CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : CodonNum = 281

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13281Q281QQ5605QsyncaGcaA19921992117077-17079
ORF1ab/nsp13281Q281RQ5605RnonsyncAgcGg219219117077-17079
ORF1ab/nsp13281Q281HQ5605HnonsyncaGcaT7777117077-17079
ORF1ab/nsp13281Q281XQ5605XnonsynCagTag17140.82352917077-17079
ORF1ab/nsp13281Q281XQ5605XnonsynCaGTaA1730.17647117077-17079
ORF1ab/nsp13281Q281delQ5605deldelCAG---1313117077-17079
ORF1ab/nsp13281Q281LQ5605LnonsyncAgcTg1180.72727317077-17079
ORF1ab/nsp13281Q281LQ5605LnonsynCAGTTA1110.090909117077-17079
ORF1ab/nsp13281Q281LQ5605LnonsyncAGcTA1110.090909117077-17079
ORF1ab/nsp13281Q281LQ5605LnonsynCAgTTg1110.090909117077-17079
ORF1ab/nsp13281Q281PQ5605PnonsyncAgcCg950.55555617077-17079
ORF1ab/nsp13281Q281PQ5605PnonsyncAGcCA940.44444417077-17079
ORF1ab/nsp13281Q281KQ5605KnonsynCagAag760.85714317077-17079
ORF1ab/nsp13281Q281KQ5605KnonsynCaGAaA710.14285717077-17079
ORF1ab/nsp13281Q281EQ5605EnonsynCagGag44117077-17079
ORF1ab/nsp13281Q281del2Q5605del2delCAg--g430.7517077-17079
ORF1ab/nsp13281Q281del1Q5605del1delcaGca-430.7517077-17079
ORF1ab/nsp13281Q281SQ5605SnonsynCAgTCg420.517077-17079
ORF1ab/nsp13281Q281SQ5605SnonsynCAGTCA420.517077-17079
ORF1ab/nsp13281Q281del1Q5605del1delCaGTa-410.2517077-17079
ORF1ab/nsp13281Q281del2Q5605del2delCAG--A410.2517077-17079
ORF1ab/nsp13281Q281IQ5605InonsynCAGATA11117077-17079

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13281Q281QcaGcaA19921992All0.000381
ORF1ab/nsp13281Q281QcaGcaA13291329B.1.1.5190.052776
ORF1ab/nsp13281Q281RcAgcGg219219All0.000042
ORF1ab/nsp13281Q281QcaGcaA192192B.1.1.70.000172
ORF1ab/nsp13281Q281RcAgcGg112112B.1.1.3010.132075
ORF1ab/nsp13281Q281QcaGcaA9696AY.440.000584
ORF1ab/nsp13281Q281HcaGcaT7777All0.000015
ORF1ab/nsp13281Q281QcaGcaA5454B.1.4290.001271
ORF1ab/nsp13281Q281RcAgcGg3232B.1.2340.004222
ORF1ab/nsp13281Q281HcaGcaT2929B.1.6010.878788
ORF1ab/nsp13281Q281RcAgcGg2727B.1.1.70.000024
ORF1ab/nsp13281Q281QcaGcaA2323AY.40.000036
ORF1ab/nsp13281Q281QcaGcaA2323AY.4.20.000499
ORF1ab/nsp13281Q281QcaGcaA2222B.1.617.20.000083
ORF1ab/nsp13281Q281QcaGcaA1818B.10.000165
ORF1ab/nsp13281Q281XCagTag1417All0.000003
ORF1ab/nsp13281Q281XCaGTaA317All0.000001
ORF1ab/nsp13281Q281QcaGcaA1515AY.250.00009
ORF1ab/nsp13281Q281delCAG---1313All0.000002
ORF1ab/nsp13281Q281LcAgcTg811All0.000002
ORF1ab/nsp13281Q281LCAgTTg111All0
ORF1ab/nsp13281Q281LCAGTTA111All0
ORF1ab/nsp13281Q281LcAGcTA111All0
ORF1ab/nsp13281Q281QcaGcaA1111AY.1020.000292
ORF1ab/nsp13281Q281QcaGcaA1111P.10.000173
ORF1ab/nsp13281Q281QcaGcaA1010AY.1000.00046
