CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : Mut = A368S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13368A368SA5692SnonsynGcaTca24372437117338-17340

Details of the mutation A368S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13368A368SGcaTca24372437All0.000466
ORF1ab/nsp13368A368SGcaTca466466B.1.617.10.060098
ORF1ab/nsp13368A368SGcaTca258258AY.390.006376
ORF1ab/nsp13368A368SGcaTca215215B.1.1.70.000192
ORF1ab/nsp13368A368SGcaTca202202AY.40.000314
ORF1ab/nsp13368A368SGcaTca148148AY.1030.000919
ORF1ab/nsp13368A368SGcaTca133133B.1.617.20.000501
ORF1ab/nsp13368A368SGcaTca121121AY.50.002499
ORF1ab/nsp13368A368SGcaTca9292AY.250.000553
ORF1ab/nsp13368A368SGcaTca8181B.1.5960.007058
ORF1ab/nsp13368A368SGcaTca7474AY.1190.002613
ORF1ab/nsp13368A368SGcaTca4747B.1.1770.000619
ORF1ab/nsp13368A368SGcaTca4141AY.430.000182
ORF1ab/nsp13368A368SGcaTca3535AY.4.20.000759
ORF1ab/nsp13368A368SGcaTca3030AY.1020.000795
ORF1ab/nsp13368A368SGcaTca2929B.10.000266
ORF1ab/nsp13368A368SGcaTca2727AY.270.001747
ORF1ab/nsp13368A368SGcaTca2424AY.440.000146
ORF1ab/nsp13368A368SGcaTca2222AY.46.60.001589
ORF1ab/nsp13368A368SGcaTca2121B.1.1.500.014257
ORF1ab/nsp13368A368SGcaTca2020AY.610.002096
ORF1ab/nsp13368A368SGcaTca1818B.1.10.000327
ORF1ab/nsp13368A368SGcaTca1616AY.1080.017641
ORF1ab/nsp13368A368SGcaTca1414P.40.053232
ORF1ab/nsp13368A368SGcaTca1313AY.1160.003728
ORF1ab/nsp13368A368SGcaTca1212B.1.20.000106
ORF1ab/nsp13368A368SGcaTca1212M.21
ORF1ab/nsp13368A368SGcaTca1111B.1.2340.001451
ORF1ab/nsp13368A368SGcaTca99AY.200.00035
ORF1ab/nsp13368A368SGcaTca88P.10.000126
ORF1ab/nsp13368A368SGcaTca66AY.290.000095
ORF1ab/nsp13368A368SGcaTca66B.1.360.000875
ORF1ab/nsp13368A368SGcaTca66P.1.40.005859
ORF1ab/nsp13368A368SGcaTca55AY.9.20.000184
ORF1ab/nsp13368A368SGcaTca55AY.980.000395
ORF1ab/nsp13368A368SGcaTca55B.1.1600.000156
ORF1ab/nsp13368A368SGcaTca55B.400.001821
ORF1ab/nsp13368A368SGcaTca55C.350.00387
ORF1ab/nsp13368A368SGcaTca44AY.1210.000541
ORF1ab/nsp13368A368SGcaTca44AY.230.000279
ORF1ab/nsp13368A368SGcaTca44AY.260.000113
ORF1ab/nsp13368A368SGcaTca44AY.350.000932
ORF1ab/nsp13368A368SGcaTca44AY.60.000165
ORF1ab/nsp13368A368SGcaTca44AY.7.10.000451
ORF1ab/nsp13368A368SGcaTca44AY.75.10.000721
ORF1ab/nsp13368A368SGcaTca44AY.960.008299
ORF1ab/nsp13368A368SGcaTca44B.1.177.200.00607
ORF1ab/nsp13368A368SGcaTca44B.1.5130.055556
ORF1ab/nsp13368A368SGcaTca44P.1.100.001078
ORF1ab/nsp13368A368SGcaTca44P.1.70.001277
ORF1ab/nsp13368A368SGcaTca33AY.10.001187
ORF1ab/nsp13368A368SGcaTca33AY.1200.000112
ORF1ab/nsp13368A368SGcaTca33AY.16.10.00141
ORF1ab/nsp13368A368SGcaTca33AY.420.000121
ORF1ab/nsp13368A368SGcaTca33AY.450.000365
ORF1ab/nsp13368A368SGcaTca33AY.460.000312
ORF1ab/nsp13368A368SGcaTca33AY.530.000863
ORF1ab/nsp13368A368SGcaTca33AY.650.001599
ORF1ab/nsp13368A368SGcaTca33AY.780.004622
ORF1ab/nsp13368A368SGcaTca33B.1.1.2160.002671
ORF1ab/nsp13368A368SGcaTca33B.1.2210.000213
ORF1ab/nsp13368A368SGcaTca33B.1.3510.000089
ORF1ab/nsp13368A368SGcaTca33B.1.351.20.000908
ORF1ab/nsp13368A368SGcaTca33B.1.4660.069767
ORF1ab/nsp13368A368SGcaTca33B.1.466.20.001174
ORF1ab/nsp13368A368SGcaTca33B.1.6210.000266
ORF1ab/nsp13368A368SGcaTca22AY.30.00002
ORF1ab/nsp13368A368SGcaTca22AY.330.000134
ORF1ab/nsp13368A368SGcaTca22AY.46.20.001271
ORF1ab/nsp13368A368SGcaTca22AY.550.001835
