CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : CodonNum = 154

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13154V154LV5478LnonsynGtaTta120111980.99750216696-16698
ORF1ab/nsp13154V154LV5478LnonsynGtaCta120130.0024979216696-16698
ORF1ab/nsp13154V154VV5478VsyngtAgtG1741620.93103516696-16698
ORF1ab/nsp13154V154VV5478VsyngtAgtT17470.040229916696-16698
ORF1ab/nsp13154V154VV5478VsyngtAgtC17450.028735616696-16698
ORF1ab/nsp13154V154AV5478AnonsyngTagCa144144116696-16698
ORF1ab/nsp13154V154delV5478deldelGTA---9696116696-16698
ORF1ab/nsp13154V154IV5478InonsynGtaAta56540.96428616696-16698
ORF1ab/nsp13154V154IV5478InonsynGtAAtT5620.035714316696-16698
ORF1ab/nsp13154V154GV5478GnonsyngTagGa640.66666716696-16698
ORF1ab/nsp13154V154GV5478GnonsyngTAgGC620.33333316696-16698
ORF1ab/nsp13154V154del1V5478del1delGta-ta44116696-16698
ORF1ab/nsp13154V154SV5478SnonsynGTaTCa22116696-16698
ORF1ab/nsp13154V154EV5478EnonsyngTagAa22116696-16698
ORF1ab/nsp13154V154RV5478RnonsynGTaAGa210.516696-16698
ORF1ab/nsp13154V154RV5478RnonsynGTaCGa210.516696-16698
ORF1ab/nsp13154V154del2V5478del2delGTA--N11116696-16698
ORF1ab/nsp13154V154TV5478TnonsynGTAACG11116696-16698

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13154V154LGtaTta11981201All0.000229
ORF1ab/nsp13154V154LGtaCta31201All0.000001
ORF1ab/nsp13154V154LGtaTta322322AY.290.005079
ORF1ab/nsp13154V154LGtaTta243243B.1.617.20.000915
ORF1ab/nsp13154V154LGtaTta178178AY.1200.006618
ORF1ab/nsp13154V154VgtAgtG162174All0.000031
ORF1ab/nsp13154V154VgtAgtT7174All0.000001
ORF1ab/nsp13154V154VgtAgtC5174All0.000001
ORF1ab/nsp13154V154AgTagCa144144All0.000028
ORF1ab/nsp13154V154delGTA---9696All0.000018
ORF1ab/nsp13154V154LGtaTta7676B.1.6030.808511
ORF1ab/nsp13154V154delGTA---6262B.1.1.70.000056
ORF1ab/nsp13154V154IGtaAta5456All0.00001
ORF1ab/nsp13154V154IGtAAtT256All0
ORF1ab/nsp13154V154LGtaTta5555AY.40.000086
ORF1ab/nsp13154V154LGtaTta4747AY.440.000286
ORF1ab/nsp13154V154LGtaTta3939AY.430.000173
ORF1ab/nsp13154V154AgTagCa3939B.1.1.70.000035
ORF1ab/nsp13154V154VgtAgtG3636B.1.1.70.000032
ORF1ab/nsp13154V154AgTagCa3434AY.40.000053
ORF1ab/nsp13154V154LGtaTta2425B.1.1.70.000021
ORF1ab/nsp13154V154LGtaCta125B.1.1.70.000001
ORF1ab/nsp13154V154VgtAgtG2223P.10.000347
ORF1ab/nsp13154V154VgtAgtT123P.10.000016
ORF1ab/nsp13154V154VgtAgtG2121B.1.6210.001859
ORF1ab/nsp13154V154AgTagCa1919B.1.617.20.000072
ORF1ab/nsp13154V154LGtaTta1818AY.1180.001128
ORF1ab/nsp13154V154LGtaTta1818AY.30.000179
ORF1ab/nsp13154V154LGtaTta1717AY.390.00042
ORF1ab/nsp13154V154LGtaTta1616AY.46.40.002632
ORF1ab/nsp13154V154LGtaTta1414A.2.5.10.067308
ORF1ab/nsp13154V154VgtAgtG1414AY.40.000022
ORF1ab/nsp13154V154delGTA---1313B.1.1770.000171
ORF1ab/nsp13154V154VgtAgtG1011B.1.20.000088
ORF1ab/nsp13154V154VgtAgtT111B.1.20.000009
