CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : CodonNum = 367

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13367T367TT5691TsynacAacG12810127550.99570617335-17337
ORF1ab/nsp13367T367TT5691TsynacAacC12810430.0033567517335-17337
ORF1ab/nsp13367T367TT5691TsynacAacT12810120.00093676817335-17337
ORF1ab/nsp13367T367IT5691InonsynaCaaTa46484648117335-17337
ORF1ab/nsp13367T367AT5691AnonsynAcaGca155155117335-17337
ORF1ab/nsp13367T367PT5691PnonsynAcaCca2121117335-17337
ORF1ab/nsp13367T367RT5691RnonsynaCaaGa1616117335-17337
ORF1ab/nsp13367T367delT5691deldelACA---33117335-17337
ORF1ab/nsp13367T367ST5691SnonsynAcaTca22117335-17337
ORF1ab/nsp13367T367KT5691KnonsynaCaaAa22117335-17337
ORF1ab/nsp13367T367MT5691MnonsynaCAaTG11117335-17337

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13367T367TacAacG1275512810All0.00244
ORF1ab/nsp13367T367TacAacC4312810All0.000008
ORF1ab/nsp13367T367TacAacT1212810All0.000002
ORF1ab/nsp13367T367TacAacG1075810767B.1.1.70.009631
ORF1ab/nsp13367T367TacAacT610767B.1.1.70.000005
ORF1ab/nsp13367T367TacAacC310767B.1.1.70.000003
ORF1ab/nsp13367T367IaCaaTa46484648All0.000889
ORF1ab/nsp13367T367IaCaaTa27962796AY.20.995726
ORF1ab/nsp13367T367TacAacG948948D.20.071139
ORF1ab/nsp13367T367TacAacG888888Q.70.986667
ORF1ab/nsp13367T367IaCaaTa531531AY.440.003232
ORF1ab/nsp13367T367AAcaGca155155All0.00003
ORF1ab/nsp13367T367IaCaaTa129129AY.790.156174
ORF1ab/nsp13367T367IaCaaTa129129B.1.617.20.000486
ORF1ab/nsp13367T367IaCaaTa116116AY.40.000181
ORF1ab/nsp13367T367IaCaaTa9292B.1.20.00081
ORF1ab/nsp13367T367IaCaaTa8787B.1.1.70.000078
ORF1ab/nsp13367T367AAcaGca8585B.1.1.70.000076
ORF1ab/nsp13367T367IaCaaTa6060B.1.5260.00141
ORF1ab/nsp13367T367IaCaaTa5555AY.46.40.009048
ORF1ab/nsp13367T367IaCaaTa4141AY.1030.000255
ORF1ab/nsp13367T367IaCaaTa4141B.10.000376
ORF1ab/nsp13367T367TacAacG3636AY.440.000219
ORF1ab/nsp13367T367TacAacC2530B.1.617.20.000094
ORF1ab/nsp13367T367TacAacG430B.1.617.20.000015
ORF1ab/nsp13367T367TacAacT130B.1.617.20.000004
ORF1ab/nsp13367T367IaCaaTa2828AY.250.000168
ORF1ab/nsp13367T367IaCaaTa2727AY.430.00012
ORF1ab/nsp13367T367IaCaaTa2727AY.710.012827
ORF1ab/nsp13367T367TacAacG2324B.1.20.000203
ORF1ab/nsp13367T367TacAacC124B.1.20.000009
ORF1ab/nsp13367T367IaCaaTa2323B.1.1.5190.000913
ORF1ab/nsp13367T367PAcaCca2121All0.000004
ORF1ab/nsp13367T367IaCaaTa2121AY.620.00915
ORF1ab/nsp13367T367IaCaaTa2020AY.390.000494
