CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : Mut = A336S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13336A336SA5660SnonsynGcaTca4242117242-17244

Details of the mutation A336S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13336A336SGcaTca4242All0.000008
ORF1ab/nsp13336A336SGcaTca88AY.1140.001849
ORF1ab/nsp13336A336SGcaTca88B.1.1.4810.571429
ORF1ab/nsp13336A336SGcaTca77AY.250.000042
ORF1ab/nsp13336A336SGcaTca55AY.40.000008
ORF1ab/nsp13336A336SGcaTca44AY.1020.000106
ORF1ab/nsp13336A336SGcaTca22B.1.20.000018
ORF1ab/nsp13336A336SGcaTca22P.10.000032
ORF1ab/nsp13336A336SGcaTca11AY.1030.000006
ORF1ab/nsp13336A336SGcaTca11AY.1130.000142
ORF1ab/nsp13336A336SGcaTca11AY.1190.000035
ORF1ab/nsp13336A336SGcaTca11B.1.1770.000013
ORF1ab/nsp13336A336SGcaTca11B.1.4740.001901
ORF1ab/nsp13336A336SGcaTca11B.1.5960.000087

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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