CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : Mut = A302S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13302A302SA5626SnonsynGctTct6796480.95434517140-17142
ORF1ab/nsp13302A302SA5626SnonsynGcTTcA679210.030927817140-17142
ORF1ab/nsp13302A302SA5626SnonsynGcTTcC67980.01178217140-17142
ORF1ab/nsp13302A302SA5626SnonsynGCTAGC67910.0014727517140-17142
ORF1ab/nsp13302A302SA5626SnonsynGcTTcG67910.0014727517140-17142

Details of the mutation A302S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13302A302SGctTct648679All0.000124
ORF1ab/nsp13302A302SGcTTcA21679All0.000004
ORF1ab/nsp13302A302SGcTTcC8679All0.000002
ORF1ab/nsp13302A302SGCTAGC1679All0
ORF1ab/nsp13302A302SGcTTcG1679All0
ORF1ab/nsp13302A302SGctTct134134B.1.1.2940.16962
ORF1ab/nsp13302A302SGctTct9090AY.250.000541
ORF1ab/nsp13302A302SGctTct4270B.1.1.70.000038
ORF1ab/nsp13302A302SGcTTcA1870B.1.1.70.000016
ORF1ab/nsp13302A302SGcTTcC870B.1.1.70.000007
ORF1ab/nsp13302A302SGCTAGC170B.1.1.70.000001
ORF1ab/nsp13302A302SGcTTcG170B.1.1.70.000001
ORF1ab/nsp13302A302SGctTct4343AY.40.000067
ORF1ab/nsp13302A302SGctTct3737B.10.000339
ORF1ab/nsp13302A302SGctTct3232B.1.10.000581
ORF1ab/nsp13302A302SGctTct2424B.1.617.20.00009
ORF1ab/nsp13302A302SGctTct2222AY.46.60.001589
ORF1ab/nsp13302A302SGctTct1616AY.1030.000099
ORF1ab/nsp13302A302SGctTct1515AY.430.000066
ORF1ab/nsp13302A302SGctTct1415B.1.20.000123
ORF1ab/nsp13302A302SGcTTcA115B.1.20.000009
ORF1ab/nsp13302A302SGctTct1212AY.1190.000424
ORF1ab/nsp13302A302SGctTct99B.1.1770.000119
ORF1ab/nsp13302A302SGctTct99B.1.2210.000639
ORF1ab/nsp13302A302SGctTct99C.30.10.060403
ORF1ab/nsp13302A302SGctTct99P.1.150.002091
ORF1ab/nsp13302A302SGctTct77B.1.2350.017632
ORF1ab/nsp13302A302SGctTct55B.1.1.1740.016892
ORF1ab/nsp13302A302SGctTct55B.1.1.3060.002192
ORF1ab/nsp13302A302SGctTct55B.1.1.540.015106
ORF1ab/nsp13302A302SGctTct55B.1.5260.000118
ORF1ab/nsp13302A302SGctTct44AY.1020.000106
ORF1ab/nsp13302A302SGctTct44AY.290.000063
ORF1ab/nsp13302A302SGctTct44AY.330.000267
ORF1ab/nsp13302A302SGctTct44AY.440.000024
ORF1ab/nsp13302A302SGctTct44AY.470.000124
ORF1ab/nsp13302A302SGctTct44B.1.1.280.001245
ORF1ab/nsp13302A302SGctTct44B.1.5090.003463
ORF1ab/nsp13302A302SGctTct44B.1.6370.000292
ORF1ab/nsp13302A302SGctTct44D.20.0003
ORF1ab/nsp13302A302SGctTct33AY.200.000117
ORF1ab/nsp13302A302SGctTct33AY.260.000085
ORF1ab/nsp13302A302SGctTct33AY.30.00003
ORF1ab/nsp13302A302SGctTct33AY.780.004622
ORF1ab/nsp13302A302SGctTct33B.1.4290.000071
ORF1ab/nsp13302A302SGctTct23P.10.000032
ORF1ab/nsp13302A302SGcTTcA13P.10.000016
ORF1ab/nsp13302A302SGcTTcA12A0.000387
ORF1ab/nsp13302A302SGctTct12A0.000387
ORF1ab/nsp13302A302SGctTct22AY.300.000791
ORF1ab/nsp13302A302SGctTct22AY.34.10.00102
ORF1ab/nsp13302A302SGctTct22AY.390.000049
ORF1ab/nsp13302A302SGctTct22AY.610.00021
ORF1ab/nsp13302A302SGctTct22AY.690.000373
ORF1ab/nsp13302A302SGctTct22B.1.2340.000264
ORF1ab/nsp13302A302SGctTct22B.1.617.30.00597
ORF1ab/nsp13302A302SGctTct11A.120.166667
ORF1ab/nsp13302A302SGctTct11A.2.5.20.001572
ORF1ab/nsp13302A302SGctTct11AD.20.000219
ORF1ab/nsp13302A302SGctTct11AY.1000.000046
ORF1ab/nsp13302A302SGctTct11AY.1160.000287
ORF1ab/nsp13302A302SGctTct11AY.410.000294
ORF1ab/nsp13302A302SGctTct11AY.420.00004
ORF1ab/nsp13302A302SGctTct11AY.450.000122
ORF1ab/nsp13302A302SGctTct11AY.490.003195
ORF1ab/nsp13302A302SGctTct11AY.5.30.000337
ORF1ab/nsp13302A302SGctTct11AY.520.000814
ORF1ab/nsp13302A302SGctTct11AY.540.000095
ORF1ab/nsp13302A302SGctTct11AY.7.10.000113
ORF1ab/nsp13302A302SGctTct11AY.740.000116
ORF1ab/nsp13302A302SGctTct11AY.750.000056
ORF1ab/nsp13302A302SGctTct11AY.830.001724
ORF1ab/nsp13302A302SGctTct11AY.880.000884
ORF1ab/nsp13302A302SGctTct11AY.990.001049
ORF1ab/nsp13302A302SGctTct11B.1.1.330.000421
ORF1ab/nsp13302A302SGctTct11B.1.1.370.000193
ORF1ab/nsp13302A302SGctTct11B.1.1.5190.00004
ORF1ab/nsp13302A302SGctTct11B.1.1600.000031
ORF1ab/nsp13302A302SGctTct11B.1.2410.000812
ORF1ab/nsp13302A302SGctTct11B.1.3510.00003
ORF1ab/nsp13302A302SGctTct11B.1.36.240.006173
ORF1ab/nsp13302A302SGctTct11B.1.3620.001541
ORF1ab/nsp13302A302SGctTct11B.1.3690.000285
ORF1ab/nsp13302A302SGctTct11B.1.4270.00005
ORF1ab/nsp13302A302SGctTct11B.1.517.10.005263
ORF1ab/nsp13302A302SGctTct11B.1.5820.000491
ORF1ab/nsp13302A302SGctTct11B.1.5950.000261
ORF1ab/nsp13302A302SGctTct11B.1.6090.000479
ORF1ab/nsp13302A302SGctTct11B.1.700.02439
ORF1ab/nsp13302A302SGctTct11B.4.80.071429
ORF1ab/nsp13302A302SGctTct11C.10.002392
ORF1ab/nsp13302A302SGctTct11N.90.005952

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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