CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : Mut = V305V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13305V305VV5629VsyngtGgtA6955420.77985617149-17151
ORF1ab/nsp13305V305VV5629VsyngtGgtT6951380.19856117149-17151
ORF1ab/nsp13305V305VV5629VsyngtGgtC695150.021582717149-17151

Details of the mutation V305V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13305V305VgtGgtA542695All0.000104
ORF1ab/nsp13305V305VgtGgtT138695All0.000026
ORF1ab/nsp13305V305VgtGgtC15695All0.000003
ORF1ab/nsp13305V305VgtGgtA149160B.1.1.70.000133
ORF1ab/nsp13305V305VgtGgtT11160B.1.1.70.00001
ORF1ab/nsp13305V305VgtGgtA116117B.1.10.002104
ORF1ab/nsp13305V305VgtGgtC1117B.1.10.000018
ORF1ab/nsp13305V305VgtGgtA102102AY.5.20.251232
ORF1ab/nsp13305V305VgtGgtT6363B.1.4320.707865
ORF1ab/nsp13305V305VgtGgtA2831AY.40.000044
ORF1ab/nsp13305V305VgtGgtT331AY.40.000005
ORF1ab/nsp13305V305VgtGgtT1122B.10.000101
ORF1ab/nsp13305V305VgtGgtC622B.10.000055
ORF1ab/nsp13305V305VgtGgtA522B.10.000046
ORF1ab/nsp13305V305VgtGgtT1220AY.440.000073
ORF1ab/nsp13305V305VgtGgtA820AY.440.000049
ORF1ab/nsp13305V305VgtGgtA1212AY.200.000466
ORF1ab/nsp13305V305VgtGgtT1212B.1.3490.008578
ORF1ab/nsp13305V305VgtGgtA712B.1.617.20.000026
ORF1ab/nsp13305V305VgtGgtT512B.1.617.20.000019
ORF1ab/nsp13305V305VgtGgtA99AY.250.000054
ORF1ab/nsp13305V305VgtGgtA99AY.98.10.000436
ORF1ab/nsp13305V305VgtGgtA88AY.7.10.000902
ORF1ab/nsp13305V305VgtGgtA66B.1.177.70.000989
ORF1ab/nsp13305V305VgtGgtA36B.1.20.000026
ORF1ab/nsp13305V305VgtGgtT36B.1.20.000026
ORF1ab/nsp13305V305VgtGgtA55AY.1030.000031
ORF1ab/nsp13305V305VgtGgtA45AY.430.000018
ORF1ab/nsp13305V305VgtGgtT15AY.430.000004
ORF1ab/nsp13305V305VgtGgtA55B.1.1.5190.000199
ORF1ab/nsp13305V305VgtGgtA55B.1.1.610.04386
ORF1ab/nsp13305V305VgtGgtA34AY.50.000062
ORF1ab/nsp13305V305VgtGgtT14AY.50.000021
ORF1ab/nsp13305V305VgtGgtA33AY.260.000085
ORF1ab/nsp13305V305VgtGgtA33AY.4.20.000065
ORF1ab/nsp13305V305VgtGgtA23AY.920.000575
ORF1ab/nsp13305V305VgtGgtC13AY.920.000287
ORF1ab/nsp13305V305VgtGgtA33AY.99.20.000276
ORF1ab/nsp13305V305VgtGgtA33B.1.1.3760.017857
ORF1ab/nsp13305V305VgtGgtA22AY.1010.000981
ORF1ab/nsp13305V305VgtGgtA22AY.390.000049
ORF1ab/nsp13305V305VgtGgtA22AY.4.40.000818
ORF1ab/nsp13305V305VgtGgtT22AY.9.20.000073
ORF1ab/nsp13305V305VgtGgtA22B.1.1.1610.007067
ORF1ab/nsp13305V305VgtGgtA22B.1.1.1740.006757
ORF1ab/nsp13305V305VgtGgtA22B.1.1.2160.001781
ORF1ab/nsp13305V305VgtGgtA22B.1.1.330.000842
ORF1ab/nsp13305V305VgtGgtT12B.1.1600.000031
ORF1ab/nsp13305V305VgtGgtA12B.1.1600.000031
ORF1ab/nsp13305V305VgtGgtA22B.1.160.120.012821
ORF1ab/nsp13305V305VgtGgtC22B.1.2350.005038
ORF1ab/nsp13305V305VgtGgtA22B.1.258.220.005333
ORF1ab/nsp13305V305VgtGgtC12B.1.3980.002976
ORF1ab/nsp13305V305VgtGgtA12B.1.3980.002976
ORF1ab/nsp13305V305VgtGgtA22B.1.4160.002538
ORF1ab/nsp13305V305VgtGgtC22B.1.5820.000981
ORF1ab/nsp13305V305VgtGgtA11AY.1020.000027
ORF1ab/nsp13305V305VgtGgtT11AY.1100.000113
ORF1ab/nsp13305V305VgtGgtA11AY.1180.000063
ORF1ab/nsp13305V305VgtGgtA11AY.120.000316
ORF1ab/nsp13305V305VgtGgtA11AY.1200.000037
ORF1ab/nsp13305V305VgtGgtA11AY.30.00001
ORF1ab/nsp13305V305VgtGgtA11AY.3.10.000085
ORF1ab/nsp13305V305VgtGgtA11AY.410.000294
ORF1ab/nsp13305V305VgtGgtA11AY.420.00004
ORF1ab/nsp13305V305VgtGgtA11AY.460.000104
ORF1ab/nsp13305V305VgtGgtT11AY.46.60.000072
ORF1ab/nsp13305V305VgtGgtT11AY.470.000031
ORF1ab/nsp13305V305VgtGgtA11AY.480.000465
ORF1ab/nsp13305V305VgtGgtC11AY.5.30.000337
ORF1ab/nsp13305V305VgtGgtA11AY.650.000533
ORF1ab/nsp13305V305VgtGgtT11AY.820.001357
ORF1ab/nsp13305V305VgtGgtA11AY.840.000437
ORF1ab/nsp13305V305VgtGgtA11B0.000128
ORF1ab/nsp13305V305VgtGgtA11B.1.1.3060.000438
ORF1ab/nsp13305V305VgtGgtA11B.1.1.3720.000689
ORF1ab/nsp13305V305VgtGgtA11B.1.1.5180.006329
ORF1ab/nsp13305V305VgtGgtC11B.1.1670.007812
ORF1ab/nsp13305V305VgtGgtT11B.1.2340.000132
ORF1ab/nsp13305V305VgtGgtA11B.1.2430.00007
ORF1ab/nsp13305V305VgtGgtT11B.1.3510.00003
ORF1ab/nsp13305V305VgtGgtA11B.1.360.000146
ORF1ab/nsp13305V305VgtGgtT11B.1.36.370.002778
ORF1ab/nsp13305V305VgtGgtT11B.1.3960.000706
ORF1ab/nsp13305V305VgtGgtT11B.1.4000.000429
ORF1ab/nsp13305V305VgtGgtT11B.1.4240.008065
ORF1ab/nsp13305V305VgtGgtA11B.1.4290.000024
ORF1ab/nsp13305V305VgtGgtT11B.1.5960.000087
ORF1ab/nsp13305V305VgtGgtT11B.1.6210.000089
ORF1ab/nsp13305V305VgtGgtA11B.1.6280.000352
ORF1ab/nsp13305V305VgtGgtA11C.140.004329
ORF1ab/nsp13305V305VgtGgtT11P.10.000016
ORF1ab/nsp13305V305VgtGgtA11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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