ORF1ab/nsp13368A368SGcaTca22AY.720.002721
ORF1ab/nsp13368A368SGcaTca22AY.750.000112
ORF1ab/nsp13368A368SGcaTca22B.1.1.1890.003026
ORF1ab/nsp13368A368SGcaTca22B.1.1.2840.000215
ORF1ab/nsp13368A368SGcaTca22B.1.1.3170.000823
ORF1ab/nsp13368A368SGcaTca22B.1.177.540.001213
ORF1ab/nsp13368A368SGcaTca22B.1.2180.010309
ORF1ab/nsp13368A368SGcaTca22B.1.2240.05
ORF1ab/nsp13368A368SGcaTca22B.1.2580.000133
ORF1ab/nsp13368A368SGcaTca22B.1.4290.000047
ORF1ab/nsp13368A368SGcaTca22B.1.5640.000852
ORF1ab/nsp13368A368SGcaTca22B.1.5750.000607
ORF1ab/nsp13368A368SGcaTca22B.1.5770.001375
ORF1ab/nsp13368A368SGcaTca22B.1.6370.000146
ORF1ab/nsp13368A368SGcaTca22B.60.00182
ORF1ab/nsp13368A368SGcaTca22C.370.000232
ORF1ab/nsp13368A368SGcaTca22D.20.00015
ORF1ab/nsp13368A368SGcaTca11AW.10.003049
ORF1ab/nsp13368A368SGcaTca11AY.1050.000643
ORF1ab/nsp13368A368SGcaTca11AY.1100.000113
ORF1ab/nsp13368A368SGcaTca11AY.1130.000142
ORF1ab/nsp13368A368SGcaTca11AY.116.10.000311
ORF1ab/nsp13368A368SGcaTca11AY.1170.000085
ORF1ab/nsp13368A368SGcaTca11AY.120.20.001285
ORF1ab/nsp13368A368SGcaTca11AY.130.000161
ORF1ab/nsp13368A368SGcaTca11AY.190.00114
ORF1ab/nsp13368A368SGcaTca11AY.240.000431
ORF1ab/nsp13368A368SGcaTca11AY.320.000532
ORF1ab/nsp13368A368SGcaTca11AY.360.000148
ORF1ab/nsp13368A368SGcaTca11AY.4.2.10.000149
ORF1ab/nsp13368A368SGcaTca11AY.4.40.000409
ORF1ab/nsp13368A368SGcaTca11AY.4.50.000107
ORF1ab/nsp13368A368SGcaTca11AY.470.000031
ORF1ab/nsp13368A368SGcaTca11AY.5.30.000337
ORF1ab/nsp13368A368SGcaTca11AY.5.40.000277
ORF1ab/nsp13368A368SGcaTca11AY.600.000938
ORF1ab/nsp13368A368SGcaTca11AY.680.000274
ORF1ab/nsp13368A368SGcaTca11AY.700.000209
ORF1ab/nsp13368A368SGcaTca11AY.740.000116
ORF1ab/nsp13368A368SGcaTca11B.1.1.1550.071429
ORF1ab/nsp13368A368SGcaTca11B.1.1.2140.000055
ORF1ab/nsp13368A368SGcaTca11B.1.1.250.000569
ORF1ab/nsp13368A368SGcaTca11B.1.1.2610.008621
ORF1ab/nsp13368A368SGcaTca11B.1.1.2690.001353
ORF1ab/nsp13368A368SGcaTca11B.1.1.280.000311
ORF1ab/nsp13368A368SGcaTca11B.1.1.2940.001266
ORF1ab/nsp13368A368SGcaTca11B.1.1.3880.045455
ORF1ab/nsp13368A368SGcaTca11B.1.1.4530.008475
ORF1ab/nsp13368A368SGcaTca11B.1.1.4870.005587
ORF1ab/nsp13368A368SGcaTca11B.1.1.5190.00004
ORF1ab/nsp13368A368SGcaTca11B.1.177.160.000664
ORF1ab/nsp13368A368SGcaTca11B.1.177.600.000218
ORF1ab/nsp13368A368SGcaTca11B.1.177.860.000183
ORF1ab/nsp13368A368SGcaTca11B.1.2060.000816
ORF1ab/nsp13368A368SGcaTca11B.1.2140.003663
ORF1ab/nsp13368A368SGcaTca11B.1.2430.00007
ORF1ab/nsp13368A368SGcaTca11B.1.3690.000285
ORF1ab/nsp13368A368SGcaTca11B.1.3960.000706
ORF1ab/nsp13368A368SGcaTca11B.1.4270.00005
ORF1ab/nsp13368A368SGcaTca11B.1.4560.003268
ORF1ab/nsp13368A368SGcaTca11B.1.4680.005714
ORF1ab/nsp13368A368SGcaTca11B.1.5760.000907
ORF1ab/nsp13368A368SGcaTca11B.1.5950.000261
ORF1ab/nsp13368A368SGcaTca11B.1.6100.003546
ORF1ab/nsp13368A368SGcaTca11B.1.6180.004032
ORF1ab/nsp13368A368SGcaTca11B.1.619.10.000641
ORF1ab/nsp13368A368SGcaTca11B.1.80.001972
ORF1ab/nsp13368A368SGcaTca11B.610.005747
ORF1ab/nsp13368A368SGcaTca11P.1.10.000318
ORF1ab/nsp13368A368SGcaTca11P.1.140.000048
ORF1ab/nsp13368A368SGcaTca11P.1.170.000162
ORF1ab/nsp13368A368SGcaTca11P.60.003145
ORF1ab/nsp13368A368SGcaTca11Q.80.000165
ORF1ab/nsp13368A368SGcaTca11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.