ORF1ab/nsp13367T367IaCaaTa1919AY.260.000538
ORF1ab/nsp13367T367IaCaaTa1919AY.750.001064
ORF1ab/nsp13367T367IaCaaTa1717AY.1000.000782
ORF1ab/nsp13367T367RaCaaGa1616All0.000003
ORF1ab/nsp13367T367IaCaaTa1515AY.30.000149
ORF1ab/nsp13367T367IaCaaTa1515B.1.1770.000198
ORF1ab/nsp13367T367AAcaGca1515B.1.5170.006405
ORF1ab/nsp13367T367IaCaaTa1414AY.120.20.017995
ORF1ab/nsp13367T367IaCaaTa1414AY.290.000221
ORF1ab/nsp13367T367IaCaaTa1414AY.370.004425
ORF1ab/nsp13367T367AAcaGca1414AY.40.000022
ORF1ab/nsp13367T367IaCaaTa1313AY.380.00649
ORF1ab/nsp13367T367IaCaaTa1313AY.420.000523
ORF1ab/nsp13367T367TacAacG1313B.1.10.000236
ORF1ab/nsp13367T367IaCaaTa1313B.1.36.10.014823
ORF1ab/nsp13367T367IaCaaTa1212AY.1020.000318
ORF1ab/nsp13367T367IaCaaTa1010AY.116.10.003114
ORF1ab/nsp13367T367AAcaGca1010B.1.5960.000871
ORF1ab/nsp13367T367TacAacG1010Q.10.001263
ORF1ab/nsp13367T367TacAacG99AY.40.000014
ORF1ab/nsp13367T367IaCaaTa99B.1.3510.000268
ORF1ab/nsp13367T367IaCaaTa99P.10.000142
ORF1ab/nsp13367T367TacAacC78AY.1020.000186
ORF1ab/nsp13367T367TacAacG18AY.1020.000027
ORF1ab/nsp13367T367RaCaaGa88B.1.5250.000905
ORF1ab/nsp13367T367PAcaCca88B.1.617.10.001032
ORF1ab/nsp13367T367TacAacG77AY.430.000031
ORF1ab/nsp13367T367IaCaaTa77AY.520.0057
ORF1ab/nsp13367T367IaCaaTa77AY.650.003731
ORF1ab/nsp13367T367IaCaaTa77AY.75.10.001262
ORF1ab/nsp13367T367RaCaaGa77B.1.1.70.000006
ORF1ab/nsp13367T367IaCaaTa77B.1.4290.000165
ORF1ab/nsp13367T367IaCaaTa66AY.10.002374
ORF1ab/nsp13367T367TacAacG66AY.1030.000037
ORF1ab/nsp13367T367IaCaaTa66AY.1180.000376
ORF1ab/nsp13367T367IaCaaTa66AY.470.000187
ORF1ab/nsp13367T367IaCaaTa66AY.99.20.000553
ORF1ab/nsp13367T367TacAacG46B.10.000037
ORF1ab/nsp13367T367TacAacC26B.10.000018
ORF1ab/nsp13367T367IaCaaTa66B.1.6210.000531
ORF1ab/nsp13367T367TacAacG55B.1.3510.000149
ORF1ab/nsp13367T367IaCaaTa44AY.100.00212
ORF1ab/nsp13367T367TacAacG34AY.250.000018
ORF1ab/nsp13367T367TacAacT14AY.250.000006
ORF1ab/nsp13367T367IaCaaTa44AY.4.20.000087
ORF1ab/nsp13367T367IaCaaTa44AY.9.20.000147
ORF1ab/nsp13367T367AAcaGca44B.10.000037
ORF1ab/nsp13367T367IaCaaTa44B.1.5960.000349
ORF1ab/nsp13367T367delACA---33All0.000001
ORF1ab/nsp13367T367PAcaCca33AY.1030.000019
ORF1ab/nsp13367T367IaCaaTa33AY.1060.001005
ORF1ab/nsp13367T367IaCaaTa33AY.200.000117
ORF1ab/nsp13367T367IaCaaTa33AY.230.000209
ORF1ab/nsp13367T367TacAacG33AY.30.00003
ORF1ab/nsp13367T367IaCaaTa33AY.3.10.000256
ORF1ab/nsp13367T367IaCaaTa33AY.340.000291
