CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp13 : CodonNum = 124

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp13124N124NN5448NsynaaCaaT16521652116606-16608
ORF1ab/nsp13124N124delN5448deldelAAC---211211116606-16608
ORF1ab/nsp13124N124SN5448SnonsynaAcaGc207207116606-16608
ORF1ab/nsp13124N124DN5448DnonsynAacGac72710.98611116606-16608
ORF1ab/nsp13124N124DN5448DnonsynAaCGaT7210.013888916606-16608
ORF1ab/nsp13124N124IN5448InonsynaAcaTc19180.94736816606-16608
ORF1ab/nsp13124N124IN5448InonsynaACaTT1910.052631616606-16608
ORF1ab/nsp13124N124TN5448TnonsynaAcaCc1515116606-16608
ORF1ab/nsp13124N124KN5448KnonsynaaCaaA540.816606-16608
ORF1ab/nsp13124N124KN5448KnonsynaaCaaG510.216606-16608
ORF1ab/nsp13124N124HN5448HnonsynAaCCaT430.7516606-16608
ORF1ab/nsp13124N124HN5448HnonsynAacCac410.2516606-16608
ORF1ab/nsp13124N124GN5448GnonsynAACGGT22116606-16608
ORF1ab/nsp13124N124del1N5448del1delAAC-TT210.516606-16608
ORF1ab/nsp13124N124VN5448VnonsynAACGTT210.516606-16608
ORF1ab/nsp13124N124VN5448VnonsynAAcGTc210.516606-16608
ORF1ab/nsp13124N124del1N5448del1delaaCaa-210.516606-16608
ORF1ab/nsp13124N124del2N5448del2delAAC--N11116606-16608
ORF1ab/nsp13124N124QN5448QnonsynAaCCaG11116606-16608

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp13124N124NaaCaaT16521652All0.000316
ORF1ab/nsp13124N124NaaCaaT606606B.1.1.70.000543
ORF1ab/nsp13124N124NaaCaaT263263AY.9.20.00966
ORF1ab/nsp13124N124NaaCaaT250250AY.440.001522
ORF1ab/nsp13124N124delAAC---211211All0.00004
ORF1ab/nsp13124N124SaAcaGc207207All0.00004
ORF1ab/nsp13124N124delAAC---134134B.1.1.70.00012
ORF1ab/nsp13124N124NaaCaaT7676AY.290.001199
ORF1ab/nsp13124N124DAacGac7172All0.000014
ORF1ab/nsp13124N124DAaCGaT172All0
ORF1ab/nsp13124N124SaAcaGc5454AY.50.001115
ORF1ab/nsp13124N124SaAcaGc5252P.1.170.008412
ORF1ab/nsp13124N124NaaCaaT5050B.1.617.20.000188
ORF1ab/nsp13124N124DAacGac4444B.1.4290.001035
ORF1ab/nsp13124N124NaaCaaT4242AY.430.000186
ORF1ab/nsp13124N124NaaCaaT3939AY.40.000061
ORF1ab/nsp13124N124NaaCaaT3535C.370.004062
ORF1ab/nsp13124N124SaAcaGc2626B.1.1.1970.962963
ORF1ab/nsp13124N124delAAC---2121B.1.1770.000277
ORF1ab/nsp13124N124IaAcaTc1819All0.000003
ORF1ab/nsp13124N124IaACaTT119All0
ORF1ab/nsp13124N124NaaCaaT1818AY.4.20.00039
ORF1ab/nsp13124N124NaaCaaT1717AY.90.001149
ORF1ab/nsp13124N124NaaCaaT1717B.1.617.10.002192
ORF1ab/nsp13124N124NaaCaaT1616B.1.3510.000476
ORF1ab/nsp13124N124TaAcaCc1515All0.000003
ORF1ab/nsp13124N124NaaCaaT1414AY.1030.000087
ORF1ab/nsp13124N124SaAcaGc1414B.1.1.70.000013
ORF1ab/nsp13124N124NaaCaaT1414B.1.1770.000184
ORF1ab/nsp13124N124NaaCaaT1414B.1.6370.001023
ORF1ab/nsp13124N124NaaCaaT1313B.1.177.810.002461
ORF1ab/nsp13124N124IaAcaTc1212B.1.1.3760.071429
