CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : CodonNum = 336

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13336A336TA5660TnonsynGcaAca519519117242-17244
ORF1ab/nsp13336A336AA5660AsyngcAgcG4254200.98823517242-17244
ORF1ab/nsp13336A336AA5660AsyngcAgcC42530.0070588217242-17244
ORF1ab/nsp13336A336AA5660AsyngcAgcT42520.0047058817242-17244
ORF1ab/nsp13336A336VA5660VnonsyngCagTa313313117242-17244
ORF1ab/nsp13336A336SA5660SnonsynGcaTca4242117242-17244
ORF1ab/nsp13336A336del2A5660del2delgCAg--650.83333317242-17244
ORF1ab/nsp13336A336del2A5660del2delGCAC--610.16666717242-17244
ORF1ab/nsp13336A336delA5660deldelGCA---33117242-17244
ORF1ab/nsp13336A336PA5660PnonsynGcaCca22117242-17244
ORF1ab/nsp13336A336del1A5660del1delGca-ca210.517242-17244
ORF1ab/nsp13336A336LA5660LnonsynGCaTTa210.517242-17244
ORF1ab/nsp13336A336LA5660LnonsynGCaCTa210.517242-17244
ORF1ab/nsp13336A336del1A5660del1delgcAgc-210.517242-17244
ORF1ab/nsp13336A336QA5660QnonsynGCaCAa11117242-17244
ORF1ab/nsp13336A336GA5660GnonsyngCagGa11117242-17244
ORF1ab/nsp13336A336EA5660EnonsyngCagAa11117242-17244

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13336A336TGcaAca519519All0.000099
ORF1ab/nsp13336A336AgcAgcG420425All0.00008
ORF1ab/nsp13336A336AgcAgcC3425All0.000001
ORF1ab/nsp13336A336AgcAgcT2425All0
ORF1ab/nsp13336A336VgCagTa313313All0.00006
ORF1ab/nsp13336A336TGcaAca220220AY.40.000342
ORF1ab/nsp13336A336AgcAgcG205205AY.1060.068654
ORF1ab/nsp13336A336VgCagTa102102AY.40.000159
ORF1ab/nsp13336A336AgcAgcG8787B.1.1.3020.180498
ORF1ab/nsp13336A336VgCagTa4646B.1.20.000405
ORF1ab/nsp13336A336SGcaTca4242All0.000008
ORF1ab/nsp13336A336TGcaAca4040AY.440.000243
ORF1ab/nsp13336A336AgcAgcG3636B.1.1.70.000032
ORF1ab/nsp13336A336TGcaAca2727AY.250.000162
ORF1ab/nsp13336A336TGcaAca2727B.1.617.20.000102
ORF1ab/nsp13336A336AgcAgcG2424AY.430.000106
ORF1ab/nsp13336A336TGcaAca2222B.1.1.70.00002
ORF1ab/nsp13336A336VgCagTa2222B.1.1770.00029
ORF1ab/nsp13336A336VgCagTa2121B.1.1.70.000019
ORF1ab/nsp13336A336VgCagTa2121B.1.617.20.000079
ORF1ab/nsp13336A336VgCagTa1616AY.30.000159
ORF1ab/nsp13336A336AgcAgcG1516B.1.617.20.000056
ORF1ab/nsp13336A336AgcAgcT116B.1.617.20.000004
ORF1ab/nsp13336A336TGcaAca1414B.1.2430.000974
ORF1ab/nsp13336A336TGcaAca1313B.1.1.3170.005352
ORF1ab/nsp13336A336TGcaAca1313B.1.20.000114
