CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : Mut = L240L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13240L240LL5564LsynCtaTta595256780.95396516954-16956
ORF1ab/nsp13240L240LL5564LsynctActG59522620.044018816954-16956
ORF1ab/nsp13240L240LL5564LsynctActT595260.0010080616954-16956
ORF1ab/nsp13240L240LL5564LsynctActC595240.00067204316954-16956
ORF1ab/nsp13240L240LL5564LsynCtATtG595220.00033602216954-16956

Details of the mutation L240L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13240L240LCtaTta56785952All0.001086
ORF1ab/nsp13240L240LctActG2625952All0.00005
ORF1ab/nsp13240L240LctActT65952All0.000001
ORF1ab/nsp13240L240LctActC45952All0.000001
ORF1ab/nsp13240L240LCtATtG25952All0
ORF1ab/nsp13240L240LCtaTta993996AY.30.009877
ORF1ab/nsp13240L240LctActG3996AY.30.00003
ORF1ab/nsp13240L240LCtaTta871959B.1.1.70.00078
ORF1ab/nsp13240L240LctActG87959B.1.1.70.000078
ORF1ab/nsp13240L240LctActT1959B.1.1.70.000001
ORF1ab/nsp13240L240LCtaTta631631P.10.009941
ORF1ab/nsp13240L240LCtaTta480494B.1.617.20.001807
ORF1ab/nsp13240L240LctActG13494B.1.617.20.000049
ORF1ab/nsp13240L240LctActC1494B.1.617.20.000004
ORF1ab/nsp13240L240LCtaTta327327AY.610.034262
ORF1ab/nsp13240L240LCtaTta208215AY.40.000324
ORF1ab/nsp13240L240LctActG6215AY.40.000009
ORF1ab/nsp13240L240LctActC1215AY.40.000002
ORF1ab/nsp13240L240LCtaTta161163AY.470.005008
ORF1ab/nsp13240L240LctActG2163AY.470.000062
ORF1ab/nsp13240L240LCtaTta138138B.1.1.3850.616071
ORF1ab/nsp13240L240LCtaTta110115AY.430.000487
ORF1ab/nsp13240L240LctActG3115AY.430.000013
ORF1ab/nsp13240L240LctActC2115AY.430.000009
ORF1ab/nsp13240L240LCtaTta106106AY.1000.004877
ORF1ab/nsp13240L240LCtaTta9292B.1.1600.002869
ORF1ab/nsp13240L240LctActG4686B.1.1770.000606
ORF1ab/nsp13240L240LCtaTta4086B.1.1770.000527
ORF1ab/nsp13240L240LCtaTta8084AY.250.000481
ORF1ab/nsp13240L240LctActG484AY.250.000024
ORF1ab/nsp13240L240LCtaTta8182B.1.3510.002408
ORF1ab/nsp13240L240LctActG182B.1.3510.00003
ORF1ab/nsp13240L240LCtaTta5872AY.1030.00036
ORF1ab/nsp13240L240LctActG1472AY.1030.000087
ORF1ab/nsp13240L240LCtaTta5657B.1.20.000493
ORF1ab/nsp13240L240LctActG157B.1.20.000009
ORF1ab/nsp13240L240LCtaTta5656B.1.1.1290.513761
ORF1ab/nsp13240L240LCtaTta4354B.10.000394
ORF1ab/nsp13240L240LctActG954B.10.000082
ORF1ab/nsp13240L240LctActT254B.10.000018
ORF1ab/nsp13240L240LCtaTta5152B.1.2210.003623
ORF1ab/nsp13240L240LctActG152B.1.2210.000071
ORF1ab/nsp13240L240LCtaTta4545AY.620.019608
ORF1ab/nsp13240L240LCtaTta3941AY.390.000964