ORF1ab/nsp13367T367IaCaaTa33AY.50.000062
ORF1ab/nsp13367T367IaCaaTa33AY.740.000347
ORF1ab/nsp13367T367IaCaaTa33AY.960.006224
ORF1ab/nsp13367T367IaCaaTa33AY.98.10.000145
ORF1ab/nsp13367T367IaCaaTa33B.1.10.000054
ORF1ab/nsp13367T367AAcaGca33B.1.10.000054
ORF1ab/nsp13367T367IaCaaTa33B.1.1.2410.006211
ORF1ab/nsp13367T367TacAacG33B.1.1.570.034483
ORF1ab/nsp13367T367PAcaCca33B.1.1770.00004
ORF1ab/nsp13367T367IaCaaTa33B.1.1790.011278
ORF1ab/nsp13367T367IaCaaTa33B.1.6280.001057
ORF1ab/nsp13367T367IaCaaTa33C.370.000348
ORF1ab/nsp13367T367IaCaaTa33P.1.160.001122
ORF1ab/nsp13367T367SAcaTca22All0
ORF1ab/nsp13367T367KaCaaAa22All0
ORF1ab/nsp13367T367AAcaGca22AY.1030.000012
ORF1ab/nsp13367T367TacAacG22AY.1160.000574
ORF1ab/nsp13367T367IaCaaTa22AY.1170.000169
ORF1ab/nsp13367T367TacAacG22AY.1190.000071
ORF1ab/nsp13367T367IaCaaTa22AY.1190.000071
ORF1ab/nsp13367T367IaCaaTa22AY.190.002281
ORF1ab/nsp13367T367AAcaGca22AY.290.000032
ORF1ab/nsp13367T367PAcaCca22AY.330.000134
ORF1ab/nsp13367T367TacAacC22AY.39.10.000079
ORF1ab/nsp13367T367IaCaaTa22AY.4.30.001684
ORF1ab/nsp13367T367TacAacG22AY.4.50.000215
ORF1ab/nsp13367T367IaCaaTa22AY.410.000588
ORF1ab/nsp13367T367IaCaaTa22AY.450.000243
ORF1ab/nsp13367T367IaCaaTa22AY.510.001818
ORF1ab/nsp13367T367IaCaaTa22AY.590.001059
ORF1ab/nsp13367T367IaCaaTa22AY.850.000854
ORF1ab/nsp13367T367IaCaaTa22AY.860.00166
ORF1ab/nsp13367T367IaCaaTa22AY.90.000135
ORF1ab/nsp13367T367IaCaaTa22AY.950.001522
ORF1ab/nsp13367T367IaCaaTa22B0.000256
ORF1ab/nsp13367T367IaCaaTa22B.1.1.2140.000111
ORF1ab/nsp13367T367IaCaaTa22B.1.1.2840.000215
ORF1ab/nsp13367T367IaCaaTa22B.1.1.4480.004065
ORF1ab/nsp13367T367IaCaaTa22B.1.1.4640.002946
ORF1ab/nsp13367T367TacAacG22B.1.1600.000062
ORF1ab/nsp13367T367TacAacG22B.1.1770.000026
ORF1ab/nsp13367T367IaCaaTa22B.1.177.210.000153
ORF1ab/nsp13367T367IaCaaTa22B.1.177.40.000422
ORF1ab/nsp13367T367AAcaGca22B.1.177.750.002081
ORF1ab/nsp13367T367IaCaaTa22B.1.2400.000431
ORF1ab/nsp13367T367IaCaaTa22B.1.2430.000139
ORF1ab/nsp13367T367IaCaaTa22B.1.360.000292
ORF1ab/nsp13367T367IaCaaTa22B.1.5250.000226
ORF1ab/nsp13367T367TacAacG12B.1.617.10.000129
ORF1ab/nsp13367T367TacAacC12B.1.617.10.000129
ORF1ab/nsp13367T367TacAacT11A.20.000662
ORF1ab/nsp13367T367IaCaaTa11AE.50.018519
ORF1ab/nsp13367T367MaCAaTG11All0
ORF1ab/nsp13367T367delACA---11AU.30.00211
ORF1ab/nsp13367T367TacAacG11AY.1000.000046
ORF1ab/nsp13367T367IaCaaTa11AY.1070.000466
