CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : CodonNum = 268

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13268N268NN5592NsynaaTaaC322174322174117038-17040
ORF1ab/nsp13268N268SN5592SnonsynaAtaGt3973920.98740617038-17040
ORF1ab/nsp13268N268SN5592SnonsynaATaGC39750.012594517038-17040
ORF1ab/nsp13268N268HN5592HnonsynAatCat231231117038-17040
ORF1ab/nsp13268N268KN5592KnonsynaaTaaA1701140.67058817038-17040
ORF1ab/nsp13268N268KN5592KnonsynaaTaaG170560.32941217038-17040
ORF1ab/nsp13268N268DN5592DnonsynAaTGaC86710.82558117038-17040
ORF1ab/nsp13268N268DN5592DnonsynAatGat86150.17441917038-17040
ORF1ab/nsp13268N268TN5592TnonsynaAtaCt7575117038-17040
ORF1ab/nsp13268N268delN5592deldelAAT---1515117038-17040
ORF1ab/nsp13268N268IN5592InonsynaAtaTt1313117038-17040
ORF1ab/nsp13268N268del1N5592del1delAat-at530.617038-17040
ORF1ab/nsp13268N268del1N5592del1delaaTaa-520.417038-17040
ORF1ab/nsp13268N268CN5592CnonsynAAtTGt33117038-17040
ORF1ab/nsp13268N268LN5592LnonsynAAtCTt33117038-17040
ORF1ab/nsp13268N268YN5592YnonsynAatTat33117038-17040
ORF1ab/nsp13268N268del2N5592del2delAAt--t11117038-17040
ORF1ab/nsp13268N268PN5592PnonsynAAtCCt11117038-17040
ORF1ab/nsp13268N268VN5592VnonsynAAtGTt11117038-17040
ORF1ab/nsp13268N268FN5592FnonsynAAtTTt11117038-17040

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13268N268NaaTaaC322174322174All0.06162
ORF1ab/nsp13268N268NaaTaaC258834258834AY.40.402855
ORF1ab/nsp13268N268NaaTaaC4609646096AY.4.20.999761
ORF1ab/nsp13268N268NaaTaaC65656565AY.4.2.10.978099
ORF1ab/nsp13268N268NaaTaaC56765676B.1.617.20.021372
ORF1ab/nsp13268N268NaaTaaC13541354AY.4.10.998525
ORF1ab/nsp13268N268NaaTaaC966966AY.430.00428
ORF1ab/nsp13268N268NaaTaaC627627AY.420.025224
ORF1ab/nsp13268N268NaaTaaC438438AY.90.029607
ORF1ab/nsp13268N268SaAtaGt392397All0.000075
ORF1ab/nsp13268N268SaATaGC5397All0.000001
ORF1ab/nsp13268N268NaaTaaC300300B.1.4330.958466
ORF1ab/nsp13268N268HAatCat231231All0.000044
ORF1ab/nsp13268N268NaaTaaC217217AY.410.063786
ORF1ab/nsp13268N268HAatCat187187B.1.1.70.000167
ORF1ab/nsp13268N268NaaTaaC175175AY.390.004325
ORF1ab/nsp13268N268KaaTaaA114170All0.000022
ORF1ab/nsp13268N268KaaTaaG56170All0.000011
ORF1ab/nsp13268N268SaAtaGt165165B.1.1.70.000148
ORF1ab/nsp13268N268NaaTaaC105105AY.4.50.011287
ORF1ab/nsp13268N268KaaTaaA104104AY.420.004184
