CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : Mut = K524N

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13524K524NK5848NnonsynaaGaaT10459780.93588517806-17808
ORF1ab/nsp13524K524NK5848NnonsynaaGaaC1045670.064114817806-17808

Details of the mutation K524N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13524K524NaaGaaT9781045All0.000187
ORF1ab/nsp13524K524NaaGaaC671045All0.000013
ORF1ab/nsp13524K524NaaGaaT110124AY.40.000171
ORF1ab/nsp13524K524NaaGaaC14124AY.40.000022
ORF1ab/nsp13524K524NaaGaaT9294B.1.1.70.000082
ORF1ab/nsp13524K524NaaGaaC294B.1.1.70.000002
ORF1ab/nsp13524K524NaaGaaT8888B.1.4501
ORF1ab/nsp13524K524NaaGaaT7478AY.440.00045
ORF1ab/nsp13524K524NaaGaaC478AY.440.000024
ORF1ab/nsp13524K524NaaGaaT6363B.1.1.5190.002502
ORF1ab/nsp13524K524NaaGaaT3649AY.250.000217
ORF1ab/nsp13524K524NaaGaaC1349AY.250.000078
ORF1ab/nsp13524K524NaaGaaT4247B.1.617.20.000158
ORF1ab/nsp13524K524NaaGaaC547B.1.617.20.000019
ORF1ab/nsp13524K524NaaGaaT3637B.10.00033
ORF1ab/nsp13524K524NaaGaaC137B.10.000009
ORF1ab/nsp13524K524NaaGaaT2025AY.430.000089
ORF1ab/nsp13524K524NaaGaaC525AY.430.000022
ORF1ab/nsp13524K524NaaGaaT2122AY.30.000209
ORF1ab/nsp13524K524NaaGaaC122AY.30.00001
ORF1ab/nsp13524K524NaaGaaT1919B.1.1.390.009684
ORF1ab/nsp13524K524NaaGaaT1617AY.4.20.000347
ORF1ab/nsp13524K524NaaGaaC117AY.4.20.000022
ORF1ab/nsp13524K524NaaGaaT1717B.1.10.000308
ORF1ab/nsp13524K524NaaGaaT1616B.1.20.000141
ORF1ab/nsp13524K524NaaGaaT1515AY.1060.005023
ORF1ab/nsp13524K524NaaGaaT1213AY.1030.000075
ORF1ab/nsp13524K524NaaGaaC113AY.1030.000006
ORF1ab/nsp13524K524NaaGaaT1111B.1.2210.000781
ORF1ab/nsp13524K524NaaGaaT1010AY.470.000311
ORF1ab/nsp13524K524NaaGaaT1010AY.50.000206
ORF1ab/nsp13524K524NaaGaaT1010B.1.1770.000132
ORF1ab/nsp13524K524NaaGaaT89AY.290.000126
ORF1ab/nsp13524K524NaaGaaC19AY.290.000016
ORF1ab/nsp13524K524NaaGaaT99AY.39.10.000357
ORF1ab/nsp13524K524NaaGaaT88AY.1180.000501
ORF1ab/nsp13524K524NaaGaaT88AY.120.10.002568
ORF1ab/nsp13524K524NaaGaaT88AY.98.10.000387
ORF1ab/nsp13524K524NaaGaaT77AY.9.10.000586
ORF1ab/nsp13524K524NaaGaaT77P.10.00011
ORF1ab/nsp13524K524NaaGaaT66AY.330.000401
ORF1ab/nsp13524K524NaaGaaT66AY.4.50.000645
ORF1ab/nsp13524K524NaaGaaT66AY.5.30.002024
ORF1ab/nsp13524K524NaaGaaT66AY.900.004107
ORF1ab/nsp13524K524NaaGaaT66B.1.1.2140.000333
ORF1ab/nsp13524K524NaaGaaT66B.1.1.2220.001224
