CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : Mut = R337R

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13337R337RR5661RsyncgTcgC285726690.93419717245-17247
ORF1ab/nsp13337R337RR5661RsyncgTcgA28571010.035351817245-17247
ORF1ab/nsp13337R337RR5661RsyncgTcgG2857870.030451517245-17247

Details of the mutation R337R within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13337R337RcgTcgC26692857All0.00051
ORF1ab/nsp13337R337RcgTcgA1012857All0.000019
ORF1ab/nsp13337R337RcgTcgG872857All0.000017
ORF1ab/nsp13337R337RcgTcgC15091516B0.192868
ORF1ab/nsp13337R337RcgTcgG71516B0.000895
ORF1ab/nsp13337R337RcgTcgC423423B.390.986014
ORF1ab/nsp13337R337RcgTcgC125125B.350.976562
ORF1ab/nsp13337R337RcgTcgA86120B.1.1.70.000077
ORF1ab/nsp13337R337RcgTcgC32120B.1.1.70.000029
ORF1ab/nsp13337R337RcgTcgG2120B.1.1.70.000002
ORF1ab/nsp13337R337RcgTcgC9898B.581
ORF1ab/nsp13337R337RcgTcgC7272B.340.986301
ORF1ab/nsp13337R337RcgTcgC5359AY.40.000082
ORF1ab/nsp13337R337RcgTcgG559AY.40.000008
ORF1ab/nsp13337R337RcgTcgA159AY.40.000002
ORF1ab/nsp13337R337RcgTcgC4747B.331
ORF1ab/nsp13337R337RcgTcgG4143AY.250.000247
ORF1ab/nsp13337R337RcgTcgC243AY.250.000012
ORF1ab/nsp13337R337RcgTcgC4242B.381
ORF1ab/nsp13337R337RcgTcgC4040AY.530.011501
ORF1ab/nsp13337R337RcgTcgC3737B.321
ORF1ab/nsp13337R337RcgTcgC3030B.370.857143
ORF1ab/nsp13337R337RcgTcgG2222AY.1100.002479
ORF1ab/nsp13337R337RcgTcgC1617B.1.20.000141
ORF1ab/nsp13337R337RcgTcgG117B.1.20.000009
ORF1ab/nsp13337R337RcgTcgC1516B.10.000137
ORF1ab/nsp13337R337RcgTcgA116B.10.000009
ORF1ab/nsp13337R337RcgTcgC1115B.1.617.20.000041
ORF1ab/nsp13337R337RcgTcgA315B.1.617.20.000011
ORF1ab/nsp13337R337RcgTcgG115B.1.617.20.000004
ORF1ab/nsp13337R337RcgTcgC1313P.10.000205
ORF1ab/nsp13337R337RcgTcgC1010B.360.769231
ORF1ab/nsp13337R337RcgTcgC79AY.30.00007
ORF1ab/nsp13337R337RcgTcgG29AY.30.00002
ORF1ab/nsp13337R337RcgTcgC88B.1.360.001167
ORF1ab/nsp13337R337RcgTcgC67AY.430.000027
ORF1ab/nsp13337R337RcgTcgG17AY.430.000004
ORF1ab/nsp13337R337RcgTcgC77B.1.10.000127
ORF1ab/nsp13337R337RcgTcgA46AY.1030.000025
ORF1ab/nsp13337R337RcgTcgC26AY.1030.000012
ORF1ab/nsp13337R337RcgTcgC66B.1.177.70.000989
ORF1ab/nsp13337R337RcgTcgC44B.1.1.5190.000159
ORF1ab/nsp13337R337RcgTcgC33AY.680.000821
ORF1ab/nsp13337R337RcgTcgA23B.1.4290.000047
