CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : Mut = K460N

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13460K460NK5784NnonsynaaGaaT65570.87692317614-17616
ORF1ab/nsp13460K460NK5784NnonsynaaGaaC6580.12307717614-17616

Details of the mutation K460N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13460K460NaaGaaT5765All0.000011
ORF1ab/nsp13460K460NaaGaaC865All0.000002
ORF1ab/nsp13460K460NaaGaaT1214B.10.00011
ORF1ab/nsp13460K460NaaGaaC214B.10.000018
ORF1ab/nsp13460K460NaaGaaT1010AY.1200.000372
ORF1ab/nsp13460K460NaaGaaT56B.1.617.20.000019
ORF1ab/nsp13460K460NaaGaaC16B.1.617.20.000004
ORF1ab/nsp13460K460NaaGaaT45B.1.1.70.000004
ORF1ab/nsp13460K460NaaGaaC15B.1.1.70.000001
ORF1ab/nsp13460K460NaaGaaT55P.1.140.000239
ORF1ab/nsp13460K460NaaGaaT44AY.610.000419
ORF1ab/nsp13460K460NaaGaaT220.111111
ORF1ab/nsp13460K460NaaGaaC22AY.1130.000285
ORF1ab/nsp13460K460NaaGaaT22AY.290.000032
ORF1ab/nsp13460K460NaaGaaT11AY.1000.000046
ORF1ab/nsp13460K460NaaGaaT11AY.1020.000027
ORF1ab/nsp13460K460NaaGaaT11AY.160.00038
ORF1ab/nsp13460K460NaaGaaT11AY.250.000006
ORF1ab/nsp13460K460NaaGaaT11AY.40.000002
ORF1ab/nsp13460K460NaaGaaT11AY.430.000004
ORF1ab/nsp13460K460NaaGaaT11AY.470.000031
ORF1ab/nsp13460K460NaaGaaT11AY.840.000437
ORF1ab/nsp13460K460NaaGaaT11B.1.1770.000013
ORF1ab/nsp13460K460NaaGaaT11B.1.2580.000067
ORF1ab/nsp13460K460NaaGaaC11B.1.258.170.000104
ORF1ab/nsp13460K460NaaGaaC11B.1.5820.000491
ORF1ab/nsp13460K460NaaGaaT11B.1.5900.004545
ORF1ab/nsp13460K460NaaGaaT11D.20.000075
ORF1ab/nsp13460K460NaaGaaT11P.20.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.