CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : CodonNum = 468 & Codon = tTa

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13468S468LS5792LnonsyntCatTa367736750.99945617638-17640

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13468S468LtCatTa36753677All0.000703
ORF1ab/nsp13468S468LtCatTa11671167B.1.2060.951876
ORF1ab/nsp13468S468LtCatTa743743B.1.5760.673617
ORF1ab/nsp13468S468LtCatTa462462B.1.20.004068
ORF1ab/nsp13468S468LtCatTa359359B.10.003288
ORF1ab/nsp13468S468LtCatTa239239B.1.5460.885185
ORF1ab/nsp13468S468LtCatTa124124B.1.1.70.000111
ORF1ab/nsp13468S468LtCatTa7777B.1.3631
ORF1ab/nsp13468S468LtCatTa5151P.1.140.002438
ORF1ab/nsp13468S468LtCatTa4040B.1.10.000726
ORF1ab/nsp13468S468LtCatTa4040B.1.6090.019175
ORF1ab/nsp13468S468LtCatTa2626B.1.5960.002266
ORF1ab/nsp13468S468LtCatTa1818B.1.5950.004697
ORF1ab/nsp13468S468LtCatTa1515B.1.4090.011719
ORF1ab/nsp13468S468LtCatTa1414AY.40.000022
ORF1ab/nsp13468S468LtCatTa1414B.1.1770.000184
ORF1ab/nsp13468S468LtCatTa1414B.1.5970.064815
ORF1ab/nsp13468S468LtCatTa1214P.10.000189
ORF1ab/nsp13468S468LtCatTa1313B0.001662
ORF1ab/nsp13468S468LtCatTa1212B.1.3410.272727
ORF1ab/nsp13468S468LtCatTa88B.1.1.2140.000444
ORF1ab/nsp13468S468LtCatTa88B.1.6370.000585
ORF1ab/nsp13468S468LtCatTa88C.110.085106
ORF1ab/nsp13468S468LtCatTa77B.1.3690.001997
ORF1ab/nsp13468S468LtCatTa66AY.440.000037
ORF1ab/nsp13468S468LtCatTa66B.1.4290.000141
ORF1ab/nsp13468S468LtCatTa55AY.200.000194
ORF1ab/nsp13468S468LtCatTa55B.1.1.3330.005382
ORF1ab/nsp13468S468LtCatTa55B.1.2340.00066
ORF1ab/nsp13468S468LtCatTa55B.1.2400.001078
ORF1ab/nsp13468S468LtCatTa44AY.1030.000025
ORF1ab/nsp13468S468LtCatTa44AY.260.000113
ORF1ab/nsp13468S468LtCatTa44B.1.1.1290.036697
ORF1ab/nsp13468S468LtCatTa44B.1.177.40.000844
ORF1ab/nsp13468S468LtCatTa44B.1.2210.000284
ORF1ab/nsp13468S468LtCatTa44B.1.617.20.000015
ORF1ab/nsp13468S468LtCatTa33A0.001161
ORF1ab/nsp13468S468LtCatTa33AY.4.20.000065
ORF1ab/nsp13468S468LtCatTa33B.1.1.2840.000322
ORF1ab/nsp13468S468LtCatTa33B.1.1.3010.003538
ORF1ab/nsp13468S468LtCatTa33B.1.1.3110.001074
ORF1ab/nsp13468S468LtCatTa33B.1.1.770.125
ORF1ab/nsp13468S468LtCatTa33B.1.1600.000094
ORF1ab/nsp13468S468LtCatTa33B.1.177.730.001699
ORF1ab/nsp13468S468LtCatTa33B.1.2850.272727
ORF1ab/nsp13468S468LtCatTa33B.1.4370.0625
ORF1ab/nsp13468S468LtCatTa33B.1.5260.000071
ORF1ab/nsp13468S468LtCatTa33P.1.70.000958
ORF1ab/nsp13468S468LtCatTa22B.1.1.1210.004854
ORF1ab/nsp13468S468LtCatTa22B.1.1.1250.020408
ORF1ab/nsp13468S468LtCatTa22B.1.1.1740.006757
ORF1ab/nsp13468S468LtCatTa22B.1.1.2650.006309
ORF1ab/nsp13468S468LtCatTa22B.1.1.370.000386
ORF1ab/nsp13468S468LtCatTa22B.1.1.700.000682
ORF1ab/nsp13468S468LtCatTa22B.1.1110.00235
ORF1ab/nsp13468S468LtCatTa22B.1.177.100.001756
ORF1ab/nsp13468S468LtCatTa22B.1.1890.008584
ORF1ab/nsp13468S468LtCatTa22B.1.2430.000139
ORF1ab/nsp13468S468LtCatTa22B.1.2790.001027
ORF1ab/nsp13468S468LtCatTa22B.1.2840.026316
ORF1ab/nsp13468S468LtCatTa22B.1.3510.000059
ORF1ab/nsp13468S468LtCatTa22B.1.3560.003454
ORF1ab/nsp13468S468LtCatTa22B.1.36.100.009569
ORF1ab/nsp13468S468LtCatTa22B.1.36.80.002
ORF1ab/nsp13468S468LtCatTa22B.1.3980.005952
ORF1ab/nsp13468S468LtCatTa22B.1.438.10.000215
ORF1ab/nsp13468S468LtCatTa22B.1.5640.000852
