CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : CodonNum = 291

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13291F291LF5615LnonsynttTttG118990.83898317107-17109
ORF1ab/nsp13291F291LF5615LnonsynTttCtt118170.14406817107-17109
ORF1ab/nsp13291F291LF5615LnonsynttTttA11820.016949217107-17109
ORF1ab/nsp13291F291FF5615FsynttTttC7272117107-17109
ORF1ab/nsp13291F291CF5615CnonsyntTttGt69680.98550717107-17109
ORF1ab/nsp13291F291CF5615CnonsyntTTtGC6910.014492817107-17109
ORF1ab/nsp13291F291VF5615VnonsynTttGtt3535117107-17109
ORF1ab/nsp13291F291YF5615YnonsyntTttAt3434117107-17109
ORF1ab/nsp13291F291delF5615deldelTTT---1818117107-17109
ORF1ab/nsp13291F291IF5615InonsynTttAtt77117107-17109
ORF1ab/nsp13291F291SF5615SnonsyntTttCt33117107-17109
ORF1ab/nsp13291F291del1F5615del1delTtt-tt22117107-17109
ORF1ab/nsp13291F291PF5615PnonsynTTtCCt11117107-17109
ORF1ab/nsp13291F291QF5615QnonsynTTTCAA11117107-17109

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13291F291LttTttG99118All0.000019
ORF1ab/nsp13291F291LTttCtt17118All0.000003
ORF1ab/nsp13291F291LttTttA2118All0
ORF1ab/nsp13291F291FttTttC7272All0.000014
ORF1ab/nsp13291F291CtTttGt6869All0.000013
ORF1ab/nsp13291F291CtTTtGC169All0
ORF1ab/nsp13291F291VTttGtt3535All0.000007
ORF1ab/nsp13291F291YtTttAt3434All0.000007
ORF1ab/nsp13291F291LttTttG2629B.1.1.70.000023
ORF1ab/nsp13291F291LTttCtt329B.1.1.70.000003
ORF1ab/nsp13291F291LttTttG2128B.1.1770.000277
ORF1ab/nsp13291F291LTttCtt728B.1.1770.000092
ORF1ab/nsp13291F291YtTttAt2525B.1.5940.78125
ORF1ab/nsp13291F291FttTttC2020Q.10.002527
ORF1ab/nsp13291F291delTTT---1818All0.000003
ORF1ab/nsp13291F291CtTttGt1818B.1.1.70.000016
ORF1ab/nsp13291F291FttTttC1111B.1.1.70.00001
ORF1ab/nsp13291F291VTttGtt1010B.1.1.70.000009
ORF1ab/nsp13291F291VTttGtt99B.1.5250.001018
ORF1ab/nsp13291F291VTttGtt88B.1.4290.000188
ORF1ab/nsp13291F291FttTttC88B.1.617.20.00003
ORF1ab/nsp13291F291ITttAtt77All0.000001
ORF1ab/nsp13291F291CtTttGt77AY.290.00011
ORF1ab/nsp13291F291LttTttG77AY.99.20.000645
ORF1ab/nsp13291F291LttTttG67P.10.000095
ORF1ab/nsp13291F291LTttCtt17P.10.000016
ORF1ab/nsp13291F291FttTttC66AY.1030.000037
ORF1ab/nsp13291F291delTTT---55AY.250.00003
ORF1ab/nsp13291F291CtTttGt55AY.250.00003
ORF1ab/nsp13291F291CtTttGt55AY.30.00005
ORF1ab/nsp13291F291FttTttC55B.10.000046
ORF1ab/nsp13291F291FttTttC44AY.20.001425