ORF1ab/nsp13524K524NaaGaaT66B.1.1.330.002525
ORF1ab/nsp13524K524NaaGaaC46B.1.2430.000278
ORF1ab/nsp13524K524NaaGaaT26B.1.2430.000139
ORF1ab/nsp13524K524NaaGaaT55AY.1020.000133
ORF1ab/nsp13524K524NaaGaaT45AY.420.000161
ORF1ab/nsp13524K524NaaGaaC15AY.420.00004
ORF1ab/nsp13524K524NaaGaaT55AY.90.000338
ORF1ab/nsp13524K524NaaGaaT44AY.1190.000141
ORF1ab/nsp13524K524NaaGaaT44AY.200.000155
ORF1ab/nsp13524K524NaaGaaT44AY.270.000259
ORF1ab/nsp13524K524NaaGaaT44AY.4.2.10.000596
ORF1ab/nsp13524K524NaaGaaT44B.1.1.3480.003185
ORF1ab/nsp13524K524NaaGaaT44B.1.36.10.004561
ORF1ab/nsp13524K524NaaGaaT44B.1.4290.000094
ORF1ab/nsp13524K524NaaGaaT33AY.1200.000112
ORF1ab/nsp13524K524NaaGaaT33AY.530.000863
ORF1ab/nsp13524K524NaaGaaT33AY.700.000626
ORF1ab/nsp13524K524NaaGaaT33AY.99.20.000276
ORF1ab/nsp13524K524NaaGaaT33B0.000383
ORF1ab/nsp13524K524NaaGaaT33B.1.221.40.0125
ORF1ab/nsp13524K524NaaGaaC33B.1.3510.000089
ORF1ab/nsp13524K524NaaGaaT33B.1.4270.000151
ORF1ab/nsp13524K524NaaGaaT33B.1.5260.000071
ORF1ab/nsp13524K524NaaGaaC23B.1.5960.000174
ORF1ab/nsp13524K524NaaGaaT13B.1.5960.000087
ORF1ab/nsp13524K524NaaGaaT33C.370.000348
ORF1ab/nsp13524K524NaaGaaT33D.20.000225
ORF1ab/nsp13524K524NaaGaaT22AD.20.000438
ORF1ab/nsp13524K524NaaGaaT22AY.1000.000092
ORF1ab/nsp13524K524NaaGaaT22AY.120.2.10.000997
ORF1ab/nsp13524K524NaaGaaT22AY.360.000296
ORF1ab/nsp13524K524NaaGaaT22AY.450.000243
ORF1ab/nsp13524K524NaaGaaT22AY.560.00321
ORF1ab/nsp13524K524NaaGaaT22AY.60.000082
ORF1ab/nsp13524K524NaaGaaT22AY.9.20.000073
ORF1ab/nsp13524K524NaaGaaT22AY.980.000158
ORF1ab/nsp13524K524NaaGaaC22B.1.1.2290.011494
ORF1ab/nsp13524K524NaaGaaT22B.1.1.3400.090909
ORF1ab/nsp13524K524NaaGaaT22B.1.110.30.001437
ORF1ab/nsp13524K524NaaGaaT22B.1.1600.000062
ORF1ab/nsp13524K524NaaGaaT12B.1.177.860.000183
ORF1ab/nsp13524K524NaaGaaC12B.1.177.860.000183
ORF1ab/nsp13524K524NaaGaaT22B.1.2400.000431
ORF1ab/nsp13524K524NaaGaaT22B.1.258.110.000793
ORF1ab/nsp13524K524NaaGaaT22B.1.4090.001563
ORF1ab/nsp13524K524NaaGaaT11A0.000387
ORF1ab/nsp13524K524NaaGaaC11A.20.000662
ORF1ab/nsp13524K524NaaGaaT11A.2.5.30.010309
ORF1ab/nsp13524K524NaaGaaT11AY.1130.000142
ORF1ab/nsp13524K524NaaGaaT11AY.1170.000085
ORF1ab/nsp13524K524NaaGaaT11AY.1210.000135
ORF1ab/nsp13524K524NaaGaaT11AY.260.000028
ORF1ab/nsp13524K524NaaGaaT11AY.320.000532
ORF1ab/nsp13524K524NaaGaaT11AY.350.000233
ORF1ab/nsp13524K524NaaGaaT11AY.390.000025
