CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : Mut = S485L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13485S485LS5809LnonsyntCatTa16351635117689-17691

Details of the mutation S485L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13485S485LtCatTa16351635All0.000313
ORF1ab/nsp13485S485LtCatTa160160B.1.9.40.981595
ORF1ab/nsp13485S485LtCatTa159159B.1.9.50.903409
ORF1ab/nsp13485S485LtCatTa155155B.10.00142
ORF1ab/nsp13485S485LtCatTa152152B.1.90.938272
ORF1ab/nsp13485S485LtCatTa140140AY.40.000218
ORF1ab/nsp13485S485LtCatTa126126B.1.1470.095238
ORF1ab/nsp13485S485LtCatTa6565AY.1140.015022
ORF1ab/nsp13485S485LtCatTa5252B.1.1.70.000047
ORF1ab/nsp13485S485LtCatTa3737B.1.617.20.000139
ORF1ab/nsp13485S485LtCatTa3535B.1.20.000308
ORF1ab/nsp13485S485LtCatTa3131B.1.9.11
ORF1ab/nsp13485S485LtCatTa2929B.1.36.170.014328
ORF1ab/nsp13485S485LtCatTa2626AY.250.000156
ORF1ab/nsp13485S485LtCatTa2626B.1.9.31
ORF1ab/nsp13485S485LtCatTa2222AY.30.000219
ORF1ab/nsp13485S485LtCatTa2020AY.430.000089
ORF1ab/nsp13485S485LtCatTa1818AY.1030.000112
ORF1ab/nsp13485S485LtCatTa1818AY.4.20.00039
ORF1ab/nsp13485S485LtCatTa1515B.1.36.180.006303
ORF1ab/nsp13485S485LtCatTa1414B.1.2340.001847
ORF1ab/nsp13485S485LtCatTa1111AY.440.000067
ORF1ab/nsp13485S485LtCatTa1010AY.46.60.000722
ORF1ab/nsp13485S485LtCatTa1010B.1.10.000181
ORF1ab/nsp13485S485LtCatTa1010B.1.3510.000297
ORF1ab/nsp13485S485LtCatTa1010B.1.4290.000235
ORF1ab/nsp13485S485LtCatTa1010B.1.9.21
ORF1ab/nsp13485S485LtCatTa99AY.1200.000335
ORF1ab/nsp13485S485LtCatTa99B.1.1770.000119
ORF1ab/nsp13485S485LtCatTa88AY.200.000311
ORF1ab/nsp13485S485LtCatTa88B0.001022
ORF1ab/nsp13485S485LtCatTa88B.1.1.2690.010825
ORF1ab/nsp13485S485LtCatTa77AY.290.00011
ORF1ab/nsp13485S485LtCatTa77AY.420.000282
ORF1ab/nsp13485S485LtCatTa66AY.1190.000212
ORF1ab/nsp13485S485LtCatTa66AY.390.000148
ORF1ab/nsp13485S485LtCatTa66B.1.5750.00182
ORF1ab/nsp13485S485LtCatTa66C.10.014354
ORF1ab/nsp13485S485LtCatTa55AY.1110.000916
ORF1ab/nsp13485S485LtCatTa55AY.1160.001434
ORF1ab/nsp13485S485LtCatTa55AY.230.000349
ORF1ab/nsp13485S485LtCatTa55AY.470.000156
ORF1ab/nsp13485S485LtCatTa55AY.50.000103
ORF1ab/nsp13485S485LtCatTa55B.1.4220.004062
ORF1ab/nsp13485S485LtCatTa55B.1.6210.000443
ORF1ab/nsp13485S485LtCatTa55D.20.000375
ORF1ab/nsp13485S485LtCatTa44AY.1130.00057
ORF1ab/nsp13485S485LtCatTa44AY.34.10.00204
ORF1ab/nsp13485S485LtCatTa44B.1.177.440.002076
ORF1ab/nsp13485S485LtCatTa44B.1.4250.011976
ORF1ab/nsp13485S485LtCatTa44C.400.111111
ORF1ab/nsp13485S485LtCatTa33AY.1020.00008
ORF1ab/nsp13485S485LtCatTa33AY.330.0002
ORF1ab/nsp13485S485LtCatTa33AY.9.20.00011
ORF1ab/nsp13485S485LtCatTa33AY.980.000237
ORF1ab/nsp13485S485LtCatTa33B.1.177.210.000229
ORF1ab/nsp13485S485LtCatTa33B.1.3710.003367
ORF1ab/nsp13485S485LtCatTa33B.1.3820.026786
ORF1ab/nsp13485S485LtCatTa33B.1.6200.002838
ORF1ab/nsp13485S485LtCatTa220.111111
ORF1ab/nsp13485S485LtCatTa22AY.1100.000225
ORF1ab/nsp13485S485LtCatTa22AY.260.000057
ORF1ab/nsp13485S485LtCatTa22AY.29.10.000441
ORF1ab/nsp13485S485LtCatTa22AY.450.000243
ORF1ab/nsp13485S485LtCatTa22AY.60.000082
ORF1ab/nsp13485S485LtCatTa22AY.750.000112
ORF1ab/nsp13485S485LtCatTa22AY.790.002421
ORF1ab/nsp13485S485LtCatTa22AY.98.10.000097
ORF1ab/nsp13485S485LtCatTa22B.1.1.2080.02439
ORF1ab/nsp13485S485LtCatTa22B.1.1.3180.000604