ORF1ab/nsp13468S468LtCatTa22B.1.5800.00813
ORF1ab/nsp13468S468LtCatTa22B.1.6180.008065
ORF1ab/nsp13468S468LtCatTa22B.1.80.003945
ORF1ab/nsp13468S468LtCatTa11AY.16.10.00047
ORF1ab/nsp13468S468LtCatTa11AY.290.000016
ORF1ab/nsp13468S468LtCatTa11AY.320.000532
ORF1ab/nsp13468S468LtCatTa11AY.430.000004
ORF1ab/nsp13468S468LtCatTa11AY.460.000104
ORF1ab/nsp13468S468LtCatTa11AY.650.000533
ORF1ab/nsp13468S468LtCatTa11AY.750.000056
ORF1ab/nsp13468S468LtCatTa11AY.9.20.000037
ORF1ab/nsp13468S468LtCatTa11AY.980.000079
ORF1ab/nsp13468S468LtCatTa11B.1.1.10.000327
ORF1ab/nsp13468S468LtCatTa11B.1.1.1170.009709
ORF1ab/nsp13468S468LtCatTa11B.1.1.2070.001182
ORF1ab/nsp13468S468LtCatTa11B.1.1.2100.005714
ORF1ab/nsp13468S468LtCatTa11B.1.1.2220.000204
ORF1ab/nsp13468S468LtCatTa11B.1.1.2550.00303
ORF1ab/nsp13468S468LtCatTa11B.1.1.2630.001558
ORF1ab/nsp13468S468LtCatTa11B.1.1.2790.001121
ORF1ab/nsp13468S468LtCatTa11B.1.1.280.000311
ORF1ab/nsp13468S468LtCatTa11B.1.1.3120.001912
ORF1ab/nsp13468S468LtCatTa11B.1.1.3180.000302
ORF1ab/nsp13468S468LtCatTa11B.1.1.3720.000689
ORF1ab/nsp13468S468LtCatTa11B.1.1.390.00051
ORF1ab/nsp13468S468LtCatTa11B.1.1.4320.001266
ORF1ab/nsp13468S468LtCatTa11B.1.1.4860.001577
ORF1ab/nsp13468S468LtCatTa11B.1.1.5190.00004
ORF1ab/nsp13468S468LtCatTa11B.1.1.630.000386
ORF1ab/nsp13468S468LtCatTa11B.1.1.980.018519
ORF1ab/nsp13468S468LtCatTa11B.1.130.002375
ORF1ab/nsp13468S468LtCatTa11B.1.160.110.005714
ORF1ab/nsp13468S468LtCatTa11B.1.160.160.000929
ORF1ab/nsp13468S468LtCatTa11B.1.177.440.000519
ORF1ab/nsp13468S468LtCatTa11B.1.177.560.000668
ORF1ab/nsp13468S468LtCatTa11B.1.177.630.002703
ORF1ab/nsp13468S468LtCatTa11B.1.177.690.001484
ORF1ab/nsp13468S468LtCatTa11B.1.177.820.000477
ORF1ab/nsp13468S468LtCatTa11B.1.177.860.000183
ORF1ab/nsp13468S468LtCatTa11B.1.2230.002778
ORF1ab/nsp13468S468LtCatTa11B.1.2320.000537
ORF1ab/nsp13468S468LtCatTa11B.1.2350.002519
ORF1ab/nsp13468S468LtCatTa11B.1.2410.000812
ORF1ab/nsp13468S468LtCatTa11B.1.243.10.022222
ORF1ab/nsp13468S468LtCatTa11B.1.3490.000715
ORF1ab/nsp13468S468LtCatTa11B.1.351.50.0006
ORF1ab/nsp13468S468LtCatTa11B.1.360.000146
ORF1ab/nsp13468S468LtCatTa11B.1.3700.008
ORF1ab/nsp13468S468LtCatTa11B.1.3710.001122
ORF1ab/nsp13468S468LtCatTa11B.1.3750.00082
ORF1ab/nsp13468S468LtCatTa11B.1.3930.028571
ORF1ab/nsp13468S468LtCatTa11B.1.3950.007042
ORF1ab/nsp13468S468LtCatTa11B.1.3960.000706
ORF1ab/nsp13468S468LtCatTa11B.1.4030.003268
ORF1ab/nsp13468S468LtCatTa11B.1.4160.001269
ORF1ab/nsp13468S468LtCatTa11B.1.416.10.001563
ORF1ab/nsp13468S468LtCatTa11B.1.4320.011236
ORF1ab/nsp13468S468LtCatTa11B.1.4990.00105
ORF1ab/nsp13468S468LtCatTa11B.1.5030.002488
ORF1ab/nsp13468S468LtCatTa11B.1.5300.007143
ORF1ab/nsp13468S468LtCatTa11B.1.5400.009709
ORF1ab/nsp13468S468LtCatTa11B.1.5820.000491
ORF1ab/nsp13468S468LtCatTa11B.1.5880.00091
ORF1ab/nsp13468S468LtCatTa11B.1.595.40.007299
ORF1ab/nsp13468S468LtCatTa11B.1.6060.006024
ORF1ab/nsp13468S468LtCatTa11B.1.617.10.000129
ORF1ab/nsp13468S468LtCatTa11B.60.00091
ORF1ab/nsp13468S468LtCatTa11C.10.002392
ORF1ab/nsp13468S468LtCatTa11C.370.000116
ORF1ab/nsp13468S468LtCatTa11Q.10.000126
ORF1ab/nsp13468S468LtCatTa11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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