CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : CodonNum = 584

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13584K584NK5908NnonsynaaGaaT8468450.99881817986-17988
ORF1ab/nsp13584K584NK5908NnonsynaaGaaC84610.0011820317986-17988
ORF1ab/nsp13584K584KK5908KsynaaGaaA220220117986-17988
ORF1ab/nsp13584K584EK5908EnonsynAagGag202202117986-17988
ORF1ab/nsp13584K584RK5908RnonsynaAgaGg1181170.99152517986-17988
ORF1ab/nsp13584K584RK5908RnonsynAAGCGA11810.0084745817986-17988
ORF1ab/nsp13584K584delK5908deldelAAG---2020117986-17988
ORF1ab/nsp13584K584TK5908TnonsynaAgaCg99117986-17988
ORF1ab/nsp13584K584QK5908QnonsynAagCag88117986-17988
ORF1ab/nsp13584K584MK5908MnonsynaAgaTg22117986-17988
ORF1ab/nsp13584K584DK5908DnonsynAaGGaC11117986-17988

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13584K584NaaGaaT845846All0.000162
ORF1ab/nsp13584K584NaaGaaC1846All0
ORF1ab/nsp13584K584NaaGaaT314314B.1.3510.009334
ORF1ab/nsp13584K584NaaGaaT234234AY.40.000364
ORF1ab/nsp13584K584KaaGaaA220220All0.000042
ORF1ab/nsp13584K584EAagGag202202All0.000039
ORF1ab/nsp13584K584RaAgaGg117118All0.000022
ORF1ab/nsp13584K584RAAGCGA1118All0
ORF1ab/nsp13584K584NaaGaaT6262B.1.428.30.794872
ORF1ab/nsp13584K584EAagGag4747AY.200.001827
ORF1ab/nsp13584K584NaaGaaT4545B.1.1.70.00004
ORF1ab/nsp13584K584NaaGaaT4444AY.680.012045
ORF1ab/nsp13584K584KaaGaaA4040C.36.30.022689
ORF1ab/nsp13584K584EAagGag3636B.1.1.70.000032
ORF1ab/nsp13584K584RaAgaGg3636B.1.617.10.004643
ORF1ab/nsp13584K584EAagGag2828B.1.177.600.006116
ORF1ab/nsp13584K584RaAgaGg2727B.1.177.860.004953
ORF1ab/nsp13584K584delAAG---2020All0.000004
ORF1ab/nsp13584K584KaaGaaA2020B.1.3980.059524
ORF1ab/nsp13584K584KaaGaaA1717AY.40.000026
ORF1ab/nsp13584K584RaAgaGg1717B.1.1.70.000015
ORF1ab/nsp13584K584KaaGaaA1616B.1.1.70.000014
ORF1ab/nsp13584K584EAagGag1414B.1.617.20.000053
ORF1ab/nsp13584K584NaaGaaT1313AY.30.000129
ORF1ab/nsp13584K584EAagGag1313AY.40.00002
ORF1ab/nsp13584K584EAagGag1313AY.430.000058
ORF1ab/nsp13584K584EAagGag1313B.1.1.3740.030879
ORF1ab/nsp13584K584NaaGaaT1212AY.430.000053
ORF1ab/nsp13584K584KaaGaaA1212AY.430.000053
ORF1ab/nsp13584K584EAagGag1111B.1.10.0002
ORF1ab/nsp13584K584RaAgaGg1111B.1.1.4040.174603
ORF1ab/nsp13584K584NaaGaaT1111B.1.5950.002871
ORF1ab/nsp13584K584NaaGaaT1111B.1.617.20.000041
ORF1ab/nsp13584K584NaaGaaT1111B.1.6210.000974
ORF1ab/nsp13584K584NaaGaaT1010B.10.000092
ORF1ab/nsp13584K584KaaGaaA1010B.1.360.001459
ORF1ab/nsp13584K584TaAgaCg99All0.000002
ORF1ab/nsp13584K584KaaGaaA99B.10.000082
ORF1ab/nsp13584K584delAAG---99B.1.1.70.000008
ORF1ab/nsp13584K584NaaGaaT99P.10.000142
ORF1ab/nsp13584K584QAagCag88All0.000002
ORF1ab/nsp13584K584NaaGaaT88B.1.10.000145
ORF1ab/nsp13584K584KaaGaaA88B.1.1770.000105
ORF1ab/nsp13584K584KaaGaaA88C.360.007286