ORF1ab/nsp13485S485LtCatTa22B.1.1.5190.000079
ORF1ab/nsp13485S485LtCatTa22B.1.177.460.001837
ORF1ab/nsp13485S485LtCatTa22B.1.177.600.000437
ORF1ab/nsp13485S485LtCatTa22B.1.177.810.000379
ORF1ab/nsp13485S485LtCatTa22B.1.258.170.000208
ORF1ab/nsp13485S485LtCatTa22B.1.2840.026316
ORF1ab/nsp13485S485LtCatTa22B.1.351.20.000605
ORF1ab/nsp13485S485LtCatTa22B.1.360.000292
ORF1ab/nsp13485S485LtCatTa22B.1.3690.00057
ORF1ab/nsp13485S485LtCatTa22B.1.438.10.000215
ORF1ab/nsp13485S485LtCatTa22B.1.5330.019231
ORF1ab/nsp13485S485LtCatTa22M.30.153846
ORF1ab/nsp13485S485LtCatTa22P.10.000032
ORF1ab/nsp13485S485LtCatTa22P.1.140.000096
ORF1ab/nsp13485S485LtCatTa22Q.40.00091
ORF1ab/nsp13485S485LtCatTa22R.10.00018
ORF1ab/nsp13485S485LtCatTa11AT.10.005128
ORF1ab/nsp13485S485LtCatTa11AU.30.00211
ORF1ab/nsp13485S485LtCatTa11AY.1060.000335
ORF1ab/nsp13485S485LtCatTa11AY.1170.000085
ORF1ab/nsp13485S485LtCatTa11AY.39.10.00004
ORF1ab/nsp13485S485LtCatTa11AY.4.2.10.000149
ORF1ab/nsp13485S485LtCatTa11AY.4.40.000409
ORF1ab/nsp13485S485LtCatTa11AY.460.000104
ORF1ab/nsp13485S485LtCatTa11AY.620.000436
ORF1ab/nsp13485S485LtCatTa11AY.70.000196
ORF1ab/nsp13485S485LtCatTa11AY.710.000475
ORF1ab/nsp13485S485LtCatTa11AY.740.000116
ORF1ab/nsp13485S485LtCatTa11AY.80.000606
ORF1ab/nsp13485S485LtCatTa11AY.850.000427
ORF1ab/nsp13485S485LtCatTa11AY.950.000761
ORF1ab/nsp13485S485LtCatTa11B.1.1.1760.000439
ORF1ab/nsp13485S485LtCatTa11B.1.1.1890.001513
ORF1ab/nsp13485S485LtCatTa11B.1.1.2070.001182
ORF1ab/nsp13485S485LtCatTa11B.1.1.2140.000055
ORF1ab/nsp13485S485LtCatTa11B.1.1.2200.001859
ORF1ab/nsp13485S485LtCatTa11B.1.1.2220.000204
ORF1ab/nsp13485S485LtCatTa11B.1.1.2530.002506
ORF1ab/nsp13485S485LtCatTa11B.1.1.2940.001266
ORF1ab/nsp13485S485LtCatTa11B.1.1.3170.000412
ORF1ab/nsp13485S485LtCatTa11B.1.1.3260.001761
ORF1ab/nsp13485S485LtCatTa11B.1.1.3720.000689
ORF1ab/nsp13485S485LtCatTa11B.1.1.4020.011111
ORF1ab/nsp13485S485LtCatTa11B.1.1.4280.009434
ORF1ab/nsp13485S485LtCatTa11B.1.1.5230.001563
ORF1ab/nsp13485S485LtCatTa11B.1.1280.000635
ORF1ab/nsp13485S485LtCatTa11B.1.1490.003425
ORF1ab/nsp13485S485LtCatTa11B.1.1600.000031
ORF1ab/nsp13485S485LtCatTa11B.1.1700.00431
ORF1ab/nsp13485S485LtCatTa11B.1.177.120.000152
ORF1ab/nsp13485S485LtCatTa11B.1.177.150.000631
ORF1ab/nsp13485S485LtCatTa11B.1.177.40.000211
ORF1ab/nsp13485S485LtCatTa11B.1.177.730.000566
ORF1ab/nsp13485S485LtCatTa11B.1.177.860.000183
ORF1ab/nsp13485S485LtCatTa11B.1.2060.000816
ORF1ab/nsp13485S485LtCatTa11B.1.2390.001221
ORF1ab/nsp13485S485LtCatTa11B.1.3240.001605
ORF1ab/nsp13485S485LtCatTa11B.1.3260.007576
ORF1ab/nsp13485S485LtCatTa11B.1.3330.010526
ORF1ab/nsp13485S485LtCatTa11B.1.351.30.000876
ORF1ab/nsp13485S485LtCatTa11B.1.36.310.001751
ORF1ab/nsp13485S485LtCatTa11B.1.4330.003195
ORF1ab/nsp13485S485LtCatTa11B.1.466.20.000391
ORF1ab/nsp13485S485LtCatTa11B.1.4710.002732
ORF1ab/nsp13485S485LtCatTa11B.1.4990.00105
ORF1ab/nsp13485S485LtCatTa11B.1.5880.00091
ORF1ab/nsp13485S485LtCatTa11B.1.5960.000087
ORF1ab/nsp13485S485LtCatTa11B.1.6270.00202
ORF1ab/nsp13485S485LtCatTa11B.1.6370.000073
ORF1ab/nsp13485S485LtCatTa11B.400.000364
ORF1ab/nsp13485S485LtCatTa11B.60.00091
ORF1ab/nsp13485S485LtCatTa11C.370.000116

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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