ORF1ab/nsp13268N268DAaTGaC7186All0.000014
ORF1ab/nsp13268N268DAatGat1586All0.000003
ORF1ab/nsp13268N268SaAtaGt7676AY.1190.002683
ORF1ab/nsp13268N268TaAtaCt7575All0.000014
ORF1ab/nsp13268N268NaaTaaC7171B.1.2580.004725
ORF1ab/nsp13268N268DAaTGaC6566AY.40.000101
ORF1ab/nsp13268N268DAatGat166AY.40.000002
ORF1ab/nsp13268N268NaaTaaC6161B.1.258.240.655914
ORF1ab/nsp13268N268NaaTaaC5252AY.46.60.003755
ORF1ab/nsp13268N268KaaTaaG4444B.1.1.70.000039
ORF1ab/nsp13268N268NaaTaaC3838AY.1200.001413
ORF1ab/nsp13268N268NaaTaaC3333AY.1020.000875
ORF1ab/nsp13268N268NaaTaaC3030AY.840.013123
ORF1ab/nsp13268N268NaaTaaC2727AY.50.000558
ORF1ab/nsp13268N268TaAtaCt2626B.1.1.70.000023
ORF1ab/nsp13268N268NaaTaaC2424AY.4.30.020202
ORF1ab/nsp13268N268TaAtaCt2020AY.260.000566
ORF1ab/nsp13268N268SaAtaGt1919AY.250.000114
ORF1ab/nsp13268N268SaAtaGt1819B.10.000165
ORF1ab/nsp13268N268SaATaGC119B.10.000009
ORF1ab/nsp13268N268NaaTaaC1818AY.1030.000112
ORF1ab/nsp13268N268NaaTaaC1717AY.330.001135
ORF1ab/nsp13268N268NaaTaaC1717AY.440.000103
ORF1ab/nsp13268N268NaaTaaC1717AY.460.001769
ORF1ab/nsp13268N268NaaTaaC1616AY.980.001264
ORF1ab/nsp13268N268delAAT---1515All0.000003
ORF1ab/nsp13268N268NaaTaaC1515AY.890.073529
ORF1ab/nsp13268N268SaAtaGt1515B.1.20.000132
ORF1ab/nsp13268N268IaAtaTt1313All0.000002
ORF1ab/nsp13268N268NaaTaaC1313AY.1170.001099
ORF1ab/nsp13268N268NaaTaaC1313AY.230.000907
ORF1ab/nsp13268N268NaaTaaC1313AY.450.001582
ORF1ab/nsp13268N268NaaTaaC1313AY.910.009496
ORF1ab/nsp13268N268NaaTaaC1313B.10.000119
ORF1ab/nsp13268N268NaaTaaC1212AY.5.30.004049
ORF1ab/nsp13268N268NaaTaaC1212AY.520.009772
ORF1ab/nsp13268N268NaaTaaC1212AY.540.001144
ORF1ab/nsp13268N268NaaTaaC1212AY.60.000494
ORF1ab/nsp13268N268NaaTaaC1212AY.990.012592
ORF1ab/nsp13268N268SaAtaGt1212B.1.1110.014101
ORF1ab/nsp13268N268HAatCat1212B.1.5260.000282
ORF1ab/nsp13268N268NaaTaaC1111AY.320.005857
ORF1ab/nsp13268N268HAatCat1010AY.330.000668
ORF1ab/nsp13268N268NaaTaaC1010AY.340.00097
ORF1ab/nsp13268N268NaaTaaC1010AY.46.10.010267
ORF1ab/nsp13268N268NaaTaaC1010AY.46.20.006353
ORF1ab/nsp13268N268HAatCat99A.2.50.004491
ORF1ab/nsp13268N268NaaTaaC99AY.130.001449
ORF1ab/nsp13268N268NaaTaaC99AY.590.004767
ORF1ab/nsp13268N268SaAtaGt99B.1.360.001313
ORF1ab/nsp13268N268KaaTaaA88AY.40.000012
ORF1ab/nsp13268N268NaaTaaC88AY.780.012327
ORF1ab/nsp13268N268DAaTGaC68B.1.617.20.000023