ORF1ab/nsp13584K584KaaGaaA77AY.1160.002007
ORF1ab/nsp13584K584NaaGaaT77B.1.20.000062
ORF1ab/nsp13584K584EAagGag66AY.440.000037
ORF1ab/nsp13584K584TaAgaCg66B.1.1.70.000005
ORF1ab/nsp13584K584KaaGaaA66B.1.4290.000141
ORF1ab/nsp13584K584KaaGaaA66P.10.000095
ORF1ab/nsp13584K584KaaGaaA44AY.1000.000184
ORF1ab/nsp13584K584RaAgaGg44AY.250.000024
ORF1ab/nsp13584K584NaaGaaT44AY.260.000113
ORF1ab/nsp13584K584NaaGaaT44AY.360.000593
ORF1ab/nsp13584K584KaaGaaA44B.1.1600.000125
ORF1ab/nsp13584K584QAagCag44B.1.617.20.000015
ORF1ab/nsp13584K584KaaGaaA33AY.230.000209
ORF1ab/nsp13584K584EAagGag33AY.250.000018
ORF1ab/nsp13584K584NaaGaaT33AY.440.000018
ORF1ab/nsp13584K584KaaGaaA33AY.60.000123
ORF1ab/nsp13584K584NaaGaaT33B.1.1.120.022388
ORF1ab/nsp13584K584NaaGaaT33B.1.160.70.006237
ORF1ab/nsp13584K584KaaGaaA33B.1.20.000026
ORF1ab/nsp13584K584EAagGag33B.1.2580.0002
ORF1ab/nsp13584K584KaaGaaA33B.1.5260.000071
ORF1ab/nsp13584K584KaaGaaA33B.1.617.20.000011
ORF1ab/nsp13584K584RaAgaGg33B.1.617.20.000011
ORF1ab/nsp13584K584KaaGaaA33B.1.6370.000219
ORF1ab/nsp13584K584NaaGaaT33B.60.00273
ORF1ab/nsp13584K584KaaGaaA33P.1.120.001452
ORF1ab/nsp13584K584MaAgaTg22All0
ORF1ab/nsp13584K584EAagGag22AY.1180.000125
ORF1ab/nsp13584K584NaaGaaT22AY.1210.000271
ORF1ab/nsp13584K584KaaGaaA22AY.250.000012
ORF1ab/nsp13584K584NaaGaaT22AY.250.000012
ORF1ab/nsp13584K584KaaGaaA22AY.290.000032
ORF1ab/nsp13584K584NaaGaaT22AY.290.000032
ORF1ab/nsp13584K584RaAgaGg22AY.330.000134
ORF1ab/nsp13584K584RaAgaGg22AY.40.000003
ORF1ab/nsp13584K584NaaGaaT22AY.4.20.000043
ORF1ab/nsp13584K584NaaGaaT22AY.4.50.000215
ORF1ab/nsp13584K584KaaGaaA22AY.440.000012
ORF1ab/nsp13584K584EAagGag22AY.610.00021
ORF1ab/nsp13584K584KaaGaaA22B.1.10.000036
ORF1ab/nsp13584K584RaAgaGg22B.1.1.1530.002191
ORF1ab/nsp13584K584TaAgaCg22B.1.1.2140.000111
ORF1ab/nsp13584K584RaAgaGg22B.1.1.500.001358
ORF1ab/nsp13584K584NaaGaaT22B.1.1770.000026
ORF1ab/nsp13584K584NaaGaaT22B.1.177.570.000562
ORF1ab/nsp13584K584KaaGaaA22B.1.177.580.002663
ORF1ab/nsp13584K584EAagGag22B.1.20.000018
ORF1ab/nsp13584K584NaaGaaT22B.1.3460.002621
ORF1ab/nsp13584K584EAagGag22B.1.4360.002058
ORF1ab/nsp13584K584KaaGaaA22P.1.70.000639
ORF1ab/nsp13584K584DAaGGaC110.055556
ORF1ab/nsp13584K584NaaGaaC110.055556
ORF1ab/nsp13584K584EAagGag110.055556
ORF1ab/nsp13584K584KaaGaaA110.055556
ORF1ab/nsp13584K584KaaGaaA11A.2.40.003367
ORF1ab/nsp13584K584DAaGGaC11All0
ORF1ab/nsp13584K584NaaGaaT11AY.1000.000046
ORF1ab/nsp13584K584RaAgaGg11AY.1110.000183
ORF1ab/nsp13584K584KaaGaaA11AY.1180.000063
ORF1ab/nsp13584K584NaaGaaT11AY.1190.000035
ORF1ab/nsp13584K584NaaGaaT11AY.1200.000037
ORF1ab/nsp13584K584RaAgaGg11AY.1210.000135
ORF1ab/nsp13584K584RaAgaGg11AY.16.10.00047
ORF1ab/nsp13584K584NaaGaaT11AY.240.000431
ORF1ab/nsp13584K584QAagCag11AY.250.000006