ORF1ab/nsp13240L240LctActG241AY.390.000049
ORF1ab/nsp13240L240LCtaTta3941AY.440.000237
ORF1ab/nsp13240L240LctActG241AY.440.000012
ORF1ab/nsp13240L240LCtaTta3939B.1.5410.172566
ORF1ab/nsp13240L240LCtaTta3737AY.1130.005268
ORF1ab/nsp13240L240LCtaTta3737AY.260.001047
ORF1ab/nsp13240L240LCtaTta3535B.1.5260.000823
ORF1ab/nsp13240L240LCtaTta2828B.1.2430.001948
ORF1ab/nsp13240L240LctActG2628B.1.6090.012464
ORF1ab/nsp13240L240LCtaTta228B.1.6090.000959
ORF1ab/nsp13240L240LCtaTta2526B.1.10.000454
ORF1ab/nsp13240L240LCtATtG126B.1.10.000018
ORF1ab/nsp13240L240LCtaTta2525AY.1020.000663
ORF1ab/nsp13240L240LCtaTta2525C.36.30.01418
ORF1ab/nsp13240L240LCtaTta2323AY.4.2.10.003427
ORF1ab/nsp13240L240LCtaTta2323C.350.017802
ORF1ab/nsp13240L240LCtaTta2222AY.9.20.000808
ORF1ab/nsp13240L240LCtaTta2121B.1.6370.001535
ORF1ab/nsp13240L240LCtaTta1919AY.840.008311
ORF1ab/nsp13240L240LCtaTta1919B.1.1.330.007997
ORF1ab/nsp13240L240LCtaTta1819B.1.4290.000424
ORF1ab/nsp13240L240LctActG119B.1.4290.000024
ORF1ab/nsp13240L240LctActG1717Q.10.002148
ORF1ab/nsp13240L240LCtaTta1616AY.920.004596
ORF1ab/nsp13240L240LCtaTta1616B.1.1.2910.011878
ORF1ab/nsp13240L240LCtaTta1515AY.290.000237
ORF1ab/nsp13240L240LCtaTta1515B.1.1.3690.006693
ORF1ab/nsp13240L240LCtaTta1414AY.4.20.000304
ORF1ab/nsp13240L240LCtaTta1213AY.230.000837
ORF1ab/nsp13240L240LctActG113AY.230.00007
ORF1ab/nsp13240L240LCtaTta1313AY.460.001353
ORF1ab/nsp13240L240LCtaTta1313C.370.001509
ORF1ab/nsp13240L240LCtaTta1212AY.1180.000752
ORF1ab/nsp13240L240LCtaTta1212AY.75.10.002164
ORF1ab/nsp13240L240LCtaTta1212B.1.1.2140.000665
ORF1ab/nsp13240L240LCtaTta1010A.2.50.00499
ORF1ab/nsp13240L240LCtaTta1010AY.330.000668
ORF1ab/nsp13240L240LCtaTta1010AY.750.00056
ORF1ab/nsp13240L240LCtaTta1010B.1.1.5190.000397
ORF1ab/nsp13240L240LCtaTta99B.1.3620.013867
ORF1ab/nsp13240L240LCtaTta99L.10.017143
ORF1ab/nsp13240L240LCtaTta88AY.1190.000282
ORF1ab/nsp13240L240LCtaTta88AY.16.10.003759
ORF1ab/nsp13240L240LCtaTta88AY.200.000311
ORF1ab/nsp13240L240LCtaTta88B.1.2400.001725
ORF1ab/nsp13240L240LCtaTta88P.1.10.002541
ORF1ab/nsp13240L240LCtaTta77P.1.140.000335
ORF1ab/nsp13240L240LCtaTta47P.1.150.000929
ORF1ab/nsp13240L240LctActG37P.1.150.000697
ORF1ab/nsp13240L240LCtaTta66AY.1170.000507
ORF1ab/nsp13240L240LCtaTta66AY.360.000889
ORF1ab/nsp13240L240LCtaTta56AY.60.000206
ORF1ab/nsp13240L240LctActG16AY.60.000041
ORF1ab/nsp13240L240LCtaTta66AY.790.007264
ORF1ab/nsp13240L240LCtaTta66AY.98.10.000291