ORF1ab/nsp13154V154LGtaTta1010AY.1030.000062
ORF1ab/nsp13154V154LGtaTta1010AY.50.000206
ORF1ab/nsp13154V154VgtAgtG910B.1.10.000163
ORF1ab/nsp13154V154VgtAgtT110B.1.10.000018
ORF1ab/nsp13154V154LGtaTta88B.1.20.00007
ORF1ab/nsp13154V154LGtaTta77AY.250.000042
ORF1ab/nsp13154V154LGtaTta77AY.450.000852
ORF1ab/nsp13154V154LGtaTta67B.10.000055
ORF1ab/nsp13154V154LGtaCta17B.10.000009
ORF1ab/nsp13154V154VgtAgtG77B.1.1.3180.002112
ORF1ab/nsp13154V154VgtAgtG57B.1.617.20.000019
ORF1ab/nsp13154V154VgtAgtT17B.1.617.20.000004
ORF1ab/nsp13154V154VgtAgtC17B.1.617.20.000004
ORF1ab/nsp13154V154GgTagGa46All0.000001
ORF1ab/nsp13154V154GgTAgGC26All0
ORF1ab/nsp13154V154AgTagCa66AY.1020.000159
ORF1ab/nsp13154V154AgTagCa66AY.440.000037
ORF1ab/nsp13154V154IGtaAta66AY.460.000624
ORF1ab/nsp13154V154LGtaTta55AY.1020.000133
ORF1ab/nsp13154V154LGtaTta55AY.1190.000177
ORF1ab/nsp13154V154IGtaAta55B.1.1.70.000004
ORF1ab/nsp13154V154delGTA---44AD.20.000876
ORF1ab/nsp13154V154del1Gta-ta44All0.000001
ORF1ab/nsp13154V154IGtaAta44AY.250.000024
ORF1ab/nsp13154V154IGtaAta44AY.40.000006
ORF1ab/nsp13154V154AgTagCa44AY.670.001857
ORF1ab/nsp13154V154LGtaTta44B.1.10.000073
ORF1ab/nsp13154V154LGtaTta44B.1.1.2220.000816
ORF1ab/nsp13154V154IGtaAta44B.1.1.3690.001785
ORF1ab/nsp13154V154AgTagCa44B.1.20.000035
ORF1ab/nsp13154V154VgtAgtG44B.1.4270.000202
ORF1ab/nsp13154V154AgTagCa44B.1.5950.001044
ORF1ab/nsp13154V154AgTagCa33AY.1030.000019
ORF1ab/nsp13154V154AgTagCa33AY.250.000018
ORF1ab/nsp13154V154LGtaTta33AY.29.10.000662
ORF1ab/nsp13154V154LGtaTta33AY.34.10.00153
ORF1ab/nsp13154V154AgTagCa33AY.430.000013
ORF1ab/nsp13154V154IGtaAta33AY.470.000093
ORF1ab/nsp13154V154VgtAgtG33AY.750.000168
ORF1ab/nsp13154V154LGtaTta33B.1.1770.00004
ORF1ab/nsp13154V154VgtAgtG33B.1.617.10.000387
ORF1ab/nsp13154V154LGtaTta33C.370.000348
ORF1ab/nsp13154V154LGtaTta23P.10.000032
ORF1ab/nsp13154V154LGtaCta13P.10.000016
ORF1ab/nsp13154V154LGtaTta33P.1.150.000697
ORF1ab/nsp13154V154SGTaTCa220.111111
ORF1ab/nsp13154V154delGTA---220.111111
ORF1ab/nsp13154V154GgTAgGC220.111111
ORF1ab/nsp13154V154VgtAgtC220.111111
ORF1ab/nsp13154V154IGtAAtT220.111111
ORF1ab/nsp13154V154EgTagAa22All0
ORF1ab/nsp13154V154SGTaTCa22All0
ORF1ab/nsp13154V154RGTaCGa12All0
ORF1ab/nsp13154V154RGTaAGa12All0
ORF1ab/nsp13154V154LGtaTta22AY.160.000759
ORF1ab/nsp13154V154LGtaTta22AY.230.000139
ORF1ab/nsp13154V154LGtaTta22AY.330.000134
ORF1ab/nsp13154V154IGtaAta22AY.360.000296
ORF1ab/nsp13154V154LGtaTta22AY.4.20.000043
ORF1ab/nsp13154V154IGtaAta22AY.420.00008
ORF1ab/nsp13154V154VgtAgtG22AY.430.000009
ORF1ab/nsp13154V154LGtaTta22AY.60.000082
ORF1ab/nsp13154V154LGtaTta22AY.980.000158
ORF1ab/nsp13154V154LGtaTta22AY.98.10.000097
ORF1ab/nsp13154V154IGtaAta22B.10.000018
ORF1ab/nsp13154V154delGTA---22B.10.000018