ORF1ab/nsp13584K584delAAG---11AY.250.000006
ORF1ab/nsp13584K584QAagCag11AY.280.00189
ORF1ab/nsp13584K584KaaGaaA11AY.30.00001
ORF1ab/nsp13584K584QAagCag11AY.330.000067
ORF1ab/nsp13584K584KaaGaaA11AY.340.000097
ORF1ab/nsp13584K584NaaGaaT11AY.370.000316
ORF1ab/nsp13584K584RaAgaGg11AY.390.000025
ORF1ab/nsp13584K584NaaGaaT11AY.390.000025
ORF1ab/nsp13584K584NaaGaaT11AY.39.10.00004
ORF1ab/nsp13584K584RaAgaGg11AY.39.10.00004
ORF1ab/nsp13584K584delAAG---11AY.40.000002
ORF1ab/nsp13584K584EAagGag11AY.420.00004
ORF1ab/nsp13584K584delAAG---11AY.430.000004
ORF1ab/nsp13584K584EAagGag11AY.450.000122
ORF1ab/nsp13584K584delAAG---11AY.46.20.000635
ORF1ab/nsp13584K584KaaGaaA11AY.470.000031
ORF1ab/nsp13584K584NaaGaaT11AY.50.000021
ORF1ab/nsp13584K584NaaGaaT11AY.540.000095
ORF1ab/nsp13584K584KaaGaaA11AY.610.000105
ORF1ab/nsp13584K584NaaGaaT11AY.610.000105
ORF1ab/nsp13584K584KaaGaaA11AY.690.000187
ORF1ab/nsp13584K584NaaGaaT11AY.740.000116
ORF1ab/nsp13584K584delAAG---11AY.750.000056
ORF1ab/nsp13584K584RaAgaGg11AY.750.000056
ORF1ab/nsp13584K584NaaGaaT11AY.9.20.000037
ORF1ab/nsp13584K584QAagCag11AY.920.000287
ORF1ab/nsp13584K584NaaGaaT11AY.970.001701
ORF1ab/nsp13584K584MaAgaTg11AY.980.000079
ORF1ab/nsp13584K584KaaGaaA11AY.98.10.000048
ORF1ab/nsp13584K584delAAG---11AY.99.10.001553
ORF1ab/nsp13584K584RaAgaGg11B.10.000009
ORF1ab/nsp13584K584delAAG---11B.10.000009
ORF1ab/nsp13584K584RaAgaGg11B.1.10.000018
ORF1ab/nsp13584K584TaAgaCg11B.1.1.3060.000438
ORF1ab/nsp13584K584KaaGaaA11B.1.1.3150.008475
ORF1ab/nsp13584K584NaaGaaT11B.1.1600.000031
ORF1ab/nsp13584K584delAAG---11B.1.160.70.002079
ORF1ab/nsp13584K584KaaGaaA11B.1.177.120.000152
ORF1ab/nsp13584K584delAAG---11B.1.177.830.001481
ORF1ab/nsp13584K584KaaGaaA11B.1.2210.000071
ORF1ab/nsp13584K584KaaGaaA11B.1.2320.000537
ORF1ab/nsp13584K584MaAgaTg11B.1.2340.000132
ORF1ab/nsp13584K584KaaGaaA11B.1.258.170.000104
ORF1ab/nsp13584K584RaAgaGg11B.1.3110.000275
ORF1ab/nsp13584K584EAagGag11B.1.3510.00003
ORF1ab/nsp13584K584KaaGaaA11B.1.36.350.002604
ORF1ab/nsp13584K584KaaGaaA11B.1.3970.004854
ORF1ab/nsp13584K584EAagGag11B.1.3970.004854
ORF1ab/nsp13584K584KaaGaaA11B.1.3990.001934
ORF1ab/nsp13584K584NaaGaaT11B.1.4290.000024
ORF1ab/nsp13584K584RaAgaGg11B.1.4290.000024
ORF1ab/nsp13584K584KaaGaaA11B.1.4380.006536
ORF1ab/nsp13584K584RaAgaGg11B.1.4740.001901
ORF1ab/nsp13584K584NaaGaaT11B.1.5880.00091
ORF1ab/nsp13584K584KaaGaaA11B.1.5960.000087
ORF1ab/nsp13584K584EAagGag11B.1.6090.000479
ORF1ab/nsp13584K584RAAGCGA11B.1.617.30.002985
ORF1ab/nsp13584K584delAAG---11C.170.055556
ORF1ab/nsp13584K584EAagGag11P.10.000016
ORF1ab/nsp13584K584NaaGaaT11P.1.10.10.00813
ORF1ab/nsp13584K584KaaGaaA11P.1.140.000048
ORF1ab/nsp13584K584NaaGaaT11Q.20.000613
ORF1ab/nsp13584K584delAAG---11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.