CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : CodonNum = 437

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13437F437FF5761FsynttCttT374374117545-17547
ORF1ab/nsp13437F437LF5761LnonsynTtcCtc39250.64102617545-17547
ORF1ab/nsp13437F437LF5761LnonsynttCttA39120.30769217545-17547
ORF1ab/nsp13437F437LF5761LnonsynttCttG3910.02564117545-17547
ORF1ab/nsp13437F437LF5761LnonsynTtCCtG3910.02564117545-17547
ORF1ab/nsp13437F437delF5761deldelTTC---2424117545-17547
ORF1ab/nsp13437F437VF5761VnonsynTtcGtc1616117545-17547
ORF1ab/nsp13437F437SF5761SnonsyntTctCc66117545-17547
ORF1ab/nsp13437F437YF5761YnonsyntTctAc44117545-17547
ORF1ab/nsp13437F437NF5761NnonsynTTcAAc22117545-17547
ORF1ab/nsp13437F437KF5761KnonsynTTCAAA22117545-17547
ORF1ab/nsp13437F437PF5761PnonsynTTcCCc22117545-17547
ORF1ab/nsp13437F437HF5761HnonsynTTcCAc22117545-17547
ORF1ab/nsp13437F437del1F5761del1delttCtt-22117545-17547
ORF1ab/nsp13437F437MF5761MnonsynTtCAtG11117545-17547
ORF1ab/nsp13437F437IF5761InonsynTtcAtc11117545-17547