ORF1ab/nsp13268N268DAatGat28B.1.617.20.000008
ORF1ab/nsp13268N268NaaTaaC77B.1.1.70.000006
ORF1ab/nsp13268N268SaAtaGt77B.1.617.20.000026
ORF1ab/nsp13268N268NaaTaaC66AY.1190.000212
ORF1ab/nsp13268N268TaAtaCt66AY.40.000009
ORF1ab/nsp13268N268NaaTaaC66AY.4.40.002455
ORF1ab/nsp13268N268KaaTaaG66AY.75.10.001082
ORF1ab/nsp13268N268NaaTaaC66AY.75.10.001082
ORF1ab/nsp13268N268del1Aat-at35All0.000001
ORF1ab/nsp13268N268del1aaTaa-25All0
ORF1ab/nsp13268N268NaaTaaC55AY.1080.005513
ORF1ab/nsp13268N268NaaTaaC55AY.1090.003698
ORF1ab/nsp13268N268NaaTaaC55AY.1210.000677
ORF1ab/nsp13268N268SaAtaGt55AY.260.000142
ORF1ab/nsp13268N268SaAtaGt45AY.40.000006
ORF1ab/nsp13268N268SaATaGC15AY.40.000002
ORF1ab/nsp13268N268NaaTaaC55AY.800.005643
ORF1ab/nsp13268N268NaaTaaC55AY.880.004421
ORF1ab/nsp13268N268NaaTaaC55AY.920.001436
ORF1ab/nsp13268N268SaAtaGt55B.1.1600.000156
ORF1ab/nsp13268N268NaaTaaC55B.1.177.810.000947
ORF1ab/nsp13268N268delAAT---440.222222
ORF1ab/nsp13268N268NaaTaaC44AY.1050.002572
ORF1ab/nsp13268N268NaaTaaC44AY.1060.00134
ORF1ab/nsp13268N268NaaTaaC44AY.250.000024
ORF1ab/nsp13268N268NaaTaaC44AY.360.000593
ORF1ab/nsp13268N268HAatCat44AY.440.000024
ORF1ab/nsp13268N268NaaTaaC44AY.470.000124
ORF1ab/nsp13268N268NaaTaaC44AY.5.40.001107
ORF1ab/nsp13268N268NaaTaaC44AY.530.00115
ORF1ab/nsp13268N268NaaTaaC44AY.770.00451
ORF1ab/nsp13268N268NaaTaaC44AY.820.005427
ORF1ab/nsp13268N268NaaTaaC44AY.950.003044
ORF1ab/nsp13268N268NaaTaaC44AY.98.10.000194
ORF1ab/nsp13268N268del1Aat-at24B.1.1.70.000002
ORF1ab/nsp13268N268del1aaTaa-24B.1.1.70.000002
ORF1ab/nsp13268N268TaAtaCt44B.1.1490.013699
ORF1ab/nsp13268N268SaAtaGt44B.1.5550.088889
ORF1ab/nsp13268N268SaAtaGt44Q.80.00066
ORF1ab/nsp13268N268YAatTat33All0.000001
ORF1ab/nsp13268N268CAAtTGt33All0.000001
ORF1ab/nsp13268N268LAAtCTt33All0.000001
ORF1ab/nsp13268N268NaaTaaC33AY.140.000264
ORF1ab/nsp13268N268NaaTaaC33AY.160.001139
ORF1ab/nsp13268N268NaaTaaC33AY.34.10.00153
ORF1ab/nsp13268N268SaAtaGt33AY.450.000365
ORF1ab/nsp13268N268NaaTaaC33AY.46.40.000494
ORF1ab/nsp13268N268NaaTaaC33AY.560.004815
ORF1ab/nsp13268N268NaaTaaC33AY.750.000168
ORF1ab/nsp13268N268IaAtaTt33B.10.000027
ORF1ab/nsp13268N268TaAtaCt33B.10.000027
ORF1ab/nsp13268N268delAAT---33B.1.1.70.000003
ORF1ab/nsp13268N268SaAtaGt33B.1.760.034091
ORF1ab/nsp13268N268TaAtaCt220.111111
