CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : CodonNum = 151 & Codon = aGt

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF1ab/nsp13	151	I151S	I5475S	nonsyn	aTt	aGt	321	319	0.993769	16687-16689

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF1ab/nsp13	151	I151S	aTt	aGt	319	321	All	0.000061
ORF1ab/nsp13	151	I151S	aTt	aGt	289	289	AY.4	0.00045
ORF1ab/nsp13	151	I151S	aTt	aGt	10	10	B.1.1.7	0.000009
ORF1ab/nsp13	151	I151S	aTt	aGt	7	7	B.1.617.2	0.000026
ORF1ab/nsp13	151	I151S	aTt	aGt	3	3	AY.43	0.000013
ORF1ab/nsp13	151	I151S	aTt	aGt	2	2	AY.44	0.000012
ORF1ab/nsp13	151	I151S	aTt	aGt	1	2	B.1.1	0.000018
ORF1ab/nsp13	151	I151S	aTt	aGt	2	2	B.1.177.85	0.01087
ORF1ab/nsp13	151	I151S	aTt	aGt	1	1	AY.45	0.000122
ORF1ab/nsp13	151	I151S	aTt	aGt	1	1	AY.5	0.000021
ORF1ab/nsp13	151	I151S	aTt	aGt	1	1	AY.9.2	0.000037
ORF1ab/nsp13	151	I151S	aTt	aGt	1	1	B.1.1.369	0.000446
ORF1ab/nsp13	151	I151S	aTt	aGt	1	1	B.6.6	0.000889

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.