ORF1ab/nsp13124N124NaaCaaT1111AY.30.000109
ORF1ab/nsp13124N124DAacGac99B.10.000082
ORF1ab/nsp13124N124delAAC---99B.1.10.000163
ORF1ab/nsp13124N124NaaCaaT88AY.980.000632
ORF1ab/nsp13124N124SaAcaGc77AY.260.000198
ORF1ab/nsp13124N124NaaCaaT77B.1.10.000127
ORF1ab/nsp13124N124NaaCaaT77B.1.466.20.002739
ORF1ab/nsp13124N124TaAcaCc77P.1.140.000335
ORF1ab/nsp13124N124NaaCaaT66AY.250.000036
ORF1ab/nsp13124N124delAAC---55AD.20.001095
ORF1ab/nsp13124N124KaaCaaA45All0.000001
ORF1ab/nsp13124N124KaaCaaG15All0
ORF1ab/nsp13124N124NaaCaaT55AY.1020.000133
ORF1ab/nsp13124N124SaAcaGc55AY.140.00044
ORF1ab/nsp13124N124SaAcaGc55AY.30.00005
ORF1ab/nsp13124N124NaaCaaT55AY.4.10.003687
ORF1ab/nsp13124N124NaaCaaT55AY.46.40.000823
ORF1ab/nsp13124N124delAAC---55AZ.20.004105
ORF1ab/nsp13124N124NaaCaaT55B.10.000046
ORF1ab/nsp13124N124NaaCaaT55B.1.20.000044
ORF1ab/nsp13124N124delAAC---440.222222
ORF1ab/nsp13124N124HAaCCaT34All0.000001
ORF1ab/nsp13124N124HAacCac14All0
ORF1ab/nsp13124N124NaaCaaT44AY.200.000155
ORF1ab/nsp13124N124NaaCaaT44AY.470.000124
ORF1ab/nsp13124N124NaaCaaT44AY.530.00115
ORF1ab/nsp13124N124NaaCaaT44AY.60.000165
ORF1ab/nsp13124N124NaaCaaT44AY.610.000419
ORF1ab/nsp13124N124NaaCaaT44B.1.1.5190.000159
ORF1ab/nsp13124N124NaaCaaT44B.1.4270.000202
ORF1ab/nsp13124N124SaAcaGc44B.1.617.20.000015
ORF1ab/nsp13124N124NaaCaaT33AY.270.000194
ORF1ab/nsp13124N124NaaCaaT33AY.390.000074
ORF1ab/nsp13124N124NaaCaaT33AY.39.10.000119
ORF1ab/nsp13124N124SaAcaGc33AY.40.000005
ORF1ab/nsp13124N124delAAC---33B.10.000027
ORF1ab/nsp13124N124NaaCaaT33B.1.1.1570.00274
ORF1ab/nsp13124N124SaAcaGc33B.1.1.1570.00274
ORF1ab/nsp13124N124SaAcaGc33B.1.1.2140.000166
ORF1ab/nsp13124N124DAacGac33B.1.1.70.000003
ORF1ab/nsp13124N124SaAcaGc33B.1.1770.00004
ORF1ab/nsp13124N124SaAcaGc33B.1.20.000026
ORF1ab/nsp13124N124NaaCaaT33B.1.5260.000071
ORF1ab/nsp13124N124NaaCaaT33P.10.000047
ORF1ab/nsp13124N124delAAC---33Q.10.000379
ORF1ab/nsp13124N124GAACGGT220.111111
ORF1ab/nsp13124N124HAaCCaT12A.2.40.003367
ORF1ab/nsp13124N124HAacCac12A.2.40.003367
ORF1ab/nsp13124N124GAACGGT22All0
ORF1ab/nsp13124N124del1aaCaa-12All0
ORF1ab/nsp13124N124VAACGTT12All0
ORF1ab/nsp13124N124del1AAC-TT12All0
ORF1ab/nsp13124N124VAAcGTc12All0
ORF1ab/nsp13124N124NaaCaaT22AY.230.000139
ORF1ab/nsp13124N124SaAcaGc22AY.390.000049
ORF1ab/nsp13124N124TaAcaCc22AY.40.000003
ORF1ab/nsp13124N124SaAcaGc22AY.5.40.000553
ORF1ab/nsp13124N124NaaCaaT22AY.720.002721
ORF1ab/nsp13124N124NaaCaaT22AY.740.000231
ORF1ab/nsp13124N124NaaCaaT22AY.75.10.000361
ORF1ab/nsp13124N124SaAcaGc22B.10.000018
ORF1ab/nsp13124N124SaAcaGc22B.1.10.000036
ORF1ab/nsp13124N124IaAcaTc12B.1.10.000018
ORF1ab/nsp13124N124IaACaTT12B.1.10.000018