ORF1ab/nsp13336A336AgcAgcG1111AY.1030.000068
ORF1ab/nsp13336A336TGcaAca1111AY.200.000428
ORF1ab/nsp13336A336TGcaAca1111AY.340.001067
ORF1ab/nsp13336A336VgCagTa1010AY.250.00006
ORF1ab/nsp13336A336TGcaAca1010B.10.000092
ORF1ab/nsp13336A336VgCagTa99AY.200.00035
ORF1ab/nsp13336A336VgCagTa99B.1.36.270.00687
ORF1ab/nsp13336A336SGcaTca88AY.1140.001849
ORF1ab/nsp13336A336TGcaAca88AY.1200.000297
ORF1ab/nsp13336A336SGcaTca88B.1.1.4810.571429
ORF1ab/nsp13336A336TGcaAca77AD.20.001533
ORF1ab/nsp13336A336TGcaAca77AY.1030.000043
ORF1ab/nsp13336A336SGcaTca77AY.250.000042
ORF1ab/nsp13336A336TGcaAca77AY.30.00007
ORF1ab/nsp13336A336del2gCAg--56All0.000001
ORF1ab/nsp13336A336del2GCAC--16All0
ORF1ab/nsp13336A336TGcaAca66AY.260.00017
ORF1ab/nsp13336A336TGcaAca66P.10.000095
ORF1ab/nsp13336A336AgcAgcG55AY.340.000485
ORF1ab/nsp13336A336SGcaTca55AY.40.000008
ORF1ab/nsp13336A336VgCagTa55B.10.000046
ORF1ab/nsp13336A336SGcaTca44AY.1020.000106
ORF1ab/nsp13336A336TGcaAca44AY.130.000644
ORF1ab/nsp13336A336AgcAgcG44AY.40.000006
ORF1ab/nsp13336A336TGcaAca44AY.50.000083
ORF1ab/nsp13336A336AgcAgcG34B.10.000027
ORF1ab/nsp13336A336AgcAgcC14B.10.000009
ORF1ab/nsp13336A336AgcAgcG44B.1.10.000073
ORF1ab/nsp13336A336VgCagTa44B.1.415.10.030303
ORF1ab/nsp13336A336delGCA---33All0.000001
ORF1ab/nsp13336A336AgcAgcG33AY.1170.000254
ORF1ab/nsp13336A336VgCagTa33AY.230.000209
ORF1ab/nsp13336A336TGcaAca33AY.290.000047
ORF1ab/nsp13336A336TGcaAca33AY.330.0002
ORF1ab/nsp13336A336VgCagTa33AY.4.2.10.000447
ORF1ab/nsp13336A336VgCagTa33AY.430.000013
ORF1ab/nsp13336A336VgCagTa33AY.470.000093
ORF1ab/nsp13336A336TGcaAca33B.1.1.2410.006211
ORF1ab/nsp13336A336AgcAgcG33B.1.177.40.000633
ORF1ab/nsp13336A336TGcaAca33B.1.3670.002377
ORF1ab/nsp13336A336TGcaAca33B.1.4290.000071
ORF1ab/nsp13336A336VgCagTa33C.360.002732
ORF1ab/nsp13336A336AgcAgcG33P.10.000047
ORF1ab/nsp13336A336PGcaCca22All0
ORF1ab/nsp13336A336del1gcAgc-12All0
ORF1ab/nsp13336A336del1Gca-ca12All0
ORF1ab/nsp13336A336LGCaCTa12All0
ORF1ab/nsp13336A336LGCaTTa12All0
ORF1ab/nsp13336A336TGcaAca22AY.1020.000053
ORF1ab/nsp13336A336TGcaAca22AY.1130.000285
ORF1ab/nsp13336A336TGcaAca22AY.1190.000071
ORF1ab/nsp13336A336AgcAgcG12AY.250.000006
ORF1ab/nsp13336A336AgcAgcC12AY.250.000006
ORF1ab/nsp13336A336VgCagTa22AY.290.000032
ORF1ab/nsp13336A336TGcaAca22AY.4.20.000043
ORF1ab/nsp13336A336AgcAgcG22AY.4.20.000043
