CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : CodonNum = 427

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13427R427KR5751KnonsynaGaaAa107107117515-17517
ORF1ab/nsp13427R427IR5751InonsynaGaaTa1071060.99065417515-17517
ORF1ab/nsp13427R427IR5751InonsynaGAaTC10710.0093457917515-17517
ORF1ab/nsp13427R427RR5751RsynagAagG74680.91891917515-17517
ORF1ab/nsp13427R427RR5751RsynAgaCga7450.067567617515-17517
ORF1ab/nsp13427R427RR5751RsynAgACgT7410.013513517515-17517
ORF1ab/nsp13427R427GR5751GnonsynAgaGga1919117515-17517
ORF1ab/nsp13427R427delR5751deldelAGA---1919117515-17517
ORF1ab/nsp13427R427TR5751TnonsynaGaaCa1313117515-17517
ORF1ab/nsp13427R427SR5751SnonsynagAagT750.71428617515-17517
ORF1ab/nsp13427R427SR5751SnonsynagAagC710.14285717515-17517
ORF1ab/nsp13427R427SR5751SnonsynAGaTCa710.14285717515-17517
ORF1ab/nsp13427R427XR5751XnonsynAgaTga55117515-17517
ORF1ab/nsp13427R427del2R5751del2delAGa--a22117515-17517
ORF1ab/nsp13427R427NR5751NnonsynaGAaAC22117515-17517
ORF1ab/nsp13427R427del1R5751del1delAga-ga210.517515-17517
ORF1ab/nsp13427R427del1R5751del1delAGa-Aa210.517515-17517
ORF1ab/nsp13427R427LR5751LnonsynAGaCTa11117515-17517
ORF1ab/nsp13427R427FR5751FnonsynAGATTT11117515-17517

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13427R427KaGaaAa107107All0.00002
ORF1ab/nsp13427R427IaGaaTa106107All0.00002
ORF1ab/nsp13427R427IaGAaTC1107All0
ORF1ab/nsp13427R427RagAagG6874All0.000013
ORF1ab/nsp13427R427RAgaCga574All0.000001
ORF1ab/nsp13427R427RAgACgT174All0
ORF1ab/nsp13427R427IaGaaTa3434AY.40.000053
ORF1ab/nsp13427R427KaGaaAa2929B.1.1.70.000026
ORF1ab/nsp13427R427KaGaaAa2525B.1.1.3250.641026
ORF1ab/nsp13427R427IaGaaTa2323AY.4.50.002472
ORF1ab/nsp13427R427GAgaGga1919All0.000004
ORF1ab/nsp13427R427delAGA---1919All0.000004
ORF1ab/nsp13427R427RagAagG1919AY.1030.000118
ORF1ab/nsp13427R427TaGaaCa1313All0.000002
ORF1ab/nsp13427R427IaGaaTa1011B.1.10.000181
ORF1ab/nsp13427R427IaGAaTC111B.1.10.000018
ORF1ab/nsp13427R427RagAagG1011B.1.1.70.000009
ORF1ab/nsp13427R427RAgaCga111B.1.1.70.000001
ORF1ab/nsp13427R427KaGaaAa1010B.1.6000.05848
ORF1ab/nsp13427R427delAGA---99B.1.1.70.000008
ORF1ab/nsp13427R427KaGaaAa99B.1.360.001313
ORF1ab/nsp13427R427SagAagT57All0.000001
ORF1ab/nsp13427R427SAGaTCa17All0
ORF1ab/nsp13427R427SagAagC17All0
ORF1ab/nsp13427R427GAgaGga77AY.40.000011
ORF1ab/nsp13427R427TaGaaCa660.333333
ORF1ab/nsp13427R427RagAagG66AY.290.000095
ORF1ab/nsp13427R427XAgaTga55All0.000001
ORF1ab/nsp13427R427IaGaaTa55AY.90.000338
ORF1ab/nsp13427R427RagAagG55B.10.000046