ORF1ab/nsp13337R337RcgTcgC13B.1.4290.000024
ORF1ab/nsp13337R337RcgTcgC22AY.1210.000271
ORF1ab/nsp13337R337RcgTcgC22AY.230.000139
ORF1ab/nsp13337R337RcgTcgC22AY.290.000032
ORF1ab/nsp13337R337RcgTcgC12AY.390.000025
ORF1ab/nsp13337R337RcgTcgG12AY.390.000025
ORF1ab/nsp13337R337RcgTcgC12AY.440.000006
ORF1ab/nsp13337R337RcgTcgA12AY.440.000006
ORF1ab/nsp13337R337RcgTcgC22AY.840.000875
ORF1ab/nsp13337R337RcgTcgC22B.1.1.4480.004065
ORF1ab/nsp13337R337RcgTcgC22B.1.2210.000142
ORF1ab/nsp13337R337RcgTcgC22B.1.5260.000047
ORF1ab/nsp13337R337RcgTcgC22B.550.0059
ORF1ab/nsp13337R337RcgTcgC11A0.000387
ORF1ab/nsp13337R337RcgTcgC11A.20.000662
ORF1ab/nsp13337R337RcgTcgC11A.2.30.004739
ORF1ab/nsp13337R337RcgTcgC11A.220.066667
ORF1ab/nsp13337R337RcgTcgC11AU.10.001266
ORF1ab/nsp13337R337RcgTcgC11AY.240.000431
ORF1ab/nsp13337R337RcgTcgC11AY.260.000028
ORF1ab/nsp13337R337RcgTcgC11AY.330.000067
ORF1ab/nsp13337R337RcgTcgC11AY.4.20.000022
ORF1ab/nsp13337R337RcgTcgG11AY.4.50.000107
ORF1ab/nsp13337R337RcgTcgC11AY.420.00004
ORF1ab/nsp13337R337RcgTcgC11AY.50.000021
ORF1ab/nsp13337R337RcgTcgC11AY.700.000209
ORF1ab/nsp13337R337RcgTcgG11AY.940.000443
ORF1ab/nsp13337R337RcgTcgC11B.1.1.1360.021277
ORF1ab/nsp13337R337RcgTcgC11B.1.1.2980.000862
ORF1ab/nsp13337R337RcgTcgC11B.1.1.3720.000689
ORF1ab/nsp13337R337RcgTcgC11B.1.1.3970.002252
ORF1ab/nsp13337R337RcgTcgG11B.1.1600.000031
ORF1ab/nsp13337R337RcgTcgC11B.1.2150.009615
ORF1ab/nsp13337R337RcgTcgA11B.1.2320.000537
ORF1ab/nsp13337R337RcgTcgC11B.1.2430.00007
ORF1ab/nsp13337R337RcgTcgC11B.1.2580.000067
ORF1ab/nsp13337R337RcgTcgC11B.1.3510.00003
ORF1ab/nsp13337R337RcgTcgC11B.1.36.380.001642
ORF1ab/nsp13337R337RcgTcgC11B.1.36.80.001
ORF1ab/nsp13337R337RcgTcgG11B.1.5250.000113
ORF1ab/nsp13337R337RcgTcgC11B.1.5610.000397
ORF1ab/nsp13337R337RcgTcgC11B.1.5900.004545
ORF1ab/nsp13337R337RcgTcgC11B.1.5960.000087
ORF1ab/nsp13337R337RcgTcgC11B.1.6270.00202
ORF1ab/nsp13337R337RcgTcgA11B.1.6370.000073
ORF1ab/nsp13337R337RcgTcgC11B.1.9.50.005682
ORF1ab/nsp13337R337RcgTcgC11B.4.70.010101
ORF1ab/nsp13337R337RcgTcgC11B.400.000364
ORF1ab/nsp13337R337RcgTcgC11B.470.020408
ORF1ab/nsp13337R337RcgTcgC11C.370.000116
ORF1ab/nsp13337R337RcgTcgC11P.20.000187
ORF1ab/nsp13337R337RcgTcgA11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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