ORF1ab/nsp13336A336TGcaAca22AY.420.00008
ORF1ab/nsp13336A336VgCagTa22AY.440.000012
ORF1ab/nsp13336A336TGcaAca22AY.46.40.000329
ORF1ab/nsp13336A336AgcAgcG22AY.540.000191
ORF1ab/nsp13336A336TGcaAca22AY.7.10.000225
ORF1ab/nsp13336A336TGcaAca22AY.99.20.000184
ORF1ab/nsp13336A336SGcaTca22B.1.20.000018
ORF1ab/nsp13336A336AgcAgcC12B.1.2580.000067
ORF1ab/nsp13336A336AgcAgcT12B.1.2580.000067
ORF1ab/nsp13336A336VgCagTa22B.1.360.000292
ORF1ab/nsp13336A336VgCagTa22B.1.4290.000047
ORF1ab/nsp13336A336VgCagTa22B.1.5260.000047
ORF1ab/nsp13336A336del2gCAg--22B.1.617.20.000008
ORF1ab/nsp13336A336SGcaTca22P.10.000032
ORF1ab/nsp13336A336GgCagGa110.055556
ORF1ab/nsp13336A336GgCagGa11All0
ORF1ab/nsp13336A336EgCagAa11All0
ORF1ab/nsp13336A336QGCaCAa11All0
ORF1ab/nsp13336A336VgCagTa11AY.1000.000046
ORF1ab/nsp13336A336TGcaAca11AY.1000.000046
ORF1ab/nsp13336A336EgCagAa11AY.1020.000027
ORF1ab/nsp13336A336SGcaTca11AY.1030.000006
ORF1ab/nsp13336A336LGCaCTa11AY.1030.000006
ORF1ab/nsp13336A336VgCagTa11AY.1030.000006
ORF1ab/nsp13336A336AgcAgcG11AY.1100.000113
ORF1ab/nsp13336A336TGcaAca11AY.1110.000183
ORF1ab/nsp13336A336SGcaTca11AY.1130.000142
ORF1ab/nsp13336A336VgCagTa11AY.1170.000085
ORF1ab/nsp13336A336SGcaTca11AY.1190.000035
ORF1ab/nsp13336A336TGcaAca11AY.230.00007
ORF1ab/nsp13336A336TGcaAca11AY.270.000065
ORF1ab/nsp13336A336TGcaAca11AY.3.10.000085
ORF1ab/nsp13336A336TGcaAca11AY.300.000396
ORF1ab/nsp13336A336TGcaAca11AY.350.000233
ORF1ab/nsp13336A336TGcaAca11AY.360.000148
ORF1ab/nsp13336A336AgcAgcG11AY.360.000148
ORF1ab/nsp13336A336TGcaAca11AY.390.000025
ORF1ab/nsp13336A336VgCagTa11AY.390.000025
ORF1ab/nsp13336A336VgCagTa11AY.4.20.000022
ORF1ab/nsp13336A336TGcaAca11AY.4.2.10.000149
ORF1ab/nsp13336A336VgCagTa11AY.420.00004
ORF1ab/nsp13336A336LGCaTTa11AY.440.000006
ORF1ab/nsp13336A336AgcAgcG11AY.440.000006
ORF1ab/nsp13336A336TGcaAca11AY.460.000104
ORF1ab/nsp13336A336VgCagTa11AY.480.000465
ORF1ab/nsp13336A336VgCagTa11AY.50.000021
ORF1ab/nsp13336A336VgCagTa11AY.60.000041
ORF1ab/nsp13336A336TGcaAca11AY.610.000105
ORF1ab/nsp13336A336TGcaAca11AY.690.000187
ORF1ab/nsp13336A336TGcaAca11AY.710.000475
ORF1ab/nsp13336A336AgcAgcG11AY.90.000068
ORF1ab/nsp13336A336del2gCAg--11AY.9.20.000037
ORF1ab/nsp13336A336TGcaAca11AY.9.20.000037
ORF1ab/nsp13336A336AgcAgcG11AY.910.00073
ORF1ab/nsp13336A336VgCagTa11AY.910.00073
