CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : CodonNum = 81

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp1381F81FF5405FsynttTttC923923116477-16479
ORF1ab/nsp1381F81delF5405deldelTTT---5454116477-16479
ORF1ab/nsp1381F81LF5405LnonsynTttCtt35270.77142916477-16479
ORF1ab/nsp1381F81LF5405LnonsynttTttG3550.14285716477-16479
ORF1ab/nsp1381F81LF5405LnonsynttTttA3530.085714316477-16479
ORF1ab/nsp1381F81SF5405SnonsyntTttCt17120.70588216477-16479
ORF1ab/nsp1381F81SF5405SnonsyntTTtCA1750.29411816477-16479
ORF1ab/nsp1381F81VF5405VnonsynTttGtt1515116477-16479
ORF1ab/nsp1381F81YF5405YnonsyntTttAt430.7516477-16479
ORF1ab/nsp1381F81YF5405YnonsyntTTtAC410.2516477-16479
ORF1ab/nsp1381F81CF5405CnonsyntTttGt22116477-16479
ORF1ab/nsp1381F81IF5405InonsynTttAtt22116477-16479
ORF1ab/nsp1381F81del2F5405del2deltTTt--11116477-16479
ORF1ab/nsp1381F81del1F5405del1delttTtt-11116477-16479

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp1381F81FttTttC923923All0.000177
ORF1ab/nsp1381F81FttTttC549549B.1.1.2320.99637
ORF1ab/nsp1381F81FttTttC7979AK.11
ORF1ab/nsp1381F81delTTT---5454All0.00001
ORF1ab/nsp1381F81FttTttC4545B.1.617.20.000169
ORF1ab/nsp1381F81LTttCtt2735All0.000005
ORF1ab/nsp1381F81LttTttG535All0.000001
ORF1ab/nsp1381F81LttTttA335All0.000001
ORF1ab/nsp1381F81FttTttC3434P.10.000536
ORF1ab/nsp1381F81delTTT---2929B.1.1.70.000026
ORF1ab/nsp1381F81FttTttC2929B.1.258.110.011494
ORF1ab/nsp1381F81FttTttC2626B.1.1.70.000023
ORF1ab/nsp1381F81FttTttC2222AK.21
ORF1ab/nsp1381F81StTttCt1217All0.000002
ORF1ab/nsp1381F81StTTtCA517All0.000001
ORF1ab/nsp1381F81FttTttC1616B.1.20.000141
ORF1ab/nsp1381F81VTttGtt1515All0.000003
ORF1ab/nsp1381F81FttTttC1111AY.120.10.003531
ORF1ab/nsp1381F81FttTttC1111B.10.000101
ORF1ab/nsp1381F81FttTttC99AY.430.00004
ORF1ab/nsp1381F81FttTttC99AY.440.000055
ORF1ab/nsp1381F81StTttCt68B.10.000055
ORF1ab/nsp1381F81StTTtCA28B.10.000018
ORF1ab/nsp1381F81LTttCtt48B.1.1.70.000004
ORF1ab/nsp1381F81LttTttG48B.1.1.70.000004
ORF1ab/nsp1381F81FttTttC88P.1.140.000382
ORF1ab/nsp1381F81FttTttC88P.1.70.002554
ORF1ab/nsp1381F81FttTttC77AY.40.000011
ORF1ab/nsp1381F81FttTttC77AY.46.50.001389
ORF1ab/nsp1381F81FttTttC66AY.30.00006
ORF1ab/nsp1381F81FttTttC66B.1.10.000109
ORF1ab/nsp1381F81VTttGtt66B.1.1.70.000005
ORF1ab/nsp1381F81FttTttC66B.1.177.240.007772
ORF1ab/nsp1381F81VTttGtt66B.1.5250.000679
ORF1ab/nsp1381F81FttTttC55AY.200.000194
ORF1ab/nsp1381F81LTttCtt55AY.40.000008
ORF1ab/nsp1381F81LTttCtt55AY.440.00003
ORF1ab/nsp1381F81LTttCtt55B.1.1770.000066
ORF1ab/nsp1381F81FttTttC55B.1.5260.000118
ORF1ab/nsp1381F81YtTttAt34All0.000001
ORF1ab/nsp1381F81YtTTtAC14All0
ORF1ab/nsp1381F81FttTttC44AY.1100.000451
ORF1ab/nsp1381F81delTTT---33B.1.1770.00004