ORF1ab/nsp13281Q281QcaGcaA1010AY.4.50.001075
ORF1ab/nsp13281Q281QcaGcaA1010B.1.10.000181
ORF1ab/nsp13281Q281QcaGcaA1010B.1.1.4640.014728
ORF1ab/nsp13281Q281QcaGcaA1010B.1.20.000088
ORF1ab/nsp13281Q281QcaGcaA1010B.1.5780.178571
ORF1ab/nsp13281Q281QcaGcaA1010B.1.619.10.006414
ORF1ab/nsp13281Q281PcAgcCg59All0.000001
ORF1ab/nsp13281Q281PcAGcCA49All0.000001
ORF1ab/nsp13281Q281QcaGcaA99AY.1190.000318
ORF1ab/nsp13281Q281QcaGcaA99AY.30.00009
ORF1ab/nsp13281Q281QcaGcaA99AY.39.10.000357
ORF1ab/nsp13281Q281RcAgcGg99B.1.20.000079
ORF1ab/nsp13281Q281HcaGcaT88B.1.20.00007
ORF1ab/nsp13281Q281HcaGcaT88B.1.5260.000188
ORF1ab/nsp13281Q281KCagAag67All0.000001
ORF1ab/nsp13281Q281KCaGAaA17All0
ORF1ab/nsp13281Q281HcaGcaT77B.1.1600.000218
ORF1ab/nsp13281Q281QcaGcaA66AY.1130.000854
ORF1ab/nsp13281Q281QcaGcaA66AY.1210.000812
ORF1ab/nsp13281Q281QcaGcaA66B.1.4270.000303
ORF1ab/nsp13281Q281PcAgcCg350.166667
ORF1ab/nsp13281Q281PcAGcCA250.111111
ORF1ab/nsp13281Q281RcAgcGg55AY.40.000008
ORF1ab/nsp13281Q281QcaGcaA55B.1.160.260.012107
ORF1ab/nsp13281Q281RcAgcGg55B.1.2430.000348
ORF1ab/nsp13281Q281QcaGcaA440.222222
ORF1ab/nsp13281Q281XCaGTaA240.111111
ORF1ab/nsp13281Q281XCagTag240.111111
ORF1ab/nsp13281Q281LCAGTTA140.055556
ORF1ab/nsp13281Q281LcAGcTA140.055556
ORF1ab/nsp13281Q281LCAgTTg140.055556
ORF1ab/nsp13281Q281LcAgcTg140.055556
ORF1ab/nsp13281Q281ECagGag44All0.000001
ORF1ab/nsp13281Q281del1caGca-34All0.000001
ORF1ab/nsp13281Q281del2CAg--g34All0.000001
ORF1ab/nsp13281Q281SCAGTCA24All0
ORF1ab/nsp13281Q281SCAgTCg24All0
ORF1ab/nsp13281Q281del1CaGTa-14All0
ORF1ab/nsp13281Q281del2CAG--A14All0
ORF1ab/nsp13281Q281QcaGcaA44AY.430.000018
ORF1ab/nsp13281Q281HcaGcaT44B0.000511
ORF1ab/nsp13281Q281RcAgcGg44B.10.000037
ORF1ab/nsp13281Q281QcaGcaA33A.2.50.001497
ORF1ab/nsp13281Q281QcaGcaA33AY.260.000085
ORF1ab/nsp13281Q281QcaGcaA33AY.290.000047
ORF1ab/nsp13281Q281del1caGca-23AY.440.000012
ORF1ab/nsp13281Q281del1CaGTa-13AY.440.000006
ORF1ab/nsp13281Q281HcaGcaT33B.10.000027
ORF1ab/nsp13281Q281RcAgcGg33B.1.10.000054
ORF1ab/nsp13281Q281KCagAag33B.1.1.70.000003
ORF1ab/nsp13281Q281LcAgcTg33B.1.1.70.000003
ORF1ab/nsp13281Q281QcaGcaA33B.1.2580.0002
ORF1ab/nsp13281Q281ECagGag33B.1.617.20.000011
ORF1ab/nsp13281Q281SCAgTCg120.055556
ORF1ab/nsp13281Q281SCAGTCA120.055556
ORF1ab/nsp13281Q281RcAgcGg22A.10.000564
ORF1ab/nsp13281Q281QcaGcaA22AY.1030.000012
ORF1ab/nsp13281Q281RcAgcGg22AY.290.000032
ORF1ab/nsp13281Q281QcaGcaA22AY.390.000049
ORF1ab/nsp13281Q281HcaGcaT22AY.40.000003
ORF1ab/nsp13281Q281LcAgcTg22AY.40.000003
ORF1ab/nsp13281Q281QcaGcaA22AY.750.000112
ORF1ab/nsp13281Q281XCagTag22B.1.10.000036