ORF1ab/nsp13240L240LCtaTta66AY.99.20.000553
ORF1ab/nsp13240L240LCtaTta66B.1.2340.000792
ORF1ab/nsp13240L240LCtaTta66B.1.617.10.000774
ORF1ab/nsp13240L240LCtaTta66R.10.00054
ORF1ab/nsp13240L240LCtaTta55A.10.001409
ORF1ab/nsp13240L240LCtaTta55AY.130.000805
ORF1ab/nsp13240L240LCtaTta55AY.160.001898
ORF1ab/nsp13240L240LCtaTta55AY.630.001934
ORF1ab/nsp13240L240LCtaTta55AY.90.000338
ORF1ab/nsp13240L240LCtaTta45B.1.5960.000349
ORF1ab/nsp13240L240LctActT15B.1.5960.000087
ORF1ab/nsp13240L240LCtaTta55B.1.6210.000443
ORF1ab/nsp13240L240LCtaTta44AY.1010.001962
ORF1ab/nsp13240L240LctActG44AY.1140.000924
ORF1ab/nsp13240L240LCtaTta24AY.420.00008
ORF1ab/nsp13240L240LctActG24AY.420.00008
ORF1ab/nsp13240L240LCtaTta44AY.50.000083
ORF1ab/nsp13240L240LCtaTta44B.1.2580.000266
ORF1ab/nsp13240L240LCtaTta44B.1.5250.000453
ORF1ab/nsp13240L240LCtaTta44B.1.5750.001214
ORF1ab/nsp13240L240LCtaTta44B.1.6310.013468
ORF1ab/nsp13240L240LCtaTta44D.20.0003
ORF1ab/nsp13240L240LCtaTta130.055556
ORF1ab/nsp13240L240LCtATtG130.055556
ORF1ab/nsp13240L240LctActG130.055556
ORF1ab/nsp13240L240LCtaTta33A.210.00831
ORF1ab/nsp13240L240LCtaTta33AY.1200.000112
ORF1ab/nsp13240L240LCtaTta33AY.140.000264
ORF1ab/nsp13240L240LCtaTta33AY.240.001293
ORF1ab/nsp13240L240LCtaTta33AY.46.60.000217
ORF1ab/nsp13240L240LCtaTta33AY.540.000286
ORF1ab/nsp13240L240LCtaTta23AY.590.001059
ORF1ab/nsp13240L240LctActG13AY.590.00053
ORF1ab/nsp13240L240LCtaTta33AY.650.001599
ORF1ab/nsp13240L240LCtaTta33AY.740.000347
ORF1ab/nsp13240L240LCtaTta33AY.9.10.000251
ORF1ab/nsp13240L240LCtaTta33B.1.1.2160.002671
ORF1ab/nsp13240L240LCtaTta33B.1.1.270.016949
ORF1ab/nsp13240L240LCtaTta33B.1.1.280.000934
ORF1ab/nsp13240L240LCtaTta23B.1.1.3060.000877
ORF1ab/nsp13240L240LctActG13B.1.1.3060.000438
ORF1ab/nsp13240L240LCtaTta33B.1.1.370.000579
ORF1ab/nsp13240L240LCtaTta33B.1.1.3890.018182
ORF1ab/nsp13240L240LCtaTta33B.1.110.30.002155
ORF1ab/nsp13240L240LCtaTta33B.1.1390.002199
ORF1ab/nsp13240L240LCtaTta33B.1.177.80.002257
ORF1ab/nsp13240L240LCtaTta33B.1.221.10.008721
ORF1ab/nsp13240L240LCtaTta33B.1.258.170.000312
ORF1ab/nsp13240L240LCtaTta33P.1.120.001452
ORF1ab/nsp13240L240LCtaTta33P.60.009434
ORF1ab/nsp13240L240LCtaTta22AY.1100.000225
ORF1ab/nsp13240L240LCtaTta22AY.120.10.000642
ORF1ab/nsp13240L240LCtaTta22AY.120.20.002571
ORF1ab/nsp13240L240LCtaTta22AY.3.10.000171
ORF1ab/nsp13240L240LCtaTta12AY.320.000532
ORF1ab/nsp13240L240LctActG12AY.320.000532
ORF1ab/nsp13240L240LctActG12AY.350.000233
ORF1ab/nsp13240L240LCtaTta12AY.350.000233