ORF1ab/nsp13154V154AgTagCa22B.10.000018
ORF1ab/nsp13154V154VgtAgtC12B.10.000009
ORF1ab/nsp13154V154VgtAgtG12B.10.000009
ORF1ab/nsp13154V154AgTagCa22B.1.1.3180.000604
ORF1ab/nsp13154V154VgtAgtG22B.1.1030.038462
ORF1ab/nsp13154V154LGtaTta22B.1.110.30.001437
ORF1ab/nsp13154V154EgTagAa22B.1.1770.000026
ORF1ab/nsp13154V154VgtAgtG22B.1.1770.000026
ORF1ab/nsp13154V154IGtaAta22B.1.1770.000026
ORF1ab/nsp13154V154IGtaAta22B.1.177.280.014815
ORF1ab/nsp13154V154AgTagCa22B.1.5090.001732
ORF1ab/nsp13154V154IGtaAta22B.1.617.20.000008
ORF1ab/nsp13154V154RGTaCGa12P.10.000016
ORF1ab/nsp13154V154RGTaAGa12P.10.000016
ORF1ab/nsp13154V154VgtAgtG11AD.20.000219
ORF1ab/nsp13154V154TGTAACG11All0
ORF1ab/nsp13154V154del2GTA--N11All0
ORF1ab/nsp13154V154IGtaAta11AY.1030.000006
ORF1ab/nsp13154V154VgtAgtG11AY.1030.000006
ORF1ab/nsp13154V154IGtaAta11AY.1100.000113
ORF1ab/nsp13154V154VgtAgtG11AY.1110.000183
ORF1ab/nsp13154V154IGtaAta11AY.1170.000085
ORF1ab/nsp13154V154AgTagCa11AY.1190.000035
ORF1ab/nsp13154V154VgtAgtG11AY.1200.000037
ORF1ab/nsp13154V154VgtAgtG11AY.120.10.000321
ORF1ab/nsp13154V154LGtaTta11AY.120.20.001285
ORF1ab/nsp13154V154del1Gta-ta11AY.160.00038
ORF1ab/nsp13154V154VgtAgtT11AY.16.10.00047
ORF1ab/nsp13154V154IGtaAta11AY.230.00007
ORF1ab/nsp13154V154VgtAgtG11AY.23.10.000417
ORF1ab/nsp13154V154IGtaAta11AY.240.000431
ORF1ab/nsp13154V154delGTA---11AY.240.000431
ORF1ab/nsp13154V154VgtAgtG11AY.250.000006
ORF1ab/nsp13154V154LGtaTta11AY.260.000028
ORF1ab/nsp13154V154IGtaAta11AY.260.000028
ORF1ab/nsp13154V154LGtaTta11AY.340.000097
ORF1ab/nsp13154V154LGtaTta11AY.360.000148
ORF1ab/nsp13154V154VgtAgtG11AY.360.000148
ORF1ab/nsp13154V154VgtAgtG11AY.390.000025
ORF1ab/nsp13154V154IGtaAta11AY.390.000025
ORF1ab/nsp13154V154LGtaTta11AY.39.20.001541
ORF1ab/nsp13154V154VgtAgtG11AY.4.20.000022
ORF1ab/nsp13154V154IGtaAta11AY.4.20.000022
ORF1ab/nsp13154V154LGtaTta11AY.4.50.000107
ORF1ab/nsp13154V154IGtaAta11AY.430.000004
ORF1ab/nsp13154V154LGtaTta11AY.46.10.001027
ORF1ab/nsp13154V154LGtaTta11AY.46.20.000635
ORF1ab/nsp13154V154LGtaTta11AY.470.000031
ORF1ab/nsp13154V154LGtaTta11AY.5.20.002463
ORF1ab/nsp13154V154LGtaTta11AY.5.40.000277
ORF1ab/nsp13154V154LGtaTta11AY.540.000095
ORF1ab/nsp13154V154VgtAgtG11AY.590.00053
ORF1ab/nsp13154V154IGtaAta11AY.60.000041
ORF1ab/nsp13154V154LGtaTta11AY.610.000105
ORF1ab/nsp13154V154VgtAgtT11AY.610.000105
ORF1ab/nsp13154V154LGtaTta11AY.620.000436
ORF1ab/nsp13154V154VgtAgtG11AY.680.000274
ORF1ab/nsp13154V154LGtaTta11AY.700.000209
ORF1ab/nsp13154V154AgTagCa11AY.840.000437
ORF1ab/nsp13154V154VgtAgtG11AY.9.10.000084
ORF1ab/nsp13154V154IGtaAta11AY.980.000079
ORF1ab/nsp13154V154LGtaTta11AY.990.001049
ORF1ab/nsp13154V154delGTA---11AZ.20.000821
ORF1ab/nsp13154V154delGTA---11B.1.10.000018