ORF1ab/nsp13427R427IaGaaTa44AY.80.002424
ORF1ab/nsp13427R427RagAagG44B.1.2320.002149
ORF1ab/nsp13427R427IaGaaTa44B.1.2430.000278
ORF1ab/nsp13427R427RagAagG44B.1.617.20.000015
ORF1ab/nsp13427R427KaGaaAa44B.1.617.20.000015
ORF1ab/nsp13427R427RagAagG23AY.40.000003
ORF1ab/nsp13427R427RAgaCga13AY.40.000002
ORF1ab/nsp13427R427KaGaaAa33AY.980.000237
ORF1ab/nsp13427R427IaGaaTa33B.1.1.70.000003
ORF1ab/nsp13427R427KaGaaAa33B.1.1600.000094
ORF1ab/nsp13427R427KaGaaAa33B.1.20.000026
ORF1ab/nsp13427R427GAgaGga33B.1.617.20.000011
ORF1ab/nsp13427R427KaGaaAa33P.10.000047
ORF1ab/nsp13427R427NaGAaAC220.111111
ORF1ab/nsp13427R427NaGAaAC22All0
ORF1ab/nsp13427R427del2AGa--a22All0
ORF1ab/nsp13427R427del1AGa-Aa12All0
ORF1ab/nsp13427R427del1Aga-ga12All0
ORF1ab/nsp13427R427IaGaaTa22AY.1200.000074
ORF1ab/nsp13427R427TaGaaCa22AY.250.000012
ORF1ab/nsp13427R427KaGaaAa22AY.250.000012
ORF1ab/nsp13427R427RagAagG22AY.430.000009
ORF1ab/nsp13427R427IaGaaTa22AY.580.001815
ORF1ab/nsp13427R427IaGaaTa22B.10.000018
ORF1ab/nsp13427R427SagAagT12B.1.10.000018
ORF1ab/nsp13427R427SagAagC12B.1.10.000018
ORF1ab/nsp13427R427RagAagG22B.1.1.5190.000079
ORF1ab/nsp13427R427SagAagT22B.1.1.70.000002
ORF1ab/nsp13427R427TaGaaCa22B.1.1.70.000002
ORF1ab/nsp13427R427RagAagG22B.1.20.000018
ORF1ab/nsp13427R427IaGaaTa22B.1.20.000018
ORF1ab/nsp13427R427GAgaGga22B.1.2210.000142
ORF1ab/nsp13427R427delAGA---11AD.20.000219
ORF1ab/nsp13427R427LAGaCTa11All0
ORF1ab/nsp13427R427FAGATTT11All0
ORF1ab/nsp13427R427XAgaTga11AY.1030.000006
ORF1ab/nsp13427R427RagAagG11AY.1130.000142
ORF1ab/nsp13427R427SagAagT11AY.1140.000231
ORF1ab/nsp13427R427RAgaCga11AY.1190.000035
ORF1ab/nsp13427R427KaGaaAa11AY.160.00038
ORF1ab/nsp13427R427IaGaaTa11AY.170.008197
ORF1ab/nsp13427R427GAgaGga11AY.250.000006
ORF1ab/nsp13427R427RagAagG11AY.340.000097
ORF1ab/nsp13427R427RagAagG11AY.360.000148
ORF1ab/nsp13427R427RagAagG11AY.390.000025
ORF1ab/nsp13427R427KaGaaAa11AY.40.000002
ORF1ab/nsp13427R427SAGaTCa11AY.420.00004
ORF1ab/nsp13427R427IaGaaTa11AY.430.000004
ORF1ab/nsp13427R427delAGA---11AY.430.000004
ORF1ab/nsp13427R427KaGaaAa11AY.440.000006
ORF1ab/nsp13427R427RagAagG11AY.50.000021
ORF1ab/nsp13427R427RagAagG11AY.5.30.000337
ORF1ab/nsp13427R427RagAagG11AY.550.000917
ORF1ab/nsp13427R427FAGATTT11AY.620.000436
ORF1ab/nsp13427R427RAgACgT11AY.670.000464
ORF1ab/nsp13427R427IaGaaTa11AY.870.000833
ORF1ab/nsp13427R427IaGaaTa11AY.9.20.000037
ORF1ab/nsp13427R427delAGA---11AY.99.10.001553
ORF1ab/nsp13427R427TaGaaCa11B.10.000009
ORF1ab/nsp13427R427XAgaTga11B.1.10.000018