ORF1ab/nsp13281Q281QcaGcaA22B.1.1.1530.002191
ORF1ab/nsp13281Q281QcaGcaA22B.1.1.2140.000111
ORF1ab/nsp13281Q281QcaGcaA22B.1.1.2910.001485
ORF1ab/nsp13281Q281RcAgcGg22B.1.1.3180.000604
ORF1ab/nsp13281Q281del2CAg--g22B.1.1.70.000002
ORF1ab/nsp13281Q281delCAG---22B.1.1.70.000002
ORF1ab/nsp13281Q281RcAgcGg22B.1.1390.001466
ORF1ab/nsp13281Q281QcaGcaA22B.1.1770.000026
ORF1ab/nsp13281Q281QcaGcaA22B.1.2210.000142
ORF1ab/nsp13281Q281KCaGAaA12B.1.2210.000071
ORF1ab/nsp13281Q281SCAgTCg12B.1.2210.000071
ORF1ab/nsp13281Q281SCAGTCA12B.1.2210.000071
ORF1ab/nsp13281Q281KCagAag12B.1.2210.000071
ORF1ab/nsp13281Q281PcAGcCA12B.1.2210.000071
ORF1ab/nsp13281Q281XCaGTaA12B.1.2210.000071
ORF1ab/nsp13281Q281XCagTag12B.1.2210.000071
ORF1ab/nsp13281Q281PcAgcCg12B.1.2210.000071
ORF1ab/nsp13281Q281HcaGcaT22B.1.2430.000139
ORF1ab/nsp13281Q281QcaGcaA22B.1.5750.000607
ORF1ab/nsp13281Q281RcAgcGg22B.1.617.20.000008
ORF1ab/nsp13281Q281QcaGcaA22C.370.000232
ORF1ab/nsp13281Q281HcaGcaT11A0.000387
ORF1ab/nsp13281Q281PcAgcCg11A0.000387
ORF1ab/nsp13281Q281ICAGATA11All0
ORF1ab/nsp13281Q281QcaGcaA11AY.10.000396
ORF1ab/nsp13281Q281QcaGcaA11AY.1010.00049
ORF1ab/nsp13281Q281RcAgcGg11AY.1020.000027
ORF1ab/nsp13281Q281RcAgcGg11AY.1030.000006
ORF1ab/nsp13281Q281QcaGcaA11AY.1180.000063
ORF1ab/nsp13281Q281RcAgcGg11AY.1180.000063
ORF1ab/nsp13281Q281HcaGcaT11AY.1210.000135
ORF1ab/nsp13281Q281QcaGcaA11AY.140.000088
ORF1ab/nsp13281Q281del2CAG--A11AY.200.000039
ORF1ab/nsp13281Q281HcaGcaT11AY.250.000006
ORF1ab/nsp13281Q281HcaGcaT11AY.30.00001
ORF1ab/nsp13281Q281QcaGcaA11AY.340.000097
ORF1ab/nsp13281Q281XCagTag11AY.390.000025
ORF1ab/nsp13281Q281delCAG---11AY.420.00004
ORF1ab/nsp13281Q281KCagAag11AY.430.000004
ORF1ab/nsp13281Q281HcaGcaT11AY.430.000004
ORF1ab/nsp13281Q281delCAG---11AY.430.000004
ORF1ab/nsp13281Q281RcAgcGg11AY.440.000006
ORF1ab/nsp13281Q281ICAGATA11AY.440.000006
ORF1ab/nsp13281Q281PcAGcCA11AY.46.20.000635
ORF1ab/nsp13281Q281QcaGcaA11AY.46.60.000072
ORF1ab/nsp13281Q281QcaGcaA11AY.50.000021
ORF1ab/nsp13281Q281QcaGcaA11AY.5.30.000337
ORF1ab/nsp13281Q281QcaGcaA11AY.580.000907
ORF1ab/nsp13281Q281QcaGcaA11AY.610.000105
ORF1ab/nsp13281Q281QcaGcaA11AY.670.000464
ORF1ab/nsp13281Q281delCAG---11AY.750.000056
ORF1ab/nsp13281Q281XCagTag11AY.750.000056
ORF1ab/nsp13281Q281QcaGcaA11AY.9.20.000037
ORF1ab/nsp13281Q281del2CAg--g11AY.98.10.000048
ORF1ab/nsp13281Q281HcaGcaT11AY.98.10.000048
ORF1ab/nsp13281Q281delCAG---11AY.990.001049
ORF1ab/nsp13281Q281delCAG---11B.10.000009
ORF1ab/nsp13281Q281XCagTag11B.1.1.10.000327
ORF1ab/nsp13281Q281QcaGcaA11B.1.1.1610.003534
ORF1ab/nsp13281Q281RcAgcGg11B.1.1.1890.001513