ORF1ab/nsp13524K524NaaGaaT11AY.39.1.10.000725
ORF1ab/nsp13524K524NaaGaaT11AY.4.40.000409
ORF1ab/nsp13524K524NaaGaaT11AY.580.000907
ORF1ab/nsp13524K524NaaGaaT11AY.590.00053
ORF1ab/nsp13524K524NaaGaaT11AY.600.000938
ORF1ab/nsp13524K524NaaGaaT11AY.780.001541
ORF1ab/nsp13524K524NaaGaaC11AY.80.000606
ORF1ab/nsp13524K524NaaGaaT11AY.800.001129
ORF1ab/nsp13524K524NaaGaaT11AY.810.001992
ORF1ab/nsp13524K524NaaGaaT11AY.930.000273
ORF1ab/nsp13524K524NaaGaaT11AY.940.000443
ORF1ab/nsp13524K524NaaGaaT11AZ.10.000867
ORF1ab/nsp13524K524NaaGaaT11B.1.1.1580.012195
ORF1ab/nsp13524K524NaaGaaT11B.1.1.2310.003096
ORF1ab/nsp13524K524NaaGaaT11B.1.1.250.000569
ORF1ab/nsp13524K524NaaGaaT11B.1.1.2530.002506
ORF1ab/nsp13524K524NaaGaaT11B.1.1.280.000311
ORF1ab/nsp13524K524NaaGaaT11B.1.1.3690.000446
ORF1ab/nsp13524K524NaaGaaT11B.1.1.380.058824
ORF1ab/nsp13524K524NaaGaaT11B.1.1110.001175
ORF1ab/nsp13524K524NaaGaaT11B.1.160.160.000929
ORF1ab/nsp13524K524NaaGaaT11B.1.160.80.001289
ORF1ab/nsp13524K524NaaGaaT11B.1.177.210.000076
ORF1ab/nsp13524K524NaaGaaT11B.1.177.400.005155
ORF1ab/nsp13524K524NaaGaaT11B.1.177.750.001041
ORF1ab/nsp13524K524NaaGaaT11B.1.1900.01
ORF1ab/nsp13524K524NaaGaaC11B.1.2330.014085
ORF1ab/nsp13524K524NaaGaaT11B.1.2340.000132
ORF1ab/nsp13524K524NaaGaaT11B.1.2580.000067
ORF1ab/nsp13524K524NaaGaaT11B.1.3050.002151
ORF1ab/nsp13524K524NaaGaaT11B.1.3110.000275
ORF1ab/nsp13524K524NaaGaaT11B.1.360.000146
ORF1ab/nsp13524K524NaaGaaT11B.1.36.120.009615
ORF1ab/nsp13524K524NaaGaaC11B.1.3610.001289
ORF1ab/nsp13524K524NaaGaaT11B.1.3670.000792
ORF1ab/nsp13524K524NaaGaaT11B.1.3710.001122
ORF1ab/nsp13524K524NaaGaaT11B.1.4040.001302
ORF1ab/nsp13524K524NaaGaaT11B.1.4160.001269
ORF1ab/nsp13524K524NaaGaaT11B.1.438.10.000107
ORF1ab/nsp13524K524NaaGaaT11B.1.5170.000427
ORF1ab/nsp13524K524NaaGaaT11B.1.5740.002151
ORF1ab/nsp13524K524NaaGaaT11B.1.5880.00091
ORF1ab/nsp13524K524NaaGaaT11B.1.595.40.007299
ORF1ab/nsp13524K524NaaGaaT11B.1.6090.000479
ORF1ab/nsp13524K524NaaGaaT11B.230.002924
ORF1ab/nsp13524K524NaaGaaT11B.30.000831
ORF1ab/nsp13524K524NaaGaaT11B.310.003731
ORF1ab/nsp13524K524NaaGaaC11P.1.10.000318
ORF1ab/nsp13524K524NaaGaaC11P.1.140.000048
ORF1ab/nsp13524K524NaaGaaT11P.20.000187
ORF1ab/nsp13524K524NaaGaaT11Q.30.000145
ORF1ab/nsp13524K524NaaGaaT11Q.40.000455
ORF1ab/nsp13524K524NaaGaaT11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.