ORF1ab/nsp13291F291FttTttC44AY.40.000006
ORF1ab/nsp13291F291LttTttG34AY.440.000018
ORF1ab/nsp13291F291LTttCtt14AY.440.000006
ORF1ab/nsp13291F291ITttAtt44B.10.000037
ORF1ab/nsp13291F291LttTttG44B.1.6210.000354
ORF1ab/nsp13291F291StTttCt33All0.000001
ORF1ab/nsp13291F291LttTttG33AY.50.000062
ORF1ab/nsp13291F291LttTttA23B.10.000018
ORF1ab/nsp13291F291LTttCtt13B.10.000009
ORF1ab/nsp13291F291LttTttG33B.1.10.000054
ORF1ab/nsp13291F291CtTttGt33B.1.1.2140.000166
ORF1ab/nsp13291F291LttTttG33B.1.575.10.007317
ORF1ab/nsp13291F291CtTttGt33B.1.617.20.000011
ORF1ab/nsp13291F291CtTttGt33B.1.6210.000266
ORF1ab/nsp13291F291del1Ttt-tt22All0
ORF1ab/nsp13291F291LTttCtt12AY.250.000006
ORF1ab/nsp13291F291LttTttG12AY.250.000006
ORF1ab/nsp13291F291LttTttG22AY.40.000003
ORF1ab/nsp13291F291delTTT---22AY.40.000003
ORF1ab/nsp13291F291delTTT---22AY.430.000009
ORF1ab/nsp13291F291CtTttGt22AY.46.60.000144
ORF1ab/nsp13291F291YtTttAt22AY.470.000062
ORF1ab/nsp13291F291LttTttG22AY.9.20.000073
ORF1ab/nsp13291F291delTTT---22B.10.000018
ORF1ab/nsp13291F291FttTttC22B.1.1.2160.001781
ORF1ab/nsp13291F291CtTttGt22B.1.1.2220.000408
ORF1ab/nsp13291F291CtTttGt22B.1.1.2840.000215
ORF1ab/nsp13291F291delTTT---22B.1.1.70.000002
ORF1ab/nsp13291F291CtTttGt22B.1.2340.000264
ORF1ab/nsp13291F291LttTttG22B.1.3510.000059
ORF1ab/nsp13291F291YtTttAt22B.1.4460.04
ORF1ab/nsp13291F291FttTttC22P.10.000032
ORF1ab/nsp13291F291PTTtCCt11All0
ORF1ab/nsp13291F291QTTTCAA11All0
ORF1ab/nsp13291F291CtTttGt11AY.1030.000006
ORF1ab/nsp13291F291FttTttC11AY.1170.000085
ORF1ab/nsp13291F291FttTttC11AY.1180.000063
ORF1ab/nsp13291F291LttTttG11AY.200.000039
ORF1ab/nsp13291F291FttTttC11AY.250.000006
ORF1ab/nsp13291F291FttTttC11AY.30.00001
ORF1ab/nsp13291F291LTttCtt11AY.30.00001
ORF1ab/nsp13291F291CtTTtGC11AY.360.000148
ORF1ab/nsp13291F291delTTT---11AY.420.00004
ORF1ab/nsp13291F291CtTttGt11AY.430.000004
ORF1ab/nsp13291F291VTttGtt11AY.440.000006
ORF1ab/nsp13291F291FttTttC11AY.460.000104
ORF1ab/nsp13291F291LttTttG11AY.46.30.000934
ORF1ab/nsp13291F291FttTttC11AY.470.000031
ORF1ab/nsp13291F291VTttGtt11AY.470.000031
ORF1ab/nsp13291F291CtTttGt11AY.470.000031
ORF1ab/nsp13291F291FttTttC11AY.5.40.000277
ORF1ab/nsp13291F291CtTttGt11AY.520.000814
ORF1ab/nsp13291F291LttTttG11AY.530.000288
ORF1ab/nsp13291F291LttTttG11AY.700.000209
ORF1ab/nsp13291F291LttTttG11AY.940.000443
ORF1ab/nsp13291F291delTTT---11AY.990.001049
