CoV-GLUE | Mutations | Mutation
CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : CodonNum = 439 & Codon = Aga
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
| ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
| ORF1ab/nsp13 | 439 | G439R | G5763R | nonsyn | Gga | Aga | 12173 | 12168 | 0.999589 | 17551-17553 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
| ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 12168 | 12173 | All | 0.002327 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 11087 | 11087 | R.1 | 0.99793 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 275 | 275 | B.1.1 | 0.004989 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 258 | 258 | B.1.258 | 0.017169 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 101 | 101 | B.1.1.220 | 0.187732 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 81 | 81 | B.1 | 0.000742 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 53 | 54 | AY.103 | 0.000329 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 51 | 52 | B.1.1.7 | 0.000046 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 34 | 34 | B.1.1.525 | 0.185792 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 27 | 28 | B.1.160 | 0.000842 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 18 | 18 | B.1.617.2 | 0.000068 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 17 | 17 | B.1.1.317 | 0.006999 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 13 | 13 | B.1.416 | 0.016497 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 12 | 12 | B.1.1.10 | 0.013378 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 11 | 11 | AY.4 | 0.000017 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 10 | 10 | B.1.2 | 0.000088 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 7 | 7 | AY.3 | 0.00007 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 7 | 7 | B.1.9.5 | 0.039773 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 6 | 6 | AY.44 | 0.000037 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 5 | 5 | AY.43 | 0.000022 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 5 | 5 | B.1.1.222 | 0.00102 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 4 | 4 | AY.25 | 0.000024 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 4 | 4 | B.1.177 | 0.000053 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 4 | 4 | B.1.177.32 | 0.005398 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 3 | 3 | AY.42 | 0.000121 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 3 | 3 | B.1.1.39 | 0.001529 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 3 | 3 | B.1.1.521 | 0.016043 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 3 | 3 | B.1.621 | 0.000266 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 2 | 2 | AY.102 | 0.000053 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 2 | 2 | AY.39 | 0.000049 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 2 | 2 | AY.61 | 0.00021 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 2 | 2 | B.1.1.214 | 0.000111 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 2 | 2 | B.1.1.291 | 0.001485 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 2 | 2 | B.1.1.51 | 0.003436 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 2 | 2 | B.1.1.83 | 0.00542 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 2 | 2 | B.1.429 | 0.000047 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 2 | 2 | B.1.631 | 0.006734 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 2 | 2 | P.1 | 0.000032 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | A | 0.000387 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | A.23.1 | 0.000704 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | A.28 | 0.002646 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | AY.120 | 0.000037 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | AY.16 | 0.00038 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | AY.18 | 0.010101 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | AY.23 | 0.00007 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | AY.38 | 0.000499 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | AY.49 | 0.003195 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | AY.54 | 0.000095 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | AY.6 | 0.000041 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | AY.98 | 0.000079 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.1.125 | 0.010204 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.1.196 | 0.005714 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.1.198 | 0.001468 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.1.236 | 0.006897 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.1.263 | 0.001558 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.1.305 | 0.003861 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.1.326 | 0.001761 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.1.33 | 0.000421 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.1.37 | 0.000193 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.1.464 | 0.001473 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.1.519 | 0.00004 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.1.522 | 0.017241 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.1.8 | 0.003584 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.161 | 0.017241 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.177.44 | 0.000519 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.177.75 | 0.001041 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.177.84 | 0.006667 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.214.2 | 0.0006 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.243 | 0.00007 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.258.21 | 0.007752 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.265 | 0.001271 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.277 | 0.02381 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.427 | 0.00005 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.466 | 0.023256 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.468 | 0.005714 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.533 | 0.009615 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.581 | 0.009434 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.617.1 | 0.000129 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.628 | 0.000352 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.1.93 | 0.000934 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | B.40 | 0.000364 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | P.1.12 | 0.000484 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | P.1.14 | 0.000048 |
| ORF1ab/nsp13 | 439 | G439R | Gga | Aga | 1 | 1 | Q.1 | 0.000126 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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