CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : Mut = L158M

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13158L158ML5482MnonsynCtgAtg6969116708-16710

Details of the mutation L158M within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13158L158MCtgAtg6969All0.000013
ORF1ab/nsp13158L158MCtgAtg1515B.1.4290.000353
ORF1ab/nsp13158L158MCtgAtg77B.1.5610.002779
ORF1ab/nsp13158L158MCtgAtg66B.1.3510.000178
ORF1ab/nsp13158L158MCtgAtg55AY.250.00003
ORF1ab/nsp13158L158MCtgAtg55B.1.617.20.000019
ORF1ab/nsp13158L158MCtgAtg44B.1.1.1410.008048
ORF1ab/nsp13158L158MCtgAtg33AY.10.001187
ORF1ab/nsp13158L158MCtgAtg22AY.4.50.000215
ORF1ab/nsp13158L158MCtgAtg22AY.98.10.000097
ORF1ab/nsp13158L158MCtgAtg22B.1.1.70.000002
ORF1ab/nsp13158L158MCtgAtg22B.1.2430.000139
ORF1ab/nsp13158L158MCtgAtg11A.2.40.003367
ORF1ab/nsp13158L158MCtgAtg11AY.1020.000027
ORF1ab/nsp13158L158MCtgAtg11AY.1050.000643
ORF1ab/nsp13158L158MCtgAtg11AY.120.20.001285
ORF1ab/nsp13158L158MCtgAtg11AY.30.00001
ORF1ab/nsp13158L158MCtgAtg11AY.330.000067
ORF1ab/nsp13158L158MCtgAtg11AY.680.000274
ORF1ab/nsp13158L158MCtgAtg11B.10.000009
ORF1ab/nsp13158L158MCtgAtg11B.1.10.000018
ORF1ab/nsp13158L158MCtgAtg11B.1.1600.000031
ORF1ab/nsp13158L158MCtgAtg11B.1.20.000009
ORF1ab/nsp13158L158MCtgAtg11B.1.2580.000067
ORF1ab/nsp13158L158MCtgAtg11B.1.4700.001404
ORF1ab/nsp13158L158MCtgAtg11B.1.5260.000024
ORF1ab/nsp13158L158MCtgAtg11B.1.5820.000491
ORF1ab/nsp13158L158MCtgAtg11P.10.000016

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.