CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : Mut = A208V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13208A208VA5532VnonsyngCtgTt160916070.99875716858-16860
ORF1ab/nsp13208A208VA5532VnonsyngCTgTC160920.0012430116858-16860

Details of the mutation A208V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13208A208VgCtgTt16071609All0.000307
ORF1ab/nsp13208A208VgCTgTC21609All0
ORF1ab/nsp13208A208VgCtgTt346346B.1.6210.030628
ORF1ab/nsp13208A208VgCtgTt124124B.1.1.70.000111
ORF1ab/nsp13208A208VgCtgTt9393AY.40.000145
ORF1ab/nsp13208A208VgCtgTt8888AY.180.888889
ORF1ab/nsp13208A208VgCtgTt8888AY.30.000875
ORF1ab/nsp13208A208VgCtgTt7676AY.1030.000472
ORF1ab/nsp13208A208VgCtgTt7676B.1.617.20.000286
ORF1ab/nsp13208A208VgCtgTt6666AY.440.000402
ORF1ab/nsp13208A208VgCtgTt5959B.1.20.00052
ORF1ab/nsp13208A208VgCtgTt5555B.10.000504
ORF1ab/nsp13208A208VgCtgTt3131B.1.1.5190.001231
ORF1ab/nsp13208A208VgCtgTt2929B.1.10.000526
ORF1ab/nsp13208A208VgCtgTt2727B.1.5850.75
ORF1ab/nsp13208A208VgCtgTt2626AY.430.000115
ORF1ab/nsp13208A208VgCtgTt2525B.1.4270.001262
ORF1ab/nsp13208A208VgCtgTt2323AY.250.000138
ORF1ab/nsp13208A208VgCtgTt2020B.1.5260.00047
ORF1ab/nsp13208A208VgCtgTt1818AY.1020.000477
ORF1ab/nsp13208A208VgCtgTt1616AY.700.003336
ORF1ab/nsp13208A208VgCtgTt1414AY.390.000346
ORF1ab/nsp13208A208VgCtgTt1212B.1.1770.000158
ORF1ab/nsp13208A208VgCtgTt1212B.1.596.10.11215
ORF1ab/nsp13208A208VgCtgTt1111AY.1200.000409
ORF1ab/nsp13208A208VgCtgTt1111AY.7.10.00124
ORF1ab/nsp13208A208VgCtgTt1111B.1.4000.004719
ORF1ab/nsp13208A208VgCtgTt88AY.160.003037
ORF1ab/nsp13208A208VgCtgTt88B.1.3510.000238
ORF1ab/nsp13208A208VgCtgTt88B.1.4290.000188
ORF1ab/nsp13208A208VgCtgTt88C.36.30.004538
ORF1ab/nsp13208A208VgCtgTt77AY.1130.000997
ORF1ab/nsp13208A208VgCtgTt77AY.46.40.001152
ORF1ab/nsp13208A208VgCtgTt77AY.50.000145
ORF1ab/nsp13208A208VgCtgTt77AY.930.001912
ORF1ab/nsp13208A208VgCtgTt77R.10.00063
ORF1ab/nsp13208A208VgCtgTt66AY.290.000095
ORF1ab/nsp13208A208VgCtgTt66P.1.140.000287
ORF1ab/nsp13208A208VgCtgTt55AY.750.00028
ORF1ab/nsp13208A208VgCtgTt55B.1.36.290.002587
ORF1ab/nsp13208A208VgCtgTt55D.20.000375
ORF1ab/nsp13208A208VgCtgTt44AY.1160.001147
ORF1ab/nsp13208A208VgCtgTt44AY.200.000155
ORF1ab/nsp13208A208VgCtgTt44AY.450.000487
ORF1ab/nsp13208A208VgCtgTt44B.1.177.210.000306
ORF1ab/nsp13208A208VgCtgTt44B.1.2430.000278
ORF1ab/nsp13208A208VgCtgTt44B.1.5950.001044
ORF1ab/nsp13208A208VgCtgTt33AY.1180.000188
ORF1ab/nsp13208A208VgCtgTt33AY.1190.000106
ORF1ab/nsp13208A208VgCtgTt33AY.1210.000406
ORF1ab/nsp13208A208VgCtgTt33AY.16.10.00141
ORF1ab/nsp13208A208VgCtgTt33AY.29.10.000662
ORF1ab/nsp13208A208VgCtgTt33B.1.1.2220.000612
ORF1ab/nsp13208A208VgCtgTt33B.1.1.3050.011583
ORF1ab/nsp13208A208VgCtgTt33B.1.1.370.000579
ORF1ab/nsp13208A208VgCtgTt33C.1.20.012766
ORF1ab/nsp13208A208VgCtgTt33P.10.000047
ORF1ab/nsp13208A208VgCtgTt33Q.40.001364
ORF1ab/nsp13208A208VgCtgTt120.055556
ORF1ab/nsp13208A208VgCTgTC120.055556
ORF1ab/nsp13208A208VgCtgTt22AY.1000.000092
ORF1ab/nsp13208A208VgCtgTt22AY.300.000791
ORF1ab/nsp13208A208VgCtgTt22AY.320.001065
ORF1ab/nsp13208A208VgCtgTt22AY.39.10.000079
ORF1ab/nsp13208A208VgCtgTt22AY.4.20.000043
ORF1ab/nsp13208A208VgCtgTt22AY.420.00008