ORF1ab/nsp13367T367TacAacT11AY.1100.000113
ORF1ab/nsp13367T367IaCaaTa11AY.1100.000113
ORF1ab/nsp13367T367IaCaaTa11AY.1140.000231
ORF1ab/nsp13367T367TacAacG11AY.1170.000085
ORF1ab/nsp13367T367AAcaGca11AY.1200.000037
ORF1ab/nsp13367T367IaCaaTa11AY.1200.000037
ORF1ab/nsp13367T367TacAacG11AY.120.10.000321
ORF1ab/nsp13367T367IaCaaTa11AY.1210.000135
ORF1ab/nsp13367T367TacAacG11AY.130.000161
ORF1ab/nsp13367T367TacAacG11AY.140.000088
ORF1ab/nsp13367T367IaCaaTa11AY.160.00038
ORF1ab/nsp13367T367IaCaaTa11AY.16.10.00047
ORF1ab/nsp13367T367TacAacG11AY.200.000039
ORF1ab/nsp13367T367PAcaCca11AY.260.000028
ORF1ab/nsp13367T367AAcaGca11AY.260.000028
ORF1ab/nsp13367T367IaCaaTa11AY.270.000065
ORF1ab/nsp13367T367IaCaaTa11AY.29.10.000221
ORF1ab/nsp13367T367AAcaGca11AY.3.10.000085
ORF1ab/nsp13367T367AAcaGca11AY.330.000067
ORF1ab/nsp13367T367IaCaaTa11AY.330.000067
ORF1ab/nsp13367T367TacAacG11AY.350.000233
ORF1ab/nsp13367T367AAcaGca11AY.390.000025
ORF1ab/nsp13367T367IaCaaTa11AY.39.10.00004
ORF1ab/nsp13367T367PAcaCca11AY.4.40.000409
ORF1ab/nsp13367T367IaCaaTa11AY.4.50.000107
ORF1ab/nsp13367T367AAcaGca11AY.420.00004
ORF1ab/nsp13367T367AAcaGca11AY.440.000006
ORF1ab/nsp13367T367TacAacC11AY.46.40.000165
ORF1ab/nsp13367T367PAcaCca11AY.50.000021
ORF1ab/nsp13367T367IaCaaTa11AY.5.40.000277
ORF1ab/nsp13367T367IaCaaTa11AY.500.000799
ORF1ab/nsp13367T367TacAacC11AY.530.000288
ORF1ab/nsp13367T367IaCaaTa11AY.560.001605
ORF1ab/nsp13367T367IaCaaTa11AY.60.000041
ORF1ab/nsp13367T367IaCaaTa11AY.600.000938
ORF1ab/nsp13367T367IaCaaTa11AY.610.000105
ORF1ab/nsp13367T367IaCaaTa11AY.640.000595
ORF1ab/nsp13367T367IaCaaTa11AY.670.000464
ORF1ab/nsp13367T367IaCaaTa11AY.680.000274
ORF1ab/nsp13367T367TacAacG11AY.690.000187
ORF1ab/nsp13367T367IaCaaTa11AY.730.000665
ORF1ab/nsp13367T367AAcaGca11AY.750.000056
ORF1ab/nsp13367T367AAcaGca11AY.820.001357
ORF1ab/nsp13367T367TacAacG11AY.9.20.000037
ORF1ab/nsp13367T367IaCaaTa11AY.930.000273
ORF1ab/nsp13367T367IaCaaTa11AY.980.000079
ORF1ab/nsp13367T367TacAacG11B.1.1.1610.003534
ORF1ab/nsp13367T367AAcaGca11B.1.1.1980.001468
ORF1ab/nsp13367T367IaCaaTa11B.1.1.2200.001859
ORF1ab/nsp13367T367TacAacG11B.1.1.250.000569
ORF1ab/nsp13367T367IaCaaTa11B.1.1.2630.001558
ORF1ab/nsp13367T367TacAacG11B.1.1.3180.000302
ORF1ab/nsp13367T367IaCaaTa11B.1.1.3490.010309
ORF1ab/nsp13367T367IaCaaTa11B.1.1.4020.011111
ORF1ab/nsp13367T367IaCaaTa11B.1.1.580.005376
ORF1ab/nsp13367T367MaCAaTG11B.1.1.70.000001