ORF1ab/nsp13154V154VgtAgtG11B.1.1.2140.000055
ORF1ab/nsp13154V154delGTA---11B.1.1.2310.003096
ORF1ab/nsp13154V154AgTagCa11B.1.1.280.000311
ORF1ab/nsp13154V154LGtaTta11B.1.1.2840.000107
ORF1ab/nsp13154V154IGtaAta11B.1.1.2840.000107
ORF1ab/nsp13154V154delGTA---11B.1.1.3060.000438
ORF1ab/nsp13154V154delGTA---11B.1.1.3150.008475
ORF1ab/nsp13154V154VgtAgtG11B.1.1.330.000421
ORF1ab/nsp13154V154AgTagCa11B.1.1.390.00051
ORF1ab/nsp13154V154LGtaTta11B.1.1.4130.006897
ORF1ab/nsp13154V154delGTA---11B.1.1.440.00241
ORF1ab/nsp13154V154LGtaTta11B.1.1.5190.00004
ORF1ab/nsp13154V154del2GTA--N11B.1.1.70.000001
ORF1ab/nsp13154V154del1Gta-ta11B.1.1.70.000001
ORF1ab/nsp13154V154VgtAgtG11B.1.1570.002985
ORF1ab/nsp13154V154LGtaTta11B.1.1600.000031
ORF1ab/nsp13154V154LGtaTta11B.1.160.160.000929
ORF1ab/nsp13154V154delGTA---11B.1.160.170.001701
ORF1ab/nsp13154V154GgTagGa11B.1.1770.000013
ORF1ab/nsp13154V154VgtAgtT11B.1.177.530.002392
ORF1ab/nsp13154V154delGTA---11B.1.177.730.000566
ORF1ab/nsp13154V154delGTA---11B.1.177.830.001481
ORF1ab/nsp13154V154LGtaTta11B.1.1920.009259
ORF1ab/nsp13154V154IGtaAta11B.1.1940.04
ORF1ab/nsp13154V154del1Gta-ta11B.1.20.000009
ORF1ab/nsp13154V154GgTagGa11B.1.20.000009
ORF1ab/nsp13154V154del1Gta-ta11B.1.2060.000816
ORF1ab/nsp13154V154delGTA---11B.1.2420.018868
ORF1ab/nsp13154V154AgTagCa11B.1.2430.00007
ORF1ab/nsp13154V154LGtaTta11B.1.2430.00007
ORF1ab/nsp13154V154IGtaAta11B.1.3510.00003
ORF1ab/nsp13154V154LGtaTta11B.1.360.000146
ORF1ab/nsp13154V154delGTA---11B.1.360.000146
ORF1ab/nsp13154V154VgtAgtG11B.1.3620.001541
ORF1ab/nsp13154V154AgTagCa11B.1.4000.000429
ORF1ab/nsp13154V154IGtaAta11B.1.4040.001302
ORF1ab/nsp13154V154LGtaTta11B.1.4270.00005
ORF1ab/nsp13154V154AgTagCa11B.1.4290.000024
ORF1ab/nsp13154V154LGtaTta11B.1.4290.000024
ORF1ab/nsp13154V154IGtaAta11B.1.4970.000315
ORF1ab/nsp13154V154LGtaTta11B.1.5260.000024
ORF1ab/nsp13154V154LGtaTta11B.1.5820.000491
ORF1ab/nsp13154V154AgTagCa11B.1.617.10.000129
ORF1ab/nsp13154V154TGTAACG11B.1.617.20.000004
ORF1ab/nsp13154V154LGtaTta11B.1.617.30.002985
ORF1ab/nsp13154V154VgtAgtG11B.1.619.10.000641
ORF1ab/nsp13154V154GgTagGa11B.1.621.10.000506
ORF1ab/nsp13154V154VgtAgtC11B.1.6230.000536
ORF1ab/nsp13154V154VgtAgtG11B.1.6280.000352
ORF1ab/nsp13154V154VgtAgtG11B.60.00091
ORF1ab/nsp13154V154LGtaTta11B.610.005747
ORF1ab/nsp13154V154AgTagCa11C.360.000911
ORF1ab/nsp13154V154LGtaTta11D.20.000075
ORF1ab/nsp13154V154LGtaTta11D.30.005917
ORF1ab/nsp13154V154GgTagGa11P.10.000016
ORF1ab/nsp13154V154AgTagCa11P.10.000016
ORF1ab/nsp13154V154VgtAgtG11P.1.120.000484
ORF1ab/nsp13154V154AgTagCa11P.1.170.000162
ORF1ab/nsp13154V154delGTA---11Q.10.000126
ORF1ab/nsp13154V154AgTagCa11Q.40.000455
ORF1ab/nsp13154V154AgTagCa11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.