.1.258.50.008772
ORF1ab/nsp13484V484FGttTtt11B.1.3110.000275
ORF1ab/nsp13484V484FGttTtt11B.1.36.10.00114
ORF1ab/nsp13484V484FGttTtt11B.1.36.360.000602
ORF1ab/nsp13484V484FGttTtt11B.1.36.80.001
ORF1ab/nsp13484V484FGttTtt11B.1.4270.00005
ORF1ab/nsp13484V484FGttTtt11B.1.5950.000261
ORF1ab/nsp13484V484FGttTtt11B.1.6370.000073
ORF1ab/nsp13484V484FGttTtt11B.1.90.006173
ORF1ab/nsp13484V484FGttTtt11B.100.008264
ORF1ab/nsp13484V484FGttTtt11B.30.000831
ORF1ab/nsp13484V484FGttTtt11B.310.003731
ORF1ab/nsp13484V484FGttTtt11C.360.000911
ORF1ab/nsp13484V484FGttTtt11C.370.000116
ORF1ab/nsp13484V484FGttTtt11P.1.140.000048
ORF1ab/nsp13484V484FGttTtt11P.1.70.000319
ORF1ab/nsp13484V484FGttTtt11P.20.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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