ORF1ab/nsp13240L240LCtaTta22AY.5.30.000675
ORF1ab/nsp13240L240LCtaTta22AY.520.001629
ORF1ab/nsp13240L240LCtaTta22AY.550.001835
ORF1ab/nsp13240L240LCtaTta12AY.680.000274
ORF1ab/nsp13240L240LctActG12AY.680.000274
ORF1ab/nsp13240L240LCtaTta22AY.700.000417
ORF1ab/nsp13240L240LCtaTta22AY.730.001331
ORF1ab/nsp13240L240LCtaTta22AY.820.002714
ORF1ab/nsp13240L240LCtaTta22AY.990.002099
ORF1ab/nsp13240L240LCtaTta22B.1.1.10.000653
ORF1ab/nsp13240L240LCtaTta22B.1.1.250.001137
ORF1ab/nsp13240L240LCtaTta22B.1.177.600.000437
ORF1ab/nsp13240L240LCtaTta22B.1.177.610.086957
ORF1ab/nsp13240L240LctActG12B.1.177.70.000165
ORF1ab/nsp13240L240LCtaTta12B.1.177.70.000165
ORF1ab/nsp13240L240LCtaTta22B.1.4220.001625
ORF1ab/nsp13240L240LCtaTta22B.1.4260.002018
ORF1ab/nsp13240L240LCtaTta22B.1.4270.000101
ORF1ab/nsp13240L240LCtaTta22B.1.4590.008163
ORF1ab/nsp13240L240LCtaTta22B.1.5770.001375
ORF1ab/nsp13240L240LCtaTta22B.400.000729
ORF1ab/nsp13240L240LCtaTta12P.1.100.000269
ORF1ab/nsp13240L240LctActG12P.1.100.000269
ORF1ab/nsp13240L240LCtaTta22P.1.130.001797
ORF1ab/nsp13240L240LctActG22Q.40.00091
ORF1ab/nsp13240L240LCtaTta22W.40.002703
ORF1ab/nsp13240L240LCtaTta11A0.000387
ORF1ab/nsp13240L240LCtaTta11AH.30.003802
ORF1ab/nsp13240L240LCtaTta11AY.1210.000135
ORF1ab/nsp13240L240LCtaTta11AY.300.000396
ORF1ab/nsp13240L240LCtaTta11AY.39.20.001541
ORF1ab/nsp13240L240LCtaTta11AY.4.40.000409
ORF1ab/nsp13240L240LCtaTta11AY.4.50.000107
ORF1ab/nsp13240L240LCtaTta11AY.450.000122
ORF1ab/nsp13240L240LCtaTta11AY.480.000465
ORF1ab/nsp13240L240LCtaTta11AY.5.40.000277
ORF1ab/nsp13240L240LCtaTta11AY.530.000288
ORF1ab/nsp13240L240LCtaTta11AY.560.001605
ORF1ab/nsp13240L240LctActG11AY.70.000196
ORF1ab/nsp13240L240LCtaTta11AY.710.000475
ORF1ab/nsp13240L240LCtaTta11AY.760.004831
ORF1ab/nsp13240L240LCtaTta11AY.860.00083
ORF1ab/nsp13240L240LCtaTta11AY.880.000884
ORF1ab/nsp13240L240LCtaTta11AY.930.000273
ORF1ab/nsp13240L240LCtaTta11AY.940.000443
ORF1ab/nsp13240L240LCtaTta11AZ.40.003356
ORF1ab/nsp13240L240LCtaTta11B0.000128
ORF1ab/nsp13240L240LCtaTta11B.1.1.100.001115
ORF1ab/nsp13240L240LCtaTta11B.1.1.1280.007092
ORF1ab/nsp13240L240LCtaTta11B.1.1.2070.001182
ORF1ab/nsp13240L240LCtaTta11B.1.1.2220.000204
ORF1ab/nsp13240L240LCtaTta11B.1.1.2370.005405
ORF1ab/nsp13240L240LCtaTta11B.1.1.2560.013699
ORF1ab/nsp13240L240LctActT11B.1.1.2770.000759
ORF1ab/nsp13240L240LCtaTta11B.1.1.3050.003861
ORF1ab/nsp13240L240LctActG11B.1.1.3110.000358
ORF1ab/nsp13240L240LCtaTta11B.1.1.3170.000412