ORF1ab/nsp13124N124VAAcGTc12B.1.10.000018
ORF1ab/nsp13124N124DAacGac12B.1.10.000018
ORF1ab/nsp13124N124VAACGTT12B.1.10.000018
ORF1ab/nsp13124N124DAaCGaT12B.1.10.000018
ORF1ab/nsp13124N124NaaCaaT22B.1.1.2220.000408
ORF1ab/nsp13124N124delAAC---22B.1.1.3050.007722
ORF1ab/nsp13124N124delAAC---22B.1.1.3150.016949
ORF1ab/nsp13124N124DAacGac22B.1.1.3180.000604
ORF1ab/nsp13124N124delAAC---22B.1.1.440.004819
ORF1ab/nsp13124N124NaaCaaT22B.1.177.470.025974
ORF1ab/nsp13124N124NaaCaaT22B.1.2580.000133
ORF1ab/nsp13124N124DAacGac22B.1.3510.000059
ORF1ab/nsp13124N124NaaCaaT22B.1.3770.009132
ORF1ab/nsp13124N124NaaCaaT22B.1.3810.015625
ORF1ab/nsp13124N124DAacGac22B.1.4620.014493
ORF1ab/nsp13124N124TaAcaCc22B.1.617.20.000008
ORF1ab/nsp13124N124NaaCaaT22B.400.000729
ORF1ab/nsp13124N124NaaCaaT22D.20.00015
ORF1ab/nsp13124N124SaAcaGc22P.10.000032
ORF1ab/nsp13124N124NaaCaaT22P.1.140.000096
ORF1ab/nsp13124N124HAaCCaT11A.10.000282
ORF1ab/nsp13124N124NaaCaaT11A.20.000662
ORF1ab/nsp13124N124NaaCaaT11A.2.40.003367
ORF1ab/nsp13124N124SaAcaGc11A.2.40.003367
ORF1ab/nsp13124N124NaaCaaT11A.2.50.000499
ORF1ab/nsp13124N124QAaCCaG11All0
ORF1ab/nsp13124N124del2AAC--N11All0
ORF1ab/nsp13124N124TaAcaCc11AY.1000.000046
ORF1ab/nsp13124N124NaaCaaT11AY.1010.00049
ORF1ab/nsp13124N124SaAcaGc11AY.1030.000006
ORF1ab/nsp13124N124NaaCaaT11AY.110.001339
ORF1ab/nsp13124N124NaaCaaT11AY.1190.000035
ORF1ab/nsp13124N124NaaCaaT11AY.130.000161
ORF1ab/nsp13124N124delAAC---11AY.240.000431
ORF1ab/nsp13124N124SaAcaGc11AY.250.000006
ORF1ab/nsp13124N124DAacGac11AY.260.000028
ORF1ab/nsp13124N124NaaCaaT11AY.330.000067
ORF1ab/nsp13124N124HAaCCaT11AY.330.000067
ORF1ab/nsp13124N124delAAC---11AY.40.000002
ORF1ab/nsp13124N124TaAcaCc11AY.430.000004
ORF1ab/nsp13124N124delAAC---11AY.430.000004
ORF1ab/nsp13124N124SaAcaGc11AY.430.000004
ORF1ab/nsp13124N124SaAcaGc11AY.440.000006
ORF1ab/nsp13124N124TaAcaCc11AY.440.000006
ORF1ab/nsp13124N124delAAC---11AY.440.000006
ORF1ab/nsp13124N124NaaCaaT11AY.460.000104
ORF1ab/nsp13124N124NaaCaaT11AY.46.10.001027
ORF1ab/nsp13124N124NaaCaaT11AY.550.000917
ORF1ab/nsp13124N124NaaCaaT11AY.560.001605
ORF1ab/nsp13124N124NaaCaaT11AY.680.000274
ORF1ab/nsp13124N124delAAC---11AY.90.000068
ORF1ab/nsp13124N124NaaCaaT11AY.9.10.000084
ORF1ab/nsp13124N124SaAcaGc11AY.9.20.000037
ORF1ab/nsp13124N124NaaCaaT11AY.940.000443
ORF1ab/nsp13124N124SaAcaGc11AY.990.001049
ORF1ab/nsp13124N124SaAcaGc11AY.99.20.000092
ORF1ab/nsp13124N124IaAcaTc11B.1.1.1810.004545
ORF1ab/nsp13124N124delAAC---11B.1.1.1970.037037
ORF1ab/nsp13124N124delAAC---11B.1.1.2310.003096
ORF1ab/nsp13124N124DAacGac11B.1.1.2580.003257
ORF1ab/nsp13124N124NaaCaaT11B.1.1.280.000311
ORF1ab/nsp13124N124del2AAC--N11B.1.1.3050.003861