ORF1ab/nsp13427R427KaGaaAa11B.1.10.000018
ORF1ab/nsp13427R427RAgaCga11B.1.10.000018
ORF1ab/nsp13427R427LAGaCTa11B.1.10.000018
ORF1ab/nsp13427R427KaGaaAa11B.1.1.1530.001095
ORF1ab/nsp13427R427KaGaaAa11B.1.1.1980.001468
ORF1ab/nsp13427R427IaGaaTa11B.1.1.2160.00089
ORF1ab/nsp13427R427SagAagT11B.1.1.2160.00089
ORF1ab/nsp13427R427RagAagG11B.1.1.2550.00303
ORF1ab/nsp13427R427KaGaaAa11B.1.1.3330.001076
ORF1ab/nsp13427R427IaGaaTa11B.1.1.630.000386
ORF1ab/nsp13427R427del2AGa--a11B.1.1.70.000001
ORF1ab/nsp13427R427XAgaTga11B.1.1.70.000001
ORF1ab/nsp13427R427GAgaGga11B.1.1.70.000001
ORF1ab/nsp13427R427GAgaGga11B.1.1600.000031
ORF1ab/nsp13427R427RagAagG11B.1.1600.000031
ORF1ab/nsp13427R427GAgaGga11B.1.1770.000013
ORF1ab/nsp13427R427del2AGa--a11B.1.177.570.000281
ORF1ab/nsp13427R427del1Aga-ga11B.1.177.690.001484
ORF1ab/nsp13427R427RagAagG11B.1.177.70.000165
ORF1ab/nsp13427R427delAGA---11B.1.177.760.002494
ORF1ab/nsp13427R427GAgaGga11B.1.177.90.001332
ORF1ab/nsp13427R427delAGA---11B.1.1790.003759
ORF1ab/nsp13427R427KaGaaAa11B.1.2340.000132
ORF1ab/nsp13427R427TaGaaCa11B.1.2400.000216
ORF1ab/nsp13427R427delAGA---11B.1.2580.000067
ORF1ab/nsp13427R427GAgaGga11B.1.258.70.001912
ORF1ab/nsp13427R427GAgaGga11B.1.3670.000792
ORF1ab/nsp13427R427IaGaaTa11B.1.3690.000285
ORF1ab/nsp13427R427del1AGa-Aa11B.1.3770.004566
ORF1ab/nsp13427R427delAGA---11B.1.4150.014286
ORF1ab/nsp13427R427KaGaaAa11B.1.4270.00005
ORF1ab/nsp13427R427KaGaaAa11B.1.4290.000024
ORF1ab/nsp13427R427KaGaaAa11B.1.466.20.000391
ORF1ab/nsp13427R427IaGaaTa11B.1.5640.000426
ORF1ab/nsp13427R427KaGaaAa11B.1.5770.000687
ORF1ab/nsp13427R427XAgaTga11B.1.5950.000261
ORF1ab/nsp13427R427IaGaaTa11B.1.5960.000087
ORF1ab/nsp13427R427KaGaaAa11B.1.5960.000087
ORF1ab/nsp13427R427IaGaaTa11B.1.5990.00365
ORF1ab/nsp13427R427KaGaaAa11B.1.6090.000479
ORF1ab/nsp13427R427delAGA---11B.1.617.20.000004
ORF1ab/nsp13427R427IaGaaTa11B.1.617.20.000004
ORF1ab/nsp13427R427RAgaCga11B.1.621.10.000506
ORF1ab/nsp13427R427IaGaaTa11B.1.6230.000536
ORF1ab/nsp13427R427delAGA---11B.1.6300.005236
ORF1ab/nsp13427R427IaGaaTa11B.60.00091
ORF1ab/nsp13427R427KaGaaAa11C.1.20.004255
ORF1ab/nsp13427R427IaGaaTa11C.350.000774
ORF1ab/nsp13427R427IaGaaTa11D.20.000075
ORF1ab/nsp13427R427RagAagG11P.10.000016
ORF1ab/nsp13427R427XAgaTga11P.1.140.000048
ORF1ab/nsp13427R427KaGaaAa11P.1.160.000374
ORF1ab/nsp13427R427RagAagG11P.1.170.000162
ORF1ab/nsp13427R427delAGA---11U.30.003861
ORF1ab/nsp13427R427TaGaaCa11W.40.001351

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.