ORF1ab/nsp13268N268LAAtCTt220.111111
ORF1ab/nsp13268N268SaAtaGt22AU.30.004219
ORF1ab/nsp13268N268SaAtaGt22AY.1000.000092
ORF1ab/nsp13268N268DAatGat22AY.1000.000092
ORF1ab/nsp13268N268NaaTaaC22AY.1040.003968
ORF1ab/nsp13268N268SaAtaGt22AY.1180.000125
ORF1ab/nsp13268N268NaaTaaC22AY.120.000632
ORF1ab/nsp13268N268TaAtaCt22AY.1200.000074
ORF1ab/nsp13268N268NaaTaaC22AY.120.10.000642
ORF1ab/nsp13268N268SaAtaGt22AY.1210.000271
ORF1ab/nsp13268N268NaaTaaC22AY.190.002281
ORF1ab/nsp13268N268SaAtaGt12AY.340.000097
ORF1ab/nsp13268N268SaATaGC12AY.340.000097
ORF1ab/nsp13268N268SaAtaGt22AY.390.000049
ORF1ab/nsp13268N268SaATaGC22AY.4.20.000043
ORF1ab/nsp13268N268SaAtaGt22AY.4.2.10.000298
ORF1ab/nsp13268N268KaaTaaG22AY.4.40.000818
ORF1ab/nsp13268N268NaaTaaC22AY.400.001929
ORF1ab/nsp13268N268SaAtaGt22AY.440.000012
ORF1ab/nsp13268N268TaAtaCt22AY.460.000208
ORF1ab/nsp13268N268SaAtaGt22AY.460.000208
ORF1ab/nsp13268N268NaaTaaC22AY.580.001815
ORF1ab/nsp13268N268SaAtaGt22AY.690.000373
ORF1ab/nsp13268N268NaaTaaC22AY.730.001331
ORF1ab/nsp13268N268NaaTaaC22AY.810.003984
ORF1ab/nsp13268N268NaaTaaC22AY.860.00166
ORF1ab/nsp13268N268NaaTaaC22AY.99.10.003106
ORF1ab/nsp13268N268SaAtaGt22AY.99.20.000184
ORF1ab/nsp13268N268NaaTaaC22B.1.10.000036
ORF1ab/nsp13268N268NaaTaaC22B.1.1.2160.001781
ORF1ab/nsp13268N268KaaTaaG22B.1.1.3180.000604
ORF1ab/nsp13268N268IaAtaTt22B.1.1.70.000002
ORF1ab/nsp13268N268IaAtaTt22B.1.20.000018
ORF1ab/nsp13268N268HAatCat22B.1.360.000292
ORF1ab/nsp13268N268NaaTaaC22B.1.360.000292
ORF1ab/nsp13268N268SaAtaGt22B.1.3660.009756
ORF1ab/nsp13268N268NaaTaaC22B.1.5950.000522
ORF1ab/nsp13268N268NaaTaaC22B.1.6120.005305
ORF1ab/nsp13268N268NaaTaaC110.055556
ORF1ab/nsp13268N268FAAtTTt11All0
ORF1ab/nsp13268N268del2AAt--t11All0
ORF1ab/nsp13268N268VAAtGTt11All0
ORF1ab/nsp13268N268PAAtCCt11All0
ORF1ab/nsp13268N268NaaTaaC11AY.100.00053
ORF1ab/nsp13268N268NaaTaaC11AY.1000.000046
ORF1ab/nsp13268N268TaAtaCt11AY.1000.000046
ORF1ab/nsp13268N268NaaTaaC11AY.1010.00049
ORF1ab/nsp13268N268DAatGat11AY.1030.000006
ORF1ab/nsp13268N268KaaTaaG11AY.1030.000006
ORF1ab/nsp13268N268SaAtaGt11AY.1030.000006
ORF1ab/nsp13268N268HAatCat11AY.1030.000006
ORF1ab/nsp13268N268delAAT---11AY.1080.001103
ORF1ab/nsp13268N268NaaTaaC11AY.110.001339
ORF1ab/nsp13268N268NaaTaaC11AY.1100.000113
ORF1ab/nsp13268N268NaaTaaC11AY.1110.000183
