CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : Mut = C50R

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp1350C50RC5374RnonsynTgcCgc18140.77777816384-16386
ORF1ab/nsp1350C50RC5374RnonsynTgCCgA1820.11111116384-16386
ORF1ab/nsp1350C50RC5374RnonsynTgCCgG1820.11111116384-16386

Details of the mutation C50R within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp1350C50RTgcCgc1418All0.000003
ORF1ab/nsp1350C50RTgCCgG218All0
ORF1ab/nsp1350C50RTgCCgA218All0
ORF1ab/nsp1350C50RTgcCgc260.111111
ORF1ab/nsp1350C50RTgCCgA260.111111
ORF1ab/nsp1350C50RTgCCgG260.111111
ORF1ab/nsp1350C50RTgcCgc33B.10.000027
ORF1ab/nsp1350C50RTgcCgc11AY.230.00007
ORF1ab/nsp1350C50RTgcCgc11AY.4.50.000107
ORF1ab/nsp1350C50RTgcCgc11B.1.1.390.00051
ORF1ab/nsp1350C50RTgcCgc11B.1.1.70.000001
ORF1ab/nsp1350C50RTgcCgc11B.1.1770.000013
ORF1ab/nsp1350C50RTgcCgc11B.1.36.190.009259
ORF1ab/nsp1350C50RTgcCgc11B.1.5960.000087
ORF1ab/nsp1350C50RTgcCgc11B.60.00091
ORF1ab/nsp1350C50RTgcCgc11D.20.000075

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.