ORF1ab/nsp13124N124delAAC---11B.1.1.3060.000438
ORF1ab/nsp13124N124QAaCCaG11B.1.1.3060.000438
ORF1ab/nsp13124N124delAAC---11B.1.1.3180.000302
ORF1ab/nsp13124N124NaaCaaT11B.1.1.3510.002793
ORF1ab/nsp13124N124delAAC---11B.1.1.510.001718
ORF1ab/nsp13124N124delAAC---11B.1.1.5190.00004
ORF1ab/nsp13124N124delAAC---11B.1.1.5210.005348
ORF1ab/nsp13124N124del1aaCaa-11B.1.1.70.000001
ORF1ab/nsp13124N124TaAcaCc11B.1.1.70.000001
ORF1ab/nsp13124N124KaaCaaA11B.1.1.70.000001
ORF1ab/nsp13124N124delAAC---11B.1.1400.018868
ORF1ab/nsp13124N124SaAcaGc11B.1.1600.000031
ORF1ab/nsp13124N124NaaCaaT11B.1.1600.000031
ORF1ab/nsp13124N124NaaCaaT11B.1.160.160.000929
ORF1ab/nsp13124N124delAAC---11B.1.160.230.004831
ORF1ab/nsp13124N124IaAcaTc11B.1.1690.014925
ORF1ab/nsp13124N124del1AAC-TT11B.1.1770.000013
ORF1ab/nsp13124N124NaaCaaT11B.1.177.120.000152
ORF1ab/nsp13124N124NaaCaaT11B.1.177.40.000211
ORF1ab/nsp13124N124SaAcaGc11B.1.177.560.000668
ORF1ab/nsp13124N124delAAC---11B.1.177.730.000566
ORF1ab/nsp13124N124delAAC---11B.1.177.830.001481
ORF1ab/nsp13124N124delAAC---11B.1.20.000009
ORF1ab/nsp13124N124DAacGac11B.1.20.000009
ORF1ab/nsp13124N124DAacGac11B.1.2210.000071
ORF1ab/nsp13124N124SaAcaGc11B.1.2400.000216
ORF1ab/nsp13124N124delAAC---11B.1.2420.018868
ORF1ab/nsp13124N124NaaCaaT11B.1.2430.00007
ORF1ab/nsp13124N124NaaCaaT11B.1.258.160.001637
ORF1ab/nsp13124N124NaaCaaT11B.1.3110.000275
ORF1ab/nsp13124N124IaAcaTc11B.1.3110.000275
ORF1ab/nsp13124N124KaaCaaA11B.1.3510.00003
ORF1ab/nsp13124N124NaaCaaT11B.1.360.000146
ORF1ab/nsp13124N124delAAC---11B.1.360.000146
ORF1ab/nsp13124N124delAAC---11B.1.416.10.001563
ORF1ab/nsp13124N124SaAcaGc11B.1.4290.000024
ORF1ab/nsp13124N124NaaCaaT11B.1.438.10.000107
ORF1ab/nsp13124N124IaAcaTc11B.1.4970.000315
ORF1ab/nsp13124N124KaaCaaA11B.1.4970.000315
ORF1ab/nsp13124N124DAacGac11B.1.5050.004386
ORF1ab/nsp13124N124SaAcaGc11B.1.5260.000024
ORF1ab/nsp13124N124NaaCaaT11B.1.5610.000397
ORF1ab/nsp13124N124NaaCaaT11B.1.5900.004545
ORF1ab/nsp13124N124NaaCaaT11B.1.5950.000261
ORF1ab/nsp13124N124NaaCaaT11B.1.5960.000087
ORF1ab/nsp13124N124delAAC---11B.1.617.10.000129
ORF1ab/nsp13124N124KaaCaaA11B.1.617.20.000004
ORF1ab/nsp13124N124IaAcaTc11B.1.617.20.000004
ORF1ab/nsp13124N124DAacGac11B.1.617.20.000004
ORF1ab/nsp13124N124DAacGac11B.30.000831
ORF1ab/nsp13124N124DAacGac11P.10.000016
ORF1ab/nsp13124N124KaaCaaG11P.10.000016
ORF1ab/nsp13124N124SaAcaGc11P.1.100.000269
ORF1ab/nsp13124N124NaaCaaT11P.1.130.000898
ORF1ab/nsp13124N124SaAcaGc11P.1.150.000232
ORF1ab/nsp13124N124NaaCaaT11P.20.000187
ORF1ab/nsp13124N124NaaCaaT11Q.40.000455
ORF1ab/nsp13124N124NaaCaaT11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.