ORF1ab/nsp13268N268YAatTat11AY.1130.000142
ORF1ab/nsp13268N268NaaTaaC11AY.1130.000142
ORF1ab/nsp13268N268NaaTaaC11AY.116.10.000311
ORF1ab/nsp13268N268NaaTaaC11AY.1180.000063
ORF1ab/nsp13268N268SaAtaGt11AY.1200.000037
ORF1ab/nsp13268N268NaaTaaC11AY.120.2.10.000498
ORF1ab/nsp13268N268SaAtaGt11AY.200.000039
ORF1ab/nsp13268N268SaAtaGt11AY.23.10.000417
ORF1ab/nsp13268N268FAAtTTt11AY.240.000431
ORF1ab/nsp13268N268HAatCat11AY.250.000006
ORF1ab/nsp13268N268DAatGat11AY.260.000028
ORF1ab/nsp13268N268SaAtaGt11AY.290.000016
ORF1ab/nsp13268N268NaaTaaC11AY.29.10.000221
ORF1ab/nsp13268N268SaAtaGt11AY.30.00001
ORF1ab/nsp13268N268DAatGat11AY.30.00001
ORF1ab/nsp13268N268SaAtaGt11AY.330.000067
ORF1ab/nsp13268N268delAAT---11AY.330.000067
ORF1ab/nsp13268N268NaaTaaC11AY.350.000233
ORF1ab/nsp13268N268DAatGat11AY.390.000025
ORF1ab/nsp13268N268HAatCat11AY.390.000025
ORF1ab/nsp13268N268SaAtaGt11AY.39.10.00004
ORF1ab/nsp13268N268TaAtaCt11AY.4.50.000107
ORF1ab/nsp13268N268TaAtaCt11AY.430.000004
ORF1ab/nsp13268N268delAAT---11AY.430.000004
ORF1ab/nsp13268N268DAatGat11AY.430.000004
ORF1ab/nsp13268N268CAAtTGt11AY.440.000006
ORF1ab/nsp13268N268DAatGat11AY.46.40.000165
ORF1ab/nsp13268N268NaaTaaC11AY.46.50.000198
ORF1ab/nsp13268N268SaAtaGt11AY.470.000031
ORF1ab/nsp13268N268DAatGat11AY.470.000031
ORF1ab/nsp13268N268NaaTaaC11AY.490.003195
ORF1ab/nsp13268N268SaAtaGt11AY.50.000021
ORF1ab/nsp13268N268HAatCat11AY.5.40.000277
ORF1ab/nsp13268N268NaaTaaC11AY.620.000436
ORF1ab/nsp13268N268NaaTaaC11AY.640.000595
ORF1ab/nsp13268N268NaaTaaC11AY.660.00107
ORF1ab/nsp13268N268CAAtTGt11AY.670.000464
ORF1ab/nsp13268N268NaaTaaC11AY.680.000274
ORF1ab/nsp13268N268NaaTaaC11AY.690.000187
ORF1ab/nsp13268N268SaAtaGt11AY.7.10.000113
ORF1ab/nsp13268N268IaAtaTt11AY.700.000209
ORF1ab/nsp13268N268NaaTaaC11AY.710.000475
ORF1ab/nsp13268N268CAAtTGt11AY.750.000056
ORF1ab/nsp13268N268NaaTaaC11AY.790.001211
ORF1ab/nsp13268N268NaaTaaC11AY.850.000427
ORF1ab/nsp13268N268NaaTaaC11AY.870.000833
ORF1ab/nsp13268N268NaaTaaC11AY.9.20.000037
ORF1ab/nsp13268N268NaaTaaC11AY.930.000273
ORF1ab/nsp13268N268delAAT---11AY.990.001049
ORF1ab/nsp13268N268del1Aat-at11B.10.000009
ORF1ab/nsp13268N268HAatCat11B.10.000009
ORF1ab/nsp13268N268delAAT---11B.1.10.000018
ORF1ab/nsp13268N268SaAtaGt11B.1.10.000018
ORF1ab/nsp13268N268KaaTaaA11B.1.1.2050.003717