ORF1ab/nsp13291F291VTttGtt11B0.000128
ORF1ab/nsp13291F291StTttCt11B.10.000009
ORF1ab/nsp13291F291del1Ttt-tt11B.10.000009
ORF1ab/nsp13291F291VTttGtt11B.10.000009
ORF1ab/nsp13291F291CtTttGt11B.10.000009
ORF1ab/nsp13291F291CtTttGt11B.1.10.000018
ORF1ab/nsp13291F291LttTttG11B.1.1.280.000311
ORF1ab/nsp13291F291VTttGtt11B.1.1.2840.000107
ORF1ab/nsp13291F291YtTttAt11B.1.1.3180.000302
ORF1ab/nsp13291F291LttTttG11B.1.1.3180.000302
ORF1ab/nsp13291F291CtTttGt11B.1.1.4340.000349
ORF1ab/nsp13291F291FttTttC11B.1.1.500.000679
ORF1ab/nsp13291F291CtTttGt11B.1.1.5190.00004
ORF1ab/nsp13291F291LttTttG11B.1.1.890.006061
ORF1ab/nsp13291F291CtTttGt11B.1.1600.000031
ORF1ab/nsp13291F291del1Ttt-tt11B.1.1770.000013
ORF1ab/nsp13291F291YtTttAt11B.1.1770.000013
ORF1ab/nsp13291F291ITttAtt11B.1.1770.000013
ORF1ab/nsp13291F291FttTttC11B.1.1770.000013
ORF1ab/nsp13291F291PTTtCCt11B.1.1770.000013
ORF1ab/nsp13291F291StTttCt11B.1.1770.000013
ORF1ab/nsp13291F291LttTttG11B.1.177.100.000878
ORF1ab/nsp13291F291LttTttG11B.1.177.310.011494
ORF1ab/nsp13291F291LTttCtt11B.1.177.750.001041
ORF1ab/nsp13291F291ITttAtt11B.1.20.000009
ORF1ab/nsp13291F291CtTttGt11B.1.20.000009
ORF1ab/nsp13291F291FttTttC11B.1.20.000009
ORF1ab/nsp13291F291YtTttAt11B.1.20.000009
ORF1ab/nsp13291F291ITttAtt11B.1.2340.000132
ORF1ab/nsp13291F291CtTttGt11B.1.2400.000216
ORF1ab/nsp13291F291VTttGtt11B.1.2580.000067
ORF1ab/nsp13291F291VTttGtt11B.1.3110.000275
ORF1ab/nsp13291F291CtTttGt11B.1.4260.001009
ORF1ab/nsp13291F291delTTT---11B.1.4270.00005
ORF1ab/nsp13291F291LttTttG11B.1.5250.000113
ORF1ab/nsp13291F291CtTttGt11B.1.5250.000113
ORF1ab/nsp13291F291LttTttG11B.1.5260.000024
ORF1ab/nsp13291F291LttTttG11B.1.5750.000303
ORF1ab/nsp13291F291LttTttG11B.1.617.20.000004
ORF1ab/nsp13291F291delTTT---11B.1.617.20.000004
ORF1ab/nsp13291F291YtTttAt11B.1.617.20.000004
ORF1ab/nsp13291F291QTTTCAA11B.1.6210.000089
ORF1ab/nsp13291F291LttTttG11B.1.621.10.000506
ORF1ab/nsp13291F291LttTttG11B.1.6230.000536
ORF1ab/nsp13291F291VTttGtt11B.1.6360.006711
ORF1ab/nsp13291F291CtTttGt11B.1.6370.000073
ORF1ab/nsp13291F291CtTttGt11C.230.005814
ORF1ab/nsp13291F291YtTttAt11C.36.30.000567
ORF1ab/nsp13291F291CtTttGt11P.10.000016
ORF1ab/nsp13291F291LTttCtt11Q.10.000126
ORF1ab/nsp13291F291StTttCt11Q.10.000126
ORF1ab/nsp13291F291delTTT---11Q.20.000613

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.