ORF1ab/nsp13281Q281HcaGcaT11B.1.1.2310.003096
ORF1ab/nsp13281Q281HcaGcaT11B.1.1.2320.001815
ORF1ab/nsp13281Q281XCagTag11B.1.1.250.000569
ORF1ab/nsp13281Q281QcaGcaA11B.1.1.2630.001558
ORF1ab/nsp13281Q281QcaGcaA11B.1.1.2840.000107
ORF1ab/nsp13281Q281RcAgcGg11B.1.1.3060.000438
ORF1ab/nsp13281Q281QcaGcaA11B.1.1.3720.000689
ORF1ab/nsp13281Q281RcAgcGg11B.1.1.3770.001381
ORF1ab/nsp13281Q281QcaGcaA11B.1.1.4200.001006
ORF1ab/nsp13281Q281ECagGag11B.1.1.4320.001266
ORF1ab/nsp13281Q281del1caGca-11B.1.1.70.000001
ORF1ab/nsp13281Q281QcaGcaA11B.1.1600.000031
ORF1ab/nsp13281Q281RcAgcGg11B.1.1770.000013
ORF1ab/nsp13281Q281LcAgcTg11B.1.1770.000013
ORF1ab/nsp13281Q281delCAG---11B.1.1770.000013
ORF1ab/nsp13281Q281delCAG---11B.1.177.150.000631
ORF1ab/nsp13281Q281HcaGcaT11B.1.177.210.000076
ORF1ab/nsp13281Q281QcaGcaA11B.1.177.570.000281
ORF1ab/nsp13281Q281QcaGcaA11B.1.177.650.000665
ORF1ab/nsp13281Q281QcaGcaA11B.1.177.70.000165
ORF1ab/nsp13281Q281RcAgcGg11B.1.177.810.000189
ORF1ab/nsp13281Q281QcaGcaA11B.1.177.860.000183
ORF1ab/nsp13281Q281QcaGcaA11B.1.177.870.000728
ORF1ab/nsp13281Q281delCAG---11B.1.20.000009
ORF1ab/nsp13281Q281XCagTag11B.1.20.000009
ORF1ab/nsp13281Q281QcaGcaA11B.1.2220.001692
ORF1ab/nsp13281Q281RcAgcGg11B.1.2320.000537
ORF1ab/nsp13281Q281QcaGcaA11B.1.2430.00007
ORF1ab/nsp13281Q281QcaGcaA11B.1.258.170.000104
ORF1ab/nsp13281Q281RcAgcGg11B.1.3510.00003
ORF1ab/nsp13281Q281QcaGcaA11B.1.3510.00003
ORF1ab/nsp13281Q281QcaGcaA11B.1.360.000146
ORF1ab/nsp13281Q281QcaGcaA11B.1.36.100.004785
ORF1ab/nsp13281Q281RcAgcGg11B.1.36.390.002217
ORF1ab/nsp13281Q281HcaGcaT11B.1.3690.000285
ORF1ab/nsp13281Q281QcaGcaA11B.1.4000.000429
ORF1ab/nsp13281Q281delCAG---11B.1.4270.00005
ORF1ab/nsp13281Q281HcaGcaT11B.1.5250.000113
ORF1ab/nsp13281Q281KCagAag11B.1.5250.000113
ORF1ab/nsp13281Q281QcaGcaA11B.1.5260.000024
ORF1ab/nsp13281Q281XCagTag11B.1.5960.000087
ORF1ab/nsp13281Q281HcaGcaT11B.1.617.10.000129
ORF1ab/nsp13281Q281HcaGcaT11B.1.617.20.000004
ORF1ab/nsp13281Q281LcAgcTg11B.1.617.20.000004
ORF1ab/nsp13281Q281XCagTag11B.1.617.20.000004
ORF1ab/nsp13281Q281delCAG---11B.1.617.20.000004
ORF1ab/nsp13281Q281QcaGcaA11B.1.6210.000089
ORF1ab/nsp13281Q281XCagTag11B.1.780.008547
ORF1ab/nsp13281Q281QcaGcaA11B.30.000831
ORF1ab/nsp13281Q281delCAG---11B.340.013699
ORF1ab/nsp13281Q281QcaGcaA11B.400.000364
ORF1ab/nsp13281Q281HcaGcaT11B.6.30.026316
ORF1ab/nsp13281Q281QcaGcaA11D.20.000075
ORF1ab/nsp13281Q281QcaGcaA11N.30.005814
ORF1ab/nsp13281Q281XCagTag11P.10.000016
ORF1ab/nsp13281Q281QcaGcaA11P.1.140.000048
ORF1ab/nsp13281Q281QcaGcaA11Q.10.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.