CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : Mut = S166S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13166S166SS5490SsyntcAtcG6555920.90381716732-16734
ORF1ab/nsp13166S166SS5490SsyntcAtcT655440.067175616732-16734
ORF1ab/nsp13166S166SS5490SsyntcAtcC655180.027480916732-16734
ORF1ab/nsp13166S166SS5490SsynTCAAGT65510.0015267216732-16734

Details of the mutation S166S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13166S166StcAtcG592655All0.000113
ORF1ab/nsp13166S166StcAtcT44655All0.000008
ORF1ab/nsp13166S166StcAtcC18655All0.000003
ORF1ab/nsp13166S166STCAAGT1655All0
ORF1ab/nsp13166S166StcAtcG260260AY.360.038536
ORF1ab/nsp13166S166StcAtcG7480B.1.1.70.000066
ORF1ab/nsp13166S166StcAtcT480B.1.1.70.000004
ORF1ab/nsp13166S166StcAtcC280B.1.1.70.000002
ORF1ab/nsp13166S166StcAtcG5151B.1.2420.962264
ORF1ab/nsp13166S166StcAtcT2447AY.40.000037
ORF1ab/nsp13166S166StcAtcG1947AY.40.00003
ORF1ab/nsp13166S166StcAtcC447AY.40.000006
ORF1ab/nsp13166S166StcAtcG2929AY.450.003529
ORF1ab/nsp13166S166StcAtcG1919AY.1030.000118
ORF1ab/nsp13166S166StcAtcG1818B.1.1770.000237
ORF1ab/nsp13166S166StcAtcG1616AY.440.000097
ORF1ab/nsp13166S166StcAtcG1216B.1.617.20.000045
ORF1ab/nsp13166S166StcAtcC316B.1.617.20.000011
ORF1ab/nsp13166S166StcAtcT116B.1.617.20.000004
ORF1ab/nsp13166S166StcAtcG1414AY.420.000563
ORF1ab/nsp13166S166StcAtcG88AY.250.000048
ORF1ab/nsp13166S166StcAtcT25AY.430.000009
ORF1ab/nsp13166S166StcAtcG25AY.430.000009
ORF1ab/nsp13166S166StcAtcC15AY.430.000004
ORF1ab/nsp13166S166StcAtcG25B.1.10.000036
ORF1ab/nsp13166S166STCAAGT15B.1.10.000018
ORF1ab/nsp13166S166StcAtcC15B.1.10.000018
ORF1ab/nsp13166S166StcAtcT15B.1.10.000018
ORF1ab/nsp13166S166StcAtcG55B.1.258.170.00052
ORF1ab/nsp13166S166StcAtcG44B.1.360.000584
ORF1ab/nsp13166S166StcAtcG34P.10.000047
ORF1ab/nsp13166S166StcAtcC14P.10.000016
ORF1ab/nsp13166S166StcAtcT44P.1.140.000191
ORF1ab/nsp13166S166StcAtcG33AY.1020.00008
ORF1ab/nsp13166S166StcAtcG33B.1.258.30.005025
ORF1ab/nsp13166S166StcAtcG33B.1.36.290.001552
ORF1ab/nsp13166S166StcAtcG33B.1.5680.003333
ORF1ab/nsp13166S166StcAtcG22AY.1060.00067
ORF1ab/nsp13166S166StcAtcG12AY.1190.000035
ORF1ab/nsp13166S166StcAtcC12AY.1190.000035
ORF1ab/nsp13166S166StcAtcG22AY.39.10.000079
ORF1ab/nsp13166S166StcAtcG22AY.470.000062
ORF1ab/nsp13166S166StcAtcT12B.1.20.000009
ORF1ab/nsp13166S166StcAtcG12B.1.20.000009
ORF1ab/nsp13166S166StcAtcT12B.1.5260.000024
ORF1ab/nsp13166S166StcAtcG12B.1.5260.000024
ORF1ab/nsp13166S166StcAtcG22B.1.5650.001621
ORF1ab/nsp13166S166StcAtcG22B.1.6280.000705
ORF1ab/nsp13166S166StcAtcG22B.1.6370.000146
ORF1ab/nsp13166S166StcAtcG22P.1.150.000465
ORF1ab/nsp13166S166StcAtcG11AY.1010.00049
ORF1ab/nsp13166S166StcAtcG11AY.1050.000643
ORF1ab/nsp13166S166StcAtcG11AY.1100.000113
ORF1ab/nsp13166S166StcAtcG11AY.1110.000183
ORF1ab/nsp13166S166StcAtcT11AY.120.20.001285
ORF1ab/nsp13166S166StcAtcC11AY.130.000161
ORF1ab/nsp13166S166StcAtcG11AY.160.00038
ORF1ab/nsp13166S166StcAtcG11AY.230.00007
ORF1ab/nsp13166S166StcAtcG11AY.30.00001
ORF1ab/nsp13166S166StcAtcG11AY.390.000025
ORF1ab/nsp13166S166StcAtcT11AY.4.20.000022
ORF1ab/nsp13166S166StcAtcG11AY.46.30.000934
ORF1ab/nsp13166S166StcAtcG11AY.46.60.000072
ORF1ab/nsp13166S166StcAtcT11AY.60.000041
ORF1ab/nsp13166S166StcAtcT11AY.610.000105
ORF1ab/nsp13166S166StcAtcG11AY.750.000056
ORF1ab/nsp13166S166StcAtcT11AY.9.10.000084
ORF1ab/nsp13166S166StcAtcG11AY.9.20.000037
ORF1ab/nsp13166S166StcAtcT11B.10.000009
ORF1ab/nsp13166S166StcAtcG11B.1.1.10.000327
ORF1ab/nsp13166S166StcAtcG11B.1.1.1700.001247
ORF1ab/nsp13166S166StcAtcG11B.1.1.2160.00089
ORF1ab/nsp13166S166StcAtcC11B.1.1.700.000341
ORF1ab/nsp13166S166StcAtcG11B.1.1600.000031
ORF1ab/nsp13166S166StcAtcC11B.1.177.150.000631
ORF1ab/nsp13166S166StcAtcG11B.1.177.210.000076
ORF1ab/nsp13166S166StcAtcG11B.1.177.350.000691
ORF1ab/nsp13166S166StcAtcG11B.1.2370.004975
ORF1ab/nsp13166S166StcAtcG11B.1.2400.000216
ORF1ab/nsp13166S166StcAtcC11B.1.2430.00007
ORF1ab/nsp13166S166StcAtcG11B.1.4270.00005
ORF1ab/nsp13166S166StcAtcG11B.1.4290.000024
ORF1ab/nsp13166S166StcAtcG11B.1.60.017241
ORF1ab/nsp13166S166StcAtcG11B.1.6090.000479
ORF1ab/nsp13166S166StcAtcC11N.40.004255
ORF1ab/nsp13166S166StcAtcG11P.1.120.000484
ORF1ab/nsp13166S166StcAtcG11P.20.000187
ORF1ab/nsp13166S166StcAtcG11P.70.004367

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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