ORF1ab/nsp13336A336AgcAgcG11AY.980.000079
ORF1ab/nsp13336A336QGCaCAa11B0.000128
ORF1ab/nsp13336A336VgCagTa11B0.000128
ORF1ab/nsp13336A336PGcaCca11B.10.000009
ORF1ab/nsp13336A336VgCagTa11B.1.10.000018
ORF1ab/nsp13336A336VgCagTa11B.1.1.2140.000055
ORF1ab/nsp13336A336VgCagTa11B.1.1.2200.001859
ORF1ab/nsp13336A336VgCagTa11B.1.1.280.000311
ORF1ab/nsp13336A336TGcaAca11B.1.1.2840.000107
ORF1ab/nsp13336A336TGcaAca11B.1.1.3180.000302
ORF1ab/nsp13336A336del2gCAg--11B.1.1.70.000001
ORF1ab/nsp13336A336del1gcAgc-11B.1.1.70.000001
ORF1ab/nsp13336A336TGcaAca11B.1.1.700.000341
ORF1ab/nsp13336A336AgcAgcG11B.1.1600.000031
ORF1ab/nsp13336A336VgCagTa11B.1.160.160.000929
ORF1ab/nsp13336A336SGcaTca11B.1.1770.000013
ORF1ab/nsp13336A336AgcAgcG11B.1.177.530.002392
ORF1ab/nsp13336A336AgcAgcG11B.1.177.620.001192
ORF1ab/nsp13336A336del2gCAg--11B.1.177.730.000566
ORF1ab/nsp13336A336TGcaAca11B.1.1890.004292
ORF1ab/nsp13336A336AgcAgcG11B.1.2210.000071
ORF1ab/nsp13336A336VgCagTa11B.1.221.40.004167
ORF1ab/nsp13336A336TGcaAca11B.1.258.170.000104
ORF1ab/nsp13336A336VgCagTa11B.1.2820.014925
ORF1ab/nsp13336A336TGcaAca11B.1.2980.002114
ORF1ab/nsp13336A336AgcAgcG11B.1.3510.00003
ORF1ab/nsp13336A336TGcaAca11B.1.3510.00003
ORF1ab/nsp13336A336VgCagTa11B.1.36.160.001425
ORF1ab/nsp13336A336VgCagTa11B.1.4040.001302
ORF1ab/nsp13336A336TGcaAca11B.1.4270.00005
ORF1ab/nsp13336A336TGcaAca11B.1.466.20.000391
ORF1ab/nsp13336A336AgcAgcG11B.1.4700.001404
ORF1ab/nsp13336A336SGcaTca11B.1.4740.001901
ORF1ab/nsp13336A336TGcaAca11B.1.4970.000315
ORF1ab/nsp13336A336TGcaAca11B.1.5260.000024
ORF1ab/nsp13336A336TGcaAca11B.1.5750.000303
ORF1ab/nsp13336A336VgCagTa11B.1.5960.000087
ORF1ab/nsp13336A336SGcaTca11B.1.5960.000087
ORF1ab/nsp13336A336TGcaAca11B.1.617.10.000129
ORF1ab/nsp13336A336del1Gca-ca11B.1.617.20.000004
ORF1ab/nsp13336A336TGcaAca11B.1.6210.000089
ORF1ab/nsp13336A336TGcaAca11B.1.6250.002353
ORF1ab/nsp13336A336TGcaAca11B.1.6370.000073
ORF1ab/nsp13336A336delGCA---11B.340.013699
ORF1ab/nsp13336A336del2GCAC--11B.6.60.000889
ORF1ab/nsp13336A336delGCA---11C.360.000911
ORF1ab/nsp13336A336VgCagTa11P.10.000016
ORF1ab/nsp13336A336delGCA---11P.10.000016
ORF1ab/nsp13336A336VgCagTa11Q.10.000126
ORF1ab/nsp13336A336PGcaCca11Q.30.000145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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