ORF1ab/nsp13240L240LCtaTta11B.1.1.3290.003846
ORF1ab/nsp13240L240LCtaTta11B.1.1.3680.003086
ORF1ab/nsp13240L240LCtaTta11B.1.1.390.00051
ORF1ab/nsp13240L240LCtaTta11B.1.1.3970.002252
ORF1ab/nsp13240L240LCtaTta11B.1.1.4200.001006
ORF1ab/nsp13240L240LCtaTta11B.1.1.4400.011765
ORF1ab/nsp13240L240LCtaTta11B.1.1.4480.002033
ORF1ab/nsp13240L240LCtaTta11B.1.1.5260.003546
ORF1ab/nsp13240L240LCtaTta11B.1.1.5280.004808
ORF1ab/nsp13240L240LctActG11B.1.1280.000635
ORF1ab/nsp13240L240LCtaTta11B.1.1570.002985
ORF1ab/nsp13240L240LCtaTta11B.1.160.160.000929
ORF1ab/nsp13240L240LCtaTta11B.1.177.210.000076
ORF1ab/nsp13240L240LCtaTta11B.1.177.40.000211
ORF1ab/nsp13240L240LCtaTta11B.1.177.440.000519
ORF1ab/nsp13240L240LCtaTta11B.1.177.520.001757
ORF1ab/nsp13240L240LCtaTta11B.1.177.570.000281
ORF1ab/nsp13240L240LCtaTta11B.1.177.690.001484
ORF1ab/nsp13240L240LCtaTta11B.1.177.810.000189
ORF1ab/nsp13240L240LCtaTta11B.1.177.840.006667
ORF1ab/nsp13240L240LCtaTta11B.1.1790.003759
ORF1ab/nsp13240L240LCtaTta11B.1.2130.014925
ORF1ab/nsp13240L240LCtaTta11B.1.2220.001692
ORF1ab/nsp13240L240LCtaTta11B.1.2410.000812
ORF1ab/nsp13240L240LCtaTta11B.1.2940.032258
ORF1ab/nsp13240L240LCtaTta11B.1.3110.000275
ORF1ab/nsp13240L240LCtaTta11B.1.351.20.000303
ORF1ab/nsp13240L240LCtaTta11B.1.360.000146
ORF1ab/nsp13240L240LCtaTta11B.1.36.160.001425
ORF1ab/nsp13240L240LCtaTta11B.1.36.290.000517
ORF1ab/nsp13240L240LCtaTta11B.1.36.80.001
ORF1ab/nsp13240L240LCtaTta11B.1.3610.001289
ORF1ab/nsp13240L240LCtaTta11B.1.3750.00082
ORF1ab/nsp13240L240LCtaTta11B.1.4020.009804
ORF1ab/nsp13240L240LCtaTta11B.1.4250.002994
ORF1ab/nsp13240L240LCtaTta11B.1.4280.00102
ORF1ab/nsp13240L240LCtaTta11B.1.4700.001404
ORF1ab/nsp13240L240LCtaTta11B.1.4710.002732
ORF1ab/nsp13240L240LctActT11B.1.4790.038462
ORF1ab/nsp13240L240LCtaTta11B.1.5090.000866
ORF1ab/nsp13240L240LCtaTta11B.1.5170.000427
ORF1ab/nsp13240L240LCtaTta11B.1.5240.001406
ORF1ab/nsp13240L240LCtaTta11B.1.5510.00129
ORF1ab/nsp13240L240LCtaTta11B.1.5950.000261
ORF1ab/nsp13240L240LCtaTta11B.1.619.10.000641
ORF1ab/nsp13240L240LCtaTta11B.1.6280.000352
ORF1ab/nsp13240L240LCtaTta11B.1.780.008547
ORF1ab/nsp13240L240LCtaTta11B.3.10.001658
ORF1ab/nsp13240L240LCtaTta11C.360.000911
ORF1ab/nsp13240L240LCtaTta11C.390.018868
ORF1ab/nsp13240L240LCtaTta11L.20.011364
ORF1ab/nsp13240L240LCtaTta11P.1.170.000162
ORF1ab/nsp13240L240LCtaTta11P.1.20.001156
ORF1ab/nsp13240L240LCtaTta11Q.30.000145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.