ORF1ab/nsp13208A208VgCtgTt22AY.46.60.000144
ORF1ab/nsp13208A208VgCtgTt22AY.470.000062
ORF1ab/nsp13208A208VgCtgTt22AY.740.000231
ORF1ab/nsp13208A208VgCtgTt22AY.9.10.000167
ORF1ab/nsp13208A208VgCtgTt22B0.000256
ORF1ab/nsp13208A208VgCtgTt22B.1.1.3180.000604
ORF1ab/nsp13208A208VgCtgTt22B.1.1.330.000842
ORF1ab/nsp13208A208VgCtgTt22B.1.1.630.000772
ORF1ab/nsp13208A208VgCtgTt22B.1.2340.000264
ORF1ab/nsp13208A208VgCtgTt22B.1.2580.000133
ORF1ab/nsp13208A208VgCtgTt22B.1.258.170.000208
ORF1ab/nsp13208A208VgCtgTt22B.1.2980.004228
ORF1ab/nsp13208A208VgCtgTt22B.1.4460.04
ORF1ab/nsp13208A208VgCTgTC12B.1.4700.001404
ORF1ab/nsp13208A208VgCtgTt12B.1.4700.001404
ORF1ab/nsp13208A208VgCtgTt22B.1.5960.000174
ORF1ab/nsp13208A208VgCtgTt22B.1.617.10.000258
ORF1ab/nsp13208A208VgCtgTt22C.36.3.10.005435
ORF1ab/nsp13208A208VgCtgTt11A.10.000282
ORF1ab/nsp13208A208VgCtgTt11A.2.5.20.001572
ORF1ab/nsp13208A208VgCtgTt11AY.100.00053
ORF1ab/nsp13208A208VgCtgTt11AY.1050.000643
ORF1ab/nsp13208A208VgCtgTt11AY.1070.000466
ORF1ab/nsp13208A208VgCtgTt11AY.116.10.000311
ORF1ab/nsp13208A208VgCtgTt11AY.120.2.10.000498
ORF1ab/nsp13208A208VgCtgTt11AY.130.000161
ORF1ab/nsp13208A208VgCtgTt11AY.230.00007
ORF1ab/nsp13208A208VgCtgTt11AY.360.000148
ORF1ab/nsp13208A208VgCtgTt11AY.4.2.10.000149
ORF1ab/nsp13208A208VgCtgTt11AY.490.003195
ORF1ab/nsp13208A208VgCtgTt11AY.540.000095
ORF1ab/nsp13208A208VgCtgTt11AY.60.000041
ORF1ab/nsp13208A208VgCtgTt11AY.620.000436
ORF1ab/nsp13208A208VgCtgTt11AY.650.000533
ORF1ab/nsp13208A208VgCtgTt11AY.670.000464
ORF1ab/nsp13208A208VgCtgTt11AY.690.000187
ORF1ab/nsp13208A208VgCtgTt11AY.710.000475
ORF1ab/nsp13208A208VgCtgTt11AY.920.000287
ORF1ab/nsp13208A208VgCtgTt11AY.980.000079
ORF1ab/nsp13208A208VgCtgTt11AY.99.20.000092
ORF1ab/nsp13208A208VgCtgTt11B.1.1.2420.043478
ORF1ab/nsp13208A208VgCtgTt11B.1.1.2580.003257
ORF1ab/nsp13208A208VgCtgTt11B.1.1.3060.000438
ORF1ab/nsp13208A208VgCtgTt11B.1.1.3480.000796
ORF1ab/nsp13208A208VgCtgTt11B.1.1.4340.000349
ORF1ab/nsp13208A208VgCtgTt11B.1.1.4480.002033
ORF1ab/nsp13208A208VgCtgTt11B.1.1600.000031
ORF1ab/nsp13208A208VgCtgTt11B.1.177.120.000152
ORF1ab/nsp13208A208VgCtgTt11B.1.177.170.000821
ORF1ab/nsp13208A208VgCtgTt11B.1.177.570.000281
ORF1ab/nsp13208A208VgCtgTt11B.1.177.60.000977
ORF1ab/nsp13208A208VgCtgTt11B.1.177.810.000189
ORF1ab/nsp13208A208VgCtgTt11B.1.2060.000816
ORF1ab/nsp13208A208VgCtgTt11B.1.2210.000071
ORF1ab/nsp13208A208VgCtgTt11B.1.3110.000275
ORF1ab/nsp13208A208VgCtgTt11B.1.3200.001245
ORF1ab/nsp13208A208VgCtgTt11B.1.351.50.0006
ORF1ab/nsp13208A208VgCtgTt11B.1.36.170.000494
ORF1ab/nsp13208A208VgCtgTt11B.1.4280.00102
ORF1ab/nsp13208A208VgCtgTt11B.1.4390.005917
ORF1ab/nsp13208A208VgCtgTt11B.1.4620.007246
ORF1ab/nsp13208A208VgCtgTt11B.1.5650.00081
ORF1ab/nsp13208A208VgCtgTt11B.1.5770.000687
ORF1ab/nsp13208A208VgCtgTt11B.1.6060.006024
ORF1ab/nsp13208A208VgCtgTt11B.1.6230.000536
ORF1ab/nsp13208A208VgCtgTt11B.1.690.035714
ORF1ab/nsp13208A208VgCtgTt11B.40.002208
ORF1ab/nsp13208A208VgCtgTt11C.230.005814
ORF1ab/nsp13208A208VgCtgTt11C.370.000116
ORF1ab/nsp13208A208VgCtgTt11P.1.90.004808
ORF1ab/nsp13208A208VgCtgTt11P.20.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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