ORF1ab/nsp13268N268HAatCat11B.1.1.250.000569
ORF1ab/nsp13268N268NaaTaaC11B.1.1.2840.000107
ORF1ab/nsp13268N268NaaTaaC11B.1.1.2940.001266
ORF1ab/nsp13268N268SaAtaGt11B.1.1.3180.000302
ORF1ab/nsp13268N268SaAtaGt11B.1.1.3260.001761
ORF1ab/nsp13268N268SaAtaGt11B.1.1.5190.00004
ORF1ab/nsp13268N268SaAtaGt11B.1.1.5260.003546
ORF1ab/nsp13268N268DAatGat11B.1.1.70.000001
ORF1ab/nsp13268N268YAatTat11B.1.1.70.000001
ORF1ab/nsp13268N268PAAtCCt11B.1.1.70.000001
ORF1ab/nsp13268N268VAAtGTt11B.1.1.70.000001
ORF1ab/nsp13268N268NaaTaaC11B.1.110.30.000718
ORF1ab/nsp13268N268DAatGat11B.1.1190.010526
ORF1ab/nsp13268N268NaaTaaC11B.1.1600.000031
ORF1ab/nsp13268N268NaaTaaC11B.1.1770.000013
ORF1ab/nsp13268N268delAAT---11B.1.177.150.000631
ORF1ab/nsp13268N268IaAtaTt11B.1.177.650.000665
ORF1ab/nsp13268N268del2AAt--t11B.1.177.70.000165
ORF1ab/nsp13268N268TaAtaCt11B.1.20.000009
ORF1ab/nsp13268N268NaaTaaC11B.1.20.000009
ORF1ab/nsp13268N268LAAtCTt11B.1.20.000009
ORF1ab/nsp13268N268YAatTat11B.1.214.20.0006
ORF1ab/nsp13268N268TaAtaCt11B.1.2210.000071
ORF1ab/nsp13268N268KaaTaaG11B.1.2430.00007
ORF1ab/nsp13268N268NaaTaaC11B.1.258.110.000396
ORF1ab/nsp13268N268NaaTaaC11B.1.3110.000275
ORF1ab/nsp13268N268TaAtaCt11B.1.3200.001245
ORF1ab/nsp13268N268TaAtaCt11B.1.3360.002439
ORF1ab/nsp13268N268IaAtaTt11B.1.36.100.004785
ORF1ab/nsp13268N268NaaTaaC11B.1.3670.000792
ORF1ab/nsp13268N268TaAtaCt11B.1.4270.00005
ORF1ab/nsp13268N268SaAtaGt11B.1.4270.00005
ORF1ab/nsp13268N268delAAT---11B.1.4270.00005
ORF1ab/nsp13268N268DAatGat11B.1.4290.000024
ORF1ab/nsp13268N268KaaTaaA11B.1.4330.003195
ORF1ab/nsp13268N268NaaTaaC11B.1.438.10.000107
ORF1ab/nsp13268N268TaAtaCt11B.1.4560.003268
ORF1ab/nsp13268N268SaAtaGt11B.1.5960.000087
ORF1ab/nsp13268N268IaAtaTt11B.1.5960.000087
ORF1ab/nsp13268N268TaAtaCt11B.1.5960.000087
ORF1ab/nsp13268N268NaaTaaC11B.1.5960.000087
ORF1ab/nsp13268N268IaAtaTt11B.1.617.20.000004
ORF1ab/nsp13268N268delAAT---11B.1.617.20.000004
ORF1ab/nsp13268N268HAatCat11B.1.617.20.000004
ORF1ab/nsp13268N268NaaTaaC11B.1.6280.000352
ORF1ab/nsp13268N268NaaTaaC11B.400.000364
ORF1ab/nsp13268N268NaaTaaC11B.550.00295
ORF1ab/nsp13268N268IaAtaTt11D.20.000075
ORF1ab/nsp13268N268NaaTaaC11P.10.000016
ORF1ab/nsp13268N268SaAtaGt11P.10.000016
ORF1ab/nsp13268N268SaAtaGt11P.1.150.000232

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.