ORF1ab/nsp1381F81FttTttC33B.1.4270.000151
ORF1ab/nsp1381F81delTTT---33B.1.617.20.000011
ORF1ab/nsp1381F81YtTttAt220.111111
ORF1ab/nsp1381F81delTTT---220.111111
ORF1ab/nsp1381F81CtTttGt22All0
ORF1ab/nsp1381F81ITttAtt22All0
ORF1ab/nsp1381F81LTttCtt22AY.20.000712
ORF1ab/nsp1381F81FttTttC22AY.260.000057
ORF1ab/nsp1381F81delTTT---22AY.430.000009
ORF1ab/nsp1381F81VTttGtt22B.10.000018
ORF1ab/nsp1381F81LTttCtt22B.10.000018
ORF1ab/nsp1381F81delTTT---22B.1.10.000036
ORF1ab/nsp1381F81FttTttC22B.1.1.1890.003026
ORF1ab/nsp1381F81FttTttC22B.1.1.280.000622
ORF1ab/nsp1381F81ITttAtt22B.1.20.000018
ORF1ab/nsp1381F81FttTttC22B.1.2130.029851
ORF1ab/nsp1381F81LttTttA22B.1.2210.000142
ORF1ab/nsp1381F81VTttGtt110.055556
ORF1ab/nsp1381F81LttTttA110.055556
ORF1ab/nsp1381F81del1ttTtt-11A.10.000282
ORF1ab/nsp1381F81LTttCtt11A.20.000662
ORF1ab/nsp1381F81del1ttTtt-11All0
ORF1ab/nsp1381F81del2tTTt--11All0
ORF1ab/nsp1381F81delTTT---11AY.1110.000183
ORF1ab/nsp1381F81FttTttC11AY.1170.000085
ORF1ab/nsp1381F81FttTttC11AY.250.000006
ORF1ab/nsp1381F81FttTttC11AY.290.000016
ORF1ab/nsp1381F81LTttCtt11AY.330.000067
ORF1ab/nsp1381F81delTTT---11AY.40.000002
ORF1ab/nsp1381F81delTTT---11AY.4.50.000107
ORF1ab/nsp1381F81StTttCt11AY.440.000006
ORF1ab/nsp1381F81LTttCtt11AY.90.000068
ORF1ab/nsp1381F81FttTttC11B0.000128
ORF1ab/nsp1381F81YtTTtAC11B0.000128
ORF1ab/nsp1381F81CtTttGt11B.10.000009
ORF1ab/nsp1381F81StTttCt11B.1.10.000018
ORF1ab/nsp1381F81FttTttC11B.1.1.100.001115
ORF1ab/nsp1381F81StTttCt11B.1.1.1760.000439
ORF1ab/nsp1381F81StTTtCA11B.1.1.2320.001815
ORF1ab/nsp1381F81delTTT---11B.1.1.2320.001815
ORF1ab/nsp1381F81StTttCt11B.1.1.2820.011628
ORF1ab/nsp1381F81delTTT---11B.1.1.3120.001912
ORF1ab/nsp1381F81StTTtCA11B.1.1.3150.008475
ORF1ab/nsp1381F81StTttCt11B.1.1.3260.001761
ORF1ab/nsp1381F81CtTttGt11B.1.1.70.000001
ORF1ab/nsp1381F81del2tTTt--11B.1.1.70.000001
ORF1ab/nsp1381F81StTTtCA11B.1.1.70.000001
ORF1ab/nsp1381F81YtTttAt11B.1.1.70.000001
ORF1ab/nsp1381F81delTTT---11B.1.1600.000031
ORF1ab/nsp1381F81LTttCtt11B.1.177.120.000152
ORF1ab/nsp1381F81delTTT---11B.1.177.40.000211
ORF1ab/nsp1381F81delTTT---11B.1.177.730.000566
ORF1ab/nsp1381F81LttTttG11B.1.177.760.002494
ORF1ab/nsp1381F81delTTT---11B.1.177.830.001481
ORF1ab/nsp1381F81StTttCt11B.1.2060.000816
ORF1ab/nsp1381F81FttTttC11B.1.2580.000067
ORF1ab/nsp1381F81delTTT---11B.1.2580.000067
ORF1ab/nsp1381F81delTTT---11B.1.416.10.001563
ORF1ab/nsp1381F81FttTttC11B.1.4380.006536
ORF1ab/nsp1381F81delTTT---11B.1.617.30.002985
ORF1ab/nsp1381F81FttTttC11B.1.6270.00202
ORF1ab/nsp1381F81FttTttC11B.1.6280.000352
ORF1ab/nsp1381F81FttTttC11D.20.000075
ORF1ab/nsp1381F81delTTT---11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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