ORF1ab/nsp13367T367PAcaCca11B.1.1.70.000001
ORF1ab/nsp13367T367SAcaTca11B.1.1.70.000001
ORF1ab/nsp13367T367KaCaaAa11B.1.1.70.000001
ORF1ab/nsp13367T367IaCaaTa11B.1.1600.000031
ORF1ab/nsp13367T367AAcaGca11B.1.1770.000013
ORF1ab/nsp13367T367TacAacT11B.1.177.310.011494
ORF1ab/nsp13367T367IaCaaTa11B.1.177.310.011494
ORF1ab/nsp13367T367IaCaaTa11B.1.177.350.000691
ORF1ab/nsp13367T367TacAacG11B.1.177.730.000566
ORF1ab/nsp13367T367IaCaaTa11B.1.177.820.000477
ORF1ab/nsp13367T367TacAacG11B.1.214.20.0006
ORF1ab/nsp13367T367TacAacG11B.1.2210.000071
ORF1ab/nsp13367T367IaCaaTa11B.1.2290.009709
ORF1ab/nsp13367T367IaCaaTa11B.1.258.110.000396
ORF1ab/nsp13367T367IaCaaTa11B.1.258.170.000104
ORF1ab/nsp13367T367TacAacG11B.1.258.170.000104
ORF1ab/nsp13367T367IaCaaTa11B.1.2890.00266
ORF1ab/nsp13367T367IaCaaTa11B.1.3010.005917
ORF1ab/nsp13367T367AAcaGca11B.1.360.000146
ORF1ab/nsp13367T367TacAacG11B.1.360.000146
ORF1ab/nsp13367T367IaCaaTa11B.1.36.310.001751
ORF1ab/nsp13367T367IaCaaTa11B.1.36.360.000602
ORF1ab/nsp13367T367IaCaaTa11B.1.3690.000285
ORF1ab/nsp13367T367TacAacT11B.1.4270.00005
ORF1ab/nsp13367T367TacAacG11B.1.4290.000024
ORF1ab/nsp13367T367AAcaGca11B.1.4290.000024
ORF1ab/nsp13367T367IaCaaTa11B.1.438.10.000107
ORF1ab/nsp13367T367AAcaGca11B.1.5030.002488
ORF1ab/nsp13367T367AAcaGca11B.1.5260.000024
ORF1ab/nsp13367T367IaCaaTa11B.1.5640.000426
ORF1ab/nsp13367T367TacAacG11B.1.5950.000261
ORF1ab/nsp13367T367IaCaaTa11B.1.5970.00463
ORF1ab/nsp13367T367TacAacG11B.1.6090.000479
ORF1ab/nsp13367T367AAcaGca11B.1.617.20.000004
ORF1ab/nsp13367T367TacAacG11B.1.6210.000089
ORF1ab/nsp13367T367RaCaaGa11B.1.6360.006711
ORF1ab/nsp13367T367delACA---11B.340.013699
ORF1ab/nsp13367T367PAcaCca11B.350.007812
ORF1ab/nsp13367T367AAcaGca11B.550.00295
ORF1ab/nsp13367T367SAcaTca11C.350.000774
ORF1ab/nsp13367T367TacAacG11C.370.000116
ORF1ab/nsp13367T367IaCaaTa11L.10.001905
ORF1ab/nsp13367T367AAcaGca11P.10.000016
ORF1ab/nsp13367T367delACA---11P.10.000016
ORF1ab/nsp13367T367IaCaaTa11P.1.120.000484
ORF1ab/nsp13367T367IaCaaTa11P.1.140.000048
ORF1ab/nsp13367T367IaCaaTa11P.1.150.000232
ORF1ab/nsp13367T367IaCaaTa11P.1.170.000162
ORF1ab/nsp13367T367IaCaaTa11P.20.000187
ORF1ab/nsp13367T367IaCaaTa11Q.10.000126
ORF1ab/nsp13367T367KaCaaAa11Q.80.000165
ORF1ab/nsp13367T367TacAacG11Q.80.000165
ORF1ab/nsp13367T367IaCaaTa11Q.80.000165
ORF1ab/nsp13367T367IaCaaTa11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.