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13437F437FttCttT374374All0.000072
ORF1ab/nsp13437F437FttCttT8989B.1.177.600.019441
ORF1ab/nsp13437F437FttCttT4444B.1.1.3430.916667
ORF1ab/nsp13437F437LTtcCtc2539All0.000005
ORF1ab/nsp13437F437LttCttA1239All0.000002
ORF1ab/nsp13437F437LTtCCtG139All0
ORF1ab/nsp13437F437LttCttG139All0
ORF1ab/nsp13437F437FttCttT3737AY.30.000368
ORF1ab/nsp13437F437FttCttT3232B.1.1.70.000029
ORF1ab/nsp13437F437delTTC---2424All0.000005
ORF1ab/nsp13437F437FttCttT2121B.1.5800.085366
ORF1ab/nsp13437F437VTtcGtc1616All0.000003
ORF1ab/nsp13437F437LTtcCtc1116B.10.000101
ORF1ab/nsp13437F437LttCttA516B.10.000046
ORF1ab/nsp13437F437FttCttT1616B.1.617.20.00006
ORF1ab/nsp13437F437FttCttT1414AY.40.000022
ORF1ab/nsp13437F437FttCttT1212AY.440.000073
ORF1ab/nsp13437F437delTTC---1212B.1.1.70.000011
ORF1ab/nsp13437F437FttCttT1010P.10.000158
ORF1ab/nsp13437F437StTctCc66All0.000001
ORF1ab/nsp13437F437FttCttT66B.10.000055
ORF1ab/nsp13437F437LTtcCtc56B.1.1.70.000004
ORF1ab/nsp13437F437LttCttA16B.1.1.70.000001
ORF1ab/nsp13437F437FttCttT55AY.110.006693
ORF1ab/nsp13437F437FttCttT55AY.470.000156
ORF1ab/nsp13437F437FttCttT55AY.690.000933
ORF1ab/nsp13437F437FttCttT55B.1.10.000091
ORF1ab/nsp13437F437YtTctAc44All0.000001
ORF1ab/nsp13437F437FttCttT44AY.250.000024
ORF1ab/nsp13437F437FttCttT44B.1.1.1890.006051
ORF1ab/nsp13437F437FttCttT44B.1.1770.000053
ORF1ab/nsp13437F437FttCttT33AY.140.000264
ORF1ab/nsp13437F437FttCttT33AY.430.000013
ORF1ab/nsp13437F437LTtcCtc33B.1.1770.00004
ORF1ab/nsp13437F437FttCttT33B.1.36.170.001482
ORF1ab/nsp13437F437HTTcCAc220.111111
ORF1ab/nsp13437F437PTTcCCc220.111111
ORF1ab/nsp13437F437YtTctAc220.111111
ORF1ab/nsp13437F437KTTCAAA220.111111
ORF1ab/nsp13437F437NTTcAAc220.111111
ORF1ab/nsp13437F437KTTCAAA22All0
ORF1ab/nsp13437F437HTTcCAc22All0
ORF1ab/nsp13437F437PTTcCCc22All0
ORF1ab/nsp13437F437del1ttCtt-22All0
ORF1ab/nsp13437F437NTTcAAc22All0
ORF1ab/nsp13437F437FttCttT22AY.1020.000053
ORF1ab/nsp13437F437FttCttT22AY.260.000057
ORF1ab/nsp13437F437FttCttT22AY.340.000194
ORF1ab/nsp13437F437delTTC---22AY.4.50.000215
ORF1ab/nsp13437F437FttCttT22AY.46.50.000397
ORF1ab/nsp13437F437FttCttT22AY.50.000041
ORF1ab/nsp13437F437FttCttT22AY.60.000082
ORF1ab/nsp13437F437VTtcGtc22AY.610.00021
ORF1ab/nsp13437F437FttCttT22AY.90.000135
ORF1ab/nsp13437F437FttCttT22B.1.1.250.001137
ORF1ab/nsp13437F437VTtcGtc22B.1.1.390.001019
ORF1ab/nsp13437F437LttCttA12B.1.1570.002985
ORF1ab/nsp13437F437LTtcCtc12B.1.1570.002985
ORF1ab/nsp13437F437VTtcGtc22B.1.1770.000026
ORF1ab/nsp13437F437VTtcGtc22B.1.177.230.006472
ORF1ab/nsp13437F437FttCttT22B.1.20.000018
ORF1ab/nsp13437F437LTtcCtc22B.1.3950.014085
ORF1ab/nsp13437F437FttCttT22B.1.6210.000177
ORF1ab/nsp13437F437FttCttT22R.10.00018
ORF1ab/nsp13437F437LttCttA11A0.000387
ORF1ab/nsp13437F437del1ttCtt-11A0.000387
ORF1ab/nsp13437F437delTTC---11AD.20.000219
ORF1ab/nsp13437F437MTtCAtG11All0
ORF1ab/nsp13437F437ITtcAtc11All0
ORF1ab/nsp13437F437FttCttT11AY.1000.000046
ORF1ab/nsp13437F437LttCttA11AY.1030.000006
ORF1ab/nsp13437F437FttCttT11AY.1140.000231
ORF1ab/nsp13437F437FttCttT11AY.116.10.000311
ORF1ab/nsp13437F437FttCttT11AY.1180.000063
ORF1ab/nsp13437F437FttCttT11AY.1190.000035
ORF1ab/nsp13437F437FttCttT11AY.120.10.000321
ORF1ab/nsp13437F437FttCttT11AY.200.000039
ORF1ab/nsp13437F437StTctCc11AY.250.000006
ORF1ab/nsp13437F437FttCttT11AY.290.000016
ORF1ab/nsp13437F437FttCttT11AY.29.10.000221
ORF1ab/nsp13437F437StTctCc11AY.30.00001
ORF1ab/nsp13437F437FttCttT11AY.360.000148
ORF1ab/nsp13437F437FttCttT11AY.390.000025
ORF1ab/nsp13437F437FttCttT11AY.4.20.000022
ORF1ab/nsp13437F437FttCttT11AY.420.00004
ORF1ab/nsp13437F437LttCttA11AY.430.000004
ORF1ab/nsp13437F437LttCttA11AY.440.000006
ORF1ab/nsp13437F437FttCttT11AY.450.000122
ORF1ab/nsp13437F437FttCttT11AY.590.00053
ORF1ab/nsp13437F437FttCttT11AY.610.000105
ORF1ab/nsp13437F437delTTC---11AY.670.000464
ORF1ab/nsp13437F437LTtcCtc11AY.690.000187
ORF1ab/nsp13437F437delTTC---11AY.99.10.001553
ORF1ab/nsp13437F437FttCttT11AZ.50.003509
ORF1ab/nsp13437F437FttCttT11B0.000128
ORF1ab/nsp13437F437VTtcGtc11B.10.000009
ORF1ab/nsp13437F437delTTC---11B.10.000009
ORF1ab/nsp13437F437StTctCc11B.1.10.000018
ORF1ab/nsp13437F437MTtCAtG11B.1.10.000018
ORF1ab/nsp13437F437LTtCCtG11B.1.10.000018
ORF1ab/nsp13437F437ITtcAtc11B.1.10.000018
ORF1ab/nsp13437F437VTtcGtc11B.1.10.000018
ORF1ab/nsp13437F437StTctCc11B.1.1.1250.010204
ORF1ab/nsp13437F437VTtcGtc11B.1.1.1440.028571
ORF1ab/nsp13437F437FttCttT11B.1.1.2160.00089
ORF1ab/nsp13437F437VTtcGtc11B.1.1.2690.001353
ORF1ab/nsp13437F437FttCttT11B.1.1.3160.000925
ORF1ab/nsp13437F437LttCttA11B.1.1600.000031
ORF1ab/nsp13437F437VTtcGtc11B.1.1600.000031
ORF1ab/nsp13437F437del1ttCtt-11B.1.1770.000013
ORF1ab/nsp13437F437StTctCc11B.1.1770.000013
ORF1ab/nsp13437F437VTtcGtc11B.1.177.440.000519
ORF1ab/nsp13437F437FttCttT11B.1.177.790.002342
ORF1ab/nsp13437F437delTTC---11B.1.1790.003759
ORF1ab/nsp13437F437StTctCc11B.1.20.000009
ORF1ab/nsp13437F437LTtcCtc11B.1.2060.000816
ORF1ab/nsp13437F437FttCttT11B.1.2340.000132
ORF1ab/nsp13437F437delTTC---11B.1.2580.000067
ORF1ab/nsp13437F437VTtcGtc11B.1.2580.000067
ORF1ab/nsp13437F437FttCttT11B.1.3510.00003
ORF1ab/nsp13437F437FttCttT11B.1.36.240.006173
ORF1ab/nsp13437F437delTTC---11B.1.4150.014286
ORF1ab/nsp13437F437VTtcGtc11B.1.416.10.001563
ORF1ab/nsp13437F437FttCttT11B.1.4290.000024
ORF1ab/nsp13437F437YtTctAc11B.1.5260.000024
ORF1ab/nsp13437F437FttCttT11B.1.5960.000087
ORF1ab/nsp13437F437FttCttT11B.1.617.10.000129
ORF1ab/nsp13437F437LTtcCtc11B.1.617.20.000004
ORF1ab/nsp13437F437YtTctAc11B.1.617.20.000004
ORF1ab/nsp13437F437delTTC---11B.1.617.20.000004
ORF1ab/nsp13437F437delTTC---11B.1.6300.005236
ORF1ab/nsp13437F437LttCttG11C.170.055556
ORF1ab/nsp13437F437FttCttT11C.370.000116
ORF1ab/nsp13437F437FttCttT11P.1.140.000048
ORF1ab/nsp13437F437FttCttT11P.30.001595
ORF1ab/nsp13